Praxis Precision Medicines Stock Price History
NASDAQ: PRAXHealth CareBiotechnology: Pharmaceutical PreparationsUSD
259.86-3.69 (-1.40%)
At close: Oct 9, 4:00 PM ET · Delayed 15 min
PRAX price history at a glance
The price history for Praxis Precision Medicines (PRAX) on this page begins on October 12, 2020, when the stock closed at $417.00; it most recently closed at $259.86 on October 5, 2026. The highest price in this record is $914.27, reached on January 4, 2021; the latest close is 71.6% below that peak. Across the 5 complete calendar years in the table, PRAX finished higher in 2 and lower in 3. Its best year was 2024 (+263.2%) and its worst was 2022 (-87.9%).
Over roughly 6 years the share price changed -37.7%, a -7.6% compound annual price return (excluding dividends). In the last 12 months alone, PRAX has gained 374.5%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2020
- $914.27
- Date of high
- Jan 4, 2021
- Low since 2020
- $11.85
- Date of low
- Mar 27, 2023
- 52-week high
- $392.70
- 52-week low
- $50.56
- IPO year
- 2020
- Last close
- $259.86
PRAX returns
1 week
-12.06%
1 month
-24.74%
3 months
-20.04%
6 months
-17.80%
Year to date
-11.83%
1 year
+374.54%
3 years
+1173.82%
5 years
-13.42%
PRAX price return, excluding dividends.
PRAX annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 259.86 | -9.27% |
| 2025 | 286.40 | +253.89% |
| 2024 | 80.93 | +263.24% |
| 2023 | 22.28 | -37.59% |
| 2022 | 35.70 | -87.92% |
| 2021 | 295.50 | -64.19% |
| 2020* | 825.30 | +97.91% |
* Partial year: the record begins after the start of 2020; return measured from the first available close.
2026 return is year to date.
PRAX daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 266.91 | 267.56 | 259.00 | 259.86 | -1.40% | |
| 273.74 | 273.87 | 260.14 | 263.55 | -5.20% | |
| 277.16 | 285.63 | 271.28 | 278.02 | -0.76% | |
| 289.47 | 289.47 | 272.17 | 280.14 | -1.21% | |
| 299.12 | 299.12 | 278.01 | 283.56 | -4.04% | |
| 290.13 | 298.56 | 286.00 | 295.51 | +3.00% | |
| 287.83 | 292.47 | 282.00 | 286.91 | -1.48% | |
| 284.65 | 296.27 | 282.00 | 291.23 | +3.64% | |
| 283.28 | 289.16 | 278.39 | 281.00 | -1.63% | |
| 280.78 | 292.18 | 277.91 | 285.65 | +1.73% | |
| 284.45 | 289.05 | 278.60 | 280.78 | -0.36% | |
| 281.18 | 286.38 | 276.34 | 281.79 | -0.12% | |
| 301.37 | 304.94 | 275.89 | 282.12 | -6.16% | |
| 300.19 | 312.46 | 298.40 | 300.65 | +0.60% | |
| 301.69 | 305.79 | 295.22 | 298.87 | -0.03% | |
| 312.76 | 314.01 | 295.71 | 298.95 | -3.71% | |
| 313.65 | 318.00 | 306.50 | 310.47 | +0.48% | |
| 315.22 | 321.95 | 303.88 | 308.99 | -1.25% | |
| 330.42 | 333.06 | 311.98 | 312.90 | -5.34% | |
| 337.67 | 341.71 | 328.95 | 330.55 | -1.20% | |
| 340.00 | 348.00 | 334.00 | 334.58 | -1.18% | |
| 339.60 | 347.40 | 337.31 | 338.57 | -1.95% | |
| 352.80 | 360.61 | 344.03 | 345.30 | -2.04% | |
