Structure Therapeutics Stock Price History
NASDAQ: GPCRHealth CareBiotechnology: Pharmaceutical PreparationsUSD
25.54-0.13 (-0.51%)
At close: Oct 9, 4:00 PM ET · Delayed 15 min
GPCR price history at a glance
The price history for Structure Therapeutics (GPCR) on this page begins on January 30, 2023, when the stock closed at $26.00; it most recently closed at $25.54 on October 5, 2026. The highest price in this record is $94.90, reached on December 8, 2025; the latest close is 73.1% below that peak. Over roughly 4 years the share price changed -1.8%, a -0.5% compound annual price return (excluding dividends).
In the last 12 months alone, GPCR has lost 16.4%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2023
- $94.90
- Date of high
- Dec 8, 2025
- Low since 2023
- $13.22
- Date of low
- Apr 7, 2025
- 52-week high
- $94.90
- 52-week low
- $25.09
- IPO year
- 2023
- Last close
- $25.54
GPCR returns
1 week
-7.70%
1 month
-38.05%
3 months
-52.14%
6 months
-53.15%
Year to date
-63.28%
1 year
-16.40%
3 years
-60.74%
GPCR price return, excluding dividends.
GPCR annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 25.54 | -62.51% |
| 2025 | 68.12 | +145.39% |
| 2024 | 27.76 | -31.89% |
| 2023* | 40.76 | +56.77% |
* Partial year: the record begins after the start of 2023; return measured from the first available close.
2026 return is year to date.
GPCR daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 25.73 | 26.15 | 25.30 | 25.54 | -0.51% | |
| 26.57 | 26.80 | 25.09 | 25.67 | -3.79% | |
| 27.14 | 28.05 | 26.38 | 26.68 | -2.88% | |
| 27.55 | 27.85 | 26.69 | 27.47 | -0.43% | |
| 28.10 | 28.21 | 26.41 | 27.59 | -0.29% | |
| 28.99 | 29.25 | 27.57 | 27.67 | -4.52% | |
| 31.27 | 31.39 | 28.93 | 28.98 | -7.32% | |
| 33.05 | 33.05 | 31.08 | 31.27 | -4.34% | |
| 34.78 | 34.93 | 32.44 | 32.69 | -6.77% | |
| 34.86 | 35.64 | 34.43 | 35.07 | -2.41% | |
| 36.29 | 37.20 | 35.50 | 35.93 | -0.25% | |
| 35.35 | 36.27 | 34.43 | 36.02 | +0.19% | |
| 36.50 | 37.30 | 34.96 | 35.95 | -2.60% | |
| 36.99 | 37.74 | 36.25 | 36.91 | +0.27% | |
| 35.34 | 36.99 | 35.00 | 36.81 | +5.17% | |
| 35.04 | 35.63 | 34.42 | 35.00 | -0.28% | |
| 36.05 | 36.45 | 35.05 | 35.10 | -1.13% | |
| 39.19 | 39.19 | 35.42 | 35.50 | -8.86% | |
| 38.36 | 39.03 | 37.75 | 38.95 | +1.33% | |
| 38.92 | 39.24 | 37.82 | 38.44 | -0.57% | |
| 39.82 | 40.27 | 38.10 | 38.66 | -2.25% | |
| 40.51 | 40.90 | 39.29 | 39.55 | -4.07% | |
| 41.23 | 44.94 | 40.49 | 41.23 | +2.11% | |
| 46.84 | 47.38 | 40.26 | 40.38 | -14.70% | |
| 47.26 | 48.06 | 46.73 | 47.34 | 0.00% | |
