Orchestra BioMed Stock Price History
NASDAQ: OBIOHealth Care Medicinal Chemicals and Botanical Products USD
At close: Oct 9, 4:00 PM ET · Delayed 15 min
OBIO price history at a glance
The price history for Orchestra BioMed (OBIO) on this page begins on August 3, 2020, when the stock closed at $11.90; it most recently closed at $5.95 on October 5, 2026. The highest price in this record is $23.39, reached on April 3, 2023; the latest close is 74.6% below that peak. Across the 5 complete calendar years in the table, OBIO finished higher in 0 and lower in 5. Its best year was 2022 (-1.0%) and its worst was 2024 (-36.6%).
Over roughly 6 years the share price changed -50.0%, a -10.6% compound annual price return (excluding dividends). In the last 12 months alone, OBIO has gained 107.3%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2020
- $23.39
- Date of high
- Apr 3, 2023
- Low since 2020
- $2.20
- Date of low
- Sep 22, 2025
- 52-week high
- $6.50
- 52-week low
- $3.06
- IPO year
- 2020
- Last close
- $5.95
OBIO returns
1 week
0.00%
1 month
+9.17%
3 months
+49.12%
6 months
+44.07%
Year to date
+43.37%
1 year
+107.32%
3 years
+15.31%
5 years
-39.59%
OBIO price return, excluding dividends.
OBIO annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 5.95 | +38.05% |
| 2025 | 4.31 | -25.56% |
| 2024 | 5.79 | -36.58% |
| 2023 | 9.13 | -8.52% |
| 2022 | 9.98 | -0.99% |
| 2021 | 10.08 | -21.31% |
| 2020* | 12.81 | +7.65% |
* Partial year: the record begins after the start of 2020; return measured from the first available close.
2026 return is year to date.
OBIO daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 5.73 | 5.97 | 5.56 | 5.95 | +3.84% | |
| 5.75 | 5.83 | 5.51 | 5.73 | +1.24% | |
| 5.79 | 5.86 | 5.64 | 5.66 | -3.08% | |
| 6.05 | 6.12 | 5.82 | 5.84 | -3.15% | |
| 5.89 | 6.09 | 5.79 | 6.03 | +1.34% | |
| 6.40 | 6.44 | 5.77 | 5.95 | -6.30% | |
| 6.27 | 6.50 | 6.23 | 6.35 | +2.09% | |
| 6.09 | 6.29 | 6.00 | 6.22 | +2.30% | |
| 5.89 | 6.09 | 5.83 | 6.08 | +3.23% | |
| 5.95 | 5.95 | 5.80 | 5.89 | -1.01% | |
| 5.99 | 6.17 | 5.86 | 5.95 | 0.00% | |
| 5.90 | 6.05 | 5.75 | 5.95 | +0.34% | |
| 6.10 | 6.20 | 5.90 | 5.93 | -4.66% | |
| 6.15 | 6.48 | 6.05 | 6.22 | -0.48% | |
| 6.04 | 6.29 | 5.85 | 6.25 | +2.80% | |
| 5.74 | 6.30 | 5.71 | 6.08 | +5.19% | |
| 6.03 | 6.26 | 5.73 | 5.78 | -3.83% | |
| 6.05 | 6.28 | 5.93 | 6.01 | -0.50% | |
| 6.00 | 6.13 | 5.93 | 6.04 | +2.37% | |
