Caribou Biosciences Stock Price History
NASDAQ: CRBUHealth CareBiotechnology: Biological Products (No Diagnostic Substances)USD
At close: Oct 9, 4:00 PM ET · Delayed 15 min
CRBU price history at a glance
The price history for Caribou Biosciences (CRBU) on this page begins on July 19, 2021, when the stock closed at $16.32; it most recently closed at $0.4602 on October 5, 2026. The highest price in this record is $32.65, reached on September 6, 2021; the latest close is 98.6% below that peak. Across the 4 complete calendar years in the table, CRBU finished higher in 0 and lower in 4. Its best year was 2025 (-7.6%) and its worst was 2024 (-70.0%).
Over roughly 5 years the share price changed -97.2%, a -49.6% compound annual price return (excluding dividends). In the last 12 months alone, CRBU has lost 83.3%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2021
- $32.65
- Date of high
- Sep 6, 2021
- Low since 2021
- $0.4425
- Date of low
- Oct 5, 2026
- 52-week high
- $3.54
- 52-week low
- $0.4425
- IPO year
- 2021
- Last close
- $0.4602
CRBU returns
1 week
-62.28%
1 month
-68.04%
3 months
-76.09%
6 months
-76.16%
Year to date
-71.06%
1 year
-83.27%
3 years
-89.02%
5 years
-97.79%
CRBU price return, excluding dividends.
CRBU annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 0.4602 | -71.06% |
| 2025 | 1.59 | -7.56% |
| 2024 | 1.72 | -69.98% |
| 2023 | 5.73 | -8.76% |
| 2022 | 6.28 | -58.38% |
| 2021* | 15.09 | -7.54% |
* Partial year: the record begins after the start of 2021; return measured from the first available close.
2026 return is year to date.
CRBU daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 0.46 | 0.5194 | 0.4425 | 0.4602 | -4.36% | |
| 0.588 | 0.5968 | 0.4503 | 0.4812 | -22.06% | |
| 0.62 | 0.67 | 0.546 | 0.6174 | -45.60% | |
| 1.19 | 1.22 | 1.13 | 1.14 | -4.62% | |
| 1.22 | 1.24 | 1.17 | 1.19 | -2.46% | |
| 1.24 | 1.24 | 1.22 | 1.22 | 0.00% | |
| 1.27 | 1.29 | 1.22 | 1.22 | -3.94% | |
| 1.28 | 1.29 | 1.25 | 1.27 | +2.42% | |
| 1.25 | 1.27 | 1.22 | 1.24 | +0.81% | |
| 1.25 | 1.26 | 1.22 | 1.23 | -0.81% | |
| 1.25 | 1.27 | 1.22 | 1.24 | -0.80% | |
| 1.29 | 1.29 | 1.25 | 1.25 | -3.10% | |
| 1.34 | 1.36 | 1.29 | 1.29 | -3.73% | |
| 1.32 | 1.36 | 1.31 | 1.34 | +3.08% | |
| 1.31 | 1.35 | 1.29 | 1.30 | 0.00% | |
| 1.33 | 1.34 | 1.30 | 1.30 | -0.76% | |
| 1.27 | 1.33 | 1.26 | 1.31 | +4.80% | |
| 1.28 | 1.29 | 1.25 | 1.25 | -1.57% | |
