MetaCap

Lexicon Pharmaceuticals Stock Price History

NASDAQ: LXRXHealth CareBiotechnology: Pharmaceutical PreparationsUSD

1.68-0.08 (-4.55%)

At close: Oct 9, 4:00 PM ET · Delayed 15 min

LXRX price history at a glance

The price history for Lexicon Pharmaceuticals (LXRX) on this page begins on April 3, 2000, when the stock closed at $131.25; it most recently closed at $1.68 on October 5, 2026. The highest price in this record is $344.75, reached on July 17, 2000; the latest close is 99.5% below that peak. Across the 25 complete calendar years in the table, LXRX finished higher in 8 and lower in 17. Its best year was 2015 (+106.7%) and its worst was 2002 (-60.5%).

Over roughly 27 years the share price changed -98.7%, a -15.2% compound annual price return (excluding dividends). In the last 12 months alone, LXRX has gained 12.8%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.

Summary generated from market data by MetaCap's automated system. Methodology

Key price levels

High since 2000
$344.75
Date of high
Jul 17, 2000
Low since 2000
$0.28
Date of low
Mar 3, 2025
52-week high
$2.68
52-week low
$1.10
Last close
$1.68

LXRX returns

1 week

-7.69%

1 month

-21.86%

3 months

-24.32%

6 months

-2.33%

Year to date

+46.09%

1 year

+12.75%

3 years

+41.18%

5 years

-72.73%

LXRX price return, excluding dividends.

LXRX annual returns

Calendar-year price returns
YearYear-end closeReturn
20261.68+47.37%
20251.14+44.30%
20240.79-48.37%
20231.53-19.90%
20221.91-51.52%
20213.94+15.20%
20203.42-13.20%
20193.94-45.43%
20187.22-26.92%
20179.88-28.56%
201613.83+3.91%
201513.31+106.68%
20146.44-50.00%
201312.88-20.00%
201216.10+78.29%
20119.03-10.42%
201010.08-15.29%
200911.90+18.06%
200810.08-50.00%
200720.16-20.22%
200625.27-1.10%
200525.55-52.96%
200454.32+28.26%
200342.35+27.10%
200233.32-60.47%
200184.28-27.58%
2000*116.38-11.33%

* Partial year: the record begins after the start of 2000; return measured from the first available close.

2026 return is year to date.

LXRX daily prices (past year)

