Vertex Pharmaceuticals Stock Price History
NASDAQ: VRTXHealth CareBiotechnology: Pharmaceutical PreparationsUSD
510.08+6.83 (+1.36%)
At close: Oct 9, 4:00 PM ET · Delayed 15 min
After hours: 510.08 0.00%
VRTX price history at a glance
The price history for Vertex Pharmaceuticals (VRTX) on this page begins on July 22, 1991, when the stock closed at $4.50; it most recently closed at $503.25 on October 5, 2026. The highest price in this record is $560.25, reached on August 31, 2026; the latest close is 10.2% below that peak. Across the 34 complete calendar years in the table, VRTX finished higher in 22 and lower in 12. Its best year was 2000 (+308.6%) and its worst was 2001 (-66.5%).
Over roughly 35 years the share price changed +11083.3%, a 14.3% compound annual price return (excluding dividends). In the last 12 months alone, VRTX has gained 19.5%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 1991
- $560.25
- Date of high
- Aug 31, 2026
- Low since 1991
- $3.25
- Date of low
- Feb 22, 1993
- 52-week high
- $560.25
- 52-week low
- $402.58
- IPO year
- 1991
- Last close
- $503.25
VRTX returns
1 week
-0.69%
1 month
-4.85%
3 months
+1.36%
6 months
+12.64%
Year to date
+11.00%
1 year
+19.49%
3 years
+35.65%
5 years
+176.86%
VRTX price return, excluding dividends.
VRTX annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 503.25 | +11.31% |
| 2025 | 452.13 | +11.06% |
| 2024 | 407.11 | +0.05% |
| 2023 | 406.89 | +40.90% |
| 2022 | 288.78 | +31.50% |
| 2021 | 219.60 | -7.08% |
| 2020 | 236.34 | +8.42% |
| 2019 | 217.98 | +26.22% |
| 2018 | 172.70 | +15.24% |
| 2017 | 149.86 | +103.42% |
| 2016 | 73.67 | -41.45% |
| 2015 | 125.83 | +2.24% |
| 2014 | 123.07 | +67.56% |
| 2013 | 73.45 | +60.20% |
| 2012 | 45.85 | +38.06% |
| 2011 | 33.21 | -5.20% |
| 2010 | 35.03 | -18.25% |
| 2009 | 42.85 | +39.62% |
| 2008 | 30.69 | +42.74% |
| 2007 | 21.50 | -42.54% |
| 2006 | 37.42 | +35.24% |
| 2005 | 27.67 | +161.78% |
| 2004 | 10.57 | +0.67% |
| 2003 | 10.50 | -34.33% |
| 2002 | 15.99 | -33.24% |
| 2001 | 23.95 | -66.50% |
| 2000 | 71.50 | +308.57% |
| 1999 | 17.50 | +17.65% |
| 1998 | 14.88 | -10.86% |
| 1997 | 16.69 | -13.03% |
| 1996 | 19.19 | +44.81% |
| 1995 | 13.25 | +76.67% |
| 1994 | 7.50 | -18.92% |
| 1993 | 9.25 | +89.74% |
| 1992 | 4.88 | -40.00% |
| 1991* | 8.13 | +80.56% |
* Partial year: the record begins after the start of 1991; return measured from the first available close.
2026 return is year to date.
