AEON Biopharma (AEON) vs Karyopharm Therapeutics (KPTI)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
AEON Biopharma (AEON) has outperformed Karyopharm Therapeutics (KPTI) over the past year, losing 66.3% versus a loss of 89.8%. AEON Biopharma is the larger company by market cap ($15.5 million vs $13.6 million), about 1.1 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | AEON | KPTI |
|---|---|---|
| Share price | $0.31 | $0.60 |
| Market cap | $15.46M | $13.61M |
| 1-day change | -0.40% | -6.98% |
| YTD return | -71.82% | -91.85% |
| 1-year return | -66.30% | -89.83% |
| 5-year return | — | -99.28% |
| EPS (TTM) | $-4.39 | $-14.33 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $1.45 | $10.99 |
| 52-week low | $0.177 | $0.60 |
| Distance from 52-week high | -78.62% | -94.54% |
| Analyst consensus | strong_buy | none |
| Avg. price target upside | +487.10% | +1108.33% |
| Average volume | 8.59M | 1.71M |
| Shares outstanding | 49.88M | 22.68M |
| Employees | 8 | 228 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- AEON has outperformed KPTI by 23.5 percentage points over the past year.
About AEON Biopharma
AEON stock →AEON Biopharma, Inc., a clinical stage biopharmaceutical company, focuses on developing botulinum toxins. It develops ABP-450 (prabotulinumtoxinA) injection for debilitating medical conditions, which completed Phase 2 study for the treatment of cervical dystonia and has an ongoing Phase 2 study for the treatment of chronic and episodic migraine.
Health Care · Biotechnology: Pharmaceutical Preparations · 8 employees
About Karyopharm Therapeutics
KPTI stock →Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States. The company discovers, develops, and commercializes novel and small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1).
Health Care · Biotechnology: Pharmaceutical Preparations · 228 employees
AEON vs KPTI FAQ
Which is bigger, AEON Biopharma or Karyopharm Therapeutics?
AEON Biopharma (AEON) is larger, with a market capitalization of $15.46M compared with $13.61M for Karyopharm Therapeutics (KPTI).
Which stock has performed better over the past year, AEON or KPTI?
AEON returned -66.30% over the past 12 months, compared with -89.83% for KPTI (price return, excluding dividends). Past performance does not predict future results.
Are AEON Biopharma and Karyopharm Therapeutics in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.