| 342.25 | 356.29 | 339.50 | 352.48 | +0.19% | |
| 352.99 | 357.50 | 349.82 | 351.81 | -0.94% | |
| 355.31 | 363.14 | 351.15 | 355.15 | -0.66% | |
| 358.42 | 365.71 | 347.01 | 357.50 | +1.15% | |
| 350.00 | 355.49 | 347.86 | 353.44 | +0.90% | |
| 343.00 | 351.72 | 333.46 | 350.30 | +1.61% | |
| 363.40 | 367.70 | 344.69 | 344.75 | -6.28% | |
| 375.77 | 377.50 | 366.88 | 367.85 | -2.52% | |
| 368.45 | 383.30 | 362.79 | 377.37 | +2.54% | |
| 374.10 | 382.38 | 361.99 | 368.02 | -0.00% | |
| 375.94 | 375.94 | 360.19 | 368.03 | -2.10% | |
| 370.35 | 387.99 | 365.37 | 375.94 | +3.12% | |
| 392.70 | 392.70 | 361.16 | 364.58 | -5.60% | |
| 377.00 | 392.45 | 365.64 | 386.19 | +4.42% | |
| 369.40 | 375.00 | 365.05 | 369.84 | -1.74% | |
| 371.97 | 391.64 | 370.03 | 376.38 | +2.61% | |
| 365.02 | 368.40 | 355.11 | 366.81 | -0.45% | |
| 388.00 | 388.00 | 367.57 | 368.46 | -4.63% | |
| 375.00 | 386.66 | 373.09 | 386.33 | +4.22% | |
| 367.50 | 372.00 | 361.37 | 370.68 | +1.01% | |
| 358.72 | 368.31 | 354.70 | 366.96 | +1.72% | |
| 372.26 | 381.98 | 347.87 | 360.76 | -2.54% | |
| 350.47 | 382.54 | 343.73 | 370.16 | +15.95% | |
| 315.00 | 320.68 | 308.17 | 319.23 | +2.95% | |
| 307.59 | 313.06 | 301.40 | 310.07 | +1.49% | |
| 300.92 | 307.56 | 292.89 | 305.51 | -0.75% | |
| 308.74 | 310.15 | 293.22 | 307.83 | +0.03% | |
| 298.48 | 311.60 | 293.49 | 307.75 | +5.75% | |
| 302.34 | 303.75 | 287.94 | 291.03 | -1.62% | |
| 316.96 | 316.96 | 290.09 | 295.81 | -6.33% | |
| 325.30 | 330.00 | 315.70 | 315.80 | -2.92% | |
| 322.29 | 327.51 | 314.62 | 325.30 | +0.90% | |
| 308.00 | 323.25 | 305.00 | 322.40 | +3.30% | |
| 311.52 | 317.45 | 308.06 | 312.10 | -1.82% | |
| 306.11 | 320.60 | 304.00 | 317.87 | +4.41% | |
| 315.00 | 325.66 | 304.19 | 304.43 | -3.17% | |
| 299.16 | 322.26 | 299.16 | 314.41 | +2.01% | |
| 314.53 | 318.77 | 303.28 | 308.20 | -3.21% | |
| 321.46 | 325.41 | 312.60 | 318.42 | -2.83% | |
| 318.77 | 330.17 | 313.58 | 327.68 | +4.17% | |
| 320.00 | 327.26 | 308.24 | 314.56 | -3.21% | |
| 331.31 | 343.11 | 307.88 | 324.99 | -2.44% | |
| 332.07 | 340.32 | 328.31 | 333.12 | +0.04% | |
| 323.47 | 336.72 | 317.04 | 332.99 | +2.79% | |
| 315.11 | 327.61 | 307.00 | 323.95 | +3.33% | |
| 319.04 | 324.83 | 312.24 | 313.50 | -1.58% | |
| 319.82 | 329.27 | 310.10 | 318.52 | -0.34% | |
| 330.89 | 337.72 | 312.05 | 319.60 | -4.54% | |
| 340.92 | 349.67 | 324.62 | 334.79 | -4.50% | |
| 323.82 | 354.17 | 315.83 | 350.56 | +6.95% | |
| 326.08 | 334.27 | 314.00 | 327.79 | -0.02% | |
| 306.03 | 328.68 | 304.97 | 327.86 | +6.12% | |
| 303.93 | 316.59 | 302.50 | 308.94 | +1.17% | |
| 298.50 | 308.01 | 296.36 | 305.37 | +0.65% | |
| 292.56 | 305.00 | 285.00 | 303.39 | +7.47% | |
| 280.60 | 289.67 | 274.16 | 282.31 | +4.56% | |
| 259.08 | 277.00 | 259.08 | 270.01 | +4.96% | |