| 6.07 | 6.20 | 5.74 | 5.90 | -3.59% | |
| 5.87 | 6.25 | 5.76 | 6.12 | +5.34% | |
| 5.85 | 6.08 | 5.68 | 5.81 | +6.61% | |
| 5.31 | 5.46 | 5.26 | 5.45 | +0.37% | |
| 5.18 | 5.51 | 4.80 | 5.43 | +6.89% | |
| 4.71 | 5.14 | 4.71 | 5.08 | +7.17% | |
| 4.97 | 4.97 | 4.71 | 4.74 | -4.24% | |
| 4.92 | 5.01 | 4.83 | 4.95 | +1.02% | |
| 5.02 | 5.35 | 4.88 | 4.90 | -2.78% | |
| 5.23 | 5.33 | 5.00 | 5.04 | -2.80% | |
| 5.23 | 5.23 | 5.06 | 5.19 | +1.47% | |
| 5.23 | 5.42 | 5.10 | 5.11 | -2.85% | |
| 5.36 | 5.45 | 5.16 | 5.26 | -1.87% | |
| 5.37 | 5.50 | 5.35 | 5.36 | -1.47% | |
| 5.35 | 5.48 | 5.21 | 5.44 | +1.49% | |
| 5.45 | 5.53 | 5.27 | 5.36 | -1.29% | |
| 5.53 | 5.58 | 5.38 | 5.43 | -2.16% | |
| 5.49 | 5.78 | 5.49 | 5.55 | -1.94% | |
| 4.74 | 5.77 | 4.69 | 5.66 | +19.92% | |
| 4.41 | 4.72 | 4.36 | 4.72 | +7.03% | |
| 4.47 | 4.47 | 4.29 | 4.41 | -0.90% | |
| 4.46 | 4.55 | 4.40 | 4.45 | +0.68% | |
| 4.39 | 4.47 | 4.20 | 4.42 | +0.45% | |
| 4.27 | 4.66 | 4.27 | 4.40 | -1.35% | |
| 4.25 | 4.50 | 4.25 | 4.46 | +5.19% | |
| 4.17 | 4.29 | 4.14 | 4.24 | +2.17% | |
| 4.21 | 4.26 | 4.03 | 4.15 | -1.66% | |
| 4.27 | 4.27 | 4.14 | 4.22 | -1.17% | |
| 4.10 | 4.29 | 4.10 | 4.27 | +3.64% | |
| 3.97 | 4.15 | 3.94 | 4.12 | +3.52% | |
| 3.98 | 4.06 | 3.84 | 3.98 | -0.25% | |
| 3.83 | 4.00 | 3.83 | 3.99 | +5.00% | |
| 3.85 | 3.95 | 3.78 | 3.80 | -1.55% | |
| 3.83 | 3.89 | 3.82 | 3.86 | +1.05% | |
| 3.80 | 3.88 | 3.75 | 3.82 | +2.14% | |
| 3.67 | 3.79 | 3.62 | 3.74 | +2.75% | |
| 3.59 | 3.75 | 3.56 | 3.64 | +0.28% | |
| 3.68 | 3.73 | 3.59 | 3.63 | -1.63% | |
| 3.71 | 3.77 | 3.59 | 3.69 | -0.54% | |
| 3.69 | 3.75 | 3.63 | 3.71 | +0.82% | |
| 3.64 | 3.74 | 3.63 | 3.68 | -1.08% | |
| 3.65 | 3.77 | 3.61 | 3.72 | +1.92% | |
| 3.70 | 3.82 | 3.63 | 3.65 | -1.08% | |
| 3.83 | 3.96 | 3.68 | 3.69 | -3.40% | |
| 3.97 | 4.03 | 3.82 | 3.82 | -4.26% | |
| 3.91 | 4.00 | 3.81 | 3.99 | +1.79% | |
| 3.92 | 3.97 | 3.85 | 3.92 | 0.00% | |
| 3.92 | 3.95 | 3.80 | 3.92 | -1.01% | |
| 4.12 | 4.25 | 3.89 | 3.96 | -2.94% | |
| 4.16 | 4.25 | 4.05 | 4.08 | -2.63% | |
| 4.30 | 4.47 | 4.19 | 4.19 | -2.56% | |
| 4.32 | 4.36 | 4.21 | 4.30 | -0.35% | |
| 4.74 | 4.79 | 4.26 | 4.32 | -9.16% | |
| 4.21 | 4.80 | 4.09 | 4.75 | +12.03% | |
| 3.90 | 4.31 | 3.90 | 4.24 | +8.72% | |
| 4.00 | 4.07 | 3.85 | 3.90 | -2.01% | |
| 4.05 | 4.12 | 3.97 | 3.98 | -1.49% | |
| 4.02 | 4.12 | 3.94 | 4.04 | -0.98% | |
| 4.03 | 4.12 | 3.89 | 4.08 | +2.26% | |
