Prelude Therapeutics Stock Price History
NASDAQ: PRLDHealth CareBiotechnology: Pharmaceutical PreparationsUSD
3.89+0.01 (+0.26%)
At close: Oct 9, 4:00 PM ET · Delayed 15 min
PRLD price history at a glance
The price history for Prelude Therapeutics (PRLD) on this page begins on September 21, 2020, when the stock closed at $26.20; it most recently closed at $3.89 on October 5, 2026. The highest price in this record is $95.38, reached on February 8, 2021; the latest close is 95.9% below that peak. Across the 5 complete calendar years in the table, PRLD finished higher in 1 and lower in 4. Its best year was 2025 (+96.4%) and its worst was 2021 (-82.6%).
Over roughly 6 years the share price changed -85.2%, a -27.1% compound annual price return (excluding dividends). In the last 12 months alone, PRLD has gained 177.9%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2020
- $95.38
- Date of high
- Feb 8, 2021
- Low since 2020
- $0.61
- Date of low
- Apr 7, 2025
- 52-week high
- $6.83
- 52-week low
- $1.16
- IPO year
- 2020
- Last close
- $3.89
PRLD returns
1 week
+5.99%
1 month
-23.58%
3 months
-19.04%
6 months
-4.66%
Year to date
+34.14%
1 year
+177.86%
3 years
+60.74%
5 years
-76.08%
PRLD price return, excluding dividends.
PRLD annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 3.89 | +42.49% |
| 2025 | 2.73 | +96.40% |
| 2024 | 1.39 | -67.45% |
| 2023 | 4.27 | -29.30% |
| 2022 | 6.04 | -51.49% |
| 2021 | 12.45 | -82.60% |
| 2020* | 71.55 | +173.09% |
* Partial year: the record begins after the start of 2020; return measured from the first available close.
2026 return is year to date.
PRLD daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 3.87 | 4.03 | 3.85 | 3.89 | +0.26% | |
| 3.77 | 3.95 | 3.67 | 3.88 | +1.31% | |
| 3.75 | 3.93 | 3.69 | 3.83 | +0.52% | |
| 3.78 | 3.82 | 3.68 | 3.81 | +1.06% | |
| 3.68 | 3.81 | 3.55 | 3.77 | +2.72% | |
| 3.75 | 3.82 | 3.63 | 3.67 | -3.17% | |
| 3.90 | 3.94 | 3.59 | 3.79 | -3.07% | |
| 4.02 | 4.02 | 3.86 | 3.91 | -1.26% | |
| 3.95 | 4.00 | 3.83 | 3.96 | +1.28% | |
| 3.85 | 3.98 | 3.72 | 3.91 | +0.90% | |
| 4.00 | 4.05 | 3.83 | 3.88 | -2.88% | |
| 4.31 | 4.32 | 3.86 | 3.99 | -7.42% | |
| 4.85 | 4.87 | 4.16 | 4.31 | -11.13% | |
| 4.70 | 4.91 | 4.63 | 4.85 | +3.19% | |
| 4.88 | 4.91 | 4.69 | 4.70 | -3.49% | |
| 4.58 | 4.87 | 4.51 | 4.87 | +6.56% | |
| 4.79 | 4.91 | 4.49 | 4.57 | +2.24% | |
| 4.55 | 4.65 | 4.36 | 4.47 | -1.11% | |
