Krystal Biotech Stock Price History
NASDAQ: KRYSHealth CareBiotechnology: Biological Products (No Diagnostic Substances)USD
331.61+4.31 (+1.32%)
At close: Oct 9, 4:00 PM ET · Delayed 15 min
KRYS price history at a glance
The price history for Krystal Biotech (KRYS) on this page begins on September 18, 2017, when the stock closed at $10.06; it most recently closed at $331.61 on October 5, 2026. The highest price in this record is $382.54, reached on June 29, 2026; the latest close is 13.3% below that peak. Across the 8 complete calendar years in the table, KRYS finished higher in 8 and lower in 0. Its best year was 2018 (+141.2%) and its worst was 2020 (+0.6%).
Over roughly 9 years the share price changed +3196.3%, a 47.2% compound annual price return (excluding dividends). In the last 12 months alone, KRYS has gained 82.7%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2017
- $382.54
- Date of high
- Jun 29, 2026
- Low since 2017
- $8.03
- Date of low
- Dec 18, 2017
- 52-week high
- $382.54
- 52-week low
- $179.19
- IPO year
- 2017
- Last close
- $331.61
KRYS returns
1 week
+2.89%
1 month
-4.73%
3 months
-9.35%
6 months
+28.03%
Year to date
+34.51%
1 year
+82.74%
3 years
+191.45%
5 years
+580.64%
KRYS price return, excluding dividends.
KRYS annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 331.61 | +34.30% |
| 2025 | 246.91 | +55.95% |
| 2024 | 158.33 | +27.62% |
| 2023 | 124.06 | +56.60% |
| 2022 | 79.22 | +13.25% |
| 2021 | 69.95 | +16.58% |
| 2020 | 60.00 | +0.59% |
| 2019 | 59.65 | +135.12% |
| 2018 | 25.37 | +141.16% |
| 2017* | 10.52 | +4.57% |
* Partial year: the record begins after the start of 2017; return measured from the first available close.
2026 return is year to date.
KRYS daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 326.55 | 333.44 | 323.87 | 331.61 | +1.32% | |
| 321.61 | 332.11 | 319.58 | 327.30 | +0.84% | |
| 324.87 | 330.44 | 320.20 | 324.57 | -0.69% | |
| 335.16 | 335.16 | 319.61 | 326.81 | -2.40% | |
| 323.76 | 339.69 | 321.37 | 334.85 | +3.90% | |
| 326.75 | 329.22 | 320.29 | 322.28 | -0.93% | |
| 332.51 | 334.52 | 325.22 | 325.31 | -2.18% | |
| 336.56 | 337.03 | 331.80 | 332.56 | -0.75% | |
| 334.62 | 338.48 | 331.78 | 335.06 | -0.60% | |
| 347.00 | 350.00 | 334.01 | 337.08 | -2.53% | |
| 346.34 | 347.74 | 341.90 | 345.82 | +0.25% | |
| 341.85 | 345.48 | 336.56 | 344.96 | +0.94% | |
| 353.84 | 353.84 | 337.58 | 341.75 | -2.60% | |
| 334.76 | 353.83 | 334.31 | 350.88 | +5.10% | |
| 339.48 | 341.15 | 332.44 | 333.85 | -0.84% | |
| 340.00 | 341.35 | 335.50 | 336.67 | -0.61% | |
| 340.99 | 343.33 | 335.50 | 338.75 | +0.62% | |
| 337.53 | 346.20 | 334.73 | 336.67 | -0.00% | |
| 339.01 | 340.09 | 331.80 | 336.68 | -0.99% | |
| 349.14 | 352.55 | 339.25 | 340.03 | -2.01% | |
| 349.59 | 354.24 | 346.68 | 347.00 | +0.42% | |