Daily open, high, low, close and volume
DateOpenHighLowCloseChange
1.751.771.681.68-4.55%
1.751.781.701.760.00%
1.731.771.711.76+0.57%
1.751.781.721.75+0.57%
1.831.831.721.74-4.40%
1.851.871.801.820.00%
1.861.871.811.82-3.19%
1.891.951.841.880.00%
1.921.941.801.88-1.05%
1.882.051.811.90+5.56%
1.871.931.771.80-3.23%
2.052.061.851.86-9.71%
2.172.172.022.06-5.50%
2.052.202.022.18+6.86%
2.052.082.002.04-0.49%
2.042.061.992.05+0.49%
2.052.112.022.04+0.99%
2.012.062.002.02+0.50%
1.982.021.892.01+1.52%
1.972.011.941.98-1.00%
2.052.061.952.00-0.99%
2.112.142.012.02-6.05%
2.212.232.132.15-3.59%
2.222.252.192.23-0.45%
2.252.262.222.24-0.88%
2.252.272.232.26+0.89%
2.212.272.192.24+2.28%
2.242.272.172.19-2.67%
2.272.292.192.25-1.75%
2.302.322.262.29-1.29%
2.302.342.302.32+0.43%
2.322.352.282.31-1.28%
2.352.372.302.34+0.86%
2.322.352.302.32+0.87%
2.192.312.192.30+5.50%
2.402.402.172.18-9.54%
2.462.482.392.41-0.41%
2.332.442.332.42+3.42%
2.312.392.292.34+0.86%
2.322.342.272.32-0.85%
2.372.392.322.34-0.43%
2.412.462.352.35-3.29%
2.422.452.312.43+1.25%
2.452.492.382.40-2.83%
2.442.482.292.47+4.66%
1.962.441.962.36-3.67%
2.522.522.402.45-1.61%
2.332.522.322.49+6.87%
2.292.342.222.33+0.87%
2.322.352.252.31-1.28%
2.322.402.292.34+0.86%
2.382.422.292.32-0.85%
2.242.352.172.34+4.93%
2.302.382.162.23-2.62%
2.302.352.242.29-0.43%
2.212.352.192.30+2.22%
2.362.372.192.25-5.46%
2.332.402.262.38+2.15%
2.412.422.262.33-2.51%
2.222.402.192.39+6.70%
2.202.262.172.24+1.82%
2.112.212.042.20+3.77%
2.202.222.102.12-2.30%
2.202.222.142.17-2.25%
2.252.252.142.22-1.33%
2.282.282.212.25-0.88%
2.342.352.222.27-4.22%
2.322.442.262.37+2.16%
2.302.422.302.320.00%
2.352.442.272.32-0.85%
2.372.442.332.34-2.50%
2.682.682.372.40-9.09%
2.552.672.492.64+3.53%
2.282.552.282.55+11.35%
2.232.382.232.29+3.15%
2.182.272.182.22+2.78%
2.102.242.062.16+0.47%
1.992.151.992.15+6.97%
2.042.101.982.01-1.47%
1.952.091.952.04+4.62%
1.952.031.921.95-0.51%
1.951.981.921.96+2.08%
1.892.031.881.92+1.59%
1.881.951.841.89+0.53%
1.851.911.851.880.00%
1.881.931.841.880.00%
1.931.991.871.88-1.57%
1.901.941.871.91+0.53%
1.841.991.841.90+2.70%
1.841.931.801.85-2.12%
2.092.091.881.89-8.70%
2.172.192.072.07-5.05%
2.202.232.142.18-1.36%
2.172.272.172.21+1.84%
2.052.212.042.17+5.34%
2.212.222.042.06-4.63%
2.232.292.162.16-3.14%
2.112.262.112.23+0.90%
2.132.262.132.21+3.76%
2.112.152.042.13-0.47%
2.222.262.082.14-4.04%
2.292.322.222.23-4.29%
2.442.442.292.33-4.51%
2.412.512.342.44+1.24%
2.312.532.252.41+4.33%
2.012.472.002.31+15.50%
1.692.001.642.00+19.05%
1.651.691.521.68+5.00%
1.661.661.601.60-3.03%
1.601.651.571.65+3.12%
1.631.671.591.60-1.84%
1.591.661.581.63+1.24%
1.581.631.571.61+3.87%
1.661.661.551.55-6.63%
1.691.721.661.66-1.78%
1.681.761.671.69+0.60%
1.671.701.621.680.00%
1.831.861.671.68-7.69%
1.851.911.801.82-0.55%
1.851.891.791.83-0.54%
1.871.881.801.84-1.60%
1.861.951.861.87+1.63%
1.861.891.811.84-1.08%
1.751.861.741.86+6.29%
1.701.791.701.75+2.34%
1.701.741.691.71-0.58%
