Taysha Gene Therapies Stock Price History
NASDAQ: TSHAHealth CareBiotechnology: Biological Products (No Diagnostic Substances)USD
4.49+0.06 (+1.35%)
At close: Oct 9, 4:00 PM ET · Delayed 15 min
TSHA price history at a glance
The price history for Taysha Gene Therapies (TSHA) on this page begins on September 21, 2020, when the stock closed at $24.47; it most recently closed at $4.49 on October 5, 2026. The highest price in this record is $33.35, reached on January 18, 2021; the latest close is 86.5% below that peak. Across the 5 complete calendar years in the table, TSHA finished higher in 2 and lower in 3. Its best year was 2025 (+173.4%) and its worst was 2022 (-80.6%).
Over roughly 6 years the share price changed -81.7%, a -24.5% compound annual price return (excluding dividends). In the last 12 months alone, TSHA has lost 10.2%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2020
- $33.35
- Date of high
- Jan 18, 2021
- Low since 2020
- $0.50
- Date of low
- Jun 26, 2023
- 52-week high
- $7.30
- 52-week low
- $3.69
- IPO year
- 2020
- Last close
- $4.49
TSHA returns
1 week
-3.02%
1 month
-15.92%
3 months
-29.18%
6 months
0.00%
Year to date
-18.36%
1 year
-10.20%
3 years
+98.67%
5 years
-74.89%
TSHA price return, excluding dividends.
TSHA annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 4.49 | -14.48% |
| 2025 | 5.25 | +173.44% |
| 2024 | 1.92 | +8.47% |
| 2023 | 1.77 | -21.68% |
| 2022 | 2.26 | -80.60% |
| 2021 | 11.65 | -56.10% |
| 2020* | 26.54 | +8.46% |
* Partial year: the record begins after the start of 2020; return measured from the first available close.
2026 return is year to date.
TSHA daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 4.42 | 4.57 | 4.36 | 4.49 | +1.35% | |
| 4.37 | 4.46 | 4.33 | 4.43 | 0.00% | |
| 4.33 | 4.46 | 4.26 | 4.43 | +0.91% | |
| 4.51 | 4.57 | 4.26 | 4.39 | -2.23% | |
| 4.64 | 4.64 | 4.37 | 4.49 | -3.02% | |
| 4.80 | 4.86 | 4.63 | 4.63 | -2.32% | |
| 4.86 | 4.94 | 4.73 | 4.74 | -2.67% | |
| 5.03 | 5.03 | 4.82 | 4.87 | -2.40% | |
| 4.97 | 5.03 | 4.80 | 4.99 | 0.00% | |
| 4.64 | 5.06 | 4.56 | 4.99 | +6.85% | |
| 4.88 | 4.88 | 4.67 | 4.67 | -2.51% | |
| 4.88 | 4.90 | 4.66 | 4.79 | -2.44% | |
| 5.11 | 5.14 | 4.88 | 4.91 | -4.84% | |
| 5.11 | 5.22 | 5.08 | 5.16 | +2.38% | |
| 5.07 | 5.12 | 5.00 | 5.04 | +0.40% | |
| 5.16 | 5.28 | 4.96 | 5.02 | -2.71% | |
| 5.25 | 5.46 | 5.05 | 5.16 | +1.78% | |
| 5.08 | 5.14 | 4.98 | 5.07 | +0.20% | |
