Septerna Stock Price History
NASDAQ: SEPNHealth CareBiotechnology: Pharmaceutical PreparationsUSD
38.37+1.47 (+3.98%)
At close: Oct 9, 4:00 PM ET · Delayed 15 min
SEPN price history at a glance
The price history for Septerna (SEPN) on this page begins on October 21, 2024, when the stock closed at $21.40; it most recently closed at $38.37 on October 5, 2026. The highest price in this record is $51.10, reached on August 10, 2026; the latest close is 24.9% below that peak. In the last 12 months alone, SEPN has gained 66.3%.
Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2024
- $51.10
- Date of high
- Aug 10, 2026
- Low since 2024
- $4.17
- Date of low
- Feb 17, 2025
- 52-week high
- $51.10
- 52-week low
- $17.55
- IPO year
- 2024
- Last close
- $38.37
SEPN returns
1 week
+1.75%
1 month
+1.05%
3 months
+6.79%
6 months
+66.18%
Year to date
+37.63%
1 year
+66.32%
SEPN price return, excluding dividends.
SEPN annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 38.37 | +37.13% |
| 2025 | 27.98 | +18.11% |
| 2024* | 23.69 | +10.70% |
* Partial year: the record begins after the start of 2024; return measured from the first available close.
2026 return is year to date.
SEPN daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 36.76 | 38.66 | 35.77 | 38.37 | +3.98% | |
| 35.47 | 37.09 | 34.66 | 36.90 | +2.50% | |
| 35.26 | 37.14 | 35.21 | 36.00 | +0.93% | |
| 37.97 | 38.69 | 35.60 | 35.67 | -5.81% | |
| 37.83 | 38.52 | 36.82 | 37.87 | +0.42% | |
| 38.84 | 39.11 | 37.31 | 37.71 | -0.89% | |
| 38.90 | 39.52 | 37.81 | 38.05 | -2.76% | |
| 39.13 | 39.85 | 38.49 | 39.13 | 0.00% | |
| 39.52 | 39.57 | 38.37 | 39.13 | -1.53% | |
| 37.61 | 39.78 | 37.03 | 39.74 | +5.22% | |
| 38.34 | 38.34 | 37.35 | 37.77 | -0.94% | |
| 38.41 | 38.81 | 37.49 | 38.13 | -0.83% | |
| 40.17 | 40.17 | 36.98 | 38.45 | -4.78% | |
| 38.78 | 41.09 | 38.74 | 40.38 | +4.77% | |
| 38.97 | 39.47 | 38.01 | 38.54 | -0.39% | |
| 39.28 | 39.48 | 37.88 | 38.69 | -2.05% | |
| 39.38 | 40.52 | 39.01 | 39.50 | +2.76% | |
| 39.15 | 40.24 | 37.92 | 38.44 | -1.08% | |
| 39.52 | 39.52 | 38.26 | 38.86 | -1.74% | |
| 38.66 | 39.95 | 38.51 | 39.55 | +2.70% | |
| 37.75 | 40.02 | 37.56 | 38.51 | +2.01% | |
| 37.37 | 38.43 | 36.60 | 37.75 | -0.58% | |
| 37.15 | 39.40 | 37.15 | 37.97 | +1.61% | |
| 36.15 | 38.06 | 36.01 | 37.37 | +1.69% | |
| 36.57 | 37.59 | 36.57 | 36.75 | -0.14% | |
| 37.72 | 38.20 | 36.46 | 36.80 | -1.87% | |
| 37.96 | 38.86 | 37.25 | 37.50 | -0.48% | |
| 38.15 | 38.57 | 37.24 | 37.68 | -1.23% | |
