PMV Pharmaceuticals (PMVP) vs Spruce Biosciences (SPRB)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 7, 2026.
Summary
PMV Pharmaceuticals (PMVP) has outperformed Spruce Biosciences (SPRB) over the past year, gaining 10.3% versus a loss of 75.7%. Over five years, PMVP leads with a -93.7% price change compared with -99.8% for SPRB. Spruce Biosciences is the larger company by market cap ($127.6 million vs $113.3 million), about 1.1 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | PMVP | SPRB |
|---|---|---|
| Share price | $1.50 | $44.40 |
| Market cap | $113.27M | $127.61M |
| 1-day change | -6.83% | +3.77% |
| YTD return | +20.00% | -49.03% |
| 1-year return | +10.29% | -75.68% |
| 5-year return | -93.74% | -99.82% |
| Forward P/E | — | 8.92 |
| EPS (TTM) | $-1.42 | $-39.12 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $1.91 | $199.20 |
| 52-week low | $1.02 | $40.33 |
| Distance from 52-week high | -21.47% | -77.71% |
| Average volume | 652.32K | 77.72K |
| Shares outstanding | 75.51M | 2.87M |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- PMVP has outperformed SPRB by 86.0 percentage points over the past year.
PMVP vs SPRB FAQ
Which is bigger, PMV Pharmaceuticals or Spruce Biosciences?
Spruce Biosciences (SPRB) is larger, with a market capitalization of $127.61M compared with $113.27M for PMV Pharmaceuticals (PMVP).
Which stock has performed better over the past year, PMVP or SPRB?
PMVP returned +10.29% over the past 12 months, compared with -75.68% for SPRB (price return, excluding dividends). Past performance does not predict future results.
Are PMV Pharmaceuticals and Spruce Biosciences in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.