Lyell Immunopharma Stock Price History
NASDAQ: LYELHealth CareBiotechnology: Pharmaceutical PreparationsUSD
8.71-0.08 (-0.91%)
At close: Oct 9, 4:00 PM ET · Delayed 15 min
LYEL price history at a glance
The price history for Lyell Immunopharma (LYEL) on this page begins on June 14, 2021, when the stock closed at $324.00; it most recently closed at $8.71 on October 5, 2026. The highest price in this record is $396.80, reached on September 6, 2021; the latest close is 97.8% below that peak. Across the 4 complete calendar years in the table, LYEL finished higher in 1 and lower in 3. Its best year was 2025 (+107.6%) and its worst was 2024 (-64.0%).
Over roughly 5 years the share price changed -97.3%, a -49.4% compound annual price return (excluding dividends). In the last 12 months alone, LYEL has lost 53.8%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2021
- $396.80
- Date of high
- Sep 6, 2021
- Low since 2021
- $7.65
- Date of low
- Jun 2, 2025
- 52-week high
- $45.00
- 52-week low
- $8.21
- IPO year
- 2021
- Last close
- $8.71
LYEL returns
1 week
-5.94%
1 month
-32.38%
3 months
-41.97%
6 months
-61.10%
Year to date
-71.70%
1 year
-53.84%
3 years
-73.45%
5 years
-96.72%
LYEL price return, excluding dividends.
LYEL annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 8.71 | -69.94% |
| 2025 | 28.98 | +107.59% |
| 2024 | 13.96 | -64.02% |
| 2023 | 38.80 | -44.09% |
| 2022 | 69.40 | -55.17% |
| 2021* | 154.80 | -52.22% |
* Partial year: the record begins after the start of 2021; return measured from the first available close.
2026 return is year to date.
LYEL daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 8.72 | 9.10 | 8.62 | 8.71 | -0.91% | |
| 8.52 | 8.85 | 8.21 | 8.79 | +2.69% | |
| 8.48 | 8.93 | 8.38 | 8.56 | -0.58% | |
| 9.13 | 9.13 | 8.59 | 8.61 | -5.07% | |
| 9.27 | 9.31 | 8.66 | 9.07 | -2.05% | |
| 9.55 | 9.56 | 9.21 | 9.26 | -1.59% | |
| 9.80 | 9.97 | 9.36 | 9.41 | -3.88% | |
| 9.61 | 10.00 | 9.43 | 9.79 | +1.66% | |
| 9.74 | 9.74 | 9.45 | 9.63 | -1.13% | |
| 9.80 | 9.96 | 9.60 | 9.74 | -1.12% | |
| 10.16 | 10.16 | 9.81 | 9.85 | -2.67% | |
| 10.41 | 10.76 | 10.06 | 10.12 | -3.89% | |
| 11.05 | 11.05 | 10.32 | 10.53 | -5.56% | |
| 11.09 | 11.23 | 10.95 | 11.15 | +2.01% | |
| 11.02 | 11.18 | 10.60 | 10.93 | -0.73% | |
| 10.75 | 11.05 | 10.53 | 11.01 | +1.94% | |
| 11.01 | 11.06 | 10.60 | 10.80 | +0.23% | |
| 10.90 | 10.98 | 10.46 | 10.78 | -1.24% | |
| 11.29 | 11.29 | 10.55 | 10.91 | -3.71% | |
| 11.97 | 12.39 | 11.24 | 11.33 | -5.27% | |
| 12.41 | 13.00 | 11.70 | 11.96 | -1.97% | |
| 12.70 | 12.71 | 12.04 | 12.20 | -5.28% | |