| 38.71 | 39.11 | 37.39 | 38.15 | -1.95% | |
| 40.25 | 40.95 | 38.74 | 38.91 | -3.85% | |
| 40.01 | 41.08 | 39.95 | 40.47 | +0.55% | |
| 41.08 | 41.36 | 40.12 | 40.25 | -2.54% | |
| 41.57 | 41.85 | 40.47 | 41.30 | +1.92% | |
| 39.76 | 40.90 | 38.96 | 40.52 | +1.30% | |
| 41.44 | 41.44 | 39.95 | 40.00 | -1.94% | |
| 43.15 | 43.62 | 40.24 | 40.79 | -7.15% | |
| 44.65 | 44.93 | 43.49 | 43.93 | +0.30% | |
| 43.69 | 44.58 | 43.37 | 43.80 | -0.90% | |
| 44.01 | 45.41 | 43.69 | 44.20 | -0.67% | |
| 45.00 | 46.50 | 43.64 | 44.50 | -1.42% | |
| 47.83 | 48.95 | 45.10 | 45.14 | -6.33% | |
| 47.93 | 51.10 | 47.40 | 48.19 | +0.90% | |
| 39.57 | 48.00 | 38.62 | 47.76 | +22.93% | |
| 38.56 | 39.71 | 38.05 | 38.85 | +0.05% | |
| 39.98 | 40.65 | 38.11 | 38.83 | -1.77% | |
| 39.00 | 40.12 | 38.78 | 39.53 | +1.99% | |
| 38.92 | 40.63 | 38.46 | 38.76 | -0.56% | |
| 35.55 | 39.12 | 35.55 | 38.98 | +11.44% | |
| 34.45 | 35.25 | 33.19 | 34.98 | +1.54% | |
| 34.97 | 35.49 | 33.49 | 34.45 | -2.08% | |
| 34.00 | 35.82 | 34.00 | 35.18 | +4.67% | |
| 33.97 | 34.58 | 33.25 | 33.61 | -1.06% | |
| 33.77 | 35.11 | 32.85 | 33.97 | +1.43% | |
| 33.25 | 34.40 | 33.03 | 33.49 | +1.18% | |
| 33.88 | 34.97 | 32.48 | 33.10 | -1.11% | |
| 33.32 | 34.50 | 32.96 | 33.47 | -2.13% | |
| 33.32 | 34.51 | 32.74 | 34.20 | +1.54% | |
| 32.20 | 35.11 | 31.85 | 33.68 | +4.56% | |
| 33.35 | 34.28 | 32.17 | 32.21 | -3.56% | |
| 30.98 | 34.29 | 30.55 | 33.40 | +5.83% | |
| 33.99 | 34.32 | 31.44 | 31.56 | -7.37% | |
| 34.50 | 35.26 | 32.33 | 34.07 | -1.36% | |
| 34.27 | 35.37 | 33.54 | 34.54 | +0.52% | |
| 35.64 | 36.01 | 33.91 | 34.36 | -4.37% | |
| 37.97 | 37.97 | 35.43 | 35.93 | -5.05% | |
| 36.43 | 38.04 | 36.07 | 37.84 | +3.96% | |
| 35.37 | 37.26 | 34.75 | 36.40 | +1.59% | |
| 34.46 | 37.75 | 34.43 | 35.83 | +7.05% | |
| 33.38 | 34.30 | 32.91 | 33.47 | -1.56% | |
| 34.68 | 34.85 | 33.25 | 34.00 | -1.76% | |
| 33.45 | 35.17 | 33.02 | 34.61 | +3.34% | |
| 34.69 | 34.78 | 32.65 | 33.49 | -3.63% | |
| 35.18 | 35.99 | 32.00 | 34.75 | -6.94% | |
| 34.44 | 37.48 | 34.23 | 37.34 | +8.11% | |
| 36.36 | 36.40 | 34.35 | 34.54 | -4.19% | |
| 36.90 | 37.99 | 35.61 | 36.05 | -1.42% | |
| 34.67 | 37.50 | 34.28 | 36.57 | +4.94% | |
| 36.46 | 37.24 | 34.68 | 34.85 | -3.65% | |
| 36.24 | 37.32 | 34.51 | 36.17 | +1.03% | |
| 35.17 | 36.12 | 33.88 | 35.80 | +1.79% | |
| 35.93 | 36.62 | 35.06 | 35.17 | -2.39% | |
| 36.27 | 37.01 | 35.37 | 36.03 | +0.22% | |
| 34.03 | 36.26 | 33.85 | 35.95 | +5.64% | |
| 30.86 | 34.19 | 30.74 | 34.03 | +11.68% | |
