Xilio Therapeutics Stock Price History
NASDAQ: XLOHealth CareBiotechnology: Pharmaceutical PreparationsUSD
9.05+0.04 (+0.44%)
At close: Oct 9, 4:00 PM ET · Delayed 15 min
XLO price history at a glance
The price history for Xilio Therapeutics (XLO) on this page begins on October 18, 2021, when the stock closed at $224.00; it most recently closed at $9.05 on October 5, 2026. The highest price in this record is $391.30, reached on November 15, 2021; the latest close is 97.7% below that peak. Across the 4 complete calendar years in the table, XLO finished higher in 1 and lower in 3. Its best year was 2024 (+100.0%) and its worst was 2022 (-83.2%).
Over roughly 5 years the share price changed -96.0%, a -47.6% compound annual price return (excluding dividends). In the last 12 months alone, XLO has lost 22.9%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2021
- $391.30
- Date of high
- Nov 15, 2021
- Low since 2021
- $6.47
- Date of low
- Mar 9, 2026
- 52-week high
- $12.59
- 52-week low
- $6.47
- IPO year
- 2021
- Last close
- $9.05
XLO returns
1 week
+0.44%
1 month
+0.89%
3 months
-0.55%
6 months
+6.35%
Year to date
+1.00%
1 year
-22.86%
3 years
-63.06%
XLO price return, excluding dividends.
XLO annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 9.05 | -3.81% |
| 2025 | 9.41 | -38.91% |
| 2024 | 15.40 | +100.00% |
| 2023 | 7.70 | -79.55% |
| 2022 | 37.66 | -83.19% |
| 2021* | 224.00 | 0.00% |
* Partial year: the record begins after the start of 2021; return measured from the first available close.
2026 return is year to date.
XLO daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 8.82 | 9.16 | 8.82 | 9.05 | +0.44% | |
| 9.01 | 9.13 | 8.78 | 9.01 | 0.00% | |
| 9.01 | 9.01 | 9.01 | 9.01 | +0.11% | |
| 9.10 | 9.32 | 8.81 | 9.00 | -1.21% | |
| 9.07 | 9.49 | 9.07 | 9.11 | +1.11% | |
| 8.89 | 9.08 | 8.89 | 9.01 | +1.12% | |
| 8.97 | 9.12 | 8.79 | 8.91 | -1.55% | |
| 9.19 | 9.25 | 9.05 | 9.05 | +1.25% | |
| 9.57 | 9.57 | 8.94 | 8.94 | -1.24% | |
| 9.21 | 9.22 | 8.96 | 9.05 | +0.11% | |
| 9.00 | 9.21 | 8.93 | 9.04 | +0.44% | |
| 8.93 | 9.09 | 8.93 | 9.00 | +0.67% | |
| 9.03 | 9.04 | 8.94 | 8.94 | -1.11% | |
| 9.04 | 9.16 | 8.95 | 9.04 | +0.22% | |
| 8.96 | 9.18 | 8.96 | 9.02 | -1.20% | |
| 9.00 | 9.67 | 8.94 | 9.13 | +1.00% | |
| 9.00 | 9.05 | 8.93 | 9.04 | +0.67% | |
| 9.02 | 9.02 | 8.93 | 8.98 | -0.55% | |
| 8.93 | 9.03 | 8.93 | 9.03 | +1.12% | |
| 9.06 | 9.21 | 8.93 | 8.93 | 0.00% | |
