Tyra Biosciences Stock Price History
NASDAQ: TYRAHealth CareBiotechnology: Pharmaceutical PreparationsUSD
At close: Oct 9, 4:00 PM ET · Delayed 15 min
TYRA price history at a glance
The price history for Tyra Biosciences (TYRA) on this page begins on September 13, 2021, when the stock closed at $19.91; it most recently closed at $19.94 on October 5, 2026. The highest price in this record is $40.65, reached on March 30, 2026; the latest close is 50.9% below that peak. Across the 4 complete calendar years in the table, TYRA finished higher in 3 and lower in 1. Its best year was 2023 (+82.2%) and its worst was 2022 (-46.0%).
Over roughly 5 years the share price changed +0.2%, a 0.0% compound annual price return (excluding dividends). In the last 12 months alone, TYRA has gained 47.5%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2021
- $40.65
- Date of high
- Mar 30, 2026
- Low since 2021
- $4.93
- Date of low
- Jun 20, 2022
- 52-week high
- $40.65
- 52-week low
- $13.35
- IPO year
- 2021
- Last close
- $19.94
TYRA returns
1 week
-2.40%
1 month
-9.40%
3 months
-39.11%
6 months
-43.45%
Year to date
-24.15%
1 year
+47.49%
3 years
+41.02%
5 years
+22.03%
TYRA price return, excluding dividends.
TYRA annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 19.94 | -25.57% |
| 2025 | 26.79 | +71.40% |
| 2024 | 15.63 | +12.85% |
| 2023 | 13.85 | +82.24% |
| 2022 | 7.60 | -45.98% |
| 2021* | 14.07 | -29.33% |
* Partial year: the record begins after the start of 2021; return measured from the first available close.
2026 return is year to date.
TYRA daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 19.93 | 20.59 | 19.73 | 19.94 | -0.15% | |
| 20.12 | 20.17 | 19.50 | 19.97 | -2.06% | |
| 19.97 | 20.79 | 19.80 | 20.39 | +0.74% | |
| 20.93 | 20.99 | 19.60 | 20.24 | -3.30% | |
| 20.57 | 21.03 | 19.94 | 20.93 | +2.45% | |
| 21.25 | 21.39 | 20.17 | 20.43 | -2.76% | |
| 21.78 | 22.32 | 20.88 | 21.01 | -3.93% | |
| 22.19 | 22.45 | 21.70 | 21.87 | -0.50% | |
| 21.37 | 22.62 | 21.29 | 21.98 | +2.47% | |
| 21.57 | 21.93 | 21.00 | 21.45 | -1.42% | |
| 22.33 | 22.41 | 21.67 | 21.76 | -2.90% | |
| 23.17 | 23.41 | 22.12 | 22.41 | -3.53% | |
| 25.27 | 25.39 | 22.86 | 23.23 | -9.15% | |
| 25.77 | 26.43 | 25.20 | 25.57 | -0.31% | |
| 26.04 | 26.96 | 25.40 | 25.65 | -0.31% | |
| 24.58 | 25.88 | 24.40 | 25.73 | +5.32% | |
| 24.80 | 25.17 | 24.27 | 24.43 | +0.33% | |
| 25.58 | 26.15 | 24.15 | 24.35 | -4.25% | |
| 24.71 | 25.78 | 24.15 | 25.43 | +1.44% | |
| 23.20 | 26.36 | 23.20 | 25.07 | +13.80% | |
| 23.63 | 23.96 | 21.86 | 22.03 | -6.41% | |
| 21.41 | 23.64 | 21.27 | 23.54 | +6.95% | |