| 1.31 | 1.31 | 1.25 | 1.27 | -1.55% | |
| 1.28 | 1.33 | 1.25 | 1.29 | +1.57% | |
| 1.38 | 1.40 | 1.26 | 1.27 | -7.30% | |
| 1.43 | 1.44 | 1.35 | 1.37 | -4.86% | |
| 1.54 | 1.54 | 1.44 | 1.44 | -6.49% | |
| 1.57 | 1.58 | 1.54 | 1.54 | -1.91% | |
| 1.57 | 1.60 | 1.55 | 1.57 | 0.00% | |
| 1.61 | 1.61 | 1.53 | 1.57 | -1.88% | |
| 1.55 | 1.63 | 1.55 | 1.60 | +3.23% | |
| 1.53 | 1.59 | 1.52 | 1.55 | +0.65% | |
| 1.61 | 1.63 | 1.53 | 1.54 | -4.94% | |
| 1.66 | 1.67 | 1.60 | 1.62 | -2.41% | |
| 1.67 | 1.69 | 1.64 | 1.66 | +0.61% | |
| 1.75 | 1.75 | 1.64 | 1.65 | -6.25% | |
| 1.65 | 1.76 | 1.65 | 1.76 | +7.32% | |
| 1.68 | 1.69 | 1.61 | 1.64 | -1.20% | |
| 1.64 | 1.69 | 1.62 | 1.66 | +3.11% | |
| 1.64 | 1.65 | 1.58 | 1.61 | -1.83% | |
| 1.60 | 1.66 | 1.58 | 1.64 | +5.13% | |
| 1.56 | 1.58 | 1.53 | 1.56 | -0.64% | |
| 1.57 | 1.59 | 1.55 | 1.57 | -0.63% | |
| 1.61 | 1.61 | 1.52 | 1.58 | -1.86% | |
| 1.72 | 1.72 | 1.60 | 1.61 | -5.29% | |
| 1.69 | 1.71 | 1.66 | 1.70 | +0.59% | |
| 1.68 | 1.71 | 1.65 | 1.69 | +1.81% | |
| 1.65 | 1.68 | 1.63 | 1.66 | +0.61% | |
| 1.65 | 1.67 | 1.63 | 1.65 | +0.61% | |
| 1.61 | 1.68 | 1.59 | 1.64 | +1.86% | |
| 1.59 | 1.66 | 1.58 | 1.61 | +2.55% | |
| 1.50 | 1.58 | 1.50 | 1.57 | +4.67% | |
| 1.47 | 1.50 | 1.43 | 1.50 | +2.74% | |
| 1.53 | 1.53 | 1.43 | 1.46 | -3.31% | |
| 1.48 | 1.53 | 1.45 | 1.51 | +2.72% | |
| 1.50 | 1.51 | 1.44 | 1.47 | -1.34% | |
| 1.60 | 1.60 | 1.47 | 1.49 | -6.29% | |
| 1.60 | 1.65 | 1.58 | 1.59 | +1.27% | |
| 1.62 | 1.64 | 1.57 | 1.57 | -3.68% | |
| 1.62 | 1.65 | 1.60 | 1.63 | -1.81% | |
| 1.65 | 1.67 | 1.63 | 1.66 | +0.61% | |
| 1.61 | 1.73 | 1.59 | 1.65 | +1.85% | |
| 1.64 | 1.67 | 1.59 | 1.62 | -1.82% | |
| 1.62 | 1.69 | 1.60 | 1.65 | -0.60% | |
| 1.70 | 1.72 | 1.64 | 1.66 | -4.05% | |
| 1.76 | 1.77 | 1.71 | 1.73 | -1.14% | |
| 1.82 | 1.84 | 1.75 | 1.75 | -2.78% | |
| 1.91 | 1.91 | 1.76 | 1.80 | -6.49% | |
| 1.92 | 1.93 | 1.76 | 1.93 | -0.77% | |
| 1.93 | 1.99 | 1.84 | 1.94 | 0.00% | |
| 1.88 | 2.11 | 1.85 | 1.94 | +1.04% | |
| 1.84 | 1.93 | 1.75 | 1.92 | +4.92% | |
| 1.83 | 1.85 | 1.80 | 1.83 | +0.55% | |
| 1.77 | 1.92 | 1.77 | 1.82 | +3.41% | |
| 1.76 | 1.79 | 1.73 | 1.76 | 0.00% | |
| 1.81 | 1.82 | 1.73 | 1.76 | -0.56% | |
| 1.70 | 1.83 | 1.67 | 1.77 | +5.36% | |
| 1.57 | 1.73 | 1.56 | 1.68 | +7.01% | |
| 1.68 | 1.69 | 1.56 | 1.57 | -5.42% | |
| 1.67 | 1.71 | 1.63 | 1.66 | 0.00% | |
| 1.62 | 1.72 | 1.62 | 1.66 | +1.22% | |