| 48.21 | 48.25 | 46.37 | 47.34 | -0.96% | |
| 47.76 | 48.64 | 46.07 | 47.80 | +1.42% | |
| 46.02 | 48.03 | 45.58 | 47.13 | +2.66% | |
| 47.08 | 47.38 | 45.10 | 45.91 | -3.08% | |
| 48.93 | 49.20 | 46.96 | 47.37 | -3.76% | |
| 49.61 | 49.81 | 48.50 | 49.22 | -0.26% | |
| 49.75 | 50.07 | 48.45 | 49.35 | -1.14% | |
| 49.65 | 51.02 | 49.37 | 49.92 | +1.86% | |
| 48.61 | 49.33 | 47.62 | 49.01 | -0.16% | |
| 50.70 | 51.11 | 49.01 | 49.09 | -2.83% | |
| 54.15 | 54.60 | 50.33 | 50.52 | -6.67% | |
| 54.30 | 55.35 | 52.40 | 54.13 | +1.12% | |
| 53.70 | 55.60 | 52.58 | 53.53 | -0.43% | |
| 54.00 | 54.66 | 53.00 | 53.76 | -1.38% | |
| 54.61 | 54.99 | 52.81 | 54.51 | -0.35% | |
| 53.91 | 55.00 | 52.57 | 54.70 | +1.47% | |
| 52.55 | 53.92 | 51.00 | 53.91 | +3.41% | |
| 53.70 | 53.70 | 51.88 | 52.13 | -3.11% | |
| 53.19 | 53.87 | 51.87 | 53.81 | +1.25% | |
| 53.80 | 54.80 | 50.83 | 53.14 | +0.99% | |
| 50.02 | 52.78 | 50.02 | 52.62 | +4.14% | |
| 49.98 | 51.67 | 49.85 | 50.53 | +1.79% | |
| 49.40 | 50.51 | 48.30 | 49.64 | +2.65% | |
| 48.04 | 48.71 | 46.58 | 48.36 | +0.67% | |
| 49.50 | 49.50 | 46.81 | 48.04 | -2.89% | |
| 47.29 | 49.62 | 46.40 | 49.47 | +4.48% | |
| 47.10 | 48.69 | 47.00 | 47.35 | -1.13% | |
| 48.41 | 48.41 | 46.79 | 47.89 | -1.64% | |
| 49.35 | 51.30 | 48.69 | 48.69 | -0.88% | |
| 50.76 | 51.00 | 49.04 | 49.12 | -3.31% | |
| 50.43 | 52.60 | 49.99 | 50.80 | +0.77% | |
| 48.80 | 50.48 | 48.80 | 50.41 | +2.15% | |
| 46.91 | 49.42 | 46.06 | 49.35 | +5.04% | |
| 48.48 | 49.46 | 46.21 | 46.98 | -3.09% | |
| 45.65 | 49.65 | 44.80 | 48.48 | +5.32% | |
| 49.46 | 49.46 | 45.97 | 46.03 | -7.23% | |
| 50.08 | 50.31 | 48.10 | 49.62 | -1.92% | |
| 51.60 | 52.35 | 50.22 | 50.59 | -2.03% | |
| 52.75 | 53.00 | 50.50 | 51.64 | -3.22% | |
| 54.98 | 54.99 | 52.45 | 53.36 | -3.23% | |
| 54.08 | 55.48 | 54.00 | 55.14 | +0.46% | |
| 55.76 | 56.34 | 52.90 | 54.89 | -3.07% | |
| 55.12 | 57.07 | 54.15 | 56.63 | +3.43% | |
| 53.20 | 55.10 | 52.56 | 54.75 | +2.43% | |
| 51.43 | 54.24 | 51.02 | 53.45 | +2.55% | |
| 53.93 | 54.66 | 51.25 | 52.12 | -2.89% | |
| 51.69 | 55.00 | 51.69 | 53.67 | +3.83% | |
| 49.71 | 51.86 | 49.11 | 51.69 | +3.98% | |
| 48.47 | 50.29 | 48.19 | 49.71 | +3.03% | |
| 48.19 | 49.94 | 48.17 | 48.25 | +0.19% | |
| 45.68 | 48.24 | 45.36 | 48.16 | +5.59% | |
| 44.93 | 46.29 | 43.99 | 45.61 | +0.22% | |
| 44.51 | 46.78 | 44.44 | 45.51 | +2.25% | |
| 45.94 | 47.24 | 44.35 | 44.51 | -1.09% | |
| 42.79 | 45.75 | 42.79 | 45.00 | +4.87% | |
| 42.71 | 43.09 | 41.71 | 42.91 | -0.37% | |
| 43.00 | 43.50 | 42.47 | 43.07 | +0.33% | |