| 347.56 | 349.66 | 344.26 | 345.55 | -0.73% | |
| 348.85 | 353.12 | 340.18 | 348.09 | -0.90% | |
| 350.49 | 354.69 | 343.46 | 351.26 | -1.95% | |
| 365.45 | 371.99 | 353.75 | 358.24 | -3.56% | |
| 371.41 | 373.31 | 365.56 | 371.47 | +0.61% | |
| 366.00 | 373.19 | 360.86 | 369.23 | +1.48% | |
| 360.00 | 364.44 | 358.38 | 363.84 | +1.25% | |
| 348.62 | 363.52 | 345.14 | 359.36 | +2.25% | |
| 356.92 | 356.92 | 348.57 | 351.46 | -1.68% | |
| 357.61 | 362.50 | 355.09 | 357.46 | -0.64% | |
| 354.37 | 363.82 | 350.43 | 359.76 | +1.00% | |
| 343.81 | 357.91 | 343.81 | 356.19 | +4.23% | |
| 343.51 | 346.55 | 337.09 | 341.72 | -1.40% | |
| 337.44 | 348.03 | 335.72 | 346.58 | +2.84% | |
| 338.32 | 343.14 | 334.99 | 337.02 | -1.84% | |
| 339.61 | 345.56 | 335.44 | 343.34 | +3.16% | |
| 332.18 | 337.41 | 330.31 | 332.82 | -0.87% | |
| 330.31 | 337.21 | 330.06 | 335.73 | +1.04% | |
| 333.85 | 333.85 | 320.62 | 332.27 | +1.20% | |
| 332.99 | 334.88 | 327.28 | 328.34 | -1.36% | |
| 326.95 | 334.21 | 325.00 | 332.86 | +1.78% | |
| 333.30 | 336.28 | 324.32 | 327.05 | -1.37% | |
| 324.54 | 332.73 | 324.54 | 331.59 | +1.57% | |
| 326.34 | 329.00 | 320.34 | 326.45 | +1.17% | |
| 323.46 | 329.52 | 320.94 | 322.69 | -0.95% | |
| 326.86 | 331.07 | 316.15 | 325.78 | +0.31% | |
| 314.73 | 328.83 | 313.76 | 324.77 | +3.90% | |
| 320.70 | 332.31 | 297.02 | 312.57 | -8.37% | |
| 364.66 | 367.30 | 340.55 | 341.12 | -7.01% | |
| 368.26 | 368.70 | 360.07 | 366.85 | +0.98% | |
| 361.91 | 369.00 | 357.77 | 363.28 | -0.26% | |
| 355.76 | 364.95 | 350.10 | 364.23 | +3.53% | |
| 339.00 | 358.00 | 334.38 | 351.82 | +4.96% | |
| 327.55 | 338.58 | 326.01 | 335.19 | +2.35% | |
| 333.25 | 336.49 | 326.08 | 327.50 | -2.76% | |
| 337.32 | 341.67 | 332.01 | 336.80 | -0.67% | |
| 336.72 | 341.97 | 325.00 | 339.06 | -0.05% | |
| 355.60 | 360.98 | 338.85 | 339.22 | -4.41% | |
| 338.96 | 355.85 | 335.00 | 354.86 | +3.82% | |
| 347.56 | 351.21 | 337.03 | 341.79 | -2.41% | |
| 332.89 | 351.69 | 327.97 | 350.24 | +3.18% | |
| 365.04 | 365.04 | 330.00 | 339.43 | -6.61% | |
| 361.94 | 367.79 | 353.49 | 363.44 | -0.65% | |
| 375.00 | 375.00 | 355.55 | 365.81 | -1.46% | |
| 376.12 | 382.13 | 365.09 | 371.24 | -1.11% | |
| 368.60 | 375.51 | 364.52 | 375.40 | +1.84% | |
| 374.49 | 377.24 | 366.52 | 368.60 | -1.62% | |
| 373.66 | 377.00 | 368.87 | 374.68 | -0.10% | |
| 374.57 | 377.35 | 365.28 | 375.07 | +0.94% | |
| 370.57 | 377.31 | 363.28 | 371.58 | -0.02% | |
| 377.00 | 382.54 | 368.24 | 371.67 | -1.71% | |
| 367.70 | 378.44 | 365.93 | 378.15 | +1.58% | |
| 360.45 | 376.28 | 359.38 | 372.25 | +3.42% | |
| 347.27 | 362.40 | 347.21 | 359.93 | +3.54% | |
| 343.59 | 353.89 | 343.59 | 347.63 | +2.18% | |
| 339.21 | 346.82 | 337.60 | 340.21 | -0.94% | |
| 356.49 | 356.49 | 341.66 | 343.43 | -1.33% | |
| 350.00 | 356.50 | 343.48 | 348.06 | +1.87% | |
