Qiagen N.V. (QGEN) vs Twist Bioscience (TWST)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Twist Bioscience (TWST) has outperformed Qiagen N.V. (QGEN) over the past year, gaining 400.2% versus a loss of 4.3%. Over five years, TWST leads with a +38.0% price change compared with -16.0% for QGEN. Twist Bioscience is the larger company by market cap ($10.08 billion vs $9.20 billion), about 1.1 times the size.
Qiagen N.V. pays a dividend yielding 0.82%, while Twist Bioscience does not currently pay one. Qiagen N.V. converts more of its revenue into profit, with a net margin of 20.3% versus -20.6%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | QGEN | TWST |
|---|---|---|
| Share price | $44.53 | $152.05 |
| Market cap | $9.20B | $10.08B |
| 1-day change | -0.58% | -2.31% |
| YTD return | -0.40% | +390.70% |
| 1-year return | -4.29% | +400.16% |
| 5-year return | -15.95% | +37.99% |
| P/E ratio (TTM) | 22.60 | — |
| Forward P/E | 17.04 | — |
| EPS (TTM) | $1.97 | $-2.23 |
| Dividend yield | 0.82% | 0.00% |
| Annual dividend | $0.363 | $0.00 |
| Revenue (latest FY) | $2.09B | $376.57M |
| Revenue growth (YoY) | +5.65% | +20.32% |
| Net income (latest FY) | $424.88M | $-77.67M |
| Gross margin | 62.18% | 50.72% |
| Operating margin | 22.29% | -36.18% |
| Net margin | 20.33% | -20.63% |
| 52-week high | $57.82 | $219.71 |
| 52-week low | $32.53 | $23.30 |
| Distance from 52-week high | -22.99% | -30.80% |
| Analyst consensus | buy | buy |
| Avg. price target upside | +6.15% | -12.04% |
| Average volume | 2.75M | 1.99M |
| Shares outstanding | 206.50M | 66.30M |
| Employees | 5,500 | 979 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Biological Products (No Diagnostic Substances) | Biotechnology: Biological Products (No Diagnostic Substances) |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- TWST has outperformed QGEN by 404.5 percentage points over the past year.
- Qiagen N.V. is more profitable, keeping 20.3 cents of every revenue dollar as net income versus -20.6 cents for Twist Bioscience.
- Twist Bioscience grew revenue faster in its latest fiscal year (+20.32% vs +5.65%).
About Qiagen N.V.
QGEN stock →Qiagen N.V. provides sample to insight solutions that transform biological samples into molecular insights worldwide.
Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 5,500 employees
About Twist Bioscience
TWST stock →Twist Bioscience Corporation manufactures and sells synthetic DNA-based products. It offers synthetic genes and gene fragments used in product development for therapeutics, diagnostics, chemicals/materials, food/agriculture, data storage, and various applications within academic research by biotech, pharma, industrial chemical, and agricultural companies, as well as academic labs; Oligo pools used in targeted NGS, CRISPR gene editing, mutagenesis experiments, DNA origami, DNA computing, data storage in DNA, and other applications; and immunoglobulin G proteins for customers focused on the pursuit of drug discovery and development.
Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 979 employees
QGEN vs TWST FAQ
Which is bigger, Qiagen N.V. or Twist Bioscience?
Twist Bioscience (TWST) is larger, with a market capitalization of $10.08B compared with $9.20B for Qiagen N.V. (QGEN).
Which stock has performed better over the past year, QGEN or TWST?
TWST returned +400.16% over the past 12 months, compared with -4.29% for QGEN (price return, excluding dividends). Past performance does not predict future results.
Which pays a higher dividend, Qiagen N.V. or Twist Bioscience?
Qiagen N.V. pays a dividend yielding 0.82%, while Twist Bioscience does not currently pay a regular dividend.
Are Qiagen N.V. and Twist Bioscience in the same industry?
Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.