Puma Biotechnology Stock Price History
NASDAQ: PBYIHealth CareBiotechnology: Pharmaceutical PreparationsUSD
At close: Oct 9, 4:00 PM ET · Delayed 15 min
PBYI price history at a glance
The price history for Puma Biotechnology (PBYI) on this page begins on April 23, 2012, when the stock closed at $13.00; it most recently closed at $10.29 on October 5, 2026. The highest price in this record is $279.37, reached on August 25, 2014; the latest close is 96.3% below that peak. Across the 13 complete calendar years in the table, PBYI finished higher in 7 and lower in 6. Its best year was 2013 (+438.0%) and its worst was 2018 (-78.4%).
Over roughly 14 years the share price changed -20.8%, a -1.6% compound annual price return (excluding dividends). In the last 12 months alone, PBYI has gained 101.0%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2012
- $279.37
- Date of high
- Aug 25, 2014
- Low since 2012
- $1.60
- Date of low
- May 9, 2022
- 52-week high
- $10.36
- 52-week low
- $4.58
- Last close
- $10.29
PBYI returns
1 week
+8.20%
1 month
+13.70%
3 months
+28.62%
6 months
+32.26%
Year to date
+72.94%
1 year
+100.98%
3 years
+336.02%
5 years
+70.08%
PBYI price return, excluding dividends.
PBYI annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 10.29 | +78.34% |
| 2025 | 5.77 | +95.59% |
| 2024 | 2.95 | -31.87% |
| 2023 | 4.33 | +2.36% |
| 2022 | 4.23 | +39.14% |
| 2021 | 3.04 | -70.37% |
| 2020 | 10.26 | +22.87% |
| 2019 | 8.35 | -60.94% |
| 2018 | 21.38 | -78.37% |
| 2017 | 98.85 | +221.99% |
| 2016 | 30.70 | -60.84% |
| 2015 | 78.40 | -58.71% |
| 2014 | 189.86 | +82.36% |
| 2013 | 104.11 | +438.04% |
| 2012* | 19.35 | +48.85% |
* Partial year: the record begins after the start of 2012; return measured from the first available close.
2026 return is year to date.
PBYI daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 9.97 | 10.35 | 9.85 | 10.29 | +3.21% | |
| 9.75 | 9.99 | 9.45 | 9.97 | +1.63% | |
| 9.45 | 9.96 | 9.41 | 9.81 | +3.26% | |
| 9.72 | 9.80 | 9.43 | 9.50 | -1.76% | |
| 9.45 | 9.78 | 9.33 | 9.67 | +1.68% | |
| 9.94 | 10.00 | 9.50 | 9.51 | -3.35% | |
| 9.84 | 10.08 | 9.77 | 9.84 | -0.91% | |
| 9.85 | 10.10 | 9.74 | 9.93 | +1.53% | |
| 9.77 | 9.90 | 9.68 | 9.78 | -0.41% | |
| 9.77 | 9.89 | 9.54 | 9.82 | +0.51% | |
| 9.90 | 9.90 | 9.65 | 9.77 | -0.51% | |
| 9.25 | 9.87 | 9.02 | 9.82 | +5.82% | |
| 9.82 | 9.90 | 9.08 | 9.28 | -5.50% | |
| 9.65 | 9.98 | 9.57 | 9.82 | +2.40% | |