| 42.50 | 43.50 | 42.01 | 42.93 | -0.85% | |
| 40.91 | 43.36 | 40.33 | 43.30 | +4.26% | |
| 40.03 | 43.45 | 40.01 | 41.53 | +0.68% | |
| 40.00 | 41.80 | 39.10 | 41.25 | +9.21% | |
| 37.47 | 38.68 | 36.45 | 37.77 | +0.51% | |
| 38.71 | 39.82 | 37.39 | 37.58 | -3.79% | |
| 37.90 | 39.71 | 37.90 | 39.06 | +4.16% | |
| 37.40 | 38.04 | 36.53 | 37.50 | +0.83% | |
| 37.99 | 38.65 | 36.75 | 37.19 | -3.53% | |
| 39.34 | 39.74 | 37.80 | 38.55 | -2.01% | |
| 41.18 | 41.18 | 39.06 | 39.34 | -2.07% | |
| 40.00 | 40.57 | 39.49 | 40.17 | +1.59% | |
| 39.84 | 41.50 | 39.27 | 39.54 | -0.10% | |
| 39.19 | 39.63 | 38.05 | 39.58 | +1.00% | |
| 39.20 | 40.38 | 38.70 | 39.19 | +1.03% | |
| 37.10 | 38.89 | 36.51 | 38.79 | +5.21% | |
| 36.05 | 37.94 | 35.86 | 36.87 | +2.76% | |
| 36.25 | 37.09 | 35.79 | 35.88 | -0.64% | |
| 38.63 | 38.63 | 35.78 | 36.11 | -6.67% | |
| 39.01 | 39.80 | 38.27 | 38.69 | -2.89% | |
| 38.00 | 40.00 | 36.93 | 39.84 | +4.62% | |
| 37.69 | 38.19 | 36.92 | 38.08 | +0.63% | |
| 38.23 | 38.90 | 37.43 | 37.84 | -1.25% | |
| 39.01 | 40.14 | 37.92 | 38.32 | -1.99% | |
| 38.16 | 39.93 | 37.69 | 39.10 | -0.13% | |
| 40.62 | 40.75 | 38.88 | 39.15 | -4.14% | |
| 40.76 | 42.31 | 40.63 | 40.84 | -0.63% | |
| 43.16 | 44.78 | 40.83 | 41.10 | -4.51% | |
| 42.15 | 43.71 | 41.82 | 43.04 | +1.97% | |
| 43.93 | 44.66 | 41.94 | 42.21 | +1.83% | |
| 41.32 | 42.17 | 40.81 | 41.45 | +0.21% | |
| 43.31 | 44.00 | 40.68 | 41.37 | -5.04% | |
| 45.03 | 47.32 | 43.21 | 43.56 | -3.90% | |
| 45.79 | 47.49 | 45.16 | 45.33 | -0.35% | |
| 47.00 | 47.30 | 45.06 | 45.49 | -3.25% | |
| 46.50 | 48.03 | 45.78 | 47.02 | +1.12% | |
| 47.30 | 47.99 | 46.05 | 46.50 | -0.70% | |
| 48.06 | 48.62 | 45.76 | 46.83 | -2.88% | |
| 50.05 | 50.70 | 48.00 | 48.22 | -4.99% | |
| 54.77 | 54.77 | 50.55 | 50.75 | -5.14% | |
| 54.63 | 55.54 | 53.08 | 53.50 | -1.38% | |
| 52.74 | 54.42 | 51.21 | 54.25 | +1.94% | |
| 55.32 | 56.14 | 53.00 | 53.22 | -1.90% | |
| 53.50 | 56.40 | 53.10 | 54.25 | -0.48% | |
| 55.11 | 55.70 | 52.63 | 54.51 | -1.14% | |
| 52.25 | 55.84 | 52.25 | 55.14 | +3.82% | |
| 57.00 | 57.23 | 52.87 | 53.11 | -2.87% | |
| 51.03 | 54.85 | 50.23 | 54.68 | +5.62% | |
| 53.48 | 54.49 | 50.84 | 51.77 | -3.20% | |
| 48.29 | 55.75 | 48.00 | 53.48 | +6.60% | |
| 49.46 | 52.47 | 48.84 | 50.17 | +4.09% | |
| 44.92 | 48.35 | 44.45 | 48.20 | +9.70% | |
| 45.66 | 45.80 | 42.72 | 43.94 | -4.31% | |
| 46.10 | 46.54 | 44.77 | 45.92 | -0.61% | |
| 47.42 | 48.28 | 46.00 | 46.20 | -4.01% | |
| 48.83 | 49.20 | 47.99 | 48.13 | +2.32% | |
| 48.27 | 48.67 | 46.75 | 47.04 | -4.12% | |
| 49.42 | 51.39 | 48.37 | 49.06 | +0.97% | |
