Vertex Pharmaceuticals (VRTX) Options Chain

NASDAQ: VRTXHealth CareBiotechnology: Pharmaceutical PreparationsUSD

510.08+6.83 (+1.36%)

At close: Oct 9, 4:00 PM ET · Delayed 15 min

Expiration date

Expiration: Oct 16, 2026
Days to expiration: 6
Share price: $510.08
Put/call ratio (OI): 0.89
Put/call ratio (volume): 0.45
ATM implied volatility: 40.6%
Expected move: ±$26.57
Open interest (C / P): 3.54K / 3.14K

VRTX options summary

The VRTX options chain for the October 16, 2026 expiration lists 49 call and 49 put contracts, with 6 days until expiration. Open interest stands at 3,540 calls and 3,136 puts, a put/call ratio of 0.89, which is fairly balanced between calls and puts. At-the-money implied volatility near the $510.00 strike is 40.6%, which implies the market expects a move of about ±$26.57 (5.2%) in Vertex Pharmaceuticals stock by expiration.

The most open interest sits at the $515.00 call (375 contracts) and the $500.00 put (698 contracts).

Summary generated from market data by MetaCap's automated system. Methodology

VRTX options chain · October 16, 2026

VRTX calls and puts by strike price. Shaded cells are in the money.
Calls							Puts
OI	Vol	IV	Last	Bid	Ask	Strike	Bid	Ask	Last	IV	Vol	OI
—	—	—	—	—	—	250.00	0.05	6.30	2.10	338.1%	—	2
—	—	—	—	—	—	260.00	0.00	7.50	1.29	333.2%	10	11
—	—	—	—	—	—	270.00	0.05	6.60	2.85	309.0%	1	9
0	—	—	159.29	0.00	0.00	280.00	0.05	6.00	3.20	288.0%	1	16
—	—	—	—	—	—	290.00	0.05	6.40	4.00	277.2%	1	9
—	—	—	—	—	—	300.00	0.00	0.00	5.50	50.0%	1	0
—	—	—	—	—	—	310.00	0.00	5.70	2.31	242.7%	3	8
0	1	199.1%	185.30	188.40	194.50	320.00	0.25	8.00	7.40	249.4%	—	1
—	—	—	—	—	—	330.00	0.00	0.00	0.79	50.0%	35	0
—	—	—	—	—	—	340.00	0.00	0.00	0.87	50.0%	35	0
—	—	—	—	—	—	350.00	0.00	4.90	0.05	186.1%	37	43
1	1	434.8%	127.90	183.80	192.10	360.00	0.00	5.40	2.45	178.3%	2	6
1	1	415.4%	107.69	174.20	182.20	370.00	0.00	4.90	0.30	163.2%	2	20
—	—	—	—	—	—	380.00	0.00	1.50	0.25	120.8%	1	11
0	1	390.6%	123.00	156.80	165.50	390.00	0.00	4.90	2.58	141.1%	2	77
2	1	85.0%	107.80	106.00	114.60	400.00	0.00	0.00	0.74	50.0%	8	0
—	—	—	—	—	—	410.00	0.00	4.90	1.23	119.8%	1	33
1	4	318.8%	73.20	125.10	132.00	420.00	0.00	0.00	1.11	25.0%	43	0
23	4	62.4%	74.00	76.00	84.60	430.00	0.00	4.90	2.22	99.0%	3	145
—	—	—	—	—	—	435.00	0.00	4.90	2.66	93.8%	1	1
0	1	—	97.00	0.00	0.00	440.00	0.00	4.90	0.60	88.7%	7	45
20	3	68.7%	61.15	58.50	64.60	450.00	0.00	4.90	1.50	78.4%	6	24
—	—	—	—	—	—	455.00	0.00	4.90	2.29	73.2%	—	10
15	3	82.9%	50.03	46.00	54.60	460.00	0.00	0.05	0.24	33.0%	22	23
—	—	—	—	—	—	465.00	0.00	0.60	0.45	44.3%	1	67
204	1	50.6%	39.20	38.60	44.70	470.00	0.00	2.20	0.65	55.8%	2	255
—	—	—	—	—	—	475.00	0.00	4.90	2.30	52.4%	26	29
65	1	61.4%	21.90	28.80	35.00	480.00	0.00	1.95	0.77	43.6%	20	222
1	—	56.7%	44.10	21.50	30.30	485.00	0.00	4.90	2.97	55.1%	1	3
—	—	—	—	—	—	487.50	0.00	4.90	5.43	51.9%	3	0
31	2	52.1%	37.76	19.40	25.70	490.00	0.05	6.30	0.85	55.3%	2	109