| 3.89 | 4.04 | 3.84 | 3.99 | +3.10% | |
| 3.90 | 4.01 | 3.84 | 3.87 | +0.52% | |
| 4.00 | 4.06 | 3.85 | 3.85 | -3.02% | |
| 4.12 | 4.14 | 3.92 | 3.97 | -3.17% | |
| 4.09 | 4.17 | 4.04 | 4.10 | +0.74% | |
| 4.04 | 4.12 | 3.94 | 4.07 | +1.24% | |
| 4.02 | 4.13 | 4.00 | 4.02 | -0.25% | |
| 3.99 | 4.09 | 3.92 | 4.03 | +2.03% | |
| 3.95 | 4.06 | 3.88 | 3.95 | +1.28% | |
| 3.97 | 4.14 | 3.81 | 3.90 | -2.26% | |
| 3.86 | 4.04 | 3.86 | 3.99 | +3.37% | |
| 3.90 | 3.92 | 3.79 | 3.86 | -1.28% | |
| 3.82 | 3.96 | 3.77 | 3.91 | +2.09% | |
| 3.91 | 4.04 | 3.80 | 3.83 | -2.05% | |
| 3.99 | 4.01 | 3.89 | 3.91 | -1.76% | |
| 3.95 | 4.03 | 3.94 | 3.98 | +0.76% | |
| 3.95 | 4.12 | 3.95 | 3.95 | -0.50% | |
| 4.09 | 4.10 | 3.88 | 3.97 | -2.22% | |
| 4.12 | 4.14 | 4.05 | 4.06 | -0.98% | |
| 3.94 | 4.14 | 3.94 | 4.10 | +3.02% | |
| 4.04 | 4.05 | 3.94 | 3.98 | -0.50% | |
| 3.98 | 4.16 | 3.96 | 4.00 | +0.50% | |
| 3.84 | 3.98 | 3.75 | 3.98 | +6.99% | |
| 4.03 | 4.05 | 3.70 | 3.72 | -9.49% | |
| 4.10 | 4.15 | 4.03 | 4.11 | +1.23% | |
| 4.07 | 4.14 | 3.93 | 4.06 | 0.00% | |
| 3.90 | 4.06 | 3.78 | 4.06 | +3.84% | |
| 4.05 | 4.11 | 3.90 | 3.91 | -3.22% | |
| 3.99 | 4.12 | 3.90 | 4.04 | +2.80% | |
| 4.11 | 4.24 | 3.88 | 3.93 | -4.38% | |
| 4.06 | 4.18 | 4.00 | 4.11 | +2.49% | |
| 4.05 | 4.10 | 3.95 | 4.01 | -0.25% | |
| 4.00 | 4.16 | 4.00 | 4.02 | +1.26% | |
| 4.06 | 4.06 | 3.94 | 3.97 | -0.50% | |
| 3.85 | 4.00 | 3.78 | 3.99 | +5.00% | |
| 3.90 | 3.90 | 3.78 | 3.80 | -2.56% | |
| 4.09 | 4.09 | 3.85 | 3.90 | -4.88% | |
| 4.13 | 4.22 | 4.06 | 4.10 | -0.73% | |
| 4.14 | 4.22 | 4.01 | 4.13 | -0.48% | |
| 4.22 | 4.23 | 4.09 | 4.15 | -1.43% | |
| 4.31 | 4.40 | 4.16 | 4.21 | -0.47% | |
| 4.37 | 4.56 | 4.20 | 4.23 | -2.76% | |
| 4.54 | 4.70 | 4.31 | 4.35 | -5.02% | |
| 4.53 | 4.72 | 4.36 | 4.58 | +2.46% | |
| 4.62 | 4.62 | 4.43 | 4.47 | -2.19% | |
| 4.51 | 4.62 | 4.51 | 4.57 | +1.33% | |
| 4.40 | 4.54 | 4.33 | 4.51 | +4.88% | |
| 4.12 | 4.34 | 4.12 | 4.30 | +4.12% | |
| 4.23 | 4.32 | 4.10 | 4.13 | -2.36% | |
| 4.21 | 4.43 | 4.18 | 4.23 | -0.94% | |
| 4.47 | 4.47 | 4.26 | 4.27 | +0.23% | |
| 4.22 | 4.44 | 4.15 | 4.26 | +0.47% | |
| 4.29 | 4.42 | 4.23 | 4.24 | -0.70% | |
| 4.25 | 4.39 | 4.09 | 4.27 | -1.61% | |
| 4.31 | 4.49 | 4.13 | 4.34 | +2.12% | |
| 4.19 | 4.30 | 4.08 | 4.25 | +4.42% | |
| 4.25 | 4.26 | 4.04 | 4.07 | -4.46% | |
| 4.44 | 4.46 | 4.18 | 4.26 | -5.12% | |