| 8.93 | 9.49 | 8.93 | 8.93 | 0.00% | |
| 8.95 | 9.00 | 8.93 | 8.93 | -0.45% | |
| 8.91 | 9.00 | 8.80 | 8.97 | +0.67% | |
| 9.03 | 9.11 | 8.81 | 8.91 | -1.00% | |
| 9.23 | 9.23 | 8.81 | 9.00 | -0.22% | |
| 8.94 | 9.10 | 8.72 | 9.02 | +2.04% | |
| 9.14 | 9.14 | 8.84 | 8.84 | -0.45% | |
| 8.57 | 9.25 | 8.57 | 8.88 | -0.78% | |
| 9.00 | 9.27 | 8.90 | 8.95 | -0.56% | |
| 9.00 | 9.28 | 9.00 | 9.00 | -0.11% | |
| 8.79 | 9.12 | 8.79 | 9.01 | -0.44% | |
| 9.09 | 9.15 | 8.92 | 9.05 | -0.33% | |
| 9.16 | 9.30 | 9.08 | 9.08 | -1.20% | |
| 9.32 | 9.32 | 9.17 | 9.19 | -0.43% | |
| 9.21 | 9.23 | 9.07 | 9.23 | 0.00% | |
| 9.27 | 9.27 | 9.11 | 9.23 | -1.91% | |
| 9.44 | 9.48 | 9.12 | 9.41 | -0.95% | |
| 9.50 | 9.65 | 9.21 | 9.50 | +0.11% | |
| 9.07 | 9.90 | 9.07 | 9.49 | +3.49% | |
| 9.14 | 9.27 | 8.69 | 9.17 | +1.78% | |
| 9.05 | 9.28 | 8.90 | 9.01 | -0.44% | |
| 9.18 | 9.18 | 8.78 | 9.05 | -1.42% | |
| 9.01 | 9.19 | 9.01 | 9.18 | -0.22% | |
| 8.80 | 9.25 | 8.80 | 9.20 | +0.33% | |
| 9.40 | 9.40 | 8.88 | 9.17 | -1.08% | |
| 9.11 | 9.62 | 9.02 | 9.27 | +1.76% | |
| 9.21 | 9.21 | 8.98 | 9.11 | +0.22% | |
| 9.17 | 9.24 | 8.98 | 9.09 | +0.44% | |
| 9.16 | 9.38 | 9.00 | 9.05 | -0.66% | |
| 9.00 | 9.16 | 8.89 | 9.11 | +0.33% | |
| 8.96 | 9.31 | 8.82 | 9.08 | -0.22% | |
| 9.23 | 9.23 | 9.00 | 9.10 | -0.55% | |
| 9.03 | 9.17 | 8.81 | 9.15 | +0.66% | |
| 8.65 | 9.19 | 8.44 | 9.09 | +5.09% | |
| 8.48 | 8.65 | 8.33 | 8.65 | +4.09% | |
| 8.61 | 8.99 | 8.31 | 8.31 | -2.00% | |
| 8.88 | 8.88 | 8.40 | 8.48 | -2.53% | |
| 8.51 | 8.99 | 8.51 | 8.70 | +1.52% | |
| 8.95 | 9.04 | 8.51 | 8.57 | -3.49% | |
| 9.01 | 9.07 | 8.55 | 8.88 | -1.66% | |
| 9.02 | 9.14 | 8.96 | 9.03 | -0.99% | |
| 9.19 | 9.19 | 8.98 | 9.12 | +1.00% | |
| 9.10 | 9.17 | 8.90 | 9.03 | -2.27% | |
| 9.10 | 9.32 | 8.98 | 9.24 | +1.54% | |
| 9.20 | 9.20 | 9.00 | 9.10 | -1.09% | |
| 9.24 | 9.27 | 9.10 | 9.20 | -0.86% | |
| 9.14 | 9.44 | 9.05 | 9.28 | -0.32% | |
| 9.39 | 9.40 | 9.16 | 9.31 | -1.38% | |
| 9.14 | 9.53 | 8.91 | 9.44 | +3.17% | |
| 9.01 | 9.20 | 8.97 | 9.15 | -0.76% | |
| 9.45 | 9.60 | 9.05 | 9.22 | -3.76% | |
| 9.27 | 9.89 | 9.01 | 9.58 | +3.34% | |
| 8.90 | 9.54 | 8.89 | 9.27 | +2.43% | |
| 8.50 | 9.07 | 8.50 | 9.05 | +1.80% | |
| 9.00 | 9.02 | 8.75 | 8.89 | -1.33% | |
| 8.94 | 9.09 | 8.91 | 9.01 | +1.24% | |
| 9.00 | 9.30 | 8.90 | 8.90 | -0.45% | |
| 8.99 | 9.08 | 8.83 | 8.94 | +1.71% | |
| 8.69 | 9.22 | 7.82 | 8.79 | +0.46% | |