| 9.66 | 9.75 | 9.51 | 9.59 | -0.10% | |
| 9.52 | 9.66 | 9.44 | 9.60 | +0.84% | |
| 9.39 | 9.61 | 9.39 | 9.52 | +1.38% | |
| 9.26 | 9.40 | 9.16 | 9.39 | +1.51% | |
| 9.15 | 9.39 | 9.05 | 9.25 | +1.20% | |
| 9.10 | 9.23 | 9.03 | 9.14 | +0.22% | |
| 9.26 | 9.28 | 8.93 | 9.12 | -0.55% | |
| 9.01 | 9.22 | 8.90 | 9.17 | +1.33% | |
| 9.31 | 9.45 | 9.01 | 9.05 | -3.62% | |
| 9.25 | 9.57 | 8.85 | 9.39 | -1.68% | |
| 9.40 | 9.64 | 9.31 | 9.55 | +1.49% | |
| 9.72 | 9.72 | 9.37 | 9.41 | -2.89% | |
| 9.40 | 9.74 | 9.28 | 9.69 | +3.64% | |
| 9.11 | 9.59 | 9.11 | 9.35 | +2.63% | |
| 9.02 | 9.20 | 8.78 | 9.11 | +0.55% | |
| 9.24 | 9.26 | 9.02 | 9.06 | -1.95% | |
| 9.01 | 9.30 | 8.95 | 9.24 | +0.87% | |
| 9.31 | 9.31 | 9.04 | 9.16 | -1.72% | |
| 9.22 | 9.38 | 9.17 | 9.32 | +2.19% | |
| 9.30 | 9.30 | 8.99 | 9.12 | -1.30% | |
| 9.20 | 9.48 | 9.07 | 9.24 | +1.43% | |
| 9.45 | 9.45 | 9.03 | 9.11 | -4.00% | |
| 9.33 | 9.51 | 9.25 | 9.49 | +2.71% | |
| 8.80 | 9.34 | 8.80 | 9.24 | +4.76% | |
| 8.80 | 8.99 | 8.62 | 8.82 | -0.11% | |
| 8.84 | 8.89 | 8.53 | 8.83 | +1.38% | |
| 8.93 | 8.97 | 8.65 | 8.71 | -2.13% | |
| 9.01 | 9.23 | 8.78 | 8.90 | +1.48% | |
| 8.77 | 8.91 | 8.48 | 8.77 | +0.92% | |
| 8.96 | 8.96 | 8.55 | 8.69 | -2.47% | |
| 8.15 | 9.40 | 8.12 | 8.91 | +9.73% | |
| 8.02 | 8.16 | 7.86 | 8.12 | +1.63% | |
| 7.84 | 8.08 | 7.82 | 7.99 | +2.44% | |
| 7.71 | 7.83 | 7.63 | 7.80 | +1.43% | |
| 7.98 | 8.00 | 7.41 | 7.69 | -3.03% | |
| 7.85 | 7.94 | 7.63 | 7.93 | +0.51% | |
| 7.79 | 7.95 | 7.73 | 7.89 | +1.02% | |
| 7.96 | 8.05 | 7.77 | 7.81 | -2.01% | |
| 8.00 | 8.23 | 7.67 | 7.97 | -0.25% | |
| 8.04 | 8.18 | 7.99 | 7.99 | +0.13% | |
| 8.05 | 8.11 | 7.94 | 7.98 | -0.37% | |
| 7.75 | 8.03 | 7.61 | 8.01 | +1.78% | |
| 8.52 | 8.58 | 7.83 | 7.87 | -8.28% | |
| 8.34 | 8.75 | 8.33 | 8.58 | +3.37% | |
| 8.45 | 8.54 | 8.14 | 8.30 | -2.70% | |
| 8.28 | 8.64 | 8.25 | 8.53 | +1.55% | |
| 8.39 | 8.66 | 8.35 | 8.40 | -0.12% | |
| 8.28 | 8.54 | 8.14 | 8.41 | +1.57% | |
| 8.10 | 8.43 | 8.01 | 8.28 | +2.48% | |
| 7.95 | 8.18 | 7.72 | 8.08 | +1.00% | |
| 7.90 | 8.14 | 7.70 | 8.00 | +1.27% | |
| 8.05 | 8.37 | 7.67 | 7.90 | -2.83% | |
| 7.90 | 8.21 | 7.85 | 8.13 | +2.14% | |
| 8.23 | 8.24 | 7.78 | 7.96 | -3.16% | |
| 8.26 | 8.44 | 8.08 | 8.22 | -0.48% | |
| 8.00 | 8.32 | 7.99 | 8.26 | +3.38% | |
| 8.07 | 8.16 | 7.86 | 7.99 | -1.48% | |
| 8.11 | 8.25 | 8.10 | 8.11 | -0.98% | |
| 8.08 | 8.24 | 8.03 | 8.19 | +0.99% | |
| 7.67 | 8.23 | 7.67 | 8.11 | +5.74% | |
