MetaCap

ProKidney (PROK) vs REGENXBIO (RGNX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

REGENXBIO (RGNX) has outperformed ProKidney (PROK) over the past year, losing 27.7% versus a loss of 47.0%. Over five years, RGNX leads with a -78.9% price change compared with -84.1% for PROK. ProKidney is the larger company by market cap ($626.7 million vs $501.4 million), about 1.3 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

PROK-46.96%RGNX-27.74%
+57%-2%-60%
Oct 7, 20251 yearOct 7, 2026
PROK-84.01%RGNX-76.02%
+38%-31%-100%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

PROK versus RGNX key metrics
MetricPROKRGNX
Share price$1.57$7.60
Market cap$626.72M$501.37M
1-day change-1.88%+1.95%
YTD return-29.91%-47.26%
1-year return-46.96%-27.74%
5-year return-84.09%-78.87%
EPS (TTM)$-0.55$-3.78
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$3.48$16.19
52-week low$1.30$5.46
Distance from 52-week high-54.89%-53.09%
Analyst consensusnonebuy
Avg. price target upside+298.09%+210.47%
Average volume1.30M1.52M
Shares outstanding208.93M66.01M
Employees231371
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • RGNX has outperformed PROK by 19.2 percentage points over the past year.

About ProKidney

PROK stock →

ProKidney Corp., a clinical-stage biotechnology company, engages in the development of cell therapies for the treatment of chronic kidney diseases in the United States. The company develops rilparencel, a cell therapy with autologous selected renal cells, which is in Phase III clinical trial for the treatment of advanced chronic kidney disease and type 2 diabetes.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 231 employees

About REGENXBIO

RGNX stock →

REGENXBIO Inc., a clinical-stage biotechnology company, provides gene therapies that deliver functional genes to cells with genetic defects in the United States. Its gene therapy product candidates are based on NAV Technology Platform, a proprietary adeno-associated virus gene delivery platform.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 371 employees

PROK vs RGNX FAQ

Which is bigger, ProKidney or REGENXBIO?

ProKidney (PROK) is larger, with a market capitalization of $626.72M compared with $501.37M for REGENXBIO (RGNX).

Which stock has performed better over the past year, PROK or RGNX?

RGNX returned -27.74% over the past 12 months, compared with -46.96% for PROK (price return, excluding dividends). Past performance does not predict future results.

Are ProKidney and REGENXBIO in the same industry?

Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.

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