| 8.31 | 8.88 | 8.28 | 8.75 | +6.06% | |
| 8.50 | 8.50 | 8.06 | 8.25 | -1.08% | |
| 7.99 | 8.75 | 7.99 | 8.34 | +0.36% | |
| 8.00 | 8.32 | 7.90 | 8.31 | +4.01% | |
| 7.90 | 7.99 | 7.70 | 7.99 | +1.14% | |
| 7.80 | 7.99 | 7.80 | 7.90 | 0.00% | |
| 7.62 | 7.93 | 7.57 | 7.90 | +2.86% | |
| 7.80 | 8.33 | 7.60 | 7.68 | -0.26% | |
| 8.14 | 8.27 | 7.53 | 7.70 | -7.34% | |
| 8.20 | 8.31 | 8.08 | 8.31 | +2.03% | |
| 8.29 | 8.33 | 8.09 | 8.15 | -0.67% | |
| 8.34 | 8.51 | 8.20 | 8.20 | -0.61% | |
| 8.47 | 8.53 | 8.20 | 8.25 | -2.48% | |
| 8.47 | 8.50 | 8.09 | 8.46 | -0.70% | |
| 8.38 | 8.75 | 8.17 | 8.52 | +2.16% | |
| 8.47 | 8.47 | 8.29 | 8.34 | -0.12% | |
| 8.41 | 8.56 | 8.29 | 8.35 | +1.21% | |
| 8.40 | 8.60 | 8.17 | 8.25 | -3.79% | |
| 8.39 | 8.67 | 8.30 | 8.58 | +1.60% | |
| 8.04 | 8.44 | 7.97 | 8.44 | +3.18% | |
| 8.03 | 8.29 | 8.03 | 8.18 | +0.37% | |
| 8.19 | 8.80 | 8.05 | 8.15 | -2.51% | |
| 8.80 | 8.81 | 8.34 | 8.36 | -5.11% | |
| 7.74 | 9.00 | 7.74 | 8.81 | +13.53% | |
| 7.90 | 7.93 | 7.75 | 7.76 | +0.39% | |
| 7.73 | 7.92 | 7.69 | 7.73 | 0.00% | |
| 7.91 | 8.00 | 7.72 | 7.73 | -0.13% | |
| 7.75 | 7.91 | 7.60 | 7.74 | -0.90% | |
| 7.99 | 7.99 | 7.80 | 7.81 | -1.14% | |
| 7.70 | 8.05 | 7.70 | 7.90 | +2.46% | |
| 8.33 | 8.65 | 7.40 | 7.71 | -7.44% | |
| 8.30 | 8.66 | 8.30 | 8.33 | +0.12% | |
| 7.84 | 8.50 | 7.77 | 8.32 | +5.05% | |
| 7.74 | 8.07 | 7.65 | 7.92 | +1.67% | |
| 7.86 | 8.16 | 7.55 | 7.79 | -1.64% | |
| 8.25 | 8.27 | 7.88 | 7.92 | -3.18% | |
| 8.38 | 8.56 | 8.10 | 8.18 | -1.56% | |
| 8.46 | 8.46 | 8.07 | 8.31 | -1.89% | |
| 8.67 | 8.67 | 8.33 | 8.47 | -1.51% | |
| 8.63 | 8.63 | 8.40 | 8.60 | +0.94% | |
| 8.53 | 8.62 | 8.08 | 8.52 | +0.83% | |
| 8.62 | 8.63 | 8.27 | 8.45 | -1.40% | |
| 8.61 | 8.76 | 8.31 | 8.57 | +2.63% | |
| 8.19 | 8.77 | 8.19 | 8.35 | -0.60% | |
| 8.57 | 8.74 | 8.33 | 8.40 | -2.21% | |
| 8.67 | 8.67 | 8.32 | 8.59 | +1.54% | |
| 8.50 | 8.90 | 8.41 | 8.46 | -0.59% | |
| 8.52 | 8.81 | 8.47 | 8.51 | -0.58% | |
| 8.68 | 8.68 | 8.55 | 8.56 | -1.50% | |
| 8.99 | 8.99 | 8.46 | 8.69 | +2.24% | |
| 8.43 | 8.73 | 8.20 | 8.50 | +0.47% | |
| 8.50 | 9.20 | 8.44 | 8.46 | -0.59% | |
| 8.30 | 8.57 | 8.20 | 8.51 | +0.35% | |
| 8.54 | 8.80 | 8.46 | 8.48 | +0.83% | |
| 8.33 | 8.88 | 8.33 | 8.41 | +2.13% | |
| 8.48 | 8.51 | 8.02 | 8.24 | -1.02% | |
| 8.57 | 8.79 | 8.30 | 8.32 | -4.15% | |
| 8.62 | 9.25 | 8.41 | 8.68 | +1.76% | |
| 8.27 | 8.63 | 8.27 | 8.53 | +1.91% | |
| 7.80 | 8.65 | 7.80 | 8.37 | +6.49% | |