VRTX daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 503.14 | 507.87 | 498.90 | 503.25 | -0.47% | |
| 504.30 | 511.47 | 503.94 | 505.64 | +0.66% | |
| 505.00 | 507.41 | 496.33 | 502.31 | -0.24% | |
| 504.78 | 506.01 | 496.15 | 503.50 | -0.24% | |
| 509.50 | 509.50 | 499.95 | 504.73 | -0.40% | |
| 522.39 | 523.52 | 505.27 | 506.74 | -3.07% | |
| 525.26 | 529.72 | 522.74 | 522.81 | -0.74% | |
| 522.22 | 529.46 | 519.25 | 526.73 | -0.18% | |
| 524.27 | 529.89 | 521.16 | 527.67 | +0.28% | |
| 522.55 | 527.69 | 518.92 | 526.19 | +0.73% | |
| 515.56 | 528.99 | 515.30 | 522.38 | +1.17% | |
| 515.60 | 525.43 | 509.56 | 516.34 | +0.26% | |
| 521.69 | 525.97 | 508.14 | 514.99 | +0.84% | |
| 506.85 | 514.10 | 501.01 | 510.72 | +0.47% | |
| 516.34 | 518.10 | 505.01 | 508.34 | -1.55% | |
| 518.35 | 519.07 | 510.20 | 516.34 | +0.60% | |
| 513.80 | 517.95 | 511.35 | 513.26 | -0.27% | |
| 519.94 | 519.94 | 511.00 | 514.63 | -0.94% | |
| 522.17 | 525.29 | 514.66 | 519.51 | +0.79% | |
| 522.10 | 522.10 | 511.81 | 515.44 | +0.17% | |
| 519.13 | 522.60 | 514.32 | 514.56 | -1.26% | |
| 524.00 | 528.17 | 520.08 | 521.12 | -1.47% | |
| 529.64 | 535.00 | 520.20 | 528.90 | -3.15% | |
| 549.50 | 556.99 | 544.48 | 546.12 | -2.12% | |
| 559.00 | 560.25 | 551.61 | 557.96 | +0.22% | |
| 552.42 | 558.36 | 549.07 | 556.75 | +1.66% | |
| 548.60 | 551.40 | 545.08 | 547.65 | +0.57% | |
| 535.38 | 546.84 | 532.23 | 544.52 | +0.52% | |
| 547.09 | 549.57 | 540.08 | 541.69 | -1.07% | |
| 540.08 | 550.83 | 540.08 | 547.55 | +0.05% | |
| 549.84 | 553.47 | 546.24 | 547.29 | -1.01% | |
| 545.53 | 555.69 | 543.75 | 552.85 | +0.96% | |
| 548.98 | 550.62 | 542.42 | 547.59 | -0.08% | |
| 545.10 | 555.32 | 540.70 | 548.05 | +1.44% | |
| 543.78 | 548.99 | 538.27 | 540.26 | -2.14% | |
| 537.47 | 553.69 | 532.55 | 552.06 | +4.52% | |
| 520.00 | 533.78 | 517.34 | 528.19 | +2.45% | |
| 503.87 | 517.84 | 502.53 | 515.55 | +1.94% | |
| 511.41 | 513.64 | 502.29 | 505.75 | -2.07% | |
| 528.68 | 529.00 | 515.74 | 516.44 | -1.77% | |
| 527.00 | 531.22 | 520.08 | 525.73 | -0.74% | |
| 525.02 | 532.23 | 522.01 | 529.65 | +1.10% | |
| 539.50 | 546.17 | 519.82 | 523.91 | +5.61% | |
| 487.11 | 497.40 | 482.10 | 496.07 | +2.49% | |
| 490.91 | 492.40 | 480.86 | 484.03 | -0.17% | |
| 487.52 | 491.95 | 479.02 | 484.83 | +1.28% | |
| 471.29 | 488.04 | 465.51 | 478.71 | +1.70% | |
| 480.00 | 483.36 | 468.14 | 470.72 | -1.34% | |
| 480.67 | 480.67 | 469.87 | 477.10 | -0.95% | |
| 474.10 | 482.15 | 470.54 | 481.70 | -0.34% | |