| 5.00 | 5.19 | 4.90 | 5.06 | +1.00% | |
| 5.00 | 5.12 | 4.98 | 5.01 | -0.20% | |
| 5.26 | 5.28 | 4.98 | 5.02 | -2.71% | |
| 5.24 | 5.24 | 5.01 | 5.16 | -3.37% | |
| 5.40 | 5.49 | 5.29 | 5.34 | -2.55% | |
| 5.57 | 5.58 | 5.40 | 5.48 | -2.14% | |
| 5.52 | 5.61 | 5.42 | 5.60 | +0.54% | |
| 5.62 | 5.67 | 5.50 | 5.57 | -1.24% | |
| 5.73 | 5.96 | 5.55 | 5.64 | -1.05% | |
| 5.65 | 5.77 | 5.56 | 5.70 | +0.18% | |
| 5.70 | 5.78 | 5.54 | 5.69 | -1.39% | |
| 5.89 | 5.92 | 5.63 | 5.77 | -3.19% | |
| 5.99 | 6.09 | 5.89 | 5.96 | -1.00% | |
| 6.15 | 6.27 | 5.91 | 6.02 | -2.90% | |
| 5.99 | 6.27 | 5.99 | 6.20 | +3.85% | |
| 6.02 | 6.08 | 5.83 | 5.97 | -1.97% | |
| 6.18 | 6.24 | 6.02 | 6.09 | -0.33% | |
| 6.04 | 6.30 | 5.92 | 6.11 | -4.98% | |
| 6.40 | 6.52 | 6.29 | 6.43 | +3.88% | |
| 6.08 | 6.28 | 6.03 | 6.19 | -0.32% | |
| 5.93 | 6.27 | 5.82 | 6.21 | +4.37% | |
| 5.90 | 6.01 | 5.72 | 5.95 | -0.67% | |
| 6.40 | 6.40 | 5.94 | 5.99 | -6.48% | |
| 6.13 | 6.45 | 6.01 | 6.41 | -4.12% | |
| 6.42 | 6.75 | 6.28 | 6.68 | +4.87% | |
| 6.48 | 6.60 | 6.22 | 6.37 | -2.90% | |
| 6.45 | 6.57 | 6.35 | 6.56 | +3.47% | |
| 6.39 | 6.55 | 6.28 | 6.34 | -1.86% | |
| 6.29 | 6.47 | 6.20 | 6.46 | +4.19% | |
| 5.88 | 6.23 | 5.78 | 6.20 | +7.27% | |
| 5.89 | 5.96 | 5.63 | 5.78 | -1.37% | |
| 5.88 | 5.92 | 5.73 | 5.86 | -0.26% | |
| 5.61 | 5.93 | 5.54 | 5.88 | +4.72% | |
| 5.41 | 5.79 | 5.33 | 5.61 | +2.75% | |
| 5.51 | 5.68 | 5.28 | 5.46 | -1.44% | |
| 5.67 | 5.98 | 5.54 | 5.54 | +0.36% | |
| 5.89 | 5.95 | 5.46 | 5.52 | -5.32% | |
| 5.51 | 5.88 | 5.47 | 5.83 | +3.00% | |
| 5.61 | 5.72 | 5.55 | 5.66 | -0.18% | |
| 5.62 | 5.78 | 5.59 | 5.67 | +1.61% | |
| 5.95 | 6.05 | 5.57 | 5.58 | -6.38% | |
| 5.78 | 6.12 | 5.72 | 5.96 | -0.17% | |
| 6.15 | 6.27 | 5.88 | 5.97 | -3.55% | |
| 5.70 | 6.23 | 5.50 | 6.19 | +8.60% | |
| 5.39 | 5.86 | 5.31 | 5.70 | +5.95% | |
| 6.29 | 6.29 | 5.32 | 5.38 | -15.14% | |
| 6.52 | 6.54 | 5.99 | 6.34 | -3.50% | |
| 6.50 | 6.61 | 6.37 | 6.57 | +1.23% | |
| 6.46 | 6.59 | 6.26 | 6.49 | -0.15% | |
| 6.41 | 6.75 | 6.34 | 6.50 | +1.88% | |
| 6.45 | 6.57 | 6.25 | 6.38 | -2.30% | |
| 6.70 | 6.81 | 6.40 | 6.53 | -1.80% | |
| 6.76 | 6.85 | 6.56 | 6.65 | -2.35% | |
| 6.79 | 7.12 | 6.68 | 6.81 | +1.19% | |
| 6.47 | 6.81 | 6.32 | 6.73 | +6.15% | |
| 6.11 | 6.46 | 6.10 | 6.34 | +2.09% | |
| 6.83 | 6.83 | 6.06 | 6.21 | -10.52% | |
| 6.86 | 7.06 | 6.83 | 6.94 | +1.17% | |
| 6.47 | 7.06 | 6.46 | 6.86 | +5.05% | |