| 50.07 | 50.40 | 47.71 | 48.59 | -3.71% | |
| 50.08 | 51.61 | 49.37 | 50.46 | -2.76% | |
| 55.47 | 55.47 | 51.14 | 51.89 | -7.59% | |
| 56.06 | 57.47 | 53.60 | 56.15 | -0.88% | |
| 56.58 | 61.20 | 53.06 | 56.65 | +5.40% | |
| 55.00 | 56.00 | 52.51 | 53.75 | -1.52% | |
| 57.46 | 57.65 | 54.58 | 54.58 | -6.22% | |
| 58.22 | 59.55 | 57.33 | 58.20 | -0.03% | |
| 56.95 | 60.61 | 56.95 | 58.22 | +3.04% | |
| 56.85 | 58.88 | 55.00 | 56.50 | -2.13% | |
| 57.90 | 59.31 | 57.02 | 57.73 | -3.30% | |
| 62.75 | 62.99 | 58.28 | 59.70 | -5.43% | |
| 63.23 | 64.99 | 62.50 | 63.13 | +0.15% | |
| 62.19 | 64.64 | 59.56 | 63.04 | +0.21% | |
| 61.88 | 64.37 | 61.51 | 62.90 | -0.13% | |
| 64.13 | 65.05 | 62.17 | 62.98 | -2.73% | |
| 66.24 | 66.25 | 63.07 | 64.75 | -2.68% | |
| 69.00 | 69.00 | 66.40 | 66.53 | -3.45% | |
| 67.12 | 68.96 | 64.84 | 68.91 | +2.67% | |
| 67.78 | 68.26 | 66.16 | 67.12 | +0.86% | |
| 67.11 | 68.14 | 65.58 | 66.55 | -1.36% | |
| 68.23 | 68.23 | 64.96 | 67.47 | -1.30% | |
| 71.23 | 71.70 | 68.20 | 68.36 | -4.27% | |
| 69.61 | 72.31 | 68.65 | 71.41 | +1.91% | |
| 72.10 | 73.33 | 69.95 | 70.07 | -2.73% | |
| 75.82 | 77.35 | 71.81 | 72.04 | -5.19% | |
| 78.65 | 79.10 | 74.34 | 75.98 | -3.27% | |
| 76.82 | 81.15 | 76.82 | 78.55 | -0.48% | |
| 75.20 | 79.45 | 74.93 | 78.93 | +5.35% | |
| 75.50 | 76.13 | 72.27 | 74.92 | +2.34% | |
| 79.31 | 79.39 | 72.10 | 73.21 | -9.91% | |
| 83.97 | 84.80 | 78.99 | 81.26 | -3.01% | |
| 88.97 | 89.94 | 82.27 | 83.78 | -6.75% | |
| 87.58 | 92.06 | 87.55 | 89.84 | +1.57% | |
| 87.15 | 90.24 | 86.67 | 88.45 | +1.49% | |
| 88.48 | 89.39 | 86.10 | 87.15 | -2.13% | |
| 89.01 | 90.00 | 87.35 | 89.05 | -0.51% | |
| 88.89 | 91.21 | 88.02 | 89.51 | -0.07% | |
| 89.60 | 91.21 | 87.00 | 89.57 | -0.89% | |
| 92.00 | 92.00 | 88.70 | 90.37 | -1.63% | |
| 93.79 | 94.32 | 90.24 | 91.87 | -2.05% | |
| 93.28 | 94.42 | 90.22 | 93.79 | +3.04% | |
| 88.36 | 94.77 | 86.75 | 91.02 | +2.69% | |
| 89.83 | 92.85 | 84.71 | 88.64 | +4.26% | |
| 83.66 | 85.39 | 80.85 | 85.02 | +0.82% | |
| 78.12 | 85.20 | 77.69 | 84.33 | +8.23% | |
| 69.00 | 83.22 | 69.00 | 77.92 | +12.34% | |
| 68.93 | 70.39 | 68.50 | 69.36 | +1.09% | |
| 66.64 | 69.78 | 66.59 | 68.61 | +2.43% | |
| 65.91 | 67.51 | 65.48 | 66.98 | +1.10% | |
| 63.67 | 67.55 | 63.45 | 66.25 | +4.76% | |
| 63.40 | 68.09 | 62.01 | 63.24 | +0.75% | |
| 68.15 | 68.25 | 61.99 | 62.77 | -7.85% | |
| 69.77 | 70.40 | 65.60 | 68.12 | -2.06% | |
| 67.70 | 69.63 | 67.34 | 69.55 | +2.61% | |
| 67.23 | 68.88 | 66.80 | 67.78 | +0.59% | |
| 68.00 | 68.92 | 66.58 | 67.38 | -1.40% | |