| 18.94 | 22.30 | 18.66 | 22.01 | -17.66% | |
| 27.95 | 29.49 | 26.70 | 26.73 | -6.70% | |
| 24.51 | 29.56 | 24.51 | 28.65 | +15.25% | |
| 25.22 | 25.59 | 24.61 | 24.86 | -1.07% | |
| 25.52 | 26.42 | 24.80 | 25.13 | -0.67% | |
| 24.99 | 25.59 | 24.84 | 25.30 | +1.08% | |
| 24.82 | 25.21 | 24.17 | 25.03 | +0.36% | |
| 25.88 | 25.88 | 24.91 | 24.94 | -4.55% | |
| 26.17 | 26.69 | 25.92 | 26.13 | -0.34% | |
| 26.63 | 26.79 | 26.03 | 26.22 | -1.76% | |
| 26.47 | 26.99 | 26.30 | 26.69 | +2.30% | |
| 25.99 | 26.42 | 25.18 | 26.09 | +0.15% | |
| 25.95 | 26.81 | 25.95 | 26.05 | +1.40% | |
| 26.36 | 26.36 | 25.08 | 25.69 | -4.18% | |
| 26.69 | 26.98 | 26.27 | 26.81 | +2.96% | |
| 26.30 | 26.71 | 25.63 | 26.04 | -0.69% | |
| 25.00 | 27.06 | 24.98 | 26.22 | +3.68% | |
| 24.92 | 25.53 | 24.61 | 25.29 | +1.08% | |
| 25.33 | 25.45 | 24.83 | 25.02 | -1.11% | |
| 25.49 | 25.65 | 24.89 | 25.30 | +0.48% | |
| 26.25 | 26.45 | 24.75 | 25.18 | -4.08% | |
| 26.42 | 26.81 | 25.92 | 26.25 | -0.98% | |
| 27.38 | 27.82 | 26.14 | 26.51 | -1.67% | |
| 25.69 | 27.33 | 25.68 | 26.96 | +4.86% | |
| 29.00 | 30.59 | 25.46 | 25.71 | -20.97% | |
| 32.21 | 32.99 | 31.92 | 32.53 | +1.53% | |
| 31.06 | 32.56 | 30.82 | 32.04 | +0.50% | |
| 33.06 | 33.06 | 31.12 | 31.88 | -3.57% | |
| 31.39 | 33.26 | 31.06 | 33.06 | +6.27% | |
| 31.32 | 31.80 | 30.16 | 31.11 | +0.74% | |
| 31.21 | 31.71 | 30.38 | 30.88 | -0.58% | |
| 30.79 | 32.26 | 30.79 | 31.06 | +1.40% | |
| 31.08 | 31.08 | 30.02 | 30.63 | -0.55% | |
| 30.13 | 30.80 | 29.70 | 30.80 | +0.69% | |
| 32.27 | 32.27 | 30.55 | 30.59 | -3.96% | |
| 31.07 | 31.96 | 31.05 | 31.85 | +2.56% | |
| 32.00 | 33.05 | 31.03 | 31.06 | -3.35% | |
| 31.14 | 33.72 | 30.08 | 32.13 | +1.65% | |
| 31.98 | 32.65 | 31.24 | 31.61 | -2.38% | |
| 32.54 | 33.43 | 31.62 | 32.38 | -1.52% | |
| 32.61 | 33.15 | 31.80 | 32.88 | +0.64% | |
| 32.16 | 33.12 | 31.40 | 32.67 | -0.24% | |
| 32.80 | 33.27 | 31.09 | 32.75 | -0.79% | |
| 32.23 | 33.12 | 31.93 | 33.01 | +1.35% | |
| 31.90 | 32.84 | 31.43 | 32.57 | +1.97% | |
| 31.06 | 32.76 | 30.29 | 31.94 | +3.50% | |
| 30.72 | 31.62 | 30.01 | 30.86 | +0.78% | |
| 29.71 | 30.78 | 29.33 | 30.62 | +4.11% | |
| 31.92 | 32.30 | 29.27 | 29.41 | -7.92% | |
| 32.59 | 32.62 | 31.41 | 31.94 | -0.53% | |
| 31.71 | 32.30 | 30.93 | 32.11 | +0.72% | |
| 30.92 | 32.26 | 30.08 | 31.88 | +3.04% | |
| 30.34 | 31.57 | 30.21 | 30.94 | +1.88% | |
| 30.01 | 31.21 | 29.68 | 30.37 | +1.03% | |
| 29.44 | 31.30 | 28.87 | 30.06 | -0.27% | |
| 28.63 | 30.40 | 28.06 | 30.14 | +6.43% | |
| 29.98 | 30.09 | 27.98 | 28.32 | -2.58% | |