| 6.50 | 6.70 | 6.47 | 6.53 | +1.71% | |
| 6.25 | 6.57 | 6.24 | 6.42 | +3.72% | |
| 5.90 | 6.38 | 5.90 | 6.19 | +5.81% | |
| 5.98 | 6.04 | 5.62 | 5.85 | -2.01% | |
| 5.79 | 6.15 | 5.73 | 5.97 | +4.55% | |
| 5.58 | 6.06 | 5.55 | 5.71 | +2.33% | |
| 5.41 | 5.70 | 5.30 | 5.58 | +3.33% | |
| 5.35 | 5.60 | 5.29 | 5.40 | +0.75% | |
| 5.51 | 5.71 | 5.26 | 5.36 | -1.29% | |
| 5.60 | 5.68 | 5.34 | 5.43 | -1.27% | |
| 5.86 | 5.94 | 5.45 | 5.50 | -6.62% | |
| 5.61 | 5.94 | 5.55 | 5.89 | +6.13% | |
| 5.68 | 5.69 | 5.43 | 5.55 | -2.46% | |
| 5.85 | 5.93 | 5.62 | 5.69 | -4.69% | |
| 5.81 | 5.99 | 5.55 | 5.97 | +1.70% | |
| 5.93 | 5.95 | 5.73 | 5.87 | -0.84% | |
| 5.70 | 6.01 | 5.59 | 5.92 | +2.96% | |
| 5.68 | 5.94 | 5.55 | 5.75 | +2.86% | |
| 5.57 | 5.70 | 5.45 | 5.59 | +1.82% | |
| 5.54 | 5.67 | 5.42 | 5.49 | -0.90% | |
| 5.37 | 5.65 | 5.33 | 5.54 | +0.91% | |
| 5.25 | 5.54 | 5.17 | 5.49 | +5.88% | |
| 5.41 | 5.50 | 5.18 | 5.19 | -4.78% | |
| 5.91 | 6.04 | 5.36 | 5.45 | -8.64% | |
| 6.16 | 6.24 | 5.81 | 5.96 | -5.40% | |
| 6.65 | 6.75 | 6.27 | 6.30 | -5.55% | |
| 6.78 | 6.90 | 6.50 | 6.67 | -2.63% | |
| 6.83 | 6.91 | 6.66 | 6.85 | +0.44% | |
| 6.76 | 7.00 | 6.66 | 6.82 | +0.15% | |
| 6.60 | 7.01 | 6.58 | 6.81 | +2.10% | |
| 6.99 | 7.03 | 6.46 | 6.67 | -4.44% | |
| 6.61 | 7.30 | 6.50 | 6.98 | +0.58% | |
| 6.72 | 6.95 | 6.57 | 6.94 | +4.52% | |
| 6.33 | 6.65 | 6.28 | 6.64 | +4.90% | |
| 6.39 | 6.41 | 6.21 | 6.33 | -0.94% | |
| 6.32 | 6.55 | 6.21 | 6.39 | +1.91% | |
| 6.25 | 6.52 | 6.11 | 6.27 | -0.48% | |
| 6.57 | 6.72 | 6.18 | 6.30 | -2.48% | |
| 6.36 | 6.66 | 6.26 | 6.46 | +0.94% | |
| 6.42 | 6.47 | 6.24 | 6.40 | 0.00% | |
| 6.71 | 6.76 | 6.31 | 6.40 | -4.76% | |
| 6.36 | 6.73 | 6.13 | 6.72 | +8.04% | |
| 6.45 | 6.45 | 6.06 | 6.22 | -3.72% | |
| 6.48 | 6.70 | 6.28 | 6.46 | +0.47% | |
| 6.10 | 6.50 | 5.92 | 6.43 | +8.07% | |
| 5.86 | 6.02 | 5.75 | 5.95 | -0.83% | |
| 4.74 | 6.04 | 4.72 | 6.00 | +27.39% | |
| 4.42 | 4.71 | 4.42 | 4.71 | +6.56% | |
| 4.49 | 4.57 | 4.37 | 4.42 | -1.56% | |
| 4.62 | 4.65 | 4.34 | 4.49 | -3.02% | |
| 4.49 | 4.70 | 4.48 | 4.63 | +1.76% | |
| 4.75 | 4.78 | 4.44 | 4.55 | -0.44% | |
| 4.60 | 4.65 | 4.45 | 4.57 | -1.72% | |
| 4.47 | 4.74 | 4.47 | 4.65 | +6.41% | |
| 4.18 | 4.41 | 4.16 | 4.37 | +1.39% | |
| 4.51 | 4.61 | 4.30 | 4.31 | -3.58% | |
| 4.21 | 4.48 | 4.16 | 4.47 | +9.83% | |
| 4.10 | 4.15 | 4.03 | 4.07 | 0.00% | |
| 4.28 | 4.33 | 4.03 | 4.07 | -5.79% | |