| 323.55 | 347.67 | 322.95 | 341.66 | +5.66% | |
| 326.54 | 329.98 | 321.11 | 323.37 | -0.42% | |
| 318.00 | 326.12 | 314.00 | 324.75 | +2.13% | |
| 331.49 | 331.49 | 316.54 | 317.97 | -1.11% | |
| 314.12 | 326.47 | 312.25 | 321.55 | +2.92% | |
| 309.75 | 320.32 | 309.45 | 312.41 | +0.86% | |
| 306.99 | 311.00 | 302.29 | 309.75 | +2.65% | |
| 302.47 | 306.18 | 300.00 | 301.76 | +0.25% | |
| 305.34 | 312.81 | 300.02 | 301.00 | -2.21% | |
| 300.75 | 312.38 | 298.93 | 307.79 | +1.98% | |
| 292.23 | 304.90 | 290.04 | 301.82 | +2.94% | |
| 294.37 | 297.00 | 285.07 | 293.21 | -1.64% | |
| 309.03 | 309.03 | 298.00 | 298.10 | -3.54% | |
| 311.70 | 315.58 | 307.09 | 309.03 | -0.41% | |
| 306.00 | 311.07 | 299.28 | 310.30 | +1.20% | |
| 304.67 | 308.73 | 302.00 | 306.63 | +1.31% | |
| 302.03 | 303.87 | 298.99 | 302.68 | +1.08% | |
| 305.10 | 309.41 | 297.18 | 299.45 | -1.57% | |
| 300.97 | 306.45 | 296.20 | 304.23 | +0.72% | |
| 297.09 | 303.37 | 296.13 | 302.05 | +2.98% | |
| 289.78 | 296.05 | 286.00 | 293.30 | +0.53% | |
| 308.00 | 308.99 | 289.39 | 291.75 | -4.75% | |
| 312.29 | 314.05 | 305.99 | 306.29 | -3.16% | |
| 316.79 | 319.48 | 312.00 | 316.30 | +1.19% | |
| 309.53 | 317.21 | 302.87 | 312.58 | +0.73% | |
| 313.33 | 315.17 | 308.30 | 310.31 | -0.82% | |
| 308.38 | 315.17 | 306.84 | 312.88 | +2.35% | |
| 297.00 | 306.10 | 292.00 | 305.71 | +3.04% | |
| 288.99 | 297.48 | 279.74 | 296.70 | +2.67% | |
| 286.28 | 290.00 | 280.10 | 288.99 | +1.55% | |
| 291.12 | 303.00 | 283.50 | 284.57 | -0.83% | |
| 265.60 | 287.64 | 251.97 | 286.95 | +7.86% | |
| 263.13 | 266.38 | 256.92 | 266.04 | +1.44% | |
| 260.78 | 262.97 | 257.79 | 262.26 | +0.89% | |
| 265.82 | 270.44 | 257.53 | 259.95 | -3.46% | |
| 273.87 | 276.95 | 268.68 | 269.27 | -1.28% | |
| 272.01 | 281.65 | 267.94 | 272.75 | +0.08% | |
| 267.34 | 274.99 | 259.70 | 272.52 | +1.67% | |
| 276.23 | 278.75 | 266.64 | 268.04 | -2.86% | |
| 275.17 | 278.06 | 271.31 | 275.94 | +1.20% | |
| 277.47 | 277.47 | 271.62 | 272.66 | -1.39% | |
| 274.37 | 278.86 | 272.00 | 276.50 | +0.84% | |
| 268.88 | 276.24 | 267.31 | 274.21 | +3.84% | |
| 266.92 | 267.41 | 262.02 | 264.06 | -1.67% | |
| 270.01 | 271.05 | 262.40 | 268.54 | -0.54% | |
| 267.86 | 275.75 | 267.86 | 270.00 | +0.97% | |
| 259.12 | 268.10 | 256.56 | 267.41 | +3.25% | |
| 258.87 | 259.89 | 255.61 | 259.00 | +0.26% | |
| 262.46 | 262.86 | 252.30 | 258.33 | -2.23% | |
| 267.42 | 272.12 | 262.27 | 264.22 | +0.09% | |
| 261.21 | 264.80 | 257.09 | 263.99 | +0.84% | |
| 260.95 | 266.63 | 260.53 | 261.80 | +0.33% | |
| 252.62 | 260.99 | 252.62 | 260.95 | +0.79% | |
| 260.97 | 264.00 | 255.48 | 258.91 | +0.23% | |
| 252.00 | 260.81 | 242.00 | 258.32 | +4.61% | |
| 247.58 | 249.46 | 242.48 | 246.94 | +0.63% | |
| 248.11 | 249.60 | 242.26 | 245.39 | -2.39% | |
| 249.06 | 259.14 | 249.00 | 251.40 | -1.39% | |