| 1.63 | 1.70 | 1.62 | 1.64 | 0.00% | |
| 1.66 | 1.70 | 1.57 | 1.64 | 0.00% | |
| 1.66 | 1.78 | 1.63 | 1.64 | -2.96% | |
| 1.66 | 1.73 | 1.63 | 1.69 | +1.81% | |
| 1.61 | 1.69 | 1.61 | 1.66 | +4.08% | |
| 1.74 | 1.77 | 1.59 | 1.60 | -3.92% | |
| 1.80 | 1.83 | 1.61 | 1.66 | -7.26% | |
| 1.83 | 1.88 | 1.77 | 1.79 | -2.72% | |
| 1.85 | 1.92 | 1.78 | 1.84 | 0.00% | |
| 1.97 | 1.97 | 1.83 | 1.84 | -4.17% | |
| 2.06 | 2.06 | 1.91 | 1.92 | -7.02% | |
| 2.01 | 2.15 | 2.01 | 2.07 | +3.25% | |
| 2.29 | 2.30 | 2.00 | 2.00 | -13.79% | |
| 2.45 | 2.45 | 2.29 | 2.32 | -4.53% | |
| 2.36 | 2.49 | 2.31 | 2.43 | +2.97% | |
| 2.33 | 2.40 | 2.27 | 2.36 | +2.16% | |
| 2.30 | 2.37 | 2.25 | 2.31 | 0.00% | |
| 2.18 | 2.41 | 2.14 | 2.31 | +6.94% | |
| 2.10 | 2.25 | 2.09 | 2.16 | +2.86% | |
| 2.00 | 2.12 | 1.97 | 2.10 | +5.53% | |
| 1.95 | 2.02 | 1.88 | 1.99 | -0.50% | |
| 1.98 | 2.04 | 1.97 | 2.00 | +1.52% | |
| 2.05 | 2.11 | 1.95 | 1.97 | -4.83% | |
| 2.16 | 2.28 | 1.98 | 2.07 | -3.27% | |
| 2.13 | 2.19 | 2.09 | 2.14 | 0.00% | |
| 2.13 | 2.32 | 1.99 | 2.14 | +0.94% | |
| 2.03 | 2.15 | 2.00 | 2.12 | +4.43% | |
| 2.04 | 2.08 | 1.97 | 2.03 | 0.00% | |
| 1.97 | 2.19 | 1.96 | 2.03 | +4.64% | |
| 1.90 | 1.99 | 1.89 | 1.94 | +3.19% | |
| 1.95 | 1.96 | 1.85 | 1.88 | -3.59% | |
| 1.95 | 1.97 | 1.93 | 1.95 | +1.04% | |
| 1.95 | 1.99 | 1.89 | 1.93 | +1.05% | |
| 1.85 | 1.97 | 1.85 | 1.91 | +2.14% | |
| 1.91 | 1.91 | 1.83 | 1.87 | -0.53% | |
| 1.93 | 1.96 | 1.84 | 1.88 | -2.08% | |
| 2.08 | 2.08 | 1.91 | 1.92 | -7.69% | |
| 2.12 | 2.16 | 2.06 | 2.08 | -2.35% | |
| 2.18 | 2.26 | 2.10 | 2.13 | 0.00% | |
| 2.26 | 2.27 | 2.11 | 2.13 | -5.75% | |
| 2.33 | 2.39 | 2.24 | 2.26 | -4.24% | |
| 2.29 | 2.39 | 2.26 | 2.36 | +4.89% | |
| 2.30 | 2.33 | 2.23 | 2.25 | -1.75% | |
| 2.21 | 2.32 | 2.18 | 2.29 | +4.09% | |
| 2.22 | 2.26 | 2.14 | 2.20 | +2.33% | |
| 2.21 | 2.22 | 2.10 | 2.15 | -2.27% | |
| 2.14 | 2.22 | 2.13 | 2.20 | +3.77% | |
| 1.97 | 2.17 | 1.97 | 2.12 | +8.72% | |
| 1.91 | 1.99 | 1.90 | 1.95 | +1.04% | |
| 1.96 | 1.98 | 1.90 | 1.93 | -1.53% | |
| 1.95 | 2.00 | 1.93 | 1.96 | +0.51% | |
| 1.95 | 2.00 | 1.91 | 1.95 | +4.84% | |
| 1.94 | 1.94 | 1.84 | 1.86 | -4.62% | |
| 1.95 | 2.01 | 1.92 | 1.95 | +0.52% | |
| 1.91 | 2.01 | 1.89 | 1.94 | -2.51% | |
| 1.92 | 2.04 | 1.92 | 1.99 | +4.74% | |
| 1.80 | 2.01 | 1.80 | 1.90 | +10.47% | |
| 1.79 | 1.81 | 1.69 | 1.72 | -3.37% | |
| 1.88 | 1.91 | 1.76 | 1.78 | -6.81% | |