| 4.46 | 4.60 | 4.30 | 4.32 | -5.68% | |
| 4.22 | 4.59 | 4.20 | 4.58 | +10.90% | |
| 4.47 | 4.52 | 4.08 | 4.13 | -9.03% | |
| 4.42 | 4.54 | 4.37 | 4.54 | +3.18% | |
| 4.58 | 4.62 | 4.34 | 4.40 | -3.51% | |
| 4.55 | 4.66 | 4.31 | 4.56 | +2.47% | |
| 4.53 | 4.60 | 4.43 | 4.45 | -2.63% | |
| 4.55 | 4.60 | 4.50 | 4.57 | +0.88% | |
| 4.56 | 4.64 | 4.48 | 4.53 | +0.89% | |
| 4.63 | 4.72 | 4.37 | 4.49 | -2.60% | |
| 4.41 | 4.63 | 4.35 | 4.61 | +2.10% | |
| 4.51 | 4.60 | 4.43 | 4.52 | -1.20% | |
| 4.70 | 4.70 | 4.53 | 4.57 | -0.44% | |
| 4.52 | 4.77 | 4.51 | 4.59 | +0.44% | |
| 4.37 | 4.59 | 4.30 | 4.57 | +1.78% | |
| 4.56 | 4.60 | 4.42 | 4.49 | -3.23% | |
| 4.50 | 4.70 | 4.48 | 4.64 | +2.43% | |
| 4.49 | 4.61 | 4.44 | 4.53 | 0.00% | |
| 4.45 | 4.62 | 4.45 | 4.53 | 0.00% | |
| 4.48 | 4.61 | 4.45 | 4.53 | -0.88% | |
| 4.64 | 4.67 | 4.47 | 4.57 | -2.14% | |
| 4.93 | 5.07 | 4.64 | 4.67 | -4.50% | |
| 4.86 | 4.99 | 4.81 | 4.89 | +1.03% | |
| 4.69 | 4.86 | 4.64 | 4.84 | +2.98% | |
| 4.75 | 4.79 | 4.60 | 4.70 | -1.88% | |
| 4.61 | 4.83 | 4.52 | 4.79 | +3.01% | |
| 4.55 | 4.76 | 4.51 | 4.65 | +1.53% | |
| 4.54 | 4.68 | 4.47 | 4.58 | +0.66% | |
| 4.69 | 4.80 | 4.45 | 4.55 | -2.15% | |
| 4.73 | 4.74 | 4.47 | 4.65 | -0.21% | |
| 4.50 | 4.71 | 4.37 | 4.66 | +4.02% | |
| 4.62 | 4.64 | 4.46 | 4.48 | -2.82% | |
| 4.62 | 4.65 | 4.47 | 4.61 | 0.00% | |
| 4.60 | 4.70 | 4.44 | 4.61 | +4.54% | |
| 4.50 | 4.61 | 4.40 | 4.41 | -2.86% | |
| 4.75 | 4.81 | 4.47 | 4.54 | -3.81% | |
| 4.65 | 4.86 | 4.63 | 4.72 | +1.29% | |
| 4.52 | 4.75 | 4.51 | 4.66 | +3.33% | |
| 4.51 | 4.68 | 4.48 | 4.51 | -1.31% | |
| 4.49 | 4.61 | 4.49 | 4.57 | +2.01% | |
| 4.74 | 4.77 | 4.43 | 4.48 | -5.88% | |
| 4.72 | 4.89 | 4.66 | 4.76 | +0.85% | |
| 4.68 | 4.73 | 4.50 | 4.72 | +1.29% | |
| 5.00 | 5.04 | 4.64 | 4.66 | -8.45% | |
| 4.78 | 5.13 | 4.75 | 5.09 | +6.49% | |
| 4.66 | 4.82 | 4.56 | 4.78 | +3.02% | |
| 4.51 | 4.66 | 4.40 | 4.64 | +1.75% | |
| 4.93 | 4.97 | 4.49 | 4.56 | -6.94% | |
| 5.04 | 5.12 | 4.84 | 4.90 | -2.78% | |
| 4.88 | 5.17 | 4.85 | 5.04 | +2.86% | |
| 4.88 | 4.94 | 4.68 | 4.90 | +0.82% | |
| 4.91 | 4.92 | 4.56 | 4.86 | -2.41% | |
| 5.14 | 5.19 | 4.92 | 4.98 | -3.11% | |
| 5.20 | 5.27 | 5.02 | 5.14 | -3.20% | |
| 5.31 | 5.69 | 5.22 | 5.31 | +0.95% | |
| 4.89 | 5.30 | 4.80 | 5.26 | +7.57% | |
| 5.45 | 5.53 | 4.88 | 4.89 | -6.86% | |
| 5.51 | 5.53 | 5.16 | 5.25 | -4.55% | |
| 5.66 | 5.68 | 5.47 | 5.50 | -2.83% | |