| 492.67 | 492.99 | 481.91 | 483.33 | -1.44% | |
| 483.13 | 493.61 | 482.86 | 490.39 | +2.38% | |
| 479.27 | 487.21 | 477.99 | 479.00 | +0.34% | |
| 476.05 | 484.00 | 472.58 | 477.36 | +0.90% | |
| 467.09 | 477.68 | 465.00 | 473.09 | +0.11% | |
| 482.32 | 483.66 | 471.58 | 472.57 | -1.96% | |
| 478.56 | 484.99 | 473.56 | 482.00 | +0.31% | |
| 485.65 | 491.23 | 478.48 | 480.50 | -1.06% | |
| 483.51 | 496.69 | 481.98 | 485.65 | -0.08% | |
| 480.00 | 487.30 | 476.25 | 486.03 | +1.88% | |
| 472.15 | 480.96 | 469.60 | 477.08 | +0.16% | |
| 481.29 | 481.29 | 473.18 | 476.31 | -0.82% | |
| 486.18 | 486.18 | 474.71 | 480.25 | -1.06% | |
| 498.15 | 498.91 | 484.33 | 485.39 | -2.24% | |
| 495.58 | 500.77 | 482.11 | 496.50 | -0.39% | |
| 523.04 | 525.81 | 498.14 | 498.43 | -4.56% | |
| 530.00 | 533.67 | 512.77 | 522.25 | -1.39% | |
| 526.67 | 529.99 | 512.34 | 529.59 | +0.29% | |
| 503.76 | 529.14 | 501.53 | 528.04 | +6.03% | |
| 502.71 | 502.71 | 494.80 | 498.01 | +0.26% | |
| 500.49 | 500.99 | 489.62 | 496.73 | -0.58% | |
| 495.83 | 499.87 | 487.62 | 499.65 | +1.69% | |
| 482.50 | 503.89 | 482.20 | 491.34 | +2.32% | |
| 475.11 | 486.49 | 473.50 | 480.18 | +1.05% | |
| 471.38 | 480.86 | 469.93 | 475.20 | +1.45% | |
| 469.67 | 470.82 | 463.76 | 468.42 | +0.35% | |
| 455.65 | 468.18 | 453.21 | 466.79 | +3.36% | |
| 462.17 | 464.98 | 450.39 | 451.63 | -1.60% | |
| 449.67 | 464.31 | 447.54 | 458.99 | +1.28% | |
| 452.82 | 454.55 | 444.22 | 453.17 | +0.60% | |
| 446.69 | 453.68 | 439.50 | 450.46 | +1.24% | |
| 440.02 | 447.70 | 440.02 | 444.93 | -0.02% | |
| 437.51 | 445.78 | 435.21 | 445.04 | +2.14% | |
| 447.27 | 447.50 | 433.80 | 435.71 | -2.26% | |
| 447.02 | 449.50 | 440.90 | 445.77 | +0.63% | |
| 443.17 | 448.69 | 441.72 | 442.96 | -0.87% | |
| 445.61 | 453.16 | 443.86 | 446.83 | +1.15% | |
| 434.95 | 448.19 | 433.50 | 441.74 | +3.13% | |
| 420.63 | 429.01 | 420.01 | 428.34 | +0.76% | |
| 432.40 | 434.00 | 424.90 | 425.09 | -3.04% | |
| 439.91 | 443.54 | 433.26 | 438.40 | -2.04% | |
| 448.01 | 450.00 | 442.25 | 447.54 | -0.10% | |
| 434.08 | 449.29 | 434.08 | 447.97 | +2.46% | |
| 438.52 | 445.35 | 435.39 | 437.22 | +0.30% | |
| 437.99 | 441.99 | 433.79 | 435.93 | +0.32% | |
| 437.07 | 438.84 | 432.96 | 434.52 | +0.23% | |
| 429.36 | 434.76 | 426.01 | 433.54 | +0.72% | |
| 434.31 | 439.98 | 427.64 | 430.44 | -0.89% | |
| 436.79 | 444.32 | 433.15 | 434.31 | -0.52% | |
| 435.42 | 440.04 | 430.25 | 436.58 | -0.08% | |
| 453.45 | 453.45 | 435.86 | 436.95 | -2.99% | |