| 13.52 | 13.82 | 12.71 | 12.88 | -4.80% | |
| 14.12 | 14.13 | 13.37 | 13.53 | -5.85% | |
| 14.29 | 14.68 | 13.92 | 14.37 | +0.35% | |
| 15.11 | 15.14 | 14.19 | 14.32 | -4.25% | |
| 14.49 | 14.97 | 14.25 | 14.96 | +2.96% | |
| 14.14 | 14.84 | 14.00 | 14.53 | +1.43% | |
| 14.51 | 14.71 | 14.14 | 14.32 | -1.45% | |
| 14.56 | 14.78 | 14.06 | 14.53 | -0.55% | |
| 14.67 | 15.02 | 14.33 | 14.61 | -1.28% | |
| 15.34 | 15.41 | 14.61 | 14.80 | -4.45% | |
| 15.02 | 15.68 | 14.92 | 15.49 | +5.09% | |
| 15.30 | 15.49 | 14.46 | 14.74 | -5.09% | |
| 15.54 | 16.16 | 15.20 | 15.53 | +1.17% | |
| 15.59 | 16.02 | 14.53 | 15.35 | -2.60% | |
| 16.02 | 17.15 | 15.66 | 15.76 | -0.19% | |
| 13.54 | 15.81 | 13.46 | 15.79 | +16.53% | |
| 13.86 | 13.93 | 13.39 | 13.55 | -2.87% | |
| 13.77 | 14.02 | 13.42 | 13.95 | +1.53% | |
| 14.20 | 14.41 | 13.70 | 13.74 | -3.03% | |
| 14.77 | 15.01 | 14.07 | 14.17 | -4.77% | |
| 14.33 | 15.52 | 14.32 | 14.88 | +3.84% | |
| 14.50 | 15.08 | 14.09 | 14.33 | -2.58% | |
| 14.00 | 15.09 | 13.95 | 14.71 | +3.52% | |
| 14.01 | 15.63 | 13.85 | 14.21 | +5.65% | |
| 13.50 | 13.98 | 13.20 | 13.45 | -1.10% | |
| 12.87 | 13.83 | 12.87 | 13.60 | +5.67% | |
| 13.05 | 13.15 | 12.71 | 12.87 | -0.54% | |
| 13.50 | 13.66 | 12.88 | 12.94 | -5.69% | |
| 12.98 | 13.74 | 12.82 | 13.72 | +5.78% | |
| 12.90 | 13.49 | 12.82 | 12.97 | -0.15% | |
| 12.94 | 13.05 | 12.56 | 12.99 | +0.23% | |
| 12.77 | 13.05 | 12.60 | 12.96 | +2.61% | |
| 12.83 | 12.96 | 12.48 | 12.63 | -1.17% | |
| 12.63 | 13.02 | 12.45 | 12.78 | -0.47% | |
| 13.68 | 14.14 | 12.68 | 12.84 | -2.06% | |
| 12.85 | 13.34 | 12.81 | 13.11 | +1.47% | |
| 13.36 | 13.60 | 12.72 | 12.92 | -3.00% | |
| 13.15 | 13.90 | 13.06 | 13.32 | -4.10% | |
| 14.24 | 14.40 | 13.24 | 13.89 | -2.59% | |
| 13.52 | 14.60 | 13.26 | 14.26 | +6.42% | |
| 14.24 | 14.24 | 13.23 | 13.40 | -6.49% | |
| 14.79 | 14.79 | 14.14 | 14.33 | -4.53% | |
| 15.17 | 15.45 | 13.81 | 15.01 | -1.31% | |
| 15.15 | 16.07 | 14.83 | 15.21 | -1.23% | |
| 15.66 | 16.80 | 14.70 | 15.40 | -3.21% | |
| 13.96 | 16.15 | 13.42 | 15.91 | +13.32% | |
| 14.11 | 14.70 | 13.75 | 14.04 | -0.07% | |
| 13.05 | 14.22 | 13.05 | 14.05 | +8.33% | |
| 13.86 | 14.12 | 12.56 | 12.97 | -7.69% | |
| 12.79 | 14.21 | 12.41 | 14.05 | +10.20% | |
| 11.84 | 13.08 | 11.84 | 12.75 | +9.82% | |
| 12.38 | 12.68 | 11.47 | 11.61 | -7.05% | |
| 13.13 | 13.73 | 12.33 | 12.49 | -3.92% | |
| 12.65 | 13.25 | 12.35 | 13.00 | +2.93% | |
| 11.88 | 13.02 | 11.66 | 12.63 | +5.51% | |
| 12.84 | 13.07 | 11.67 | 11.97 | -6.04% | |
| 12.73 | 13.22 | 12.25 | 12.74 | +1.76% | |
| 12.48 | 13.02 | 12.31 | 12.52 | +0.64% | |