| 28.83 | 29.60 | 28.48 | 29.07 | +3.05% | |
| 28.55 | 29.31 | 27.62 | 28.21 | -1.19% | |
| 27.19 | 28.57 | 26.58 | 28.55 | +5.78% | |
| 25.64 | 27.58 | 25.01 | 26.99 | +5.55% | |
| 25.51 | 26.56 | 24.66 | 25.57 | +0.59% | |
| 26.19 | 27.06 | 25.13 | 25.42 | -2.00% | |
| 27.24 | 27.29 | 25.22 | 25.94 | -3.03% | |
| 26.31 | 27.11 | 26.00 | 26.75 | +0.41% | |
| 27.11 | 27.79 | 26.41 | 26.64 | -1.99% | |
| 28.69 | 29.61 | 26.44 | 27.18 | -5.26% | |
| 28.51 | 29.81 | 28.40 | 28.69 | +0.10% | |
| 30.02 | 30.02 | 28.49 | 28.66 | -5.69% | |
| 33.35 | 33.35 | 29.65 | 30.39 | -9.04% | |
| 32.68 | 33.91 | 32.20 | 33.41 | +2.23% | |
| 33.36 | 33.68 | 32.18 | 32.68 | -1.48% | |
| 33.37 | 34.50 | 32.75 | 33.17 | -1.25% | |
| 32.75 | 33.65 | 32.37 | 33.59 | +3.45% | |
| 33.06 | 33.45 | 32.16 | 32.47 | -1.67% | |
| 32.99 | 33.59 | 32.56 | 33.02 | -1.14% | |
| 34.19 | 34.82 | 33.37 | 33.40 | -1.12% | |
| 35.08 | 35.62 | 33.73 | 33.78 | -5.27% | |
| 37.02 | 37.22 | 34.82 | 35.66 | -3.73% | |
| 35.81 | 37.27 | 34.84 | 37.04 | +1.45% | |
| 36.03 | 37.03 | 35.17 | 36.51 | +0.88% | |
| 34.87 | 36.31 | 34.20 | 36.19 | +3.79% | |
| 33.80 | 35.08 | 33.01 | 34.87 | +2.53% | |
| 34.38 | 35.14 | 33.41 | 34.01 | -0.90% | |
| 32.95 | 34.57 | 32.94 | 34.32 | +4.32% | |
| 33.80 | 33.80 | 32.26 | 32.90 | -2.66% | |
| 33.91 | 34.98 | 32.89 | 33.80 | -0.38% | |
| 35.00 | 35.54 | 33.03 | 33.93 | -3.44% | |
| 34.04 | 35.55 | 33.64 | 35.14 | +3.23% | |
| 34.77 | 35.68 | 33.78 | 34.04 | -2.04% | |
| 34.24 | 35.45 | 33.99 | 34.75 | +2.86% | |
| 34.92 | 36.37 | 33.30 | 33.79 | -3.64% | |
| 37.00 | 38.43 | 34.56 | 35.06 | -5.04% | |
| 37.63 | 38.63 | 36.48 | 36.92 | -1.78% | |
| 36.51 | 37.72 | 35.43 | 37.59 | +2.45% | |
| 37.29 | 37.90 | 36.33 | 36.69 | -1.77% | |
| 37.44 | 38.10 | 36.63 | 37.35 | +1.80% | |
| 34.23 | 36.74 | 33.61 | 36.69 | +6.75% | |
| 35.53 | 35.60 | 34.30 | 34.37 | -3.35% | |
| 35.55 | 36.60 | 33.87 | 35.56 | +1.25% | |
| 34.80 | 35.45 | 34.56 | 35.12 | +0.43% | |
| 35.43 | 36.67 | 34.87 | 34.97 | -0.85% | |
| 35.94 | 36.58 | 35.13 | 35.27 | -0.98% | |
| 35.62 | 36.63 | 35.19 | 35.62 | +1.02% | |
| 36.68 | 36.99 | 34.94 | 35.26 | -3.90% | |
| 37.00 | 38.29 | 36.47 | 36.69 | -1.19% | |
| 38.19 | 39.32 | 36.79 | 37.13 | -1.59% | |
| 38.63 | 39.30 | 37.13 | 37.73 | -3.08% | |
| 39.62 | 40.51 | 38.72 | 38.93 | -1.72% | |
| 37.16 | 40.00 | 37.10 | 39.61 | +3.47% | |
| 39.10 | 40.65 | 37.95 | 38.28 | -0.05% | |
| 35.99 | 38.45 | 34.84 | 38.30 | +10.69% | |
| 36.51 | 36.57 | 34.01 | 34.60 | -4.66% | |
| 37.72 | 38.39 | 36.18 | 36.29 | -4.58% | |
| 36.00 | 38.86 | 36.00 | 38.03 | +3.60% | |