| 7.94 | 7.97 | 7.62 | 7.67 | -3.52% | |
| 8.10 | 8.41 | 7.81 | 7.95 | -1.12% | |
| 7.64 | 8.08 | 7.57 | 8.04 | +4.96% | |
| 7.60 | 7.87 | 7.56 | 7.66 | +1.32% | |
| 7.36 | 7.59 | 7.26 | 7.56 | +4.56% | |
| 7.16 | 7.31 | 7.10 | 7.23 | +0.84% | |
| 7.12 | 7.20 | 6.96 | 7.17 | +1.41% | |
| 7.38 | 7.45 | 7.00 | 7.07 | -3.55% | |
| 7.26 | 7.33 | 6.98 | 7.33 | +1.38% | |
| 7.03 | 7.33 | 7.00 | 7.23 | +2.99% | |
| 7.07 | 7.17 | 6.98 | 7.02 | -0.43% | |
| 6.94 | 7.09 | 6.85 | 7.05 | +2.92% | |
| 7.15 | 7.17 | 6.80 | 6.85 | -2.56% | |
| 6.99 | 7.08 | 6.92 | 7.03 | +0.29% | |
| 6.81 | 7.05 | 6.78 | 7.01 | +2.94% | |
| 6.96 | 7.04 | 6.79 | 6.81 | -2.44% | |
| 7.05 | 7.12 | 6.89 | 6.98 | -1.97% | |
| 7.09 | 7.13 | 6.84 | 7.12 | -0.70% | |
| 7.23 | 7.23 | 7.08 | 7.17 | -0.97% | |
| 7.33 | 7.37 | 7.16 | 7.24 | -0.96% | |
| 7.28 | 7.45 | 7.25 | 7.31 | +0.55% | |
| 7.15 | 7.30 | 7.05 | 7.27 | +2.68% | |
| 7.19 | 7.19 | 6.94 | 7.08 | +0.43% | |
| 6.89 | 7.09 | 6.85 | 7.05 | +0.86% | |
| 6.84 | 7.04 | 6.77 | 6.99 | +2.64% | |
| 6.74 | 6.83 | 6.60 | 6.81 | 0.00% | |
| 6.88 | 7.03 | 6.76 | 6.81 | -1.59% | |
| 7.10 | 7.16 | 6.90 | 6.92 | -3.76% | |
| 7.18 | 7.25 | 7.11 | 7.19 | +0.28% | |
| 7.00 | 7.17 | 6.96 | 7.17 | +1.27% | |
| 7.16 | 7.33 | 6.84 | 7.08 | -0.84% | |
| 7.50 | 7.54 | 7.08 | 7.14 | -4.67% | |
| 7.17 | 7.87 | 7.08 | 7.49 | +3.17% | |
| 7.52 | 7.52 | 7.02 | 7.26 | -2.55% | |
| 7.44 | 7.70 | 7.40 | 7.45 | +1.36% | |
| 7.59 | 7.70 | 7.11 | 7.35 | -2.39% | |
| 7.46 | 7.70 | 7.41 | 7.53 | +0.53% | |
| 7.52 | 7.55 | 7.33 | 7.49 | -0.27% | |
| 7.48 | 7.66 | 7.45 | 7.51 | +0.40% | |
| 7.52 | 7.56 | 7.43 | 7.48 | -0.80% | |
| 7.53 | 7.73 | 7.50 | 7.54 | +0.40% | |
| 7.50 | 7.70 | 7.44 | 7.51 | -0.40% | |
| 7.41 | 7.56 | 7.09 | 7.54 | +1.89% | |
| 7.41 | 7.61 | 7.38 | 7.40 | -0.40% | |
| 7.30 | 7.48 | 7.27 | 7.43 | +2.34% | |
| 7.41 | 7.41 | 7.17 | 7.26 | -1.49% | |
| 7.45 | 7.50 | 7.32 | 7.37 | -1.34% | |
| 7.41 | 7.57 | 7.23 | 7.47 | +3.18% | |
| 7.46 | 7.61 | 7.20 | 7.24 | -3.21% | |
| 7.56 | 7.65 | 7.44 | 7.48 | -1.19% | |
| 7.58 | 7.73 | 7.46 | 7.57 | 0.00% | |
| 7.76 | 7.85 | 7.55 | 7.57 | -2.70% | |
| 7.81 | 7.90 | 7.58 | 7.78 | -0.26% | |
| 7.42 | 7.85 | 7.38 | 7.80 | +3.86% | |
| 7.17 | 7.54 | 7.11 | 7.51 | +7.75% | |
| 6.84 | 7.02 | 6.61 | 6.97 | +1.16% | |
| 6.92 | 7.02 | 6.70 | 6.89 | -0.14% | |
| 6.61 | 6.99 | 6.54 | 6.90 | +2.07% | |
| 6.47 | 6.85 | 6.46 | 6.76 | +5.79% | |
| 6.21 | 6.43 | 6.15 | 6.39 | +4.24% | |