| 31.00 | 31.98 | 30.41 | 30.47 | -1.74% | |
| 30.69 | 31.90 | 30.24 | 31.01 | +1.97% | |
| 31.97 | 32.38 | 30.05 | 30.41 | -2.38% | |
| 30.99 | 31.41 | 30.47 | 31.15 | -0.70% | |
| 30.61 | 31.79 | 30.61 | 31.37 | +2.68% | |
| 29.89 | 30.84 | 29.57 | 30.55 | +2.04% | |
| 29.56 | 30.28 | 29.12 | 29.94 | -0.13% | |
| 29.59 | 30.36 | 27.08 | 29.98 | -0.73% | |
| 30.96 | 31.60 | 29.71 | 30.20 | -2.74% | |
| 29.71 | 31.40 | 29.22 | 31.05 | +4.23% | |
| 30.61 | 30.95 | 29.32 | 29.79 | -2.79% | |
| 28.49 | 30.78 | 27.66 | 30.65 | +8.06% | |
| 27.93 | 29.89 | 27.93 | 28.36 | +1.58% | |
| 27.62 | 28.60 | 27.49 | 27.92 | -0.32% | |
| 26.77 | 28.06 | 26.71 | 28.01 | +5.66% | |
| 26.21 | 27.16 | 25.79 | 26.51 | +0.80% | |
| 27.08 | 27.98 | 26.00 | 26.30 | -2.41% | |
| 27.62 | 28.81 | 26.28 | 26.95 | -4.84% | |
| 24.84 | 28.37 | 24.03 | 28.32 | +14.42% | |
| 24.50 | 25.48 | 24.23 | 24.75 | -0.36% | |
| 24.46 | 25.99 | 23.57 | 24.84 | +5.39% | |
| 23.87 | 24.65 | 23.50 | 23.57 | -1.26% | |
| 23.98 | 24.86 | 23.82 | 23.87 | -0.46% | |
| 24.77 | 25.05 | 23.44 | 23.98 | -2.95% | |
| 24.25 | 24.90 | 23.90 | 24.71 | +2.40% | |
| 25.00 | 25.25 | 23.29 | 24.13 | -2.78% | |
| 23.52 | 25.20 | 23.52 | 24.82 | +5.12% | |
| 23.84 | 24.59 | 23.15 | 23.61 | -0.63% | |
| 23.45 | 24.24 | 23.12 | 23.76 | +1.32% | |
| 24.00 | 24.57 | 22.78 | 23.45 | -3.46% | |
| 25.09 | 25.51 | 23.95 | 24.29 | -3.19% | |
| 24.60 | 25.86 | 24.58 | 25.09 | +1.70% | |
| 24.86 | 25.40 | 24.49 | 24.67 | -1.20% | |
| 25.82 | 27.17 | 24.94 | 24.97 | -3.44% | |
| 25.95 | 26.20 | 25.34 | 25.86 | +0.23% | |
| 27.00 | 27.30 | 25.53 | 25.80 | -3.95% | |
| 25.95 | 27.08 | 25.59 | 26.86 | +2.79% | |
| 25.50 | 26.57 | 24.84 | 26.13 | +4.56% | |
| 25.92 | 26.85 | 24.98 | 24.99 | -3.63% | |
| 24.13 | 25.99 | 23.31 | 25.93 | +7.46% | |
| 23.57 | 24.40 | 23.35 | 24.13 | +3.38% | |
| 23.00 | 24.33 | 22.83 | 23.34 | +1.08% | |
| 24.92 | 24.92 | 22.97 | 23.09 | -7.01% | |
| 24.40 | 25.22 | 24.18 | 24.83 | +1.39% | |
| 25.71 | 25.83 | 24.22 | 24.49 | -1.41% | |
| 24.67 | 24.89 | 24.05 | 24.84 | +0.24% | |
| 24.88 | 25.48 | 24.38 | 24.78 | -1.59% | |
| 23.90 | 25.29 | 23.90 | 25.18 | +3.32% | |
| 24.33 | 24.94 | 24.18 | 24.37 | +1.41% | |
| 23.74 | 24.86 | 23.50 | 24.03 | +3.13% | |
| 23.95 | 24.17 | 22.89 | 23.30 | -2.39% | |
| 24.68 | 25.16 | 23.75 | 23.87 | -3.52% | |
| 23.98 | 25.00 | 23.40 | 24.74 | +2.19% | |
| 23.69 | 25.08 | 23.50 | 24.21 | +3.28% | |
| 23.77 | 23.92 | 22.97 | 23.44 | -1.43% | |
| 24.63 | 25.33 | 23.57 | 23.78 | -1.65% | |
| 24.26 | 24.51 | 23.82 | 24.18 | -0.41% | |
