Madrigal Pharmaceuticals Stock Price History
NASDAQ: MDGLHealth CareBiotechnology: Pharmaceutical PreparationsUSD
471.75-5.16 (-1.08%)
At close: Oct 9, 4:00 PM ET · Delayed 15 min
MDGL price history at a glance
The price history for Madrigal Pharmaceuticals (MDGL) on this page begins on February 5, 2007, when the stock closed at $344.75; it most recently closed at $471.75 on October 5, 2026. The highest price in this record is $615.00, reached on December 22, 2025; the latest close is 23.3% below that peak. Across the 18 complete calendar years in the table, MDGL finished higher in 9 and lower in 9. Its best year was 2017 (+516.0%) and its worst was 2015 (-87.8%).
Over roughly 20 years the share price changed +36.8%, a 1.6% compound annual price return (excluding dividends). In the last 12 months alone, MDGL has gained 10.1%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2007
- $615.00
- Date of high
- Dec 22, 2025
- Low since 2007
- $5.25
- Date of low
- Feb 8, 2016
- 52-week high
- $615.00
- 52-week low
- $393.61
- IPO year
- 2007
- Last close
- $471.75
MDGL returns
1 week
-5.54%
1 month
-13.70%
3 months
-12.10%
6 months
-9.21%
Year to date
-18.99%
1 year
+10.14%
3 years
+236.08%
5 years
+447.46%
MDGL price return, excluding dividends.
MDGL annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 471.75 | -20.56% |
| 2025 | 593.87 | +85.76% |
| 2024 | 319.69 | +38.17% |
| 2023 | 231.38 | -20.28% |
| 2022 | 290.25 | +242.52% |
| 2021 | 84.74 | -23.77% |
| 2020 | 111.17 | +27.81% |
| 2019 | 86.98 | -22.37% |
| 2018 | 112.04 | +22.06% |
| 2017 | 91.79 | +516.04% |
| 2016 | 14.90 | +21.63% |
| 2015 | 12.25 | -87.80% |
| 2014 | 100.45 | -51.19% |
| 2013 | 205.80 | -40.18% |
| 2012 | 344.05 | +110.49% |
| 2011 | 163.45 | -23.69% |
| 2010 | 214.20 | +20.95% |
| 2009 | 177.10 | -17.99% |
| 2008 | 215.95 | -2.06% |
| 2007* | 220.50 | -36.04% |
* Partial year: the record begins after the start of 2007; return measured from the first available close.
2026 return is year to date.
MDGL daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 477.48 | 483.64 | 470.53 | 471.75 | -1.08% | |
| 486.37 | 491.57 | 466.06 | 476.91 | -2.22% | |
| 492.61 | 502.34 | 486.77 | 487.72 | -1.76% | |
| 497.08 | 504.06 | 478.71 | 496.45 | +0.57% | |
| 501.89 | 505.00 | 491.25 | 493.62 | -1.16% | |
| 505.00 | 505.00 | 491.05 | 499.40 | -0.06% | |
| 502.28 | 510.00 | 497.73 | 499.71 | -0.84% | |