1.771.801.701.72-2.27%
1.651.841.651.76+5.39%
1.651.701.621.67+4.37%
1.591.651.551.60+0.63%
1.591.641.581.590.00%
1.611.631.581.59-3.05%
1.591.711.551.64+5.13%
1.521.591.521.56+3.31%
1.651.661.491.51-8.48%
1.621.651.601.65+1.23%
1.661.701.581.63-2.98%
1.721.771.651.68-2.33%
1.631.771.631.72+4.88%
1.561.661.561.64+5.13%
1.621.621.521.56-3.70%
1.551.641.541.62+3.85%
1.611.641.551.56-3.70%
1.601.671.581.62+0.62%
1.711.741.611.61-4.73%
1.701.791.661.69-1.74%
1.701.721.661.720.00%
1.661.721.611.72+3.61%
1.721.781.611.66-1.19%
1.691.791.661.68-1.75%
1.641.761.581.71+4.27%
1.541.761.451.64+0.61%
1.631.661.571.63+1.24%
1.511.641.491.61+3.21%
1.421.581.421.56+6.12%
1.501.501.441.47-2.00%
1.481.531.421.500.00%
1.531.561.471.50+1.35%
1.511.621.481.48-1.99%
1.521.571.471.51+2.72%
1.501.511.441.47-3.29%
1.421.521.401.52+15.15%
1.311.371.301.320.00%
1.321.341.291.32+0.76%
1.311.351.281.310.00%
1.361.371.291.31-4.38%
1.301.391.281.37+4.58%
1.231.331.231.31+9.17%
1.231.241.171.20-2.44%
1.201.271.201.23+4.24%
1.331.401.171.18-7.09%
1.291.321.181.27-0.78%
1.251.291.191.28+2.40%
1.151.291.131.25+7.76%
1.291.331.101.16-19.44%
1.531.551.421.44-4.00%
1.711.711.501.50-12.28%
1.571.711.551.71+8.92%
1.711.711.571.57-7.65%
1.781.791.651.70-3.41%
1.551.831.521.76+12.82%
1.341.651.331.56+19.08%
1.331.331.251.31-4.38%
1.281.411.261.37+7.03%
1.241.291.231.28+3.23%
1.211.271.211.24+3.33%
1.191.231.181.20+1.69%
1.151.181.111.18+0.85%
1.181.201.171.17-0.85%
1.151.211.141.18+0.85%
1.141.231.141.17+2.63%
1.161.171.121.140.00%
1.151.171.121.140.00%
1.161.161.111.14-0.87%
1.141.161.121.150.00%
1.161.181.131.15-1.71%
1.201.221.151.17-4.88%
1.231.241.191.230.00%
1.211.241.201.23+1.65%
1.231.241.171.21-0.82%
1.171.321.161.22+4.27%
1.171.201.121.17-0.85%
1.151.251.141.18+2.61%
1.181.221.141.15-4.17%
1.221.251.171.20-2.44%
1.311.331.231.23-5.38%
1.321.351.301.30-1.52%
1.311.361.301.320.00%
1.331.361.301.32+0.76%
1.391.401.291.31-5.76%
1.421.481.351.39-0.71%
1.421.451.381.40-1.41%
1.411.431.381.42+1.43%
1.341.411.341.40+4.48%
1.371.401.341.34-1.47%
1.381.401.351.36-4.90%
1.431.471.401.430.00%
1.411.441.391.43+1.42%
1.441.441.371.41-0.70%
1.351.421.341.42+5.97%
1.321.351.281.34+1.52%
1.441.511.321.32-8.97%
1.481.521.421.45-1.36%
1.451.481.431.47+0.68%
1.471.471.421.46-2.01%
1.381.511.361.49+3.47%
1.511.531.431.44-6.49%
1.561.641.471.54-1.28%
1.391.591.361.56+9.86%
1.251.451.251.42+13.60%
1.391.421.181.25-12.59%
1.401.531.391.43+3.62%
1.331.401.311.38+3.76%
1.331.391.321.33-2.21%
1.381.391.351.36-1.45%
1.351.401.341.38+2.99%
1.341.371.301.34+0.75%
1.371.371.311.33-2.92%
1.391.411.361.37-1.44%
1.451.481.391.39-2.11%
1.421.461.401.42+1.43%
1.401.441.401.40+0.72%
1.441.451.361.39-3.47%
1.521.531.441.44-5.26%
1.441.531.431.52+7.04%
1.441.461.391.42-3.40%
1.541.581.451.47-3.92%
1.491.531.471.53+4.79%
1.441.491.421.46+1.39%
1.511.511.401.44-3.36%
1.661.661.451.49—

Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the LXRX chart for longer ranges.