MetaCap

ProKidney (PROK) vs Tectonic Therapeutic (TECX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Tectonic Therapeutic (TECX) has outperformed ProKidney (PROK) over the past year, gaining 52.3% versus a loss of 47.0%. Over five years, TECX leads with a -67.4% price change compared with -84.1% for PROK. ProKidney is the larger company by market cap ($636.7 million vs $425.4 million), about 1.5 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

PROK-46.96%TECX+52.31%
+165%+50%-66%
Oct 7, 20251 yearOct 7, 2026
PROK-84.01%TECX-65.84%
+38%-33%-104%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

PROK versus TECX key metrics
MetricPROKTECX
Share price$1.60$21.76
Market cap$636.70M$425.39M
1-day change+1.59%-4.18%
YTD return-29.91%+8.87%
1-year return-46.96%+52.31%
5-year return-84.09%-67.37%
EPS (TTM)$-0.55$-4.57
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$3.48$39.53
52-week low$1.30$15.32
Distance from 52-week high-54.17%-44.95%
Analyst consensusnonestrong_buy
Avg. price target upside+291.85%+252.16%
Average volume1.30M220.39K
Shares outstanding208.93M19.55M
Employees23160
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • TECX has outperformed PROK by 99.3 percentage points over the past year.

About ProKidney

PROK stock →

ProKidney Corp., a clinical-stage biotechnology company, engages in the development of cell therapies for the treatment of chronic kidney diseases in the United States. The company develops rilparencel, a cell therapy with autologous selected renal cells, which is in Phase III clinical trial for the treatment of advanced chronic kidney disease and type 2 diabetes.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 231 employees

About Tectonic Therapeutic

TECX stock →

Tectonic Therapeutic, Inc., a biotechnology company, focuses on the discovery and development of therapeutic proteins and antibodies to modulate the activity of G protein coupled receptors (GPCRs). It develops GEODe technology platform to enable the discovery and development of GPCR-targeted biologic medicines.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 60 employees

PROK vs TECX FAQ

Which is bigger, ProKidney or Tectonic Therapeutic?

ProKidney (PROK) is larger, with a market capitalization of $636.70M compared with $425.39M for Tectonic Therapeutic (TECX).

Which stock has performed better over the past year, PROK or TECX?

TECX returned +52.31% over the past 12 months, compared with -46.96% for PROK (price return, excluding dividends). Past performance does not predict future results.

Are ProKidney and Tectonic Therapeutic in the same industry?

Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.

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