| 13.36 | 13.49 | 12.03 | 12.44 | -8.19% | |
| 13.78 | 13.96 | 13.27 | 13.55 | +0.37% | |
| 13.67 | 13.80 | 13.08 | 13.50 | -1.60% | |
| 13.22 | 14.14 | 12.83 | 13.72 | +3.78% | |
| 12.64 | 13.35 | 12.64 | 13.22 | +4.09% | |
| 12.50 | 13.03 | 12.15 | 12.70 | +3.17% | |
| 12.20 | 12.47 | 11.85 | 12.31 | +2.84% | |
| 12.99 | 13.51 | 11.70 | 11.97 | -8.28% | |
| 12.59 | 13.13 | 11.95 | 13.05 | +3.82% | |
| 14.87 | 14.87 | 12.34 | 12.57 | -15.58% | |
| 17.15 | 17.16 | 14.71 | 14.89 | -13.18% | |
| 17.23 | 17.65 | 16.74 | 17.15 | -1.04% | |
| 16.87 | 17.48 | 16.30 | 17.33 | +2.97% | |
| 16.77 | 17.16 | 16.39 | 16.83 | +0.60% | |
| 16.50 | 17.21 | 16.01 | 16.73 | +2.20% | |
| 17.46 | 17.65 | 16.09 | 16.37 | -6.24% | |
| 17.19 | 17.69 | 16.85 | 17.46 | +0.92% | |
| 16.95 | 17.69 | 16.14 | 17.30 | +0.46% | |
| 16.26 | 17.30 | 16.23 | 17.22 | +6.76% | |
| 16.00 | 16.43 | 15.49 | 16.13 | -2.30% | |
| 17.88 | 18.00 | 16.40 | 16.51 | -7.87% | |
| 18.56 | 18.73 | 17.43 | 17.92 | -5.78% | |
| 19.25 | 19.49 | 18.36 | 19.02 | -1.14% | |
| 19.10 | 19.41 | 18.64 | 19.24 | -0.05% | |
| 19.07 | 19.49 | 18.68 | 19.25 | +0.26% | |
| 18.91 | 20.70 | 18.55 | 19.20 | -0.67% | |
| 19.93 | 20.51 | 19.14 | 19.33 | -3.64% | |
| 21.23 | 21.23 | 19.54 | 20.06 | -3.79% | |
| 20.67 | 21.27 | 20.20 | 20.85 | +1.12% | |
| 21.02 | 21.11 | 20.32 | 20.62 | -0.48% | |
| 20.57 | 21.48 | 20.57 | 20.72 | -0.53% | |
| 20.03 | 21.21 | 19.93 | 20.83 | +5.58% | |
| 20.64 | 21.55 | 19.59 | 19.73 | -4.22% | |
| 21.48 | 21.48 | 20.38 | 20.60 | -4.14% | |
| 22.52 | 23.68 | 21.17 | 21.49 | -5.00% | |
| 22.26 | 23.20 | 21.89 | 22.62 | +0.94% | |
| 23.24 | 23.67 | 22.25 | 22.41 | -5.04% | |
| 24.76 | 24.95 | 23.12 | 23.60 | -4.76% | |
| 24.40 | 24.78 | 23.65 | 24.78 | +3.66% | |
| 25.00 | 25.00 | 23.33 | 23.91 | -3.96% | |
| 23.87 | 25.03 | 23.38 | 24.89 | +3.67% | |
| 23.93 | 24.65 | 23.75 | 24.01 | +1.31% | |
| 23.84 | 24.60 | 23.31 | 23.70 | -0.59% | |
| 23.02 | 24.26 | 23.02 | 23.84 | +2.01% | |
| 24.99 | 25.25 | 23.18 | 23.37 | -5.77% | |
| 22.70 | 25.00 | 22.48 | 24.80 | +10.76% | |
| 24.00 | 24.23 | 22.37 | 22.39 | -6.12% | |
| 23.12 | 24.18 | 22.85 | 23.85 | +4.10% | |
| 22.53 | 23.49 | 21.42 | 22.91 | +5.19% | |
| 21.54 | 22.77 | 21.03 | 21.78 | +0.41% | |
| 21.16 | 22.66 | 21.16 | 21.69 | +2.26% | |
| 20.34 | 21.70 | 19.78 | 21.21 | +1.92% | |
| 20.14 | 22.00 | 19.76 | 20.81 | +3.74% | |
| 19.62 | 20.67 | 19.53 | 20.06 | +3.99% | |
| 19.48 | 20.16 | 19.18 | 19.29 | -1.93% | |
| 20.15 | 20.28 | 18.30 | 19.67 | -2.72% | |
| 19.90 | 21.09 | 19.90 | 20.22 | +0.40% | |
| 19.55 | 21.20 | 19.55 | 20.14 | +2.23% | |