1	—	50.1%	27.20	17.10	23.50	492.50	—	—	—	—	—	—
2	2	48.4%	18.07	16.80	21.40	495.00	0.00	4.50	3.70	40.2%	4	18
3	—	46.5%	30.40	12.90	19.30	497.50	0.25	4.30	6.42	36.0%	1	1
97	1	45.2%	13.10	10.80	17.40	500.00	2.10	5.40	3.08	37.2%	21	698
15	1	43.5%	8.50	7.20	14.00	505.00	1.40	7.10	5.03	36.3%	1	7
128	5	43.2%	7.70	6.00	11.30	510.00	4.50	9.90	6.30	38.1%	12	230
VRTX $510.08
375	1	44.2%	1.70	1.70	9.30	515.00	5.30	12.50	15.50	37.6%	1	384
192	17	40.8%	3.40	0.05	6.50	520.00	8.90	15.70	17.00	37.8%	1	256
20	2	39.3%	2.30	0.00	4.60	525.00	13.00	19.00	10.60	37.0%	33	176
12	1	33.9%	14.59	0.00	2.85	527.50	15.10	21.00	26.51	37.5%	7	27
168	129	46.6%	1.81	0.90	4.90	530.00	17.40	23.00	27.53	37.8%	13	135
18	1	53.7%	3.16	0.00	5.20	535.00	21.80	28.00	15.32	43.0%	1	2
174	2	45.7%	0.75	0.00	2.70	540.00	26.40	32.60	37.30	45.6%	1	7
10	3	62.8%	4.60	0.00	4.90	545.00	—	—	—	—	—	—
314	10	50.0%	0.20	0.05	2.00	550.00	35.90	42.00	37.40	50.6%	5	11
11	1	57.4%	2.46	0.00	4.90	555.00	—	—	—	—	—	—
293	1	48.3%	0.55	0.00	0.95	560.00	45.80	51.90	49.00	58.0%	1	5
8	1	65.6%	2.63	0.00	4.90	565.00	—	—	—	—	—	—
369	23	54.5%	0.50	0.00	0.90	570.00	55.70	61.80	46.52	64.8%	2	0
12	1	73.4%	1.73	0.00	4.90	575.00	—	—	—	—	—	—
68	2	77.1%	0.10	0.00	4.90	580.00	65.70	71.80	65.85	72.1%	—	0
225	20	84.4%	2.42	0.00	4.90	590.00	—	—	—	—	—	—
134	5	69.2%	0.68	0.00	1.30	600.00	52.40	61.00	97.63	—	—	0
20	21	98.1%	0.78	0.00	4.90	610.00	—	—	—	—	—	—
203	3	104.7%	2.33	0.00	4.90	620.00	—	—	—	—	—	—
225	504	72.1%	0.40	0.00	0.40	630.00	—	—	—	—	—	—
19	10	117.2%	4.90	0.00	4.90	640.00	—	—	—	—	—	—
13	12	123.1%	1.00	0.00	4.90	650.00	—	—	—	—	—	—
18	23	128.9%	0.65	0.00	4.90	660.00	107.80	116.50	153.83	—	—	0
29	19	134.6%	0.45	0.00	4.90	670.00	—	—	—	—	—	—
0	1	50.0%	1.05	0.00	0.00	680.00	—	—	—	—	—	—
0	1	50.0%	0.90	0.00	0.00	700.00	—	—	—	—	—	—
0	1	50.0%	0.90	0.00	0.00	720.00	—	—	—	—	—	—
0	1	50.0%	0.90	0.00	0.00	740.00	—	—	—	—	—	—

In-the-money callsIn-the-money puts. IV = implied volatility, OI = open interest (contracts). Each contract covers 100 shares. Quotes delayed at least 15 minutes.

Frequently asked questions

What is the VRTX put/call ratio?

For the October 16, 2026 expiration, the VRTX put/call ratio based on open interest is 0.89 (3,136 puts vs 3,540 calls), and 0.45 based on today's volume. A ratio above 1 means more puts than calls.

What is VRTX's implied volatility?

At-the-money implied volatility for VRTX options expiring October 16, 2026 is about 40.6%, an annualized estimate of how much the market expects Vertex Pharmaceuticals stock to move.

How many VRTX option expiration dates are there?

VRTX has 14 listed expiration dates, from Oct 16, 2026 to Jan 19, 2029.

What does "in the money" mean?

A call is in the money when the strike price is below the current share price; a put is in the money when the strike is above it. In-the-money contracts have intrinsic value and are shaded in the table.