| 453.64 | 456.68 | 447.36 | 450.41 | -0.58% | |
| 446.47 | 455.32 | 444.26 | 453.06 | +1.06% | |
| 439.92 | 454.23 | 436.48 | 448.29 | +3.01% | |
| 429.50 | 442.16 | 428.50 | 435.17 | +1.24% | |
| 422.37 | 431.94 | 421.11 | 429.82 | +1.13% | |
| 425.13 | 429.61 | 423.59 | 425.00 | -0.62% | |
| 422.67 | 431.06 | 422.67 | 427.65 | +0.78% | |
| 431.99 | 433.94 | 412.27 | 424.36 | -1.28% | |
| 423.75 | 430.13 | 422.11 | 429.85 | +1.40% | |
| 425.02 | 427.38 | 421.54 | 423.92 | -0.81% | |
| 423.66 | 430.95 | 423.66 | 427.38 | +0.98% | |
| 424.44 | 426.72 | 419.71 | 423.24 | -1.60% | |
| 431.25 | 431.77 | 426.68 | 430.14 | +0.97% | |
| 427.01 | 434.07 | 425.87 | 426.01 | -0.99% | |
| 431.89 | 433.68 | 427.38 | 430.29 | -1.11% | |
| 440.71 | 442.04 | 433.81 | 435.10 | -0.59% | |
| 437.38 | 441.00 | 435.45 | 437.67 | +0.25% | |
| 437.12 | 440.32 | 429.65 | 436.59 | -0.59% | |
| 444.01 | 444.01 | 437.67 | 439.18 | -0.46% | |
| 441.55 | 443.90 | 437.58 | 441.20 | +1.27% | |
| 442.35 | 445.93 | 431.15 | 435.65 | -1.37% | |
| 444.15 | 447.82 | 437.19 | 441.70 | -0.58% | |
| 435.28 | 444.79 | 435.28 | 444.28 | +0.96% | |
| 434.17 | 445.11 | 433.68 | 440.05 | +0.87% | |
| 446.08 | 446.75 | 434.25 | 436.27 | -2.35% | |
| 439.77 | 447.00 | 436.35 | 446.78 | +0.64% | |
| 436.25 | 443.99 | 432.33 | 443.92 | +2.79% | |
| 435.50 | 435.50 | 425.26 | 431.86 | -0.56% | |
| 437.79 | 440.90 | 433.45 | 434.30 | -1.01% | |
| 447.55 | 449.62 | 436.56 | 438.71 | -1.91% | |
| 449.17 | 453.98 | 446.71 | 447.26 | +0.16% | |
| 443.43 | 448.35 | 442.09 | 446.54 | +0.76% | |
| 438.73 | 443.65 | 432.14 | 443.16 | +2.33% | |
| 450.95 | 452.00 | 431.01 | 433.07 | -4.56% | |
| 450.72 | 457.54 | 449.29 | 453.74 | -0.27% | |
| 449.14 | 459.37 | 449.14 | 454.97 | +1.42% | |
| 447.02 | 452.08 | 441.20 | 448.62 | -0.58% | |
| 458.42 | 463.78 | 450.97 | 451.24 | -0.61% | |
| 454.62 | 461.05 | 452.89 | 454.00 | -0.88% | |
| 454.50 | 459.46 | 449.75 | 458.05 | +1.43% | |
| 462.80 | 463.96 | 451.10 | 451.59 | -2.36% | |
| 468.40 | 468.45 | 461.50 | 462.49 | -0.77% | |
| 475.14 | 476.17 | 461.13 | 466.10 | -0.69% | |
| 481.79 | 486.66 | 469.08 | 469.34 | -1.84% | |
| 489.97 | 489.97 | 476.57 | 478.13 | -2.89% | |
| 497.88 | 499.50 | 488.79 | 492.38 | -1.36% | |
| 482.25 | 507.92 | 477.77 | 499.17 | +8.31% | |
| 455.59 | 461.26 | 450.78 | 460.87 | +0.92% | |
| 457.30 | 460.00 | 450.67 | 456.69 | -0.90% | |
| 476.64 | 480.00 | 457.00 | 460.82 | -3.57% | |
| 475.30 | 480.68 | 470.43 | 477.89 | +0.76% | |