| 69.69 | 69.69 | 67.25 | 68.34 | -1.94% | |
| 71.00 | 72.00 | 68.66 | 69.69 | -2.24% | |
| 63.21 | 71.75 | 63.21 | 71.29 | +12.71% | |
| 64.91 | 65.77 | 61.87 | 63.25 | -2.60% | |
| 66.03 | 69.30 | 64.30 | 64.94 | +3.99% | |
| 60.25 | 62.95 | 59.58 | 62.45 | +4.14% | |
| 61.50 | 62.49 | 59.92 | 59.97 | -2.82% | |
| 63.32 | 64.03 | 58.84 | 61.71 | -4.77% | |
| 67.08 | 68.56 | 64.36 | 64.80 | -3.37% | |
| 68.61 | 68.91 | 65.81 | 67.06 | -0.56% | |
| 69.30 | 72.39 | 66.90 | 67.44 | -2.18% | |
| 67.04 | 71.50 | 65.02 | 68.94 | +3.30% | |
| 67.87 | 71.99 | 66.15 | 66.74 | -4.63% | |
| 45.33 | 94.90 | 44.74 | 69.98 | +102.49% | |
| 33.13 | 35.81 | 32.51 | 34.56 | +5.21% | |
| 31.61 | 33.55 | 30.94 | 32.85 | +3.89% | |
| 32.23 | 32.71 | 31.42 | 31.62 | -1.56% | |
| 34.10 | 35.15 | 31.98 | 32.12 | -7.09% | |
| 35.26 | 36.09 | 34.23 | 34.57 | -3.46% | |
| 34.50 | 35.86 | 34.15 | 35.81 | +4.65% | |
| 34.55 | 35.32 | 33.55 | 34.22 | +0.15% | |
| 35.41 | 35.41 | 33.95 | 34.17 | -3.20% | |
| 34.06 | 35.62 | 33.36 | 35.30 | +2.86% | |
| 34.34 | 35.28 | 33.81 | 34.32 | -0.06% | |
| 36.50 | 37.44 | 34.10 | 34.34 | -5.94% | |
| 34.85 | 40.29 | 34.73 | 36.51 | +5.83% | |
| 36.90 | 37.80 | 34.37 | 34.50 | -7.85% | |
| 36.77 | 38.05 | 36.12 | 37.44 | +1.68% | |
| 35.00 | 37.60 | 34.82 | 36.82 | +5.20% | |
| 35.65 | 36.49 | 34.66 | 35.00 | -2.56% | |
| 34.86 | 36.00 | 34.50 | 35.92 | +3.03% | |
| 34.00 | 35.16 | 34.00 | 34.87 | +2.85% | |
| 33.72 | 35.13 | 33.00 | 33.90 | +3.23% | |
| 33.70 | 33.89 | 30.95 | 32.84 | -1.88% | |
| 32.55 | 33.86 | 32.43 | 33.47 | +3.91% | |
| 34.01 | 34.01 | 31.50 | 32.21 | -5.29% | |
| 33.01 | 34.50 | 32.64 | 34.01 | +3.82% | |
| 33.10 | 33.37 | 31.77 | 32.76 | -1.68% | |
| 32.57 | 34.10 | 32.11 | 33.32 | +3.41% | |
| 30.52 | 32.35 | 30.24 | 32.22 | +8.96% | |
| 28.94 | 29.80 | 28.45 | 29.57 | +2.14% | |
| 28.98 | 29.40 | 28.22 | 28.95 | +1.05% | |
| 26.74 | 28.82 | 26.62 | 28.65 | +8.56% | |
| 26.60 | 26.78 | 25.94 | 26.39 | -0.64% | |
| 26.85 | 27.49 | 25.86 | 26.56 | -0.38% | |
| 26.76 | 27.00 | 25.59 | 26.66 | -0.97% | |
| 27.87 | 28.24 | 26.67 | 26.92 | -3.41% | |
| 27.87 | 28.26 | 27.40 | 27.87 | +1.79% | |
| 27.06 | 28.56 | 27.00 | 27.38 | -0.65% | |
| 29.37 | 29.66 | 27.49 | 27.56 | -5.71% | |
| 30.38 | 31.08 | 29.21 | 29.23 | -2.99% | |
| 29.98 | 30.97 | 29.49 | 30.13 | -0.20% | |
| 30.15 | 30.66 | 29.46 | 30.19 | +0.40% | |
| 30.77 | 30.93 | 29.38 | 30.07 | -1.57% | |
| 28.54 | 30.90 | 28.33 | 30.55 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the GPCR chart for longer ranges.