MetaCap

Upstream Bio (UPB) vs Vogenx (VOGX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Vogenx is the larger company by market cap ($263.6 million vs $249.8 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

UPB-33.29%VOGX+24.31%
+172%+64%-43%
Aug 12, 20261 yearOct 7, 2026
UPB-34.79%VOGX+9.34%
+138%+47%-43%
Aug 10, 20265 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

UPB versus VOGX key metrics
MetricUPBVOGX
Share price$4.56$17.75
Market cap$249.76M$263.60M
1-day change-1.08%+9.81%
YTD return-83.02%—
1-year return-75.31%—
EPS (TTM)$-2.88$-0.22
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$33.68$38.41
52-week low$4.37$12.95
Distance from 52-week high-86.46%-53.80%
Analyst consensusnonestrong_buy
Avg. price target upside+582.89%+209.95%
Average volume610.08K188.79K
Shares outstanding54.77M14.86M
Employees754
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Upstream Bio

UPB stock →

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. It offers verekitug, which is in Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease and in Phase I clinical trial for treating chronic obstructive pulmonary disease.

Health Care · Biotechnology: Pharmaceutical Preparations · 75 employees

About Vogenx

VOGX stock →

Vogenx, Inc. operates as a clinical-stage drug development company that develops therapeutics for metabolic including post-bariatric hypoglycemia, or PBH, and gastroparesis.

Health Care · Biotechnology: Pharmaceutical Preparations · 4 employees

UPB vs VOGX FAQ

Which is bigger, Upstream Bio or Vogenx?

Vogenx (VOGX) is larger, with a market capitalization of $263.60M compared with $249.76M for Upstream Bio (UPB).

Are Upstream Bio and Vogenx in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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