| 7.99 | 8.11 | 7.75 | 7.86 | 0.00% | |
| 7.25 | 7.99 | 7.16 | 7.86 | +7.82% | |
| 7.49 | 7.78 | 7.20 | 7.29 | -4.08% | |
| 7.38 | 7.90 | 7.38 | 7.60 | +2.29% | |
| 7.63 | 7.81 | 7.27 | 7.43 | -3.00% | |
| 7.06 | 8.09 | 6.68 | 7.66 | +7.28% | |
| 7.15 | 7.46 | 7.00 | 7.14 | -0.20% | |
| 7.14 | 7.46 | 6.47 | 7.15 | -5.37% | |
| 8.05 | 8.05 | 7.52 | 7.56 | -3.57% | |
| 7.63 | 7.92 | 7.50 | 7.84 | +3.70% | |
| 7.55 | 8.01 | 7.42 | 7.56 | +1.89% | |
| 7.56 | 7.70 | 7.38 | 7.42 | -2.03% | |
| 7.92 | 7.92 | 7.31 | 7.57 | -0.73% | |
| 7.38 | 7.84 | 7.24 | 7.63 | +3.22% | |
| 7.49 | 8.01 | 7.28 | 7.39 | -2.40% | |
| 7.32 | 7.90 | 7.18 | 7.57 | +2.46% | |
| 7.56 | 7.70 | 7.35 | 7.39 | -1.68% | |
| 7.62 | 7.83 | 7.42 | 7.52 | -1.29% | |
| 7.66 | 7.74 | 7.38 | 7.62 | -0.37% | |
| 7.49 | 8.18 | 7.42 | 7.64 | -0.91% | |
| 7.76 | 7.87 | 7.35 | 7.71 | -2.99% | |
| 8.19 | 8.19 | 7.70 | 7.95 | -0.35% | |
| 8.12 | 8.12 | 7.60 | 7.98 | -0.18% | |
| 7.85 | 8.26 | 7.62 | 7.99 | +2.51% | |
| 7.98 | 7.98 | 7.29 | 7.80 | -3.97% | |
| 8.12 | 8.44 | 7.80 | 8.12 | -2.68% | |
| 7.84 | 8.48 | 7.28 | 8.34 | +11.40% | |
| 7.52 | 7.57 | 7.04 | 7.49 | -1.29% | |
| 7.70 | 7.97 | 7.32 | 7.59 | -0.73% | |
| 7.48 | 7.74 | 7.32 | 7.64 | +0.92% | |
| 7.28 | 7.67 | 7.14 | 7.57 | +4.04% | |
| 7.53 | 7.56 | 7.14 | 7.28 | -4.76% | |
| 7.76 | 7.94 | 7.49 | 7.64 | -1.44% | |
| 8.06 | 8.12 | 7.43 | 7.76 | -5.78% | |
| 8.37 | 8.37 | 7.49 | 8.23 | -1.18% | |
| 8.40 | 8.46 | 8.06 | 8.33 | -2.46% | |
| 8.81 | 8.81 | 8.40 | 8.54 | -1.29% | |
| 8.61 | 8.74 | 8.55 | 8.65 | +0.49% | |
| 8.85 | 8.96 | 8.47 | 8.61 | -2.69% | |
| 8.90 | 8.90 | 8.51 | 8.85 | +0.48% | |
| 8.96 | 9.09 | 8.62 | 8.81 | +1.94% | |
| 8.40 | 8.82 | 8.02 | 8.64 | +3.35% | |
| 8.82 | 8.88 | 8.26 | 8.36 | -4.63% | |
| 8.86 | 8.86 | 8.54 | 8.76 | -2.19% | |
| 9.10 | 9.10 | 8.88 | 8.96 | 0.00% | |
| 9.17 | 9.17 | 8.82 | 8.96 | -0.93% | |
| 9.18 | 9.32 | 8.97 | 9.04 | -1.52% | |
| 9.24 | 9.62 | 9.10 | 9.18 | -1.65% | |
| 9.93 | 9.93 | 9.24 | 9.34 | -1.91% | |
| 10.36 | 10.36 | 9.52 | 9.52 | -6.08% | |
| 9.95 | 10.42 | 9.94 | 10.14 | +2.70% | |
| 9.80 | 10.07 | 9.80 | 9.87 | +1.44% | |
| 9.46 | 10.02 | 9.45 | 9.73 | +2.81% | |
| 9.48 | 9.66 | 9.18 | 9.46 | +0.60% | |
| 9.10 | 9.59 | 8.96 | 9.41 | +5.00% | |
| 8.85 | 9.20 | 8.85 | 8.96 | -1.54% | |
| 9.24 | 9.24 | 8.85 | 9.10 | 0.00% | |
| 9.14 | 9.27 | 9.03 | 9.10 | -1.81% | |
| 9.44 | 9.45 | 9.17 | 9.27 | -0.45% | |