| 1.84 | 2.01 | 1.84 | 1.91 | +1.60% | |
| 1.85 | 1.96 | 1.85 | 1.88 | +3.30% | |
| 1.84 | 1.88 | 1.76 | 1.82 | -2.15% | |
| 1.89 | 1.92 | 1.82 | 1.86 | -0.53% | |
| 1.96 | 1.97 | 1.85 | 1.87 | -5.08% | |
| 1.87 | 1.98 | 1.83 | 1.97 | +3.14% | |
| 1.96 | 2.01 | 1.89 | 1.91 | -3.05% | |
| 1.88 | 1.97 | 1.86 | 1.97 | +5.35% | |
| 1.89 | 2.00 | 1.86 | 1.87 | -0.53% | |
| 1.92 | 1.93 | 1.84 | 1.88 | -0.53% | |
| 1.93 | 1.95 | 1.86 | 1.89 | -4.06% | |
| 2.00 | 2.02 | 1.93 | 1.97 | -2.96% | |
| 2.00 | 2.06 | 1.96 | 2.03 | +3.05% | |
| 1.79 | 2.00 | 1.79 | 1.97 | +8.24% | |
| 1.66 | 1.83 | 1.66 | 1.82 | +6.43% | |
| 1.79 | 1.82 | 1.67 | 1.71 | -5.00% | |
| 1.78 | 1.86 | 1.74 | 1.80 | +2.27% | |
| 1.80 | 1.81 | 1.73 | 1.76 | -4.35% | |
| 1.78 | 1.89 | 1.76 | 1.84 | -3.16% | |
| 1.95 | 2.01 | 1.89 | 1.90 | -4.52% | |
| 1.93 | 2.02 | 1.87 | 1.99 | +2.05% | |
| 2.15 | 2.18 | 1.92 | 1.95 | -8.88% | |
| 1.90 | 2.22 | 1.87 | 2.14 | +11.46% | |
| 1.80 | 1.93 | 1.78 | 1.92 | +6.67% | |
| 1.75 | 1.85 | 1.71 | 1.80 | +2.27% | |
| 1.61 | 1.77 | 1.58 | 1.76 | +8.64% | |
| 1.55 | 1.62 | 1.53 | 1.62 | +4.52% | |
| 1.57 | 1.58 | 1.51 | 1.55 | -1.90% | |
| 1.52 | 1.64 | 1.52 | 1.58 | +3.95% | |
| 1.59 | 1.59 | 1.47 | 1.52 | -4.40% | |
| 1.58 | 1.60 | 1.48 | 1.59 | +1.27% | |
| 1.63 | 1.63 | 1.57 | 1.57 | -3.68% | |
| 1.58 | 1.65 | 1.53 | 1.63 | +3.82% | |
| 1.52 | 1.58 | 1.50 | 1.57 | +6.08% | |
| 1.60 | 1.65 | 1.45 | 1.48 | -8.64% | |
| 1.59 | 1.64 | 1.49 | 1.62 | +3.85% | |
| 1.56 | 1.74 | 1.48 | 1.56 | +6.85% | |
| 1.40 | 1.48 | 1.38 | 1.46 | +3.55% | |
| 1.46 | 1.47 | 1.39 | 1.41 | -4.73% | |
| 1.53 | 1.53 | 1.47 | 1.48 | -2.63% | |
| 1.56 | 1.56 | 1.49 | 1.52 | -1.94% | |
| 1.53 | 1.58 | 1.52 | 1.55 | +1.31% | |
| 1.52 | 1.53 | 1.47 | 1.53 | 0.00% | |
| 1.61 | 1.63 | 1.53 | 1.53 | -5.56% | |
| 1.50 | 1.65 | 1.48 | 1.62 | +8.72% | |
| 1.40 | 1.50 | 1.40 | 1.49 | +7.19% | |
| 1.44 | 1.45 | 1.39 | 1.39 | -4.79% | |
| 1.55 | 1.57 | 1.45 | 1.46 | -6.41% | |
| 1.62 | 1.63 | 1.55 | 1.56 | -3.11% | |
| 1.60 | 1.62 | 1.58 | 1.61 | +1.26% | |
| 1.60 | 1.64 | 1.56 | 1.59 | +0.63% | |
| 1.64 | 1.65 | 1.52 | 1.58 | -4.82% | |
| 1.72 | 1.73 | 1.64 | 1.66 | -1.78% | |
| 1.76 | 1.77 | 1.68 | 1.69 | -4.52% | |
| 1.72 | 1.80 | 1.70 | 1.77 | +2.91% | |
| 1.62 | 1.72 | 1.61 | 1.72 | +6.83% | |
| 1.59 | 1.62 | 1.54 | 1.61 | +1.26% | |
| 1.59 | 1.60 | 1.54 | 1.59 | 0.00% | |
| 1.57 | 1.61 | 1.56 | 1.59 | 0.00% | |