| 264.93 | 274.09 | 255.39 | 257.25 | -2.76% | |
| 270.90 | 274.98 | 262.97 | 264.54 | -0.77% | |
| 247.26 | 269.40 | 247.26 | 266.58 | +7.50% | |
| 241.01 | 252.78 | 239.41 | 247.98 | +3.04% | |
| 248.60 | 257.91 | 238.77 | 240.66 | -3.86% | |
| 258.10 | 266.60 | 244.16 | 250.33 | -1.15% | |
| 258.34 | 266.60 | 247.59 | 253.25 | -0.30% | |
| 264.18 | 271.40 | 252.46 | 254.00 | -4.06% | |
| 275.90 | 279.98 | 263.25 | 264.75 | -5.08% | |
| 259.18 | 279.80 | 258.32 | 278.93 | +8.08% | |
| 307.01 | 321.75 | 255.81 | 258.08 | -23.00% | |
| 349.44 | 349.44 | 332.18 | 335.16 | -4.23% | |
| 352.63 | 355.00 | 338.07 | 349.97 | -0.75% | |
| 356.00 | 357.36 | 345.54 | 352.63 | -1.26% | |
| 346.29 | 366.52 | 346.29 | 357.13 | +1.86% | |
| 344.00 | 357.68 | 339.52 | 350.60 | +2.05% | |
| 350.43 | 353.00 | 342.98 | 343.56 | -2.00% | |
| 329.96 | 352.73 | 329.96 | 350.56 | +4.45% | |
| 324.17 | 338.27 | 321.74 | 335.61 | +4.68% | |
| 316.17 | 325.89 | 306.79 | 320.61 | +0.02% | |
| 344.31 | 344.31 | 314.11 | 320.53 | -6.44% | |
| 337.80 | 350.45 | 334.00 | 342.58 | -0.85% | |
| 347.29 | 353.99 | 334.33 | 345.52 | -0.38% | |
| 343.20 | 358.76 | 330.76 | 346.84 | +1.06% | |
| 329.15 | 343.92 | 321.20 | 343.20 | +3.43% | |
| 333.53 | 341.26 | 327.89 | 331.81 | +0.54% | |
| 331.00 | 341.75 | 326.16 | 330.02 | -0.98% | |
| 349.00 | 353.00 | 317.92 | 333.28 | -1.42% | |
| 335.23 | 340.21 | 323.30 | 338.07 | +1.43% | |
| 339.89 | 344.99 | 324.32 | 333.30 | -1.28% | |
| 322.43 | 339.30 | 320.50 | 337.61 | +4.14% | |
| 316.70 | 335.00 | 310.01 | 324.20 | +1.68% | |
| 327.64 | 331.34 | 316.60 | 318.83 | -1.35% | |
| 319.00 | 325.09 | 315.46 | 323.19 | +0.39% | |
| 333.79 | 349.01 | 319.40 | 321.92 | -2.74% | |
| 344.16 | 348.30 | 327.21 | 330.99 | -4.01% | |
| 330.50 | 345.40 | 322.02 | 344.82 | +4.62% | |
| 339.69 | 344.00 | 327.66 | 329.60 | -2.28% | |
| 344.00 | 348.98 | 334.18 | 337.29 | -1.04% | |
| 340.64 | 345.43 | 331.33 | 340.84 | -0.51% | |
| 342.68 | 349.49 | 339.99 | 342.57 | +0.02% | |
| 326.26 | 346.35 | 324.87 | 342.50 | +6.90% | |
| 336.02 | 340.42 | 314.15 | 320.39 | -5.75% | |
| 348.04 | 350.00 | 330.00 | 339.93 | -1.07% | |
| 325.95 | 352.78 | 325.95 | 343.60 | +8.39% | |
| 320.00 | 332.99 | 316.50 | 317.00 | +0.27% | |
| 325.17 | 327.56 | 312.89 | 316.14 | -1.28% | |
| 320.00 | 323.11 | 312.73 | 320.24 | +0.01% | |
| 323.58 | 327.00 | 311.01 | 320.22 | +4.41% | |
| 309.41 | 310.00 | 300.57 | 306.69 | -1.10% | |
| 318.76 | 323.69 | 306.36 | 310.11 | -0.09% | |
| 308.97 | 321.94 | 308.51 | 310.38 | -2.79% | |
| 329.15 | 338.31 | 318.78 | 319.28 | -0.90% | |
| 289.20 | 325.20 | 279.27 | 322.19 | +16.55% | |
| 291.59 | 296.05 | 271.95 | 276.44 | -4.71% | |
| 302.68 | 305.94 | 288.59 | 290.10 | -4.16% | |
| 311.92 | 315.00 | 300.91 | 302.69 | -2.96% | |
| 296.81 | 314.00 | 296.81 | 311.92 | +5.86% | |