| 513.10 | 515.00 | 501.81 | 503.96 | -1.08% | |
| 513.73 | 518.67 | 505.32 | 509.44 | -1.47% | |
| 515.10 | 525.00 | 502.68 | 517.04 | +0.09% | |
| 513.75 | 523.96 | 511.31 | 516.56 | +0.65% | |
| 513.65 | 521.77 | 510.57 | 513.21 | +0.04% | |
| 523.00 | 526.00 | 502.63 | 513.02 | -1.12% | |
| 525.77 | 528.42 | 516.62 | 518.83 | -0.60% | |
| 536.04 | 536.04 | 515.98 | 521.96 | -1.80% | |
| 535.08 | 537.73 | 526.65 | 531.52 | -0.54% | |
| 534.69 | 539.29 | 526.26 | 534.40 | +1.00% | |
| 523.00 | 529.93 | 517.45 | 529.09 | +1.11% | |
| 539.25 | 539.71 | 513.36 | 523.26 | -3.11% | |
| 540.00 | 541.35 | 527.97 | 540.06 | +1.04% | |
| 536.02 | 546.56 | 531.37 | 534.49 | +0.26% | |
| 543.12 | 543.12 | 519.10 | 533.12 | -2.48% | |
| 529.50 | 549.97 | 526.88 | 546.66 | +2.34% | |
| 534.17 | 540.00 | 526.67 | 534.16 | -1.28% | |
| 536.82 | 547.92 | 535.60 | 541.08 | -0.28% | |
| 548.83 | 552.08 | 540.44 | 542.61 | -0.79% | |
| 543.54 | 551.45 | 537.10 | 546.93 | +1.53% | |
| 540.03 | 548.60 | 532.66 | 538.71 | -0.24% | |
| 530.60 | 542.05 | 523.29 | 540.03 | +1.17% | |
| 539.38 | 542.16 | 528.29 | 533.76 | -1.83% | |
| 538.46 | 545.82 | 532.30 | 543.69 | +0.89% | |
| 510.14 | 550.33 | 507.48 | 538.88 | +5.22% | |
| 515.95 | 523.35 | 506.29 | 512.16 | +0.04% | |
| 515.89 | 517.00 | 507.18 | 511.97 | -0.92% | |
| 520.09 | 530.67 | 514.91 | 516.74 | -0.45% | |
| 537.01 | 539.73 | 518.65 | 519.09 | -3.90% | |
| 528.99 | 542.78 | 527.46 | 540.16 | +3.01% | |
| 524.50 | 533.68 | 514.57 | 524.37 | -0.10% | |
| 509.16 | 527.22 | 506.85 | 524.87 | +3.41% | |
| 504.34 | 509.89 | 494.90 | 507.56 | +0.04% | |
| 539.73 | 540.00 | 506.02 | 507.37 | -5.38% | |
| 536.00 | 544.49 | 527.59 | 536.20 | +0.17% | |
| 516.97 | 535.57 | 512.79 | 535.27 | +3.87% | |
| 502.92 | 517.48 | 501.21 | 515.34 | +1.04% | |
| 511.97 | 517.32 | 502.79 | 510.04 | -0.06% | |
| 513.28 | 524.45 | 509.00 | 510.36 | -0.73% | |
| 510.88 | 517.00 | 503.65 | 514.12 | +1.29% | |
| 492.73 | 513.76 | 489.23 | 507.56 | +5.30% | |
| 462.15 | 485.95 | 461.25 | 482.00 | +3.14% | |
| 490.00 | 490.23 | 460.11 | 467.32 | -5.23% | |
| 505.55 | 510.55 | 447.01 | 493.11 | -9.83% | |
| 541.59 | 550.89 | 536.00 | 546.88 | +1.50% | |
| 551.50 | 561.15 | 532.96 | 538.80 | -2.26% | |
| 555.00 | 566.18 | 548.68 | 551.25 | +1.24% | |
| 544.37 | 547.91 | 537.00 | 544.51 | +0.21% | |
| 537.65 | 549.04 | 526.61 | 543.35 | +1.06% | |
