Bio-Techne (TECH) vs Twist Bioscience (TWST)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Twist Bioscience (TWST) has outperformed Bio-Techne (TECH) over the past year, gaining 400.2% versus a gain of 22.5%. Over five years, TWST leads with a +38.0% price change compared with -41.7% for TECH. Bio-Techne is the larger company by market cap ($11.37 billion vs $10.32 billion), about 1.1 times the size, while Twist Bioscience is growing revenue faster (+20.3% vs -0.4%).
Bio-Techne pays a dividend yielding 0.44%, while Twist Bioscience does not currently pay one. Bio-Techne converts more of its revenue into profit, with a net margin of 15.0% versus -20.6%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | TECH | TWST |
|---|---|---|
| Share price | $72.53 | $155.65 |
| Market cap | $11.37B | $10.32B |
| 1-day change | +0.14% | -6.78% |
| YTD return | +23.33% | +390.70% |
| 1-year return | +22.54% | +400.16% |
| 5-year return | -41.75% | +37.99% |
| P/E ratio (TTM) | 62.53 | — |
| Forward P/E | 31.36 | — |
| EPS (TTM) | $1.16 | $-2.42 |
| Dividend yield | 0.44% | 0.00% |
| Annual dividend | $0.32 | $0.00 |
| Revenue (latest FY) | $1.22B | $376.57M |
| Revenue growth (YoY) | -0.38% | +20.32% |
| Net income (latest FY) | $181.86M | $-77.67M |
| Gross margin | 65.77% | 50.72% |
| Operating margin | 20.73% | -36.18% |
| Net margin | 14.97% | -20.63% |
| 52-week high | $72.69 | $219.71 |
| 52-week low | $43.20 | $23.30 |
| Distance from 52-week high | -0.22% | -29.16% |
| Analyst consensus | hold | buy |
| Avg. price target upside | -2.80% | -14.07% |
| Average volume | 3.08M | 1.93M |
| Shares outstanding | 156.82M | 66.30M |
| Employees | 3,000 | 979 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Biological Products (No Diagnostic Substances) | Biotechnology: Biological Products (No Diagnostic Substances) |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- TWST has outperformed TECH by 377.6 percentage points over the past year.
- Bio-Techne is more profitable, keeping 15.0 cents of every revenue dollar as net income versus -20.6 cents for Twist Bioscience.
- Twist Bioscience grew revenue faster in its latest fiscal year (+20.32% vs -0.38%).
About Bio-Techne
TECH stock →Bio-Techne Corporation, together with its subsidiaries, develops, manufactures, and sells life science reagents, instruments, and services for the research, diagnostics, and bioprocessing markets worldwide. It operates through two segments, Protein Sciences, and Diagnostics and Spatial Biology.
Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 3,000 employees
About Twist Bioscience
TWST stock →Twist Bioscience Corporation manufactures and sells synthetic DNA-based products. It offers synthetic genes and gene fragments used in product development for therapeutics, diagnostics, chemicals/materials, food/agriculture, data storage, and various applications within academic research by biotech, pharma, industrial chemical, and agricultural companies, as well as academic labs; Oligo pools used in targeted NGS, CRISPR gene editing, mutagenesis experiments, DNA origami, DNA computing, data storage in DNA, and other applications; and immunoglobulin G proteins for customers focused on the pursuit of drug discovery and development.
Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 979 employees
TECH vs TWST FAQ
Which is bigger, Bio-Techne or Twist Bioscience?
Bio-Techne (TECH) is larger, with a market capitalization of $11.37B compared with $10.32B for Twist Bioscience (TWST).
Which stock has performed better over the past year, TECH or TWST?
TWST returned +400.16% over the past 12 months, compared with +22.54% for TECH (price return, excluding dividends). Past performance does not predict future results.
Which pays a higher dividend, Bio-Techne or Twist Bioscience?
Bio-Techne pays a dividend yielding 0.44%, while Twist Bioscience does not currently pay a regular dividend.
Are Bio-Techne and Twist Bioscience in the same industry?
Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.