| 23.83 | 24.57 | 23.35 | 24.28 | +0.71% | |
| 25.10 | 25.35 | 24.04 | 24.11 | -4.21% | |
| 25.15 | 25.72 | 24.14 | 25.17 | +0.12% | |
| 25.43 | 27.00 | 24.75 | 25.14 | 0.00% | |
| 26.49 | 27.02 | 24.96 | 25.14 | -4.93% | |
| 25.86 | 26.73 | 25.25 | 26.45 | +0.51% | |
| 27.45 | 28.00 | 26.29 | 26.31 | -6.10% | |
| 29.40 | 29.82 | 27.22 | 28.02 | -3.58% | |
| 28.79 | 30.00 | 28.25 | 29.06 | +0.97% | |
| 27.05 | 28.89 | 26.62 | 28.78 | +4.77% | |
| 28.26 | 28.26 | 25.98 | 27.47 | -4.70% | |
| 28.60 | 29.03 | 27.50 | 28.83 | +2.47% | |
| 28.51 | 28.64 | 27.16 | 28.13 | -1.78% | |
| 28.11 | 29.50 | 26.58 | 28.64 | -1.31% | |
| 29.79 | 30.33 | 28.44 | 29.02 | -4.16% | |
| 30.00 | 30.70 | 29.29 | 30.28 | +0.97% | |
| 31.09 | 32.63 | 29.79 | 29.99 | -2.82% | |
| 28.22 | 30.92 | 28.07 | 30.86 | +10.21% | |
| 27.30 | 28.17 | 26.84 | 28.00 | +2.64% | |
| 26.85 | 27.40 | 25.49 | 27.28 | +0.74% | |
| 28.17 | 28.17 | 26.26 | 27.08 | -4.31% | |
| 30.08 | 30.52 | 27.96 | 28.30 | -6.60% | |
| 27.60 | 31.37 | 27.60 | 30.30 | +10.18% | |
| 25.70 | 27.64 | 25.12 | 27.50 | +6.75% | |
| 26.70 | 26.70 | 25.22 | 25.76 | -2.20% | |
| 26.97 | 26.97 | 25.36 | 26.34 | -1.35% | |
| 26.54 | 27.31 | 26.10 | 26.70 | +0.41% | |
| 25.47 | 26.96 | 24.98 | 26.59 | +4.64% | |
| 24.73 | 25.76 | 24.13 | 25.41 | +3.97% | |
| 24.48 | 25.54 | 24.00 | 24.44 | -1.97% | |
| 25.76 | 25.92 | 24.75 | 24.93 | -2.39% | |
| 24.95 | 25.71 | 24.95 | 25.54 | +2.04% | |
| 23.34 | 25.81 | 23.02 | 25.03 | +7.24% | |
| 23.40 | 23.94 | 23.23 | 23.34 | -1.93% | |
| 23.96 | 24.81 | 23.67 | 23.80 | +0.59% | |
| 25.36 | 25.63 | 23.45 | 23.66 | -7.03% | |
| 25.98 | 26.52 | 25.20 | 25.45 | -2.00% | |
| 25.72 | 26.60 | 25.35 | 25.97 | +0.80% | |
| 26.64 | 26.82 | 25.35 | 25.77 | -3.39% | |
| 26.41 | 27.53 | 26.31 | 26.67 | +1.21% | |
| 26.97 | 27.40 | 26.01 | 26.35 | -2.52% | |
| 26.37 | 27.95 | 26.17 | 27.03 | +3.68% | |
| 27.39 | 28.15 | 25.99 | 26.07 | -4.78% | |
| 26.86 | 27.83 | 26.27 | 27.38 | +2.43% | |
| 26.24 | 27.76 | 25.92 | 26.73 | +1.33% | |
| 24.84 | 26.73 | 24.44 | 26.38 | +6.03% | |
| 25.49 | 25.54 | 24.66 | 24.88 | -1.66% | |
| 25.74 | 26.71 | 25.25 | 25.30 | -1.71% | |
| 26.11 | 26.28 | 25.38 | 25.74 | -2.54% | |
| 25.60 | 26.75 | 25.50 | 26.41 | +3.77% | |
| 26.79 | 27.09 | 25.24 | 25.45 | -5.00% | |
| 28.47 | 28.47 | 26.20 | 26.79 | -4.25% | |
| 28.20 | 29.00 | 27.72 | 27.98 | +0.36% | |
| 27.62 | 28.32 | 27.50 | 27.88 | +0.36% | |
| 28.44 | 28.50 | 27.51 | 27.78 | -2.11% | |
| 28.31 | 29.23 | 28.31 | 28.38 | -0.84% | |