| 546.78 | 552.73 | 536.42 | 537.65 | -1.67% | |
| 534.50 | 548.53 | 534.50 | 546.79 | +2.07% | |
| 555.00 | 555.05 | 533.00 | 535.69 | -3.21% | |
| 538.85 | 560.09 | 536.01 | 553.48 | +1.46% | |
| 549.62 | 553.55 | 532.64 | 545.53 | -0.86% | |
| 536.05 | 555.70 | 529.63 | 550.25 | +2.49% | |
| 526.26 | 539.45 | 522.70 | 536.86 | +1.10% | |
| 534.05 | 539.15 | 526.14 | 531.00 | -1.06% | |
| 564.94 | 564.94 | 529.50 | 536.70 | -4.16% | |
| 564.87 | 569.44 | 548.36 | 560.01 | -0.95% | |
| 542.43 | 566.68 | 540.87 | 565.40 | +3.67% | |
| 534.96 | 554.01 | 529.80 | 545.36 | +3.00% | |
| 523.68 | 537.24 | 522.06 | 529.48 | +0.26% | |
| 512.34 | 529.73 | 507.60 | 528.10 | +2.67% | |
| 539.67 | 542.97 | 512.74 | 514.39 | -4.20% | |
| 526.32 | 545.87 | 520.60 | 536.95 | +1.83% | |
| 520.34 | 531.99 | 506.00 | 527.28 | +2.85% | |
| 517.66 | 532.33 | 505.63 | 512.65 | -0.22% | |
| 507.06 | 520.86 | 505.05 | 513.79 | +0.79% | |
| 516.83 | 527.71 | 509.07 | 509.76 | -0.71% | |
| 513.36 | 522.00 | 507.57 | 513.43 | +0.11% | |
| 513.23 | 517.54 | 500.80 | 512.88 | +1.41% | |
| 500.38 | 511.28 | 485.56 | 505.75 | +1.18% | |
| 499.65 | 509.04 | 493.05 | 499.86 | -0.27% | |
| 505.34 | 507.75 | 493.00 | 501.19 | +0.29% | |
| 479.98 | 500.71 | 474.52 | 499.76 | +3.95% | |
| 474.28 | 486.10 | 469.08 | 480.77 | +1.37% | |
| 467.50 | 478.78 | 460.89 | 474.28 | +0.63% | |
| 477.93 | 485.55 | 471.32 | 471.32 | -1.17% | |
| 474.52 | 480.50 | 470.83 | 476.89 | +2.06% | |
| 486.80 | 490.00 | 465.00 | 467.28 | -4.05% | |
| 494.49 | 495.18 | 481.62 | 486.98 | -1.19% | |
| 495.32 | 497.83 | 486.17 | 492.83 | +0.96% | |
| 450.61 | 490.12 | 445.20 | 488.15 | +7.79% | |
| 475.80 | 476.96 | 451.74 | 452.86 | -5.90% | |
| 495.74 | 496.07 | 479.00 | 481.23 | -3.23% | |
| 514.57 | 520.31 | 496.63 | 497.27 | -3.62% | |
| 523.96 | 529.86 | 513.07 | 515.96 | -2.22% | |
| 524.30 | 535.76 | 521.16 | 527.67 | +0.65% | |
| 516.48 | 529.00 | 508.01 | 524.28 | +1.36% | |
| 513.00 | 520.89 | 507.06 | 517.26 | +0.71% | |
| 510.96 | 519.99 | 503.26 | 513.59 | +0.02% | |
| 518.72 | 523.16 | 499.34 | 513.47 | +0.32% | |
| 520.00 | 528.99 | 508.86 | 511.82 | -1.99% | |
| 522.19 | 523.85 | 501.02 | 522.23 | -0.28% | |
| 540.56 | 543.78 | 522.40 | 523.69 | -3.00% | |
| 522.34 | 547.24 | 518.32 | 539.89 | +4.05% | |
| 510.44 | 523.57 | 506.03 | 518.87 | +1.69% | |
| 494.06 | 511.11 | 490.13 | 510.26 | +2.66% | |
| 511.32 | 513.36 | 493.57 | 497.03 | -2.55% | |