| 5.65 | 5.69 | 5.59 | 5.66 | +0.18% | |
| 5.80 | 5.81 | 5.58 | 5.65 | -3.09% | |
| 5.90 | 5.90 | 5.71 | 5.83 | -1.35% | |
| 5.92 | 6.02 | 5.86 | 5.91 | +3.50% | |
| 5.77 | 5.84 | 5.69 | 5.71 | -2.56% | |
| 5.55 | 5.96 | 5.52 | 5.86 | +6.74% | |
| 5.45 | 5.71 | 5.42 | 5.49 | +0.73% | |
| 5.54 | 5.72 | 5.37 | 5.45 | +0.18% | |
| 5.77 | 5.89 | 5.42 | 5.44 | -6.53% | |
| 5.71 | 5.91 | 5.71 | 5.82 | +1.04% | |
| 5.85 | 5.95 | 5.73 | 5.76 | -0.52% | |
| 5.76 | 5.95 | 5.70 | 5.79 | +0.52% | |
| 5.57 | 5.81 | 5.46 | 5.76 | +3.60% | |
| 5.27 | 5.64 | 5.22 | 5.56 | +4.71% | |
| 5.40 | 5.53 | 5.30 | 5.31 | -2.57% | |
| 5.12 | 5.54 | 5.10 | 5.45 | +7.92% | |
| 5.13 | 5.24 | 5.01 | 5.05 | -0.20% | |
| 4.82 | 5.10 | 4.65 | 5.06 | +12.69% | |
| 4.10 | 4.52 | 4.10 | 4.49 | +10.59% | |
| 4.44 | 4.47 | 4.03 | 4.06 | -8.35% | |
| 4.61 | 4.64 | 4.42 | 4.43 | -6.54% | |
| 4.90 | 4.92 | 4.72 | 4.74 | -2.47% | |
| 4.64 | 4.89 | 4.61 | 4.86 | +5.88% | |
| 4.44 | 4.60 | 4.34 | 4.59 | +3.85% | |
| 4.23 | 4.44 | 4.23 | 4.42 | +5.49% | |
| 3.99 | 4.34 | 3.97 | 4.19 | +5.01% | |
| 4.16 | 4.22 | 3.92 | 3.99 | -0.50% | |
| 4.17 | 4.21 | 4.00 | 4.01 | -3.37% | |
| 4.12 | 4.34 | 4.05 | 4.15 | +0.73% | |
| 4.10 | 4.26 | 4.05 | 4.12 | -0.24% | |
| 3.90 | 4.28 | 3.90 | 4.13 | +2.99% | |
| 4.35 | 4.35 | 3.98 | 4.01 | -8.03% | |
| 4.35 | 4.50 | 4.20 | 4.36 | +1.87% | |
| 3.89 | 4.31 | 3.86 | 4.28 | +10.03% | |
| 3.89 | 4.00 | 3.75 | 3.89 | +1.57% | |
| 3.90 | 4.00 | 3.69 | 3.83 | -2.30% | |
| 4.03 | 4.08 | 3.89 | 3.92 | -2.73% | |
| 4.55 | 4.55 | 3.89 | 4.03 | -5.62% | |
| 4.29 | 4.54 | 4.00 | 4.27 | -4.26% | |
| 4.32 | 4.56 | 3.97 | 4.46 | -10.08% | |
| 4.91 | 5.20 | 4.85 | 4.96 | +1.02% | |
| 4.98 | 5.19 | 4.91 | 4.91 | -2.00% | |
| 4.99 | 5.25 | 4.90 | 5.01 | +0.40% | |
| 4.89 | 5.08 | 4.84 | 4.99 | +2.25% | |
| 4.81 | 4.94 | 4.70 | 4.88 | +2.74% | |
| 5.05 | 5.10 | 4.74 | 4.75 | -3.85% | |
| 4.97 | 5.20 | 4.91 | 4.94 | 0.00% | |
| 5.12 | 5.24 | 4.71 | 4.94 | -4.08% | |
| 4.93 | 5.33 | 4.81 | 5.15 | +9.11% | |
| 4.82 | 4.89 | 4.51 | 4.72 | 0.00% | |
| 4.90 | 4.92 | 4.43 | 4.72 | -7.09% | |
| 5.33 | 5.39 | 4.87 | 5.08 | -4.87% | |
| 5.34 | 5.51 | 5.22 | 5.34 | +3.59% | |
| 4.99 | 5.16 | 4.80 | 5.16 | +2.08% | |
| 4.88 | 5.15 | 4.86 | 5.05 | +3.48% | |
| 5.09 | 5.09 | 4.70 | 4.88 | -2.40% | |
| 5.06 | 5.21 | 4.93 | 5.00 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the TSHA chart for longer ranges.