| 251.04 | 257.65 | 250.91 | 254.95 | +3.18% | |
| 248.70 | 252.83 | 243.18 | 247.09 | -1.20% | |
| 254.25 | 255.99 | 247.37 | 250.08 | -0.64% | |
| 258.91 | 263.75 | 249.38 | 251.68 | -2.45% | |
| 250.83 | 258.34 | 249.10 | 258.00 | +2.86% | |
| 256.08 | 257.58 | 250.30 | 250.83 | -2.15% | |
| 251.89 | 259.27 | 249.74 | 256.33 | +2.47% | |
| 251.78 | 255.05 | 246.00 | 250.16 | +1.17% | |
| 254.75 | 257.36 | 246.76 | 247.26 | -1.61% | |
| 251.01 | 253.59 | 244.50 | 251.31 | -1.45% | |
| 257.64 | 258.63 | 254.31 | 255.00 | -2.33% | |
| 258.98 | 265.65 | 256.71 | 261.08 | +0.94% | |
| 254.30 | 260.56 | 251.78 | 258.65 | +1.96% | |
| 255.00 | 260.00 | 251.18 | 253.69 | -2.55% | |
| 260.28 | 263.30 | 254.12 | 260.33 | -1.76% | |
| 266.93 | 266.99 | 257.44 | 265.00 | +0.45% | |
| 253.70 | 268.26 | 253.70 | 263.80 | +1.93% | |
| 267.60 | 270.00 | 258.78 | 258.81 | -6.11% | |
| 275.69 | 276.99 | 272.69 | 275.64 | -0.26% | |
| 272.88 | 277.03 | 266.96 | 276.36 | +1.42% | |
| 266.90 | 275.00 | 266.90 | 272.50 | +2.10% | |
| 274.59 | 275.00 | 262.33 | 266.90 | -2.80% | |
| 261.84 | 275.14 | 260.73 | 274.59 | +4.89% | |
| 261.51 | 264.03 | 252.61 | 261.80 | -0.33% | |
| 280.00 | 281.69 | 259.58 | 262.67 | -7.28% | |
| 286.67 | 290.31 | 277.77 | 283.29 | -1.58% | |
| 289.00 | 298.30 | 270.71 | 287.84 | +4.12% | |
| 271.27 | 280.54 | 271.27 | 276.45 | +2.29% | |
| 275.56 | 275.56 | 269.41 | 270.26 | -0.88% | |
| 271.43 | 274.30 | 264.85 | 272.65 | +0.72% | |
| 273.38 | 274.92 | 270.10 | 270.70 | -0.70% | |
| 276.66 | 280.00 | 270.00 | 272.61 | -0.05% | |
| 276.89 | 277.11 | 260.03 | 272.74 | +1.91% | |
| 265.43 | 274.06 | 265.29 | 267.64 | -0.55% | |
| 281.32 | 282.34 | 258.34 | 269.13 | -3.73% | |
| 282.27 | 286.52 | 273.23 | 279.57 | -0.96% | |
| 276.58 | 285.97 | 276.05 | 282.27 | +1.09% | |
| 282.00 | 282.47 | 274.89 | 279.24 | -0.04% | |
| 273.03 | 283.61 | 273.03 | 279.34 | +2.36% | |
| 278.19 | 279.62 | 272.15 | 272.91 | -1.60% | |
| 278.75 | 281.28 | 275.07 | 277.36 | -0.50% | |
| 279.47 | 281.00 | 275.00 | 278.75 | -0.99% | |
| 289.98 | 294.64 | 280.63 | 281.53 | -2.63% | |
| 286.20 | 292.49 | 286.20 | 289.13 | +1.09% | |
| 274.58 | 286.28 | 271.70 | 286.00 | +4.07% | |
| 280.02 | 282.20 | 271.52 | 274.81 | -3.59% | |
| 284.17 | 289.78 | 282.00 | 285.04 | +1.07% | |
| 295.00 | 295.00 | 279.56 | 282.01 | -3.35% | |
| 292.40 | 295.98 | 287.57 | 291.79 | -0.05% | |
| 273.92 | 292.90 | 266.66 | 291.93 | +7.28% | |
| 260.64 | 274.40 | 257.00 | 272.13 | +4.10% | |
| 254.51 | 267.48 | 252.92 | 261.41 | +5.02% | |
| 249.51 | 255.07 | 245.99 | 248.91 | +1.03% | |
| 250.45 | 254.50 | 245.68 | 246.37 | -1.21% | |
| 250.44 | 257.95 | 246.24 | 249.39 | +1.91% | |
| 246.55 | 247.00 | 235.61 | 244.71 | -0.89% | |
| 245.64 | 246.94 | 238.52 | 246.91 | +0.15% | |
| 247.69 | 250.09 | 245.89 | 246.54 | -0.54% | |