| 535.00 | 541.57 | 510.00 | 510.04 | -4.64% | |
| 534.10 | 542.00 | 512.28 | 534.86 | -0.90% | |
| 531.20 | 559.00 | 519.88 | 539.73 | +7.42% | |
| 518.22 | 522.01 | 497.23 | 502.47 | -3.12% | |
| 510.50 | 524.80 | 509.66 | 518.66 | +0.96% | |
| 518.11 | 520.78 | 504.01 | 513.72 | -0.71% | |
| 518.58 | 523.85 | 511.00 | 517.39 | -0.23% | |
| 512.60 | 519.05 | 501.59 | 518.58 | +0.37% | |
| 523.98 | 528.28 | 515.08 | 516.69 | -0.65% | |
| 510.88 | 524.31 | 508.52 | 520.09 | +1.50% | |
| 518.00 | 522.18 | 500.97 | 512.39 | -1.22% | |
| 529.14 | 535.29 | 516.49 | 518.74 | -1.97% | |
| 531.69 | 536.32 | 523.24 | 529.14 | +0.27% | |
| 526.49 | 534.39 | 516.44 | 527.69 | +0.11% | |
| 530.66 | 530.66 | 521.92 | 527.11 | -0.92% | |
| 529.94 | 536.86 | 522.81 | 532.02 | +1.38% | |
| 515.11 | 526.87 | 510.58 | 524.76 | +1.19% | |
| 529.81 | 529.81 | 510.70 | 518.58 | -1.22% | |
| 532.10 | 539.17 | 518.80 | 524.99 | -0.13% | |
| 524.28 | 534.52 | 523.26 | 525.67 | +1.17% | |
| 525.00 | 526.50 | 507.54 | 519.61 | -0.89% | |
| 516.96 | 525.99 | 510.64 | 524.30 | +0.88% | |
| 514.83 | 521.00 | 503.93 | 519.75 | +1.54% | |
| 527.96 | 530.59 | 504.70 | 511.89 | -4.12% | |
| 538.36 | 547.18 | 530.41 | 533.88 | -2.38% | |
| 531.19 | 547.98 | 522.49 | 546.89 | +3.22% | |
| 531.32 | 545.26 | 525.00 | 529.84 | +1.22% | |
| 514.64 | 538.80 | 510.40 | 523.47 | +3.59% | |
| 511.00 | 522.00 | 502.14 | 505.34 | -1.05% | |
| 515.70 | 523.34 | 498.03 | 510.68 | -1.56% | |
| 457.29 | 572.20 | 455.56 | 518.76 | +12.30% | |
| 448.79 | 471.72 | 448.49 | 461.93 | +3.80% | |
| 445.00 | 449.14 | 437.05 | 445.04 | -0.60% | |
| 447.96 | 454.98 | 442.40 | 447.72 | +1.49% | |
| 454.81 | 466.90 | 438.87 | 441.16 | -2.88% | |
| 442.64 | 460.00 | 439.68 | 454.22 | +2.76% | |
| 440.00 | 446.18 | 427.76 | 442.00 | -0.27% | |
| 440.02 | 452.20 | 440.02 | 443.18 | +0.53% | |
| 446.84 | 455.00 | 440.00 | 440.83 | -0.90% | |
| 440.64 | 448.07 | 434.30 | 444.83 | +1.39% | |
| 427.28 | 441.37 | 421.55 | 438.73 | +1.67% | |
| 427.95 | 438.00 | 426.04 | 431.53 | -0.29% | |
| 433.04 | 443.42 | 430.21 | 432.78 | -0.10% | |
| 429.42 | 438.84 | 418.72 | 433.20 | +0.09% | |
| 431.65 | 439.43 | 421.88 | 432.83 | -1.48% | |
| 434.50 | 444.43 | 426.97 | 439.34 | +1.04% | |
| 429.86 | 443.61 | 423.98 | 434.80 | +2.10% | |
| 428.69 | 433.56 | 416.21 | 425.85 | -2.24% | |
| 430.23 | 438.73 | 421.45 | 435.62 | +0.84% | |