| 6.12 | 6.23 | 6.05 | 6.13 | +0.82% | |
| 6.22 | 6.29 | 6.00 | 6.08 | -3.03% | |
| 6.21 | 6.45 | 6.20 | 6.27 | -0.95% | |
| 6.34 | 6.52 | 6.30 | 6.33 | +1.12% | |
| 6.10 | 6.34 | 6.10 | 6.26 | +0.16% | |
| 6.24 | 6.32 | 6.12 | 6.25 | +2.12% | |
| 6.14 | 6.17 | 6.07 | 6.12 | -0.49% | |
| 5.95 | 6.26 | 5.95 | 6.15 | +2.50% | |
| 6.09 | 6.13 | 5.95 | 6.00 | -2.28% | |
| 6.04 | 6.18 | 6.04 | 6.14 | +1.15% | |
| 6.00 | 6.13 | 5.97 | 6.07 | +2.88% | |
| 5.94 | 6.02 | 5.85 | 5.90 | +0.34% | |
| 5.88 | 5.98 | 5.85 | 5.88 | -2.00% | |
| 6.10 | 6.15 | 5.86 | 6.00 | -0.99% | |
| 6.17 | 6.35 | 5.98 | 6.06 | -2.57% | |
| 5.98 | 6.24 | 5.86 | 6.22 | +2.81% | |
| 6.19 | 6.22 | 5.96 | 6.05 | -2.89% | |
| 6.33 | 6.39 | 6.14 | 6.23 | -2.66% | |
| 6.20 | 6.75 | 6.11 | 6.40 | +3.06% | |
| 6.34 | 6.34 | 6.10 | 6.21 | -3.27% | |
| 5.51 | 6.45 | 5.50 | 6.42 | +12.63% | |
| 6.30 | 6.86 | 5.51 | 5.70 | -25.00% | |
| 7.68 | 7.68 | 7.35 | 7.60 | -1.04% | |
| 7.51 | 7.68 | 7.43 | 7.68 | +2.54% | |
| 7.13 | 7.58 | 7.05 | 7.49 | +5.34% | |
| 6.82 | 7.15 | 6.77 | 7.11 | +4.10% | |
| 6.78 | 6.86 | 6.65 | 6.83 | +0.59% | |
| 6.63 | 6.84 | 6.50 | 6.79 | +1.65% | |
| 6.75 | 6.91 | 6.64 | 6.68 | -1.04% | |
| 6.82 | 6.90 | 6.62 | 6.75 | -1.03% | |
| 6.79 | 6.99 | 6.70 | 6.82 | +0.29% | |
| 6.67 | 6.83 | 6.48 | 6.80 | +2.41% | |
| 6.63 | 6.69 | 6.37 | 6.64 | +0.45% | |
| 6.83 | 6.98 | 6.59 | 6.61 | -3.92% | |
| 6.88 | 6.98 | 6.76 | 6.88 | -0.86% | |
| 6.88 | 7.05 | 6.85 | 6.94 | +2.21% | |
| 7.01 | 7.29 | 6.75 | 6.79 | -4.37% | |
| 7.14 | 7.20 | 6.91 | 7.10 | 0.00% | |
| 6.79 | 7.14 | 6.79 | 7.10 | +4.11% | |
| 6.44 | 6.93 | 6.43 | 6.82 | +5.25% | |
| 6.39 | 6.50 | 6.27 | 6.48 | +0.78% | |
| 6.33 | 6.49 | 6.33 | 6.43 | +1.74% | |
| 6.60 | 6.64 | 6.26 | 6.32 | -3.81% | |
| 6.43 | 6.64 | 6.43 | 6.57 | +2.18% | |
| 6.39 | 6.47 | 6.27 | 6.43 | +0.16% | |
| 6.82 | 6.90 | 6.34 | 6.42 | -6.41% | |
| 6.94 | 7.21 | 6.55 | 6.86 | -0.44% | |
| 6.64 | 6.90 | 6.55 | 6.89 | +4.39% | |
| 6.34 | 6.66 | 6.29 | 6.60 | +3.61% | |
| 6.38 | 6.48 | 6.34 | 6.37 | -0.16% | |
| 6.42 | 6.46 | 6.35 | 6.38 | -0.62% | |
| 6.23 | 6.44 | 6.15 | 6.42 | +2.88% | |
| 6.28 | 6.30 | 6.11 | 6.24 | -0.64% | |
| 6.10 | 6.30 | 6.05 | 6.28 | +2.78% | |
| 6.10 | 6.26 | 6.08 | 6.11 | -1.45% | |
| 6.09 | 6.29 | 5.97 | 6.20 | +1.81% | |
| 5.90 | 6.11 | 5.79 | 6.09 | +3.92% | |
| 5.93 | 5.96 | 5.77 | 5.86 | -1.35% | |
| 5.80 | 6.00 | 5.75 | 5.94 | +2.95% | |