| 4.56 | 4.58 | 4.40 | 4.52 | -1.53% | |
| 4.60 | 4.68 | 4.50 | 4.59 | 0.00% | |
| 4.72 | 4.75 | 4.56 | 4.59 | -1.71% | |
| 5.04 | 5.22 | 4.64 | 4.67 | -8.25% | |
| 5.25 | 5.34 | 5.06 | 5.09 | -3.96% | |
| 5.38 | 5.46 | 5.19 | 5.30 | -2.93% | |
| 5.19 | 5.52 | 5.19 | 5.46 | +4.00% | |
| 5.44 | 5.62 | 5.11 | 5.25 | -3.31% | |
| 5.53 | 5.82 | 5.30 | 5.43 | -1.09% | |
| 5.55 | 5.61 | 5.25 | 5.49 | -1.96% | |
| 5.39 | 5.63 | 5.24 | 5.60 | +2.38% | |
| 6.27 | 6.38 | 5.42 | 5.47 | -13.72% | |
| 6.48 | 6.61 | 6.21 | 6.34 | -3.35% | |
| 6.61 | 6.71 | 6.37 | 6.56 | -0.46% | |
| 6.57 | 6.70 | 6.31 | 6.59 | +1.85% | |
| 6.64 | 6.83 | 6.12 | 6.47 | -2.41% | |
| 6.56 | 6.82 | 6.40 | 6.63 | +2.00% | |
| 5.70 | 6.65 | 5.70 | 6.50 | +12.46% | |
| 5.84 | 5.90 | 5.66 | 5.78 | +0.52% | |
| 5.62 | 5.78 | 5.49 | 5.75 | +2.13% | |
| 5.57 | 5.86 | 5.45 | 5.63 | +1.44% | |
| 5.45 | 5.61 | 5.15 | 5.55 | +3.54% | |
| 5.77 | 5.91 | 5.21 | 5.36 | -6.46% | |
| 5.39 | 5.90 | 5.39 | 5.73 | +7.71% | |
| 4.95 | 5.85 | 4.83 | 5.32 | +10.14% | |
| 4.91 | 5.00 | 4.81 | 4.83 | -1.43% | |
| 4.74 | 4.92 | 4.63 | 4.90 | +4.70% | |
| 4.47 | 4.75 | 4.47 | 4.68 | +3.08% | |
| 4.51 | 4.60 | 4.37 | 4.54 | +0.44% | |
| 4.41 | 4.58 | 4.41 | 4.52 | +2.96% | |
| 4.65 | 4.65 | 4.35 | 4.39 | -4.57% | |
| 5.03 | 5.15 | 4.57 | 4.60 | -8.91% | |
| 4.71 | 5.13 | 4.71 | 5.05 | +7.22% | |
| 4.64 | 4.98 | 4.32 | 4.71 | +1.51% | |
| 4.55 | 4.87 | 4.19 | 4.64 | +19.28% | |
| 3.86 | 4.05 | 3.86 | 3.89 | +1.57% | |
| 3.95 | 3.95 | 3.77 | 3.83 | -2.54% | |
| 3.84 | 3.96 | 3.77 | 3.93 | +0.13% | |
| 4.02 | 4.07 | 3.90 | 3.93 | -2.85% | |
| 4.03 | 4.21 | 4.01 | 4.04 | -0.49% | |
| 4.24 | 4.32 | 3.95 | 4.06 | -3.33% | |
| 4.08 | 4.31 | 4.01 | 4.20 | +0.48% | |
| 4.43 | 4.43 | 4.03 | 4.18 | -6.28% | |
| 4.38 | 4.56 | 4.31 | 4.46 | +1.59% | |
| 4.48 | 4.55 | 4.35 | 4.39 | -1.13% | |
| 4.73 | 4.73 | 4.41 | 4.44 | -7.60% | |
| 4.92 | 4.98 | 4.35 | 4.81 | -2.14% | |
| 5.14 | 5.33 | 4.84 | 4.91 | -4.10% | |
| 4.96 | 5.28 | 4.88 | 5.12 | +3.02% | |
| 4.96 | 5.06 | 4.65 | 4.97 | -0.40% | |
| 4.92 | 5.13 | 4.84 | 4.99 | +1.63% | |
| 4.83 | 5.21 | 4.82 | 4.91 | 0.00% | |
| 5.32 | 5.44 | 4.77 | 4.91 | -7.88% | |
| 4.90 | 5.69 | 4.90 | 5.33 | +8.11% | |
| 4.28 | 4.99 | 4.28 | 4.93 | +12.56% | |
| 4.08 | 4.38 | 4.02 | 4.38 | +6.83% | |
| 4.40 | 4.40 | 4.02 | 4.10 | -3.98% | |
| 4.36 | 4.50 | 4.26 | 4.27 | -2.51% | |
| 4.25 | 4.43 | 4.12 | 4.38 | +1.39% | |