| 29.00 | 29.06 | 28.10 | 28.62 | -2.88% | |
| 28.34 | 29.66 | 28.26 | 29.47 | +4.39% | |
| 29.00 | 29.50 | 27.93 | 28.23 | -4.21% | |
| 29.65 | 29.88 | 28.61 | 29.47 | -0.37% | |
| 28.54 | 30.50 | 28.50 | 29.58 | +7.41% | |
| 26.95 | 28.12 | 26.32 | 27.54 | +3.73% | |
| 26.33 | 26.76 | 25.40 | 26.55 | +1.22% | |
| 26.94 | 28.43 | 26.19 | 26.23 | -3.50% | |
| 25.70 | 27.78 | 25.70 | 27.18 | +6.84% | |
| 26.47 | 26.49 | 25.35 | 25.44 | -2.94% | |
| 25.60 | 26.70 | 24.77 | 26.21 | +2.22% | |
| 25.56 | 26.01 | 24.63 | 25.64 | +0.59% | |
| 25.96 | 26.40 | 25.24 | 25.49 | -1.81% | |
| 27.14 | 27.49 | 25.83 | 25.96 | -2.99% | |
| 26.43 | 26.87 | 25.71 | 26.76 | +2.29% | |
| 26.40 | 26.80 | 25.74 | 26.16 | -1.47% | |
| 26.12 | 26.65 | 25.46 | 26.55 | +1.45% | |
| 27.71 | 27.98 | 26.12 | 26.17 | -5.25% | |
| 28.81 | 29.14 | 27.55 | 27.62 | -4.82% | |
| 29.63 | 29.69 | 28.07 | 29.02 | -1.86% | |
| 28.00 | 29.74 | 26.55 | 29.57 | +5.72% | |
| 28.70 | 28.70 | 26.81 | 27.97 | -1.89% | |
| 26.28 | 29.43 | 26.28 | 28.51 | +11.54% | |
| 23.64 | 26.26 | 23.55 | 25.56 | +7.53% | |
| 23.36 | 24.44 | 23.31 | 23.77 | +2.90% | |
| 21.77 | 23.80 | 21.63 | 23.10 | +6.50% | |
| 21.73 | 22.43 | 21.31 | 21.69 | +0.23% | |
| 22.68 | 23.15 | 21.57 | 21.64 | -6.98% | |
| 19.69 | 23.99 | 19.69 | 23.27 | +20.92% | |
| 19.23 | 19.35 | 18.64 | 19.24 | +0.05% | |
| 19.32 | 19.82 | 18.85 | 19.23 | -0.05% | |
| 18.34 | 19.74 | 18.19 | 19.24 | +6.30% | |
| 18.79 | 20.05 | 17.98 | 18.10 | -2.22% | |
| 18.47 | 18.56 | 17.55 | 18.51 | -1.54% | |
| 18.96 | 19.50 | 18.65 | 18.80 | -1.73% | |
| 19.41 | 19.49 | 18.88 | 19.13 | -1.70% | |
| 19.48 | 19.70 | 19.10 | 19.46 | -2.94% | |
| 20.42 | 20.71 | 19.60 | 20.05 | -2.67% | |
| 21.49 | 21.49 | 20.03 | 20.60 | -4.14% | |
| 21.40 | 22.41 | 21.20 | 21.49 | -2.05% | |
| 22.34 | 22.36 | 21.40 | 21.94 | -1.70% | |
| 22.62 | 22.66 | 21.68 | 22.32 | -1.33% | |
| 22.01 | 23.45 | 21.62 | 22.62 | +4.38% | |
| 22.12 | 22.30 | 21.51 | 21.67 | -0.55% | |
| 22.09 | 22.45 | 21.10 | 21.79 | -0.95% | |
| 21.27 | 22.20 | 20.82 | 22.00 | +3.24% | |
| 22.52 | 22.52 | 20.93 | 21.31 | -5.04% | |
| 22.36 | 22.94 | 21.89 | 22.44 | +1.72% | |
| 22.52 | 22.56 | 21.31 | 22.06 | -2.24% | |
| 23.65 | 24.00 | 22.37 | 22.57 | -3.28% | |
| 23.59 | 23.81 | 22.65 | 23.33 | +0.13% | |
| 23.97 | 24.18 | 22.66 | 23.30 | -3.28% | |
| 23.07 | 24.92 | 22.64 | 24.09 | +4.42% | |
| 21.93 | 23.29 | 20.72 | 23.07 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the SEPN chart for longer ranges.