| 441.33 | 442.50 | 430.01 | 432.00 | -3.11% | |
| 437.20 | 448.13 | 430.00 | 445.85 | +2.49% | |
| 440.00 | 447.01 | 434.67 | 435.01 | -1.13% | |
| 437.92 | 452.30 | 431.14 | 440.00 | +0.50% | |
| 424.20 | 440.99 | 424.20 | 437.79 | +0.64% | |
| 435.01 | 448.15 | 424.49 | 435.01 | -0.43% | |
| 452.02 | 461.98 | 427.78 | 436.87 | -11.11% | |
| 486.71 | 498.10 | 480.00 | 491.49 | +0.86% | |
| 462.37 | 495.00 | 462.04 | 487.32 | +4.87% | |
| 474.31 | 482.99 | 458.07 | 464.71 | -1.92% | |
| 483.90 | 484.25 | 468.08 | 473.79 | -1.50% | |
| 483.03 | 483.03 | 463.53 | 481.00 | +0.45% | |
| 488.30 | 499.55 | 475.34 | 478.83 | -1.93% | |
| 477.60 | 490.50 | 471.39 | 488.26 | +2.23% | |
| 475.69 | 482.88 | 465.20 | 477.60 | +3.06% | |
| 478.90 | 486.88 | 458.00 | 463.42 | -3.17% | |
| 478.75 | 482.06 | 472.52 | 478.61 | -0.80% | |
| 486.17 | 491.29 | 467.86 | 482.45 | -1.49% | |
| 483.11 | 497.73 | 481.02 | 489.73 | +0.09% | |
| 489.75 | 497.54 | 480.02 | 489.31 | -1.09% | |
| 497.38 | 500.15 | 485.96 | 494.69 | -0.37% | |
| 504.36 | 506.40 | 492.00 | 496.54 | -0.77% | |
| 495.03 | 501.68 | 487.88 | 500.39 | +0.24% | |
| 476.71 | 502.36 | 474.86 | 499.17 | +3.90% | |
| 497.32 | 499.00 | 465.98 | 480.45 | -3.53% | |
| 496.97 | 504.00 | 492.01 | 498.04 | +0.22% | |
| 498.30 | 505.00 | 492.69 | 496.97 | -1.58% | |
| 491.94 | 506.61 | 483.55 | 504.95 | +0.65% | |
| 495.75 | 511.94 | 492.50 | 501.68 | +1.17% | |
| 503.65 | 510.50 | 495.36 | 495.88 | -1.85% | |
| 492.60 | 508.76 | 487.19 | 505.23 | +2.29% | |
| 511.57 | 514.36 | 493.19 | 493.90 | -3.26% | |
| 513.87 | 517.71 | 504.49 | 510.53 | -0.69% | |
| 554.99 | 555.10 | 511.03 | 514.06 | -7.58% | |
| 559.91 | 568.00 | 547.80 | 556.22 | -0.88% | |
| 560.87 | 589.98 | 558.29 | 561.13 | +0.56% | |
| 575.02 | 578.50 | 532.45 | 558.01 | -5.16% | |
| 592.21 | 592.99 | 572.52 | 588.40 | -0.92% | |
| 582.02 | 598.79 | 580.00 | 593.87 | +1.98% | |
| 583.21 | 592.72 | 581.52 | 582.34 | -0.24% | |
| 588.39 | 590.00 | 578.00 | 583.73 | -0.97% | |
| 598.00 | 599.98 | 587.02 | 589.47 | -1.58% | |
| 608.34 | 608.34 | 597.70 | 598.91 | -0.65% | |
| 601.36 | 615.00 | 601.36 | 602.82 | +0.10% | |
| 597.61 | 609.80 | 593.00 | 602.21 | -0.10% | |
| 585.21 | 609.98 | 585.21 | 602.83 | +2.00% | |
| 552.42 | 593.59 | 551.38 | 591.02 | +8.56% | |
| 546.00 | 555.50 | 535.33 | 544.41 | -0.33% | |
| 551.90 | 561.00 | 544.85 | 546.19 | -1.51% | |