| 478.95 | 484.10 | 471.58 | 474.27 | -2.42% | |
| 496.60 | 498.03 | 484.40 | 486.03 | -2.17% | |
| 480.31 | 497.80 | 479.75 | 496.83 | +3.48% | |
| 483.36 | 483.63 | 474.59 | 480.13 | -0.60% | |
| 486.35 | 492.28 | 481.71 | 483.05 | -0.90% | |
| 479.20 | 491.22 | 479.00 | 487.43 | +1.33% | |
| 475.08 | 487.60 | 475.08 | 481.01 | +0.86% | |
| 466.94 | 479.12 | 465.00 | 476.90 | +1.63% | |
| 469.83 | 472.24 | 463.00 | 469.27 | -0.22% | |
| 473.68 | 477.72 | 466.45 | 470.31 | -1.47% | |
| 489.46 | 494.05 | 473.45 | 477.32 | -2.88% | |
| 471.65 | 503.88 | 471.65 | 491.47 | +5.69% | |
| 462.00 | 469.00 | 460.00 | 465.02 | +0.82% | |
| 460.43 | 464.73 | 454.40 | 461.24 | -0.48% | |
| 469.83 | 474.57 | 462.24 | 463.48 | -1.57% | |
| 476.97 | 478.54 | 467.98 | 470.87 | -1.48% | |
| 459.69 | 478.28 | 459.00 | 477.92 | +4.17% | |
| 473.90 | 478.00 | 457.74 | 458.81 | -2.49% | |
| 470.49 | 478.72 | 467.10 | 470.52 | +1.05% | |
| 468.80 | 476.83 | 461.53 | 465.61 | -1.36% | |
| 466.79 | 473.74 | 464.01 | 472.01 | +0.45% | |
| 471.18 | 475.67 | 468.00 | 469.90 | -1.22% | |
| 479.03 | 484.35 | 473.86 | 475.68 | -0.47% | |
| 474.09 | 479.50 | 469.50 | 477.91 | +0.79% | |
| 476.80 | 485.00 | 470.49 | 474.17 | -0.56% | |
| 470.79 | 479.10 | 468.43 | 476.84 | +1.80% | |
| 465.23 | 470.34 | 462.74 | 468.41 | +0.23% | |
| 463.74 | 472.58 | 458.31 | 467.35 | +1.35% | |
| 440.54 | 465.15 | 439.91 | 461.14 | +4.31% | |
| 435.41 | 442.38 | 429.00 | 442.08 | +0.16% | |
| 440.46 | 445.77 | 437.46 | 441.36 | +0.56% | |
| 448.79 | 450.44 | 436.69 | 438.92 | -2.36% | |
| 454.58 | 455.03 | 446.01 | 449.53 | -1.13% | |
| 460.22 | 462.42 | 452.91 | 454.67 | -1.29% | |
| 461.07 | 464.59 | 454.54 | 460.59 | -0.70% | |
| 467.73 | 475.33 | 463.39 | 463.86 | -1.24% | |
| 481.51 | 485.69 | 465.28 | 469.68 | -2.99% | |
| 469.13 | 487.52 | 467.46 | 484.15 | +3.37% | |
| 454.85 | 471.28 | 453.69 | 468.38 | +4.36% | |
| 448.83 | 450.72 | 443.12 | 448.80 | -0.74% | |
| 454.34 | 455.99 | 448.52 | 452.13 | -0.27% | |
| 451.75 | 455.92 | 451.75 | 453.36 | -0.08% | |
| 456.83 | 458.36 | 453.40 | 453.74 | -1.31% | |
| 463.00 | 463.55 | 457.45 | 459.78 | -0.67% | |
| 462.67 | 463.65 | 460.86 | 462.90 | -0.02% | |
| 459.39 | 464.44 | 459.08 | 462.99 | +0.82% | |
| 460.44 | 461.49 | 457.04 | 459.21 | -0.24% | |
| 454.34 | 460.94 | 453.03 | 460.31 | +0.90% | |
| 446.86 | 460.40 | 445.51 | 456.20 | +1.97% | |
| 449.74 | 452.63 | 445.41 | 447.38 | -0.48% | |
| 453.83 | 456.05 | 447.31 | 449.52 | -1.20% | |