| 4.52 | 4.64 | 4.46 | 4.49 | -1.75% | |
| 4.73 | 4.83 | 4.56 | 4.57 | -1.93% | |
| 4.75 | 4.75 | 4.48 | 4.66 | -2.10% | |
| 4.68 | 4.83 | 4.63 | 4.76 | +2.59% | |
| 4.57 | 4.72 | 4.47 | 4.64 | 0.00% | |
| 4.38 | 4.64 | 4.38 | 4.64 | +2.88% | |
| 4.54 | 4.72 | 4.35 | 4.51 | -2.17% | |
| 4.64 | 4.72 | 4.57 | 4.61 | +1.32% | |
| 4.09 | 4.66 | 4.09 | 4.55 | +8.33% | |
| 4.38 | 4.45 | 4.13 | 4.20 | -4.11% | |
| 4.61 | 4.70 | 4.23 | 4.38 | -4.78% | |
| 4.60 | 4.72 | 4.50 | 4.60 | -0.86% | |
| 4.70 | 4.89 | 4.59 | 4.64 | -0.64% | |
| 4.24 | 4.67 | 4.22 | 4.67 | +8.10% | |
| 4.42 | 4.54 | 4.25 | 4.32 | -4.21% | |
| 4.50 | 4.71 | 4.39 | 4.51 | -1.10% | |
| 4.43 | 4.67 | 4.43 | 4.56 | +4.59% | |
| 4.21 | 4.55 | 4.21 | 4.36 | -0.46% | |
| 4.25 | 4.46 | 4.19 | 4.38 | 0.00% | |
| 4.20 | 4.46 | 4.20 | 4.38 | +1.15% | |
| 4.35 | 4.43 | 4.26 | 4.33 | -0.46% | |
| 4.16 | 4.39 | 4.15 | 4.35 | +5.58% | |
| 4.02 | 4.15 | 3.99 | 4.12 | +2.23% | |
| 3.87 | 4.08 | 3.85 | 4.03 | +2.81% | |
| 3.92 | 4.12 | 3.76 | 3.92 | -1.51% | |
| 3.98 | 4.04 | 3.84 | 3.98 | -0.50% | |
| 3.83 | 4.10 | 3.83 | 4.00 | +4.17% | |
| 3.83 | 3.94 | 3.77 | 3.84 | +0.26% | |
| 3.84 | 3.99 | 3.78 | 3.83 | +0.26% | |
| 4.11 | 4.22 | 3.78 | 3.82 | -5.91% | |
| 4.16 | 4.16 | 3.89 | 4.06 | -2.64% | |
| 3.94 | 4.25 | 3.94 | 4.17 | +6.38% | |
| 3.91 | 4.08 | 3.80 | 3.92 | +0.26% | |
| 3.71 | 4.02 | 3.62 | 3.91 | +5.39% | |
| 3.75 | 3.86 | 3.62 | 3.71 | -2.37% | |
| 4.11 | 4.14 | 3.77 | 3.80 | -6.86% | |
| 4.07 | 4.24 | 3.84 | 4.08 | +1.49% | |
| 3.52 | 4.21 | 3.52 | 4.02 | +15.19% | |
| 3.68 | 3.78 | 3.46 | 3.49 | -6.43% | |
| 3.90 | 3.99 | 3.69 | 3.73 | -5.09% | |
| 4.13 | 4.13 | 3.90 | 3.93 | -5.53% | |
| 3.96 | 4.21 | 3.92 | 4.16 | +5.32% | |
| 4.02 | 4.16 | 3.93 | 3.95 | -2.23% | |
| 4.10 | 4.37 | 4.01 | 4.04 | -2.18% | |
| 4.10 | 4.27 | 4.10 | 4.13 | +0.98% | |
| 4.05 | 4.18 | 3.98 | 4.09 | +1.24% | |
| 4.10 | 4.19 | 3.92 | 4.04 | -4.27% | |
| 4.23 | 4.32 | 4.15 | 4.22 | +1.20% | |
| 4.44 | 4.53 | 4.06 | 4.17 | -6.50% | |
| 4.29 | 4.51 | 4.29 | 4.46 | +4.21% | |
| 4.69 | 4.70 | 4.26 | 4.28 | -8.15% | |
| 4.80 | 4.89 | 4.48 | 4.66 | -2.92% | |
| 4.96 | 5.00 | 4.71 | 4.80 | -0.83% | |
| 4.80 | 4.91 | 4.70 | 4.84 | +1.04% | |
| 4.45 | 4.82 | 4.43 | 4.79 | +7.64% | |
| 4.23 | 4.50 | 4.05 | 4.45 | +4.95% | |
| 4.27 | 4.38 | 4.06 | 4.24 | -1.62% | |
| 4.17 | 4.33 | 4.07 | 4.31 | +3.86% | |
| 4.15 | 4.26 | 4.06 | 4.15 | +0.24% | |