| 289.98 | 299.30 | 285.55 | 294.65 | +0.18% | |
| 298.40 | 312.29 | 293.57 | 294.11 | -1.41% | |
| 295.67 | 306.58 | 294.56 | 298.31 | +0.27% | |
| 285.04 | 302.46 | 285.00 | 297.50 | +3.02% | |
| 299.21 | 302.36 | 288.27 | 288.79 | -4.81% | |
| 304.04 | 313.00 | 302.04 | 303.38 | -0.53% | |
| 301.46 | 311.00 | 301.29 | 305.00 | +3.76% | |
| 303.37 | 316.06 | 290.81 | 293.95 | -3.11% | |
| 292.50 | 305.27 | 288.00 | 303.37 | +2.16% | |
| 306.48 | 318.72 | 296.25 | 296.97 | -4.18% | |
| 305.79 | 323.87 | 305.49 | 309.91 | +0.29% | |
| 313.03 | 327.54 | 291.17 | 309.01 | -0.55% | |
| 303.32 | 316.46 | 303.01 | 310.71 | +0.04% | |
| 319.79 | 320.71 | 303.45 | 310.58 | -4.47% | |
| 321.78 | 332.57 | 319.28 | 325.11 | +2.17% | |
| 318.50 | 329.53 | 314.64 | 318.22 | -3.74% | |
| 325.30 | 342.51 | 325.00 | 330.59 | -1.83% | |
| 334.93 | 341.16 | 331.53 | 336.75 | -1.09% | |
| 347.55 | 354.87 | 334.76 | 340.47 | -2.04% | |
| 343.40 | 354.43 | 341.00 | 347.55 | +1.41% | |
| 345.48 | 356.00 | 338.81 | 342.71 | +0.07% | |
| 335.00 | 348.67 | 332.31 | 342.46 | +2.14% | |
| 332.52 | 349.32 | 314.39 | 335.28 | +1.11% | |
| 315.00 | 333.84 | 293.01 | 331.61 | +0.81% | |
| 329.25 | 334.61 | 326.57 | 328.93 | +0.27% | |
| 315.22 | 330.09 | 314.35 | 328.04 | +3.40% | |
| 332.74 | 333.53 | 315.42 | 317.25 | -4.71% | |
| 323.99 | 335.75 | 317.83 | 332.92 | +2.98% | |
| 321.83 | 324.79 | 302.00 | 323.29 | +0.88% | |
| 325.40 | 326.88 | 315.42 | 320.48 | +0.29% | |
| 317.73 | 328.60 | 310.53 | 319.54 | -0.01% | |
| 310.84 | 321.57 | 309.26 | 319.57 | +4.56% | |
| 301.51 | 311.54 | 297.27 | 305.62 | +0.75% | |
| 311.75 | 313.00 | 288.57 | 303.34 | -2.31% | |
| 311.50 | 325.22 | 306.00 | 310.52 | +0.46% | |
| 307.43 | 318.18 | 304.03 | 309.11 | -1.56% | |
| 315.00 | 319.13 | 309.12 | 314.00 | -0.09% | |
| 309.45 | 319.56 | 304.08 | 314.28 | +1.41% | |
| 323.00 | 323.40 | 308.74 | 309.92 | -1.53% | |
| 290.00 | 315.91 | 289.50 | 314.75 | +7.04% | |
| 305.98 | 306.00 | 289.72 | 294.04 | -5.67% | |
| 304.20 | 318.00 | 298.38 | 311.71 | +2.41% | |
| 312.79 | 319.58 | 299.19 | 304.38 | -2.63% | |
| 322.82 | 326.83 | 305.69 | 312.60 | -3.54% | |
| 307.20 | 326.06 | 307.20 | 324.08 | +2.15% | |
| 299.07 | 326.91 | 295.47 | 317.25 | +6.55% | |
| 300.32 | 305.68 | 294.29 | 297.74 | -0.24% | |
| 282.95 | 306.16 | 279.04 | 298.46 | +6.28% | |
| 276.00 | 281.56 | 270.00 | 280.83 | +1.85% | |
| 283.00 | 283.04 | 266.93 | 275.74 | -4.41% | |
| 291.96 | 305.21 | 285.99 | 288.45 | -2.01% | |
| 285.22 | 302.34 | 282.00 | 294.38 | +0.60% | |
| 274.78 | 295.01 | 271.53 | 292.63 | +7.23% | |
| 271.29 | 281.21 | 268.78 | 272.90 | -1.45% | |
| 288.13 | 288.13 | 272.14 | 276.92 | -3.31% | |
| 290.51 | 294.45 | 281.60 | 286.40 | -2.83% | |
| 296.88 | 300.99 | 293.50 | 294.74 | -0.77% | |
| 304.00 | 305.49 | 285.95 | 297.02 | -2.48% | |