| 37.61 | 38.27 | 36.68 | 36.71 | +1.09% | |
| 36.34 | 36.58 | 35.00 | 36.32 | -0.56% | |
| 37.53 | 38.91 | 34.85 | 36.52 | -1.70% | |
| 38.67 | 39.15 | 37.13 | 37.15 | -2.70% | |
| 37.74 | 38.56 | 36.95 | 38.18 | +0.34% | |
| 37.56 | 38.53 | 36.50 | 38.05 | +0.34% | |
| 36.81 | 38.01 | 36.43 | 37.92 | +2.46% | |
| 36.27 | 37.84 | 36.27 | 37.01 | +2.18% | |
| 36.04 | 36.96 | 34.00 | 36.22 | +0.61% | |
| 36.04 | 36.38 | 34.52 | 36.00 | -1.48% | |
| 34.00 | 36.59 | 34.00 | 36.54 | +5.18% | |
| 33.64 | 35.09 | 33.64 | 34.74 | +2.93% | |
| 34.76 | 35.65 | 33.21 | 33.75 | -3.68% | |
| 34.48 | 35.37 | 33.53 | 35.04 | +1.45% | |
| 34.59 | 35.17 | 32.95 | 34.54 | -2.07% | |
| 32.00 | 35.96 | 30.47 | 35.27 | +6.85% | |
| 31.40 | 33.51 | 30.10 | 33.01 | +1.51% | |
| 32.02 | 33.54 | 31.52 | 32.52 | -2.37% | |
| 32.80 | 33.72 | 32.01 | 33.31 | +0.39% | |
| 34.50 | 34.54 | 31.83 | 33.18 | -3.83% | |
| 34.00 | 35.71 | 33.87 | 34.50 | +1.83% | |
| 33.95 | 34.07 | 32.84 | 33.88 | +1.74% | |
| 31.50 | 33.63 | 31.45 | 33.30 | +5.45% | |
| 31.10 | 31.61 | 30.00 | 31.58 | +0.80% | |
| 28.79 | 31.35 | 28.67 | 31.33 | +6.56% | |
| 29.33 | 29.94 | 28.64 | 29.40 | +0.96% | |
| 28.07 | 29.43 | 27.50 | 29.12 | +4.04% | |
| 29.41 | 30.26 | 27.82 | 27.99 | -4.11% | |
| 33.81 | 33.99 | 24.88 | 29.19 | -2.70% | |
| 31.41 | 32.29 | 28.18 | 30.00 | -4.46% | |
| 31.14 | 32.26 | 30.08 | 31.40 | +2.95% | |
| 31.03 | 31.03 | 29.47 | 30.50 | -1.61% | |
| 30.30 | 31.39 | 29.51 | 31.00 | +5.23% | |
| 30.31 | 31.27 | 29.39 | 29.46 | -4.26% | |
| 31.38 | 31.38 | 29.51 | 30.77 | -1.50% | |
| 31.72 | 32.37 | 30.27 | 31.24 | +0.71% | |
| 30.65 | 31.43 | 30.36 | 31.02 | +0.65% | |
| 31.91 | 32.14 | 30.07 | 30.82 | -4.70% | |
| 31.36 | 32.39 | 30.66 | 32.34 | +4.05% | |
| 31.85 | 31.85 | 30.63 | 31.08 | -1.02% | |
| 30.27 | 32.44 | 29.72 | 31.40 | +4.08% | |
| 30.11 | 30.86 | 28.51 | 30.17 | -0.66% | |
| 31.51 | 31.56 | 28.93 | 30.37 | -1.75% | |
| 29.69 | 31.43 | 29.30 | 30.91 | +5.03% | |
| 29.43 | 30.39 | 28.82 | 29.43 | -0.27% | |
| 28.31 | 31.16 | 27.40 | 29.51 | +2.57% | |
| 29.16 | 29.46 | 28.15 | 28.77 | -0.86% | |
| 29.14 | 29.78 | 28.71 | 29.02 | -0.62% | |
| 28.77 | 29.53 | 28.22 | 29.20 | +1.35% | |
| 28.77 | 29.03 | 27.50 | 28.81 | +0.14% | |
| 29.23 | 29.45 | 27.85 | 28.77 | -1.84% | |
| 30.70 | 30.70 | 29.03 | 29.31 | -3.43% | |
| 29.96 | 30.62 | 28.72 | 30.35 | +0.73% | |
| 26.63 | 30.39 | 26.21 | 30.13 | +14.13% | |
| 26.25 | 27.02 | 25.88 | 26.40 | +0.42% | |
| 26.79 | 26.87 | 24.95 | 26.29 | -1.87% | |
| 26.28 | 27.66 | 25.99 | 26.79 | +1.90% | |
| 25.46 | 26.41 | 25.36 | 26.29 | +3.34% | |