| 4.14 | 4.45 | 4.14 | 4.32 | 0.00% | |
| 4.38 | 4.64 | 4.16 | 4.32 | -0.69% | |
| 4.20 | 4.43 | 4.07 | 4.35 | +3.57% | |
| 4.48 | 4.48 | 4.10 | 4.20 | -5.83% | |
| 4.60 | 4.69 | 4.42 | 4.46 | -0.67% | |
| 4.03 | 4.52 | 3.97 | 4.49 | +9.25% | |
| 3.95 | 4.13 | 3.89 | 4.11 | +4.05% | |
| 3.93 | 4.11 | 3.89 | 3.95 | +0.25% | |
| 3.87 | 4.04 | 3.76 | 3.94 | +2.60% | |
| 3.86 | 4.00 | 3.76 | 3.84 | +0.79% | |
| 4.05 | 4.06 | 3.74 | 3.81 | -6.62% | |
| 3.66 | 4.19 | 3.61 | 4.08 | +11.48% | |
| 3.49 | 3.72 | 3.40 | 3.66 | +4.57% | |
| 3.76 | 3.76 | 3.47 | 3.50 | -8.38% | |
| 3.90 | 4.00 | 3.81 | 3.82 | -2.55% | |
| 3.93 | 4.00 | 3.76 | 3.92 | -0.25% | |
| 4.13 | 4.13 | 3.80 | 3.93 | -5.53% | |
| 4.14 | 4.38 | 4.10 | 4.16 | +1.71% | |
| 4.14 | 4.31 | 4.03 | 4.09 | -4.22% | |
| 4.37 | 4.52 | 4.16 | 4.27 | -1.39% | |
| 4.40 | 4.53 | 4.31 | 4.33 | -3.78% | |
| 4.30 | 4.54 | 4.12 | 4.50 | +5.39% | |
| 4.27 | 4.47 | 3.95 | 4.27 | -1.61% | |
| 4.44 | 4.75 | 4.26 | 4.34 | -3.13% | |
| 4.33 | 4.60 | 4.10 | 4.48 | +0.22% | |
| 4.62 | 4.67 | 4.40 | 4.47 | -4.08% | |
| 4.57 | 4.81 | 4.42 | 4.66 | +0.43% | |
| 4.80 | 4.98 | 4.55 | 4.64 | -3.33% | |
| 4.85 | 5.14 | 4.75 | 4.80 | -1.23% | |
| 5.15 | 5.32 | 4.79 | 4.86 | -5.63% | |
| 4.88 | 5.31 | 4.65 | 5.15 | +6.40% | |
| 4.78 | 5.05 | 4.32 | 4.84 | +3.64% | |
| 4.82 | 5.13 | 4.65 | 4.67 | -1.48% | |
| 4.82 | 4.92 | 4.50 | 4.74 | +0.85% | |
| 5.18 | 5.26 | 4.50 | 4.70 | -10.13% | |
| 4.52 | 5.23 | 4.27 | 5.23 | +22.48% | |
| 4.31 | 4.37 | 4.04 | 4.27 | -2.73% | |
| 4.53 | 4.76 | 4.17 | 4.39 | -2.88% | |
| 4.92 | 5.08 | 4.43 | 4.52 | -3.83% | |
| 4.88 | 4.88 | 4.44 | 4.70 | +6.82% | |
| 4.33 | 4.43 | 3.89 | 4.40 | +2.09% | |
| 4.66 | 4.73 | 4.28 | 4.31 | -6.71% | |
| 4.69 | 4.99 | 4.48 | 4.62 | +2.44% | |
| 5.09 | 5.50 | 4.50 | 4.51 | +1.58% | |
| 4.50 | 4.51 | 4.10 | 4.44 | +0.23% | |
| 5.50 | 5.51 | 4.21 | 4.43 | -19.75% | |
| 4.34 | 5.54 | 4.26 | 5.52 | +25.45% | |
| 4.48 | 4.48 | 4.27 | 4.40 | +0.69% | |
| 4.11 | 4.48 | 4.01 | 4.37 | +7.11% | |
| 4.43 | 4.62 | 4.08 | 4.08 | -7.27% | |
| 4.46 | 4.46 | 3.83 | 4.40 | +4.27% | |
| 4.50 | 4.82 | 4.19 | 4.22 | -4.09% | |
| 3.68 | 4.50 | 3.68 | 4.40 | +19.57% | |
| 3.51 | 3.90 | 3.48 | 3.68 | +6.36% | |
| 3.30 | 3.66 | 3.27 | 3.46 | +0.29% | |
| 3.45 | 3.69 | 3.44 | 3.45 | +0.88% | |
| 3.14 | 3.59 | 3.14 | 3.42 | +11.40% | |
| 3.10 | 3.21 | 3.01 | 3.07 | +0.66% | |
| 3.23 | 3.32 | 3.01 | 3.05 | -5.86% | |