| 317.72 | 317.72 | 298.00 | 304.58 | +13.25% | |
| 271.03 | 273.88 | 266.51 | 268.95 | -2.11% | |
| 279.48 | 279.48 | 270.01 | 274.76 | -0.35% | |
| 277.91 | 286.50 | 274.07 | 275.73 | -1.67% | |
| 273.00 | 285.85 | 268.57 | 280.40 | +2.74% | |
| 271.65 | 279.14 | 267.51 | 272.92 | +1.36% | |
| 270.31 | 275.31 | 262.31 | 269.26 | +1.28% | |
| 270.72 | 276.50 | 263.53 | 265.86 | -3.15% | |
| 270.98 | 282.00 | 269.77 | 274.51 | -0.68% | |
| 272.46 | 282.99 | 270.55 | 276.40 | +2.83% | |
| 263.98 | 274.35 | 263.84 | 268.80 | +0.57% | |
| 261.40 | 271.69 | 252.20 | 267.28 | +2.18% | |
| 255.71 | 265.00 | 251.00 | 261.58 | +1.34% | |
| 271.00 | 278.44 | 256.50 | 258.13 | -4.74% | |
| 256.92 | 278.00 | 256.71 | 270.98 | +9.27% | |
| 241.00 | 277.44 | 240.41 | 247.99 | +30.54% | |
| 185.87 | 199.53 | 180.93 | 189.97 | +2.05% | |
| 181.00 | 190.76 | 180.46 | 186.15 | +3.93% | |
| 185.12 | 190.40 | 171.20 | 179.12 | -2.95% | |
| 193.44 | 195.58 | 183.17 | 184.56 | -6.06% | |
| 190.36 | 199.47 | 188.01 | 196.46 | +4.20% | |
| 183.71 | 190.54 | 181.76 | 188.54 | +2.33% | |
| 191.59 | 192.29 | 183.55 | 184.25 | -3.46% | |
| 172.55 | 192.70 | 167.32 | 190.86 | +12.40% | |
| 163.07 | 174.07 | 160.11 | 169.80 | +3.48% | |
| 191.00 | 197.50 | 163.11 | 164.09 | -13.33% | |
| 188.08 | 191.76 | 180.53 | 189.32 | +2.82% | |
| 194.82 | 195.58 | 181.74 | 184.13 | -6.81% | |
| 185.84 | 198.43 | 185.32 | 197.58 | +5.99% | |
| 178.08 | 197.55 | 175.79 | 186.42 | +4.68% | |
| 184.15 | 184.15 | 177.07 | 178.08 | -3.01% | |
| 181.48 | 188.53 | 180.48 | 183.61 | +0.03% | |
| 168.81 | 185.67 | 166.00 | 183.56 | +9.33% | |
| 169.90 | 174.99 | 160.38 | 167.89 | -0.20% | |
| 170.17 | 172.00 | 159.74 | 168.22 | -2.40% | |
| 164.01 | 176.36 | 160.90 | 172.35 | +4.68% | |
| 169.14 | 173.48 | 154.45 | 164.64 | -4.14% | |
| 180.70 | 186.72 | 171.74 | 171.75 | -5.63% | |
| 180.49 | 186.68 | 167.03 | 181.99 | -8.44% | |
| 198.16 | 201.99 | 195.50 | 198.76 | -1.11% | |
| 191.39 | 206.71 | 191.39 | 201.00 | +2.68% | |
| 198.29 | 198.29 | 191.65 | 195.76 | -1.79% | |
| 183.52 | 200.00 | 182.00 | 199.33 | +7.20% | |
| 174.55 | 187.72 | 174.55 | 185.94 | +6.88% | |
| 180.93 | 181.00 | 168.16 | 173.97 | -2.27% | |
| 185.00 | 187.38 | 177.52 | 178.01 | -3.48% | |
| 189.71 | 192.96 | 178.02 | 184.43 | -2.94% | |
| 178.88 | 191.92 | 176.61 | 190.02 | +8.54% | |
| 190.00 | 190.27 | 164.75 | 175.07 | -7.85% | |
| 178.90 | 203.58 | 178.14 | 189.99 | +16.77% | |
| 158.29 | 205.89 | 156.41 | 162.71 | +183.71% | |
| 52.62 | 57.63 | 52.62 | 57.35 | +9.20% | |
| 51.81 | 53.30 | 50.56 | 52.52 | +0.34% | |
| 53.52 | 53.90 | 51.37 | 52.34 | -1.73% | |
| 54.86 | 55.11 | 51.99 | 53.26 | -2.74% | |
| 53.98 | 55.04 | 52.25 | 54.76 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the PRAX chart for longer ranges.