| 19.32 | 19.89 | 18.73 | 19.70 | +0.77% | |
| 18.77 | 20.87 | 17.34 | 19.55 | +2.25% | |
| 20.23 | 21.48 | 19.03 | 19.12 | -7.94% | |
| 19.87 | 21.06 | 19.80 | 20.77 | +3.54% | |
| 19.99 | 20.55 | 18.90 | 20.06 | -0.40% | |
| 21.15 | 21.96 | 19.54 | 20.14 | -4.69% | |
| 21.37 | 22.64 | 20.53 | 21.13 | -0.56% | |
| 24.78 | 25.48 | 20.89 | 21.25 | -14.23% | |
| 24.69 | 25.62 | 23.94 | 24.78 | -1.45% | |
| 25.85 | 26.50 | 24.13 | 25.14 | -1.91% | |
| 26.29 | 27.75 | 25.48 | 25.63 | +0.51% | |
| 23.40 | 26.65 | 22.14 | 25.50 | +13.54% | |
| 21.61 | 22.77 | 21.61 | 22.46 | +1.86% | |
| 23.65 | 23.65 | 21.80 | 22.05 | -7.35% | |
| 23.60 | 24.25 | 22.71 | 23.80 | +2.01% | |
| 23.78 | 23.96 | 22.54 | 23.33 | -3.20% | |
| 23.88 | 24.83 | 23.31 | 24.10 | +0.42% | |
| 22.83 | 24.51 | 22.78 | 24.00 | +4.30% | |
| 23.64 | 23.65 | 22.28 | 23.01 | -2.00% | |
| 23.32 | 23.88 | 22.96 | 23.48 | +1.78% | |
| 22.86 | 23.48 | 22.15 | 23.07 | +1.59% | |
| 21.25 | 23.50 | 21.25 | 22.71 | +6.12% | |
| 21.25 | 22.32 | 20.88 | 21.40 | -0.93% | |
| 24.19 | 24.73 | 20.80 | 21.60 | -11.44% | |
| 24.39 | 25.37 | 20.37 | 24.39 | -3.90% | |
| 25.91 | 26.74 | 23.42 | 25.38 | -1.78% | |
| 25.48 | 27.25 | 25.20 | 25.84 | +1.81% | |
| 24.42 | 26.11 | 23.30 | 25.38 | +4.27% | |
| 23.51 | 25.18 | 21.95 | 24.34 | +2.66% | |
| 23.12 | 24.99 | 22.15 | 23.71 | +1.98% | |
| 22.60 | 23.75 | 21.07 | 23.25 | +2.38% | |
| 22.65 | 23.73 | 22.30 | 22.71 | +0.31% | |
| 23.50 | 24.92 | 22.00 | 22.64 | -6.37% | |
| 25.76 | 25.76 | 23.74 | 24.18 | -6.17% | |
| 24.58 | 26.76 | 24.53 | 25.77 | +4.04% | |
| 24.00 | 25.44 | 23.79 | 24.77 | +3.21% | |
| 24.52 | 25.05 | 23.00 | 24.00 | -3.26% | |
| 24.03 | 25.41 | 24.00 | 24.81 | +3.25% | |
| 25.25 | 26.01 | 24.03 | 24.03 | -4.94% | |
| 25.03 | 26.02 | 24.73 | 25.28 | +1.53% | |
| 25.02 | 25.84 | 24.57 | 24.90 | -1.43% | |
| 25.81 | 25.92 | 24.87 | 25.26 | -2.24% | |
| 24.41 | 27.89 | 24.22 | 25.84 | +7.13% | |
| 23.93 | 25.00 | 23.51 | 24.12 | +0.92% | |
| 23.20 | 24.33 | 22.67 | 23.90 | +0.59% | |
| 22.90 | 24.96 | 22.86 | 23.76 | +3.62% | |
| 23.54 | 23.99 | 22.38 | 22.93 | -2.26% | |
| 23.64 | 24.38 | 23.38 | 23.46 | -1.05% | |
| 23.88 | 25.12 | 23.05 | 23.71 | -0.25% | |
| 24.59 | 24.85 | 22.75 | 23.77 | -3.18% | |
| 24.34 | 25.75 | 24.34 | 24.55 | +1.03% | |
| 25.20 | 25.34 | 24.30 | 24.30 | -2.99% | |
| 25.91 | 26.49 | 24.69 | 25.05 | -2.64% | |
| 27.79 | 29.10 | 25.70 | 25.73 | -8.14% | |
| 28.99 | 29.21 | 25.81 | 28.01 | -3.35% | |
| 31.32 | 31.32 | 27.22 | 28.98 | -5.85% | |
| 31.28 | 32.28 | 30.01 | 30.78 | -2.56% | |
| 36.01 | 36.01 | 30.76 | 31.59 | -12.37% | |