| 253.00 | 256.00 | 246.90 | 247.88 | -2.29% | |
| 251.39 | 265.92 | 248.48 | 253.68 | +0.60% | |
| 251.63 | 252.55 | 249.00 | 252.17 | +0.35% | |
| 253.67 | 253.90 | 249.73 | 251.29 | -0.82% | |
| 249.27 | 255.00 | 248.90 | 253.36 | +1.50% | |
| 241.43 | 249.78 | 241.43 | 249.61 | +3.66% | |
| 233.25 | 245.30 | 231.91 | 240.80 | +3.18% | |
| 238.81 | 239.52 | 231.69 | 233.37 | -1.03% | |
| 237.76 | 238.66 | 234.17 | 235.80 | -1.15% | |
| 240.55 | 243.66 | 238.53 | 238.55 | -1.82% | |
| 244.34 | 247.40 | 240.49 | 242.98 | -0.68% | |
| 246.97 | 248.60 | 242.58 | 244.65 | -0.86% | |
| 239.16 | 246.97 | 239.16 | 246.78 | +2.94% | |
| 234.43 | 241.85 | 234.43 | 239.72 | +2.17% | |
| 232.07 | 237.20 | 231.51 | 234.64 | +0.25% | |
| 237.35 | 241.65 | 227.86 | 234.05 | -0.03% | |
| 222.24 | 234.65 | 220.79 | 234.13 | +5.48% | |
| 215.80 | 222.66 | 213.83 | 221.96 | +2.07% | |
| 215.69 | 219.85 | 214.03 | 217.46 | +1.12% | |
| 216.38 | 219.54 | 212.75 | 215.06 | -0.02% | |
| 216.10 | 216.56 | 212.83 | 215.11 | -1.33% | |
| 219.85 | 219.85 | 215.12 | 218.00 | -0.32% | |
| 216.97 | 221.84 | 213.24 | 218.70 | +0.80% | |
| 216.09 | 220.00 | 214.67 | 216.97 | +0.97% | |
| 212.02 | 219.69 | 212.02 | 214.89 | +1.35% | |
| 204.05 | 214.72 | 203.35 | 212.02 | +3.82% | |
| 208.63 | 210.00 | 203.18 | 204.23 | +0.06% | |
| 203.96 | 208.79 | 203.67 | 204.10 | -0.31% | |
| 206.17 | 209.77 | 202.99 | 204.74 | -1.69% | |
| 205.57 | 212.97 | 205.57 | 208.25 | +1.01% | |
| 199.11 | 207.80 | 198.02 | 206.16 | +2.46% | |
| 201.16 | 204.69 | 199.08 | 201.21 | -0.90% | |
| 202.70 | 209.96 | 202.70 | 203.03 | +0.01% | |
| 201.07 | 204.15 | 199.00 | 203.00 | +1.74% | |
| 199.34 | 201.32 | 197.13 | 199.53 | +0.81% | |
| 200.08 | 200.08 | 192.52 | 197.93 | -1.02% | |
| 198.53 | 203.00 | 195.76 | 199.97 | +0.05% | |
| 198.38 | 204.18 | 194.92 | 199.88 | -1.66% | |
| 197.94 | 212.98 | 195.47 | 203.26 | +2.73% | |
| 197.75 | 198.98 | 184.02 | 197.85 | +0.17% | |
| 187.68 | 198.50 | 185.96 | 197.51 | +4.46% | |
| 184.79 | 191.44 | 184.70 | 189.08 | +2.18% | |
| 187.90 | 189.96 | 183.26 | 185.05 | -2.43% | |
| 189.77 | 190.49 | 185.05 | 189.65 | -0.15% | |
| 187.13 | 191.88 | 187.13 | 189.93 | +2.04% | |
| 188.50 | 189.25 | 185.04 | 186.13 | -0.17% | |
| 186.26 | 189.95 | 183.03 | 186.45 | +0.02% | |
| 190.67 | 190.67 | 183.88 | 186.42 | -2.29% | |
| 195.20 | 195.60 | 188.63 | 190.78 | -2.64% | |
| 191.74 | 196.78 | 188.19 | 195.96 | +3.01% | |
| 192.91 | 192.91 | 186.73 | 190.23 | +1.01% | |
| 193.41 | 195.91 | 187.53 | 188.33 | -2.41% | |
| 188.24 | 195.39 | 187.49 | 192.99 | +2.63% | |
| 183.38 | 189.75 | 181.44 | 188.05 | +1.79% | |
| 182.44 | 186.08 | 179.19 | 184.74 | +1.80% | |
| 189.88 | 190.01 | 181.32 | 181.47 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the KRYS chart for longer ranges.