| 25.35 | 25.63 | 25.05 | 25.44 | -0.12% | |
| 25.73 | 26.17 | 24.88 | 25.47 | -1.89% | |
| 26.03 | 26.18 | 25.45 | 25.96 | -0.31% | |
| 26.00 | 26.34 | 25.66 | 26.04 | +0.81% | |
| 25.21 | 26.03 | 24.65 | 25.83 | +1.77% | |
| 25.50 | 26.09 | 25.10 | 25.38 | -0.51% | |
| 23.04 | 25.88 | 23.00 | 25.51 | +10.96% | |
| 22.71 | 23.39 | 22.63 | 22.99 | +1.73% | |
| 23.00 | 23.74 | 22.43 | 22.60 | -1.61% | |
| 22.56 | 23.60 | 22.48 | 22.97 | +3.84% | |
| 22.81 | 23.74 | 21.65 | 22.12 | -2.25% | |
| 22.97 | 23.39 | 22.06 | 22.63 | -0.79% | |
| 22.46 | 24.05 | 22.05 | 22.81 | +2.33% | |
| 22.10 | 22.52 | 21.81 | 22.29 | +0.77% | |
| 22.58 | 22.78 | 21.66 | 22.12 | -2.98% | |
| 21.76 | 23.23 | 21.72 | 22.80 | +6.05% | |
| 22.31 | 22.74 | 21.43 | 21.50 | -2.76% | |
| 21.52 | 22.13 | 21.43 | 22.11 | +1.89% | |
| 21.16 | 22.03 | 20.50 | 21.70 | +3.73% | |
| 20.84 | 21.17 | 20.08 | 20.92 | +0.53% | |
| 20.88 | 21.98 | 20.59 | 20.81 | -7.76% | |
| 22.29 | 22.83 | 21.69 | 22.56 | +2.41% | |
| 21.74 | 22.26 | 20.94 | 22.03 | +0.59% | |
| 22.34 | 22.68 | 21.68 | 21.90 | -1.62% | |
| 21.11 | 22.54 | 20.43 | 22.26 | +5.40% | |
| 20.74 | 21.81 | 19.18 | 21.12 | +0.57% | |
| 16.86 | 21.20 | 16.86 | 21.00 | +26.35% | |
| 16.07 | 16.68 | 15.94 | 16.62 | +3.62% | |
| 15.43 | 16.25 | 14.84 | 16.04 | +0.88% | |
| 15.69 | 17.21 | 15.35 | 15.90 | +1.08% | |
| 15.24 | 16.13 | 15.06 | 15.73 | +0.90% | |
| 15.29 | 16.03 | 14.67 | 15.59 | +0.71% | |
| 15.20 | 15.74 | 14.85 | 15.48 | +2.31% | |
| 14.49 | 15.38 | 13.83 | 15.13 | +4.34% | |
| 14.61 | 15.23 | 14.30 | 14.50 | +1.26% | |
| 14.50 | 14.60 | 13.86 | 14.32 | +0.28% | |
| 14.73 | 15.38 | 13.35 | 14.28 | -3.64% | |
| 15.01 | 15.26 | 14.56 | 14.82 | -1.20% | |
| 14.74 | 15.72 | 14.54 | 15.00 | -2.79% | |
| 15.68 | 15.99 | 14.83 | 15.43 | -2.59% | |
| 15.57 | 16.05 | 15.13 | 15.84 | +1.02% | |
| 15.16 | 15.77 | 15.10 | 15.68 | +2.89% | |
| 14.55 | 15.54 | 14.44 | 15.24 | +4.67% | |
| 14.82 | 14.90 | 14.32 | 14.56 | -1.89% | |
| 14.34 | 14.84 | 14.22 | 14.84 | +4.29% | |
| 14.39 | 14.99 | 14.15 | 14.23 | +0.78% | |
| 13.92 | 14.23 | 13.75 | 14.12 | +0.93% | |
| 14.68 | 15.01 | 13.96 | 13.99 | -4.89% | |
| 14.94 | 15.49 | 14.61 | 14.71 | -2.06% | |
| 14.73 | 15.04 | 14.49 | 15.02 | +3.59% | |
| 14.66 | 15.04 | 14.28 | 14.50 | -2.29% | |
| 15.52 | 15.60 | 14.82 | 14.84 | -3.01% | |
| 13.98 | 15.52 | 13.98 | 15.30 | +9.91% | |
| 14.28 | 14.46 | 13.82 | 13.92 | -3.06% | |
| 13.65 | 14.41 | 13.50 | 14.36 | +6.21% | |
| 13.87 | 13.91 | 13.29 | 13.52 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the TYRA chart for longer ranges.