| 5.97 | 6.00 | 5.64 | 5.77 | -3.03% | |
| 6.01 | 6.05 | 5.94 | 5.95 | -1.00% | |
| 6.10 | 6.15 | 5.99 | 6.01 | -1.31% | |
| 6.16 | 6.27 | 5.97 | 6.09 | -1.14% | |
| 6.00 | 6.22 | 5.81 | 6.16 | +3.36% | |
| 5.91 | 6.00 | 5.82 | 5.96 | +0.85% | |
| 5.79 | 5.99 | 5.72 | 5.91 | +1.37% | |
| 5.70 | 5.94 | 5.65 | 5.83 | +3.55% | |
| 5.61 | 5.69 | 5.51 | 5.63 | +0.18% | |
| 5.62 | 5.73 | 5.54 | 5.62 | +0.72% | |
| 5.66 | 5.67 | 5.48 | 5.58 | -1.59% | |
| 5.82 | 5.90 | 5.62 | 5.67 | -2.58% | |
| 5.87 | 5.92 | 5.73 | 5.82 | -0.68% | |
| 5.72 | 5.87 | 5.67 | 5.86 | +2.27% | |
| 5.60 | 5.75 | 5.58 | 5.73 | +2.50% | |
| 5.50 | 5.67 | 5.44 | 5.59 | +1.27% | |
| 5.42 | 5.65 | 5.33 | 5.52 | +2.22% | |
| 5.33 | 5.44 | 5.19 | 5.40 | +1.89% | |
| 5.28 | 5.33 | 5.17 | 5.30 | +0.19% | |
| 5.16 | 5.32 | 5.16 | 5.29 | +1.93% | |
| 4.90 | 5.24 | 4.84 | 5.19 | +6.57% | |
| 4.95 | 5.01 | 4.84 | 4.87 | -1.81% | |
| 4.90 | 4.99 | 4.90 | 4.96 | -1.78% | |
| 5.06 | 5.11 | 4.99 | 5.05 | 0.00% | |
| 4.93 | 5.09 | 4.90 | 5.05 | +2.02% | |
| 5.02 | 5.08 | 4.89 | 4.95 | -0.60% | |
| 4.90 | 5.10 | 4.89 | 4.98 | +1.84% | |
| 4.85 | 5.03 | 4.85 | 4.89 | +1.03% | |
| 4.95 | 5.00 | 4.80 | 4.84 | -1.02% | |
| 5.03 | 5.06 | 4.88 | 4.89 | -3.36% | |
| 4.97 | 5.09 | 4.86 | 5.06 | +2.02% | |
| 4.85 | 5.10 | 4.85 | 4.96 | +1.43% | |
| 4.85 | 5.02 | 4.76 | 4.89 | -1.21% | |
| 4.93 | 4.97 | 4.81 | 4.95 | -0.80% | |
| 5.11 | 5.16 | 4.89 | 4.99 | -3.85% | |
| 4.75 | 5.20 | 4.58 | 5.19 | +9.73% | |
| 5.99 | 6.12 | 4.70 | 4.73 | -21.04% | |
| 5.33 | 6.04 | 5.04 | 5.99 | +22.24% | |
| 5.01 | 5.09 | 4.88 | 4.90 | -1.01% | |
| 4.91 | 5.07 | 4.80 | 4.95 | +1.02% | |
| 5.03 | 5.10 | 4.86 | 4.90 | -2.78% | |
| 5.13 | 5.22 | 5.00 | 5.04 | -1.18% | |
| 5.43 | 5.43 | 5.10 | 5.10 | -6.59% | |
| 5.16 | 5.52 | 5.15 | 5.46 | +5.81% | |
| 5.22 | 5.32 | 5.14 | 5.16 | -1.71% | |
| 5.27 | 5.30 | 5.20 | 5.25 | -0.38% | |
| 5.61 | 5.61 | 5.23 | 5.27 | +0.76% | |
| 5.09 | 5.29 | 5.09 | 5.23 | +3.77% | |
| 5.23 | 5.24 | 5.00 | 5.04 | -3.63% | |
| 5.19 | 5.28 | 5.10 | 5.23 | +1.16% | |
| 5.44 | 5.44 | 5.06 | 5.17 | -5.14% | |
| 5.54 | 5.59 | 5.34 | 5.45 | -0.37% | |
| 5.38 | 5.57 | 5.34 | 5.47 | +1.11% | |
| 5.55 | 5.75 | 5.33 | 5.41 | -1.64% | |
| 5.34 | 5.50 | 5.29 | 5.50 | +3.58% | |
| 5.25 | 5.50 | 5.16 | 5.31 | +0.38% | |
| 5.16 | 5.34 | 5.13 | 5.29 | +3.32% | |
| 5.24 | 5.42 | 5.11 | 5.12 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the PBYI chart for longer ranges.