| 1.64 | 1.65 | 1.58 | 1.59 | -3.64% | |
| 1.69 | 1.71 | 1.64 | 1.65 | -2.94% | |
| 1.70 | 1.72 | 1.65 | 1.70 | -1.16% | |
| 1.65 | 1.73 | 1.64 | 1.72 | +3.61% | |
| 1.72 | 1.72 | 1.63 | 1.66 | -3.49% | |
| 1.70 | 1.74 | 1.67 | 1.72 | +2.38% | |
| 1.64 | 1.70 | 1.62 | 1.68 | +3.07% | |
| 1.63 | 1.75 | 1.62 | 1.63 | +0.62% | |
| 1.69 | 1.73 | 1.62 | 1.62 | -4.14% | |
| 1.72 | 1.74 | 1.65 | 1.69 | -1.17% | |
| 1.84 | 1.85 | 1.71 | 1.71 | -4.47% | |
| 1.86 | 1.88 | 1.79 | 1.79 | -3.76% | |
| 1.88 | 1.90 | 1.82 | 1.86 | -2.11% | |
| 1.87 | 1.91 | 1.82 | 1.90 | +1.60% | |
| 1.90 | 1.90 | 1.84 | 1.87 | -1.06% | |
| 1.92 | 1.96 | 1.86 | 1.89 | -0.53% | |
| 1.93 | 1.95 | 1.86 | 1.90 | -2.06% | |
| 1.87 | 1.97 | 1.84 | 1.94 | +4.30% | |
| 1.76 | 1.87 | 1.76 | 1.86 | +5.68% | |
| 1.78 | 1.83 | 1.75 | 1.76 | -0.56% | |
| 1.89 | 1.89 | 1.76 | 1.77 | -8.76% | |
| 1.90 | 1.97 | 1.87 | 1.94 | +3.19% | |
| 1.86 | 1.90 | 1.80 | 1.88 | +0.53% | |
| 1.87 | 1.89 | 1.76 | 1.87 | 0.00% | |
| 1.76 | 1.87 | 1.75 | 1.87 | +6.86% | |
| 1.74 | 1.86 | 1.73 | 1.75 | 0.00% | |
| 1.84 | 1.92 | 1.72 | 1.75 | -3.85% | |
| 1.85 | 1.89 | 1.81 | 1.82 | -2.67% | |
| 1.87 | 1.92 | 1.83 | 1.87 | -1.06% | |
| 1.98 | 2.01 | 1.85 | 1.89 | -5.03% | |
| 1.94 | 2.07 | 1.92 | 1.99 | +0.25% | |
| 2.30 | 2.30 | 1.96 | 1.99 | -12.17% | |
| 2.24 | 2.27 | 2.11 | 2.26 | +0.89% | |
| 2.05 | 2.26 | 2.04 | 2.24 | +8.21% | |
| 2.14 | 2.26 | 2.01 | 2.07 | -0.96% | |
| 2.02 | 2.12 | 1.93 | 2.09 | -2.34% | |
| 2.25 | 2.26 | 2.08 | 2.14 | -2.28% | |
| 2.28 | 2.29 | 2.09 | 2.19 | +0.92% | |
| 2.40 | 2.47 | 2.13 | 2.17 | -10.70% | |
| 3.40 | 3.54 | 2.38 | 2.43 | +0.41% | |
| 2.31 | 2.47 | 2.28 | 2.42 | +4.31% | |
| 2.35 | 2.44 | 2.32 | 2.32 | -2.11% | |
| 2.48 | 2.49 | 2.36 | 2.37 | -4.05% | |
| 2.46 | 2.59 | 2.40 | 2.47 | +0.82% | |
| 2.51 | 2.52 | 2.35 | 2.45 | -1.61% | |
| 2.57 | 2.60 | 2.45 | 2.49 | -0.40% | |
| 2.52 | 2.59 | 2.47 | 2.50 | -1.19% | |
| 2.83 | 2.85 | 2.44 | 2.53 | -10.92% | |
| 2.83 | 2.97 | 2.75 | 2.84 | +0.71% | |
| 2.70 | 2.93 | 2.68 | 2.82 | +7.22% | |
| 2.63 | 2.70 | 2.58 | 2.63 | -1.50% | |
| 2.83 | 2.94 | 2.64 | 2.67 | -5.99% | |
| 2.47 | 2.84 | 2.43 | 2.84 | +16.39% | |
| 2.33 | 2.51 | 2.27 | 2.44 | +2.52% | |
| 2.55 | 2.60 | 2.37 | 2.38 | -4.42% | |
| 2.76 | 2.77 | 2.43 | 2.49 | -9.45% | |
| 2.76 | 2.87 | 2.70 | 2.75 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the CRBU chart for longer ranges.