MetaCap

Rezolute (RZLT) vs ARS Pharmaceuticals (SPRY)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Rezolute (RZLT) has outperformed ARS Pharmaceuticals (SPRY) over the past year, losing 50.0% versus a loss of 59.0%. Over five years, RZLT leads with a -34.1% price change compared with -55.8% for SPRY. ARS Pharmaceuticals is the larger company by market cap ($453.5 million vs $448.8 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

RZLT-50.00%SPRY-57.79%
+32%-29%-90%
Oct 7, 20251 yearOct 7, 2026
RZLT-40.97%SPRY-54.77%
+98%-0%-99%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

RZLT versus SPRY key metrics
MetricRZLTSPRY
Share price$4.64$4.56
Market cap$448.79M$453.48M
1-day change+5.94%+4.59%
YTD return+85.59%-60.86%
1-year return-50.00%-58.96%
5-year return-34.14%-55.78%
EPS (TTM)$-0.75$-2.18
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$11.46$13.15
52-week low$1.07$3.99
Distance from 52-week high-59.50%-65.32%
Analyst consensusstrong_buynone
Avg. price target upside+111.21%+393.42%
Average volume1.48M1.85M
Shares outstanding96.72M99.45M
Employees58195
SectorHealthcareHealth Care
IndustryBiotechnologyBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • The two companies sit in different sectors: Rezolute in Healthcare and ARS Pharmaceuticals in Health Care.

About Rezolute

RZLT stock →

Rezolute, Inc., a late-stage rare disease company, focuses developing therapies that treat refractory and debilitating hypoglycemia associated with various forms of hyperinsulinism (HI) in the United States. Its lead clinical asset is ersodetug, an intravenously administered human monoclonal antibody which is in Phase 3 clinical trial to treat tumor HI indication, as well as congenital HI.

Healthcare · Biotechnology · 58 employees

About ARS Pharmaceuticals

SPRY stock →

ARS Pharmaceuticals, Inc., a biopharmaceutical company, develops and commercializes treatments for severe allergic reactions in the United States and internationally. The company is involved in the development of neffy, a needle-free intranasal delivery of epinephrine for emergency treatment of Type I allergic reactions, including anaphylaxis.

Health Care · Biotechnology: Pharmaceutical Preparations · 195 employees

RZLT vs SPRY FAQ

Which is bigger, Rezolute or ARS Pharmaceuticals?

ARS Pharmaceuticals (SPRY) is larger, with a market capitalization of $453.48M compared with $448.79M for Rezolute (RZLT).

Which stock has performed better over the past year, RZLT or SPRY?

RZLT returned -50.00% over the past 12 months, compared with -58.96% for SPRY (price return, excluding dividends). Past performance does not predict future results.

Are Rezolute and ARS Pharmaceuticals in the same industry?

No. Rezolute is in the Healthcare sector, while ARS Pharmaceuticals is in Health Care.

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