| 4.21 | 4.25 | 3.97 | 4.14 | -1.66% | |
| 4.30 | 4.32 | 4.15 | 4.21 | -2.55% | |
| 4.28 | 4.37 | 4.21 | 4.32 | -0.23% | |
| 4.34 | 4.35 | 4.25 | 4.33 | 0.00% | |
| 4.40 | 4.43 | 4.25 | 4.33 | -1.81% | |
| 4.33 | 4.47 | 4.18 | 4.41 | +1.38% | |
| 4.33 | 4.44 | 4.07 | 4.35 | +0.23% | |
| 4.39 | 4.56 | 4.28 | 4.34 | +0.93% | |
| 4.47 | 4.53 | 4.25 | 4.30 | -3.59% | |
| 4.28 | 4.58 | 4.28 | 4.46 | +3.72% | |
| 4.54 | 4.64 | 4.26 | 4.30 | -4.66% | |
| 4.58 | 4.60 | 4.43 | 4.51 | -1.31% | |
| 4.66 | 4.66 | 4.41 | 4.57 | -2.14% | |
| 4.30 | 4.69 | 4.29 | 4.67 | +11.19% | |
| 4.35 | 4.36 | 4.19 | 4.20 | -4.33% | |
| 4.44 | 4.50 | 4.36 | 4.39 | -0.23% | |
| 4.70 | 4.70 | 4.39 | 4.40 | -5.98% | |
| 4.82 | 4.82 | 4.57 | 4.68 | -3.70% | |
| 4.77 | 4.88 | 4.71 | 4.86 | +1.89% | |
| 5.01 | 5.04 | 4.75 | 4.77 | -4.41% | |
| 5.23 | 5.35 | 4.96 | 4.99 | -6.20% | |
| 5.26 | 5.39 | 5.12 | 5.32 | +1.53% | |
| 5.33 | 5.42 | 5.01 | 5.24 | -2.06% | |
| 4.82 | 5.40 | 4.64 | 5.35 | +10.54% | |
| 4.56 | 4.89 | 4.54 | 4.84 | +6.84% | |
| 4.48 | 4.64 | 4.15 | 4.53 | +2.26% | |
| 4.64 | 4.80 | 4.31 | 4.43 | -4.94% | |
| 4.24 | 4.80 | 4.15 | 4.66 | +10.17% | |
| 4.14 | 4.35 | 4.02 | 4.23 | +2.42% | |
| 3.94 | 4.20 | 3.89 | 4.13 | +4.82% | |
| 4.12 | 4.24 | 3.86 | 3.94 | -5.74% | |
| 4.38 | 4.49 | 4.14 | 4.18 | -5.43% | |
| 4.17 | 4.49 | 4.10 | 4.42 | +7.80% | |
| 3.75 | 4.14 | 3.72 | 4.10 | +8.47% | |
| 3.90 | 3.98 | 3.76 | 3.78 | -0.79% | |
| 3.77 | 3.85 | 3.47 | 3.81 | 0.00% | |
| 3.92 | 4.02 | 3.79 | 3.81 | -2.81% | |
| 3.79 | 3.94 | 3.71 | 3.92 | +4.81% | |
| 3.86 | 3.95 | 3.67 | 3.74 | -5.32% | |
| 3.85 | 3.99 | 3.77 | 3.95 | +1.28% | |
| 3.99 | 4.00 | 3.81 | 3.90 | -2.74% | |
| 3.61 | 4.01 | 3.54 | 4.01 | +11.08% | |
| 3.83 | 3.83 | 3.56 | 3.61 | -4.75% | |
| 3.98 | 3.98 | 3.71 | 3.79 | -4.05% | |
| 3.96 | 4.10 | 3.75 | 3.95 | -0.25% | |
| 3.80 | 4.04 | 3.65 | 3.96 | +4.21% | |
| 3.56 | 3.86 | 3.54 | 3.80 | +6.74% | |
| 3.87 | 3.87 | 3.53 | 3.56 | -8.48% | |
| 3.85 | 3.90 | 3.59 | 3.89 | -0.26% | |
| 3.37 | 3.92 | 3.34 | 3.90 | +17.47% | |
| 3.60 | 3.69 | 3.26 | 3.32 | -9.78% | |
| 3.68 | 3.80 | 3.55 | 3.68 | +0.55% | |
| 3.64 | 3.78 | 3.50 | 3.66 | +2.81% | |
| 3.20 | 3.66 | 3.10 | 3.56 | +11.60% | |
| 3.20 | 3.28 | 3.06 | 3.19 | +1.27% | |
| 2.91 | 3.38 | 2.86 | 3.15 | +9.76% | |
| 2.94 | 2.94 | 2.78 | 2.87 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the OBIO chart for longer ranges.