| 3.20 | 3.31 | 3.12 | 3.24 | -0.61% | |
| 3.15 | 3.40 | 3.15 | 3.26 | +4.49% | |
| 3.06 | 3.30 | 3.06 | 3.12 | -1.27% | |
| 3.06 | 3.23 | 2.92 | 3.16 | +5.69% | |
| 3.12 | 3.24 | 2.83 | 2.99 | -6.27% | |
| 3.09 | 3.44 | 3.08 | 3.19 | +2.24% | |
| 3.43 | 3.43 | 3.04 | 3.12 | -9.04% | |
| 3.40 | 3.60 | 3.37 | 3.43 | +2.08% | |
| 3.35 | 3.70 | 3.24 | 3.36 | +1.82% | |
| 3.35 | 3.45 | 3.10 | 3.30 | -2.08% | |
| 3.71 | 3.81 | 3.33 | 3.37 | -11.55% | |
| 3.73 | 4.00 | 3.51 | 3.81 | +5.83% | |
| 2.99 | 3.64 | 2.99 | 3.60 | +16.50% | |
| 3.19 | 3.47 | 3.06 | 3.09 | -4.33% | |
| 3.05 | 3.38 | 3.05 | 3.23 | +3.53% | |
| 2.82 | 3.12 | 2.76 | 3.12 | +11.03% | |
| 2.70 | 2.91 | 2.60 | 2.81 | +6.84% | |
| 2.62 | 2.75 | 2.54 | 2.63 | -2.95% | |
| 2.68 | 2.83 | 2.66 | 2.71 | -1.81% | |
| 2.81 | 2.84 | 2.67 | 2.76 | -3.83% | |
| 3.23 | 3.27 | 2.78 | 2.87 | -12.77% | |
| 2.90 | 3.32 | 2.85 | 3.29 | +15.03% | |
| 2.76 | 3.31 | 2.68 | 2.86 | +3.25% | |
| 2.79 | 3.04 | 2.60 | 2.77 | -0.36% | |
| 2.26 | 2.80 | 2.19 | 2.78 | +22.47% | |
| 2.16 | 2.33 | 2.06 | 2.27 | +5.58% | |
| 2.11 | 2.19 | 2.09 | 2.15 | +1.90% | |
| 2.22 | 2.23 | 2.07 | 2.11 | -5.38% | |
| 2.27 | 2.37 | 2.18 | 2.23 | -0.45% | |
| 2.10 | 2.30 | 2.01 | 2.24 | +7.18% | |
| 2.14 | 2.16 | 1.95 | 2.09 | -0.48% | |
| 2.15 | 2.15 | 2.00 | 2.10 | -2.55% | |
| 2.15 | 2.17 | 2.04 | 2.16 | -0.69% | |
| 2.07 | 2.21 | 1.98 | 2.17 | +7.43% | |
| 2.26 | 2.26 | 1.97 | 2.02 | -12.17% | |
| 2.30 | 2.35 | 2.16 | 2.30 | +0.44% | |
| 2.09 | 2.35 | 2.05 | 2.29 | +12.81% | |
| 1.85 | 2.07 | 1.85 | 2.03 | +9.73% | |
| 1.87 | 1.93 | 1.80 | 1.85 | -2.63% | |
| 1.99 | 2.05 | 1.80 | 1.90 | -3.55% | |
| 2.15 | 2.15 | 1.97 | 1.97 | -7.08% | |
| 2.02 | 2.20 | 1.99 | 2.12 | +4.43% | |
| 2.01 | 2.10 | 1.90 | 2.03 | +0.50% | |
| 2.20 | 2.21 | 1.99 | 2.02 | -8.60% | |
| 1.81 | 2.30 | 1.81 | 2.21 | +21.43% | |
| 1.84 | 1.95 | 1.82 | 1.82 | -1.09% | |
| 1.83 | 1.96 | 1.77 | 1.84 | +1.66% | |
| 2.10 | 2.10 | 1.78 | 1.81 | -15.81% | |
| 2.27 | 2.27 | 2.09 | 2.15 | -4.87% | |
| 2.18 | 2.30 | 2.13 | 2.26 | +0.89% | |
| 2.17 | 2.26 | 2.05 | 2.24 | +1.82% | |
| 2.61 | 2.67 | 2.10 | 2.20 | -16.35% | |
| 2.78 | 2.82 | 2.63 | 2.63 | -4.71% | |
| 2.80 | 2.99 | 2.74 | 2.76 | -2.47% | |
| 2.64 | 2.87 | 2.56 | 2.83 | +10.55% | |
| 2.48 | 2.64 | 2.41 | 2.56 | +4.92% | |
| 2.71 | 2.79 | 2.37 | 2.44 | -10.62% | |
| 2.90 | 2.90 | 2.60 | 2.73 | -5.86% | |
| 2.81 | 2.95 | 2.75 | 2.90 | +2.11% | |