| 35.03 | 37.00 | 34.42 | 36.05 | +2.74% | |
| 38.63 | 38.63 | 34.52 | 35.09 | -9.09% | |
| 38.00 | 39.07 | 37.00 | 38.60 | +3.40% | |
| 37.94 | 40.69 | 37.07 | 37.33 | -0.11% | |
| 33.79 | 45.00 | 32.93 | 37.37 | +12.12% | |
| 32.02 | 33.67 | 32.01 | 33.33 | +2.93% | |
| 32.30 | 34.78 | 32.30 | 32.38 | +0.97% | |
| 32.64 | 34.17 | 32.07 | 32.07 | -1.75% | |
| 32.40 | 33.61 | 32.00 | 32.64 | +0.74% | |
| 34.06 | 34.66 | 32.38 | 32.40 | -5.98% | |
| 33.80 | 35.16 | 32.75 | 34.46 | +3.14% | |
| 31.40 | 34.43 | 31.10 | 33.41 | +6.81% | |
| 29.09 | 32.80 | 29.00 | 31.28 | +6.87% | |
| 29.00 | 30.00 | 27.00 | 29.27 | +3.21% | |
| 25.87 | 28.86 | 25.51 | 28.36 | +12.32% | |
| 25.38 | 25.74 | 24.86 | 25.25 | -0.82% | |
| 22.48 | 25.59 | 21.39 | 25.46 | +14.12% | |
| 20.82 | 22.81 | 20.82 | 22.31 | +7.21% | |
| 22.10 | 22.49 | 20.59 | 20.81 | -5.84% | |
| 24.44 | 24.67 | 22.01 | 22.10 | -7.92% | |
| 24.41 | 25.20 | 22.57 | 24.00 | -1.68% | |
| 22.90 | 24.80 | 22.69 | 24.41 | +8.34% | |
| 22.74 | 23.66 | 22.03 | 22.53 | -0.84% | |
| 19.27 | 22.99 | 19.15 | 22.72 | +18.77% | |
| 17.77 | 19.13 | 17.32 | 19.13 | +9.75% | |
| 17.55 | 18.01 | 17.10 | 17.43 | +1.22% | |
| 18.00 | 18.13 | 16.96 | 17.22 | -3.96% | |
| 17.30 | 18.07 | 16.95 | 17.93 | +2.93% | |
| 16.99 | 18.80 | 16.99 | 17.42 | +2.89% | |
| 17.40 | 17.68 | 16.77 | 16.93 | -2.76% | |
| 17.00 | 17.63 | 16.92 | 17.41 | -1.25% | |
| 17.35 | 17.65 | 16.98 | 17.63 | +2.20% | |
| 17.80 | 18.60 | 16.09 | 17.25 | -2.43% | |
| 16.08 | 18.19 | 16.08 | 17.68 | +0.97% | |
| 17.43 | 17.73 | 16.57 | 17.51 | -2.07% | |
| 16.42 | 17.95 | 16.00 | 17.88 | +8.10% | |
| 16.15 | 17.46 | 16.12 | 16.54 | +3.70% | |
| 16.55 | 17.75 | 15.72 | 15.95 | -3.63% | |
| 16.87 | 17.31 | 15.94 | 16.55 | -0.66% | |
| 16.33 | 16.88 | 16.33 | 16.66 | +0.79% | |
| 16.59 | 17.04 | 16.29 | 16.53 | -0.36% | |
| 16.71 | 17.06 | 16.47 | 16.59 | -0.72% | |
| 17.11 | 17.59 | 16.48 | 16.71 | -3.02% | |
| 17.66 | 17.69 | 16.88 | 17.23 | -2.32% | |
| 18.51 | 18.60 | 17.50 | 17.64 | -3.71% | |
| 17.03 | 18.32 | 17.03 | 18.32 | +7.57% | |
| 17.40 | 17.40 | 16.00 | 17.03 | -1.67% | |
| 18.09 | 18.09 | 17.08 | 17.32 | -3.99% | |
| 16.70 | 18.04 | 16.70 | 18.04 | +9.33% | |
| 17.01 | 17.29 | 16.45 | 16.50 | -2.94% | |
| 17.29 | 18.08 | 16.84 | 17.00 | -2.19% | |
| 16.96 | 17.68 | 16.96 | 17.38 | +3.08% | |
| 16.83 | 16.86 | 15.68 | 16.86 | +0.18% | |
| 16.88 | 17.01 | 16.37 | 16.83 | +1.94% | |
| 18.76 | 19.44 | 16.45 | 16.51 | -12.51% | |
| 18.29 | 19.45 | 18.00 | 18.87 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the LYEL chart for longer ranges.