| 9.27 | 9.44 | 9.27 | 9.31 | +0.45% | |
| 9.27 | 9.38 | 9.10 | 9.27 | 0.00% | |
| 9.42 | 9.53 | 9.13 | 9.27 | -1.05% | |
| 9.10 | 9.51 | 9.10 | 9.37 | +2.92% | |
| 9.11 | 9.31 | 8.82 | 9.10 | 0.00% | |
| 9.11 | 9.30 | 8.92 | 9.10 | 0.00% | |
| 9.14 | 9.46 | 8.95 | 9.10 | 0.00% | |
| 9.66 | 9.77 | 8.93 | 9.10 | -4.55% | |
| 9.95 | 10.15 | 9.39 | 9.53 | -4.08% | |
| 10.11 | 10.28 | 9.94 | 9.94 | -1.11% | |
| 10.22 | 10.25 | 9.95 | 10.05 | -1.91% | |
| 10.19 | 10.36 | 9.88 | 10.25 | +0.27% | |
| 9.73 | 10.26 | 9.52 | 10.22 | 0.00% | |
| 10.21 | 10.32 | 9.66 | 10.22 | -1.48% | |
| 10.09 | 10.49 | 9.80 | 10.37 | +4.96% | |
| 9.81 | 10.36 | 9.66 | 9.88 | -0.14% | |
| 10.08 | 10.33 | 9.80 | 9.90 | -4.46% | |
| 10.43 | 10.60 | 10.28 | 10.36 | -2.37% | |
| 10.61 | 10.65 | 10.47 | 10.61 | +1.07% | |
| 10.61 | 10.71 | 10.50 | 10.50 | -0.66% | |
| 10.50 | 10.71 | 10.44 | 10.57 | +0.40% | |
| 10.54 | 10.68 | 10.36 | 10.53 | -0.13% | |
| 10.50 | 10.63 | 10.35 | 10.54 | +0.40% | |
| 11.20 | 11.20 | 10.22 | 10.50 | -7.06% | |
| 10.50 | 11.30 | 10.40 | 11.30 | +7.60% | |
| 10.04 | 10.60 | 9.90 | 10.50 | +3.59% | |
| 9.90 | 10.25 | 9.53 | 10.14 | +2.40% | |
| 9.24 | 10.14 | 9.24 | 9.90 | +0.71% | |
| 10.43 | 10.44 | 9.11 | 9.83 | -9.18% | |
| 10.81 | 11.12 | 10.46 | 10.82 | -2.64% | |
| 11.13 | 11.20 | 10.33 | 11.12 | -1.37% | |
| 11.62 | 11.75 | 10.58 | 11.27 | -0.25% | |
| 11.90 | 11.90 | 10.82 | 11.30 | -3.00% | |
| 11.23 | 11.87 | 10.98 | 11.65 | +2.09% | |
| 11.20 | 11.68 | 11.20 | 11.41 | +1.62% | |
| 11.90 | 12.01 | 11.10 | 11.23 | -5.65% | |
| 11.20 | 12.32 | 11.20 | 11.90 | +6.65% | |
| 11.59 | 11.59 | 10.79 | 11.16 | -0.87% | |
| 11.55 | 12.59 | 10.84 | 11.26 | -0.74% | |
| 11.41 | 11.55 | 10.98 | 11.34 | -1.22% | |
| 11.72 | 11.86 | 11.35 | 11.48 | -1.32% | |
| 11.40 | 11.79 | 11.06 | 11.63 | +5.19% | |
| 10.98 | 11.20 | 10.81 | 11.06 | +2.20% | |
| 10.50 | 10.99 | 10.15 | 10.82 | +2.66% | |
| 10.50 | 11.90 | 10.35 | 10.54 | -0.26% | |
| 11.12 | 11.12 | 10.50 | 10.57 | +0.13% | |
| 10.92 | 11.13 | 10.51 | 10.56 | +1.48% | |
| 10.50 | 10.92 | 10.35 | 10.40 | -1.98% | |
| 11.27 | 11.27 | 10.51 | 10.61 | -4.05% | |
| 10.57 | 11.20 | 10.39 | 11.06 | +4.08% | |
| 10.78 | 10.95 | 10.50 | 10.63 | -2.19% | |
| 11.17 | 11.48 | 10.85 | 10.86 | -2.27% | |
| 12.04 | 12.04 | 11.00 | 11.12 | -5.25% | |
| 12.17 | 12.17 | 11.51 | 11.73 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the XLO chart for longer ranges.