| 2.95 | 2.98 | 2.64 | 2.84 | -3.40% | |
| 2.42 | 3.00 | 2.36 | 2.94 | +20.00% | |
| 2.26 | 2.48 | 2.21 | 2.45 | +9.87% | |
| 2.20 | 2.33 | 2.20 | 2.23 | +1.83% | |
| 2.23 | 2.25 | 2.12 | 2.19 | -3.10% | |
| 2.17 | 2.38 | 2.09 | 2.26 | +5.61% | |
| 1.94 | 2.15 | 1.90 | 2.14 | +11.46% | |
| 1.98 | 2.02 | 1.90 | 1.92 | -1.54% | |
| 2.03 | 2.17 | 1.87 | 1.95 | -2.01% | |
| 1.90 | 2.06 | 1.79 | 1.99 | +2.58% | |
| 1.72 | 1.98 | 1.71 | 1.94 | +13.45% | |
| 1.62 | 1.72 | 1.60 | 1.71 | +4.91% | |
| 1.65 | 1.69 | 1.61 | 1.63 | -1.21% | |
| 1.71 | 1.72 | 1.62 | 1.65 | -2.94% | |
| 1.47 | 1.70 | 1.46 | 1.70 | +16.44% | |
| 1.50 | 1.51 | 1.45 | 1.46 | 0.00% | |
| 1.56 | 1.56 | 1.43 | 1.46 | -5.19% | |
| 1.34 | 1.55 | 1.34 | 1.54 | +11.59% | |
| 1.33 | 1.40 | 1.30 | 1.38 | +2.60% | |
| 1.55 | 1.55 | 1.34 | 1.35 | -13.23% | |
| 1.67 | 1.67 | 1.51 | 1.55 | -7.74% | |
| 1.66 | 1.70 | 1.60 | 1.68 | +0.60% | |
| 1.59 | 1.68 | 1.53 | 1.67 | +5.03% | |
| 1.42 | 1.60 | 1.32 | 1.59 | +13.57% | |
| 1.66 | 1.66 | 1.40 | 1.40 | -16.17% | |
| 1.61 | 1.69 | 1.52 | 1.67 | +4.37% | |
| 1.65 | 1.68 | 1.50 | 1.60 | -4.19% | |
| 1.65 | 1.70 | 1.61 | 1.67 | -0.60% | |
| 1.63 | 1.73 | 1.55 | 1.68 | +1.82% | |
| 1.52 | 1.69 | 1.46 | 1.65 | +8.55% | |
| 1.47 | 1.54 | 1.42 | 1.52 | +0.66% | |
| 1.48 | 1.62 | 1.42 | 1.51 | +2.72% | |
| 1.38 | 1.48 | 1.34 | 1.47 | +8.89% | |
| 1.27 | 1.40 | 1.21 | 1.35 | +7.14% | |
| 1.19 | 1.29 | 1.17 | 1.26 | +5.88% | |
| 1.33 | 1.33 | 1.19 | 1.19 | -11.85% | |
| 1.38 | 1.51 | 1.34 | 1.35 | -2.88% | |
| 1.65 | 1.65 | 1.38 | 1.39 | -21.02% | |
| 2.12 | 2.20 | 1.53 | 1.76 | -55.78% | |
| 1.58 | 4.22 | 1.43 | 3.98 | +150.31% | |
| 1.56 | 1.64 | 1.51 | 1.59 | +1.27% | |
| 1.57 | 1.61 | 1.47 | 1.57 | -0.63% | |
| 1.57 | 1.62 | 1.50 | 1.58 | +2.60% | |
| 1.72 | 1.72 | 1.54 | 1.54 | -9.94% | |
| 1.66 | 1.72 | 1.57 | 1.71 | +5.56% | |
| 1.50 | 1.63 | 1.49 | 1.62 | +8.00% | |
| 1.59 | 1.59 | 1.47 | 1.50 | -5.06% | |
| 1.60 | 1.68 | 1.44 | 1.58 | -3.66% | |
| 1.29 | 1.65 | 1.23 | 1.64 | +27.13% | |
| 1.17 | 1.30 | 1.16 | 1.29 | +8.40% | |
| 1.30 | 1.35 | 1.16 | 1.19 | -9.16% | |
| 1.36 | 1.42 | 1.27 | 1.31 | -3.68% | |
| 1.31 | 1.40 | 1.29 | 1.36 | +4.62% | |
| 1.27 | 1.32 | 1.21 | 1.30 | +4.00% | |
| 1.25 | 1.29 | 1.20 | 1.25 | -0.79% | |
| 1.39 | 1.41 | 1.15 | 1.26 | -10.00% | |
| 1.45 | 1.46 | 1.32 | 1.40 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the PRLD chart for longer ranges.