| 455.71 | 459.05 | 452.83 | 454.96 | -0.16% | |
| 454.28 | 456.46 | 449.48 | 455.71 | +0.81% | |
| 444.81 | 456.00 | 444.81 | 452.04 | +1.37% | |
| 445.65 | 448.33 | 442.07 | 445.93 | +0.29% | |
| 438.81 | 446.28 | 433.81 | 444.64 | +1.75% | |
| 442.55 | 448.28 | 436.49 | 437.01 | -1.14% | |
| 455.65 | 457.17 | 439.80 | 442.04 | -2.95% | |
| 457.78 | 462.00 | 454.46 | 455.48 | -0.41% | |
| 462.00 | 463.70 | 453.54 | 457.36 | -1.25% | |
| 440.31 | 463.85 | 439.35 | 463.13 | +6.92% | |
| 427.34 | 435.20 | 424.06 | 433.15 | +1.77% | |
| 431.92 | 434.00 | 423.46 | 425.60 | -1.85% | |
| 434.67 | 434.67 | 429.07 | 433.61 | +0.33% | |
| 432.43 | 433.32 | 428.07 | 432.17 | +0.55% | |
| 425.92 | 431.50 | 424.12 | 429.82 | +1.37% | |
| 426.23 | 432.55 | 423.87 | 424.00 | -0.65% | |
| 423.13 | 435.85 | 421.87 | 426.76 | +1.05% | |
| 420.84 | 431.13 | 420.00 | 422.32 | +0.31% | |
| 434.36 | 434.93 | 418.53 | 421.03 | -3.33% | |
| 434.00 | 437.79 | 430.15 | 435.52 | +0.35% | |
| 436.99 | 439.99 | 432.24 | 434.02 | -0.72% | |
| 440.02 | 442.22 | 433.67 | 437.15 | +0.61% | |
| 434.02 | 441.23 | 430.66 | 434.52 | +0.08% | |
| 429.69 | 435.94 | 425.46 | 434.19 | +1.16% | |
| 423.30 | 429.48 | 417.12 | 429.22 | +1.90% | |
| 412.38 | 422.23 | 410.50 | 421.20 | +2.86% | |
| 415.61 | 416.28 | 406.67 | 409.47 | -1.63% | |
| 414.10 | 424.25 | 410.29 | 416.25 | -0.18% | |
| 417.70 | 427.18 | 410.45 | 417.00 | -1.11% | |
| 418.55 | 430.71 | 403.16 | 421.67 | -1.02% | |
| 428.48 | 430.10 | 418.60 | 426.00 | +0.10% | |
| 416.28 | 426.96 | 415.76 | 425.57 | +1.35% | |
| 417.19 | 422.95 | 415.00 | 419.89 | +0.64% | |
| 418.02 | 422.98 | 415.77 | 417.21 | -1.23% | |
| 418.00 | 422.57 | 417.37 | 422.39 | +0.53% | |
| 422.00 | 423.61 | 418.76 | 420.17 | -0.29% | |
| 423.41 | 425.86 | 420.60 | 421.39 | -0.29% | |
| 427.85 | 432.76 | 421.26 | 422.63 | -0.89% | |
| 426.27 | 431.81 | 421.94 | 426.44 | +0.04% | |
| 417.57 | 426.97 | 417.57 | 426.27 | +1.71% | |
| 418.17 | 420.50 | 414.52 | 419.10 | +0.55% | |
| 407.36 | 419.37 | 406.76 | 416.81 | +2.01% | |
| 409.92 | 413.31 | 405.54 | 408.61 | +0.17% | |
| 412.17 | 413.57 | 407.05 | 407.90 | -1.05% | |
| 406.08 | 415.55 | 405.46 | 412.22 | +1.19% | |
| 404.21 | 409.47 | 402.58 | 407.37 | -0.10% | |
| 413.33 | 414.22 | 406.10 | 407.79 | -1.70% | |
| 419.31 | 421.01 | 414.28 | 414.86 | -1.49% | |
| 410.93 | 422.73 | 410.02 | 421.15 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the VRTX chart for longer ranges.