| 554.78 | 560.00 | 544.24 | 554.57 | -1.07% | |
| 571.84 | 573.67 | 552.75 | 560.55 | -1.91% | |
| 570.11 | 577.21 | 561.05 | 571.44 | +0.02% | |
| 559.13 | 589.67 | 554.00 | 571.33 | +3.41% | |
| 552.97 | 555.39 | 546.20 | 552.47 | -0.26% | |
| 565.80 | 569.83 | 550.70 | 553.92 | -2.58% | |
| 576.90 | 576.97 | 561.20 | 568.57 | -1.51% | |
| 585.39 | 593.00 | 573.00 | 577.30 | -1.52% | |
| 582.59 | 594.27 | 573.00 | 586.21 | +1.09% | |
| 579.67 | 592.88 | 570.50 | 579.89 | +1.18% | |
| 579.90 | 598.77 | 569.04 | 573.15 | -1.09% | |
| 593.82 | 594.03 | 577.59 | 579.45 | -2.94% | |
| 600.00 | 605.00 | 590.34 | 596.98 | -0.67% | |
| 592.04 | 604.81 | 585.09 | 601.03 | +1.52% | |
| 588.27 | 594.46 | 566.99 | 592.04 | +0.70% | |
| 547.96 | 594.99 | 545.00 | 587.92 | +7.29% | |
| 542.85 | 565.15 | 535.00 | 547.96 | +1.08% | |
| 562.71 | 571.16 | 540.01 | 542.12 | -2.43% | |
| 554.39 | 570.24 | 553.24 | 555.60 | -0.61% | |
| 545.38 | 577.90 | 545.38 | 558.99 | +1.01% | |
| 525.00 | 555.12 | 520.45 | 553.42 | +4.57% | |
| 509.50 | 534.95 | 505.00 | 529.21 | +2.77% | |
| 527.37 | 531.00 | 513.82 | 514.93 | -2.65% | |
| 536.39 | 542.19 | 520.00 | 528.94 | -2.32% | |
| 491.39 | 544.25 | 491.39 | 541.50 | +9.20% | |
| 498.00 | 505.05 | 486.04 | 495.88 | +1.35% | |
| 488.03 | 494.55 | 476.61 | 489.26 | +0.14% | |
| 471.22 | 491.91 | 471.22 | 488.58 | +2.67% | |
| 450.90 | 496.98 | 446.20 | 475.87 | +7.02% | |
| 406.22 | 469.95 | 405.00 | 444.64 | +7.83% | |
| 421.64 | 430.50 | 399.00 | 412.35 | -1.56% | |
| 428.50 | 433.12 | 410.50 | 418.90 | -2.02% | |
| 423.74 | 434.98 | 420.51 | 427.52 | +1.40% | |
| 427.07 | 434.48 | 393.61 | 421.60 | -1.77% | |
| 430.14 | 435.00 | 426.66 | 429.18 | -1.51% | |
| 423.61 | 436.84 | 423.61 | 435.78 | +3.39% | |
| 426.63 | 429.98 | 417.35 | 421.50 | -0.56% | |
| 415.96 | 424.92 | 415.00 | 423.87 | +1.90% | |
| 426.57 | 430.25 | 413.82 | 415.95 | -3.27% | |
| 435.86 | 445.06 | 427.06 | 430.00 | -2.27% | |
| 442.97 | 442.97 | 418.56 | 439.97 | +0.24% | |
| 434.95 | 440.17 | 427.52 | 438.90 | -0.73% | |
| 433.45 | 449.02 | 433.45 | 442.13 | +2.00% | |
| 444.33 | 451.41 | 425.02 | 433.45 | -0.84% | |
| 426.56 | 439.45 | 420.02 | 437.10 | +2.19% | |
| 427.07 | 430.75 | 420.00 | 427.73 | -0.44% | |
| 428.71 | 445.00 | 416.29 | 429.60 | +0.30% | |
| 433.96 | 443.60 | 425.60 | 428.30 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the MDGL chart for longer ranges.