Karyopharm Therapeutics Inc. (KPTI)
NASDAQ: KPTIHealth CareBiotechnology: Pharmaceutical PreparationsUSD
Market open · Delayed 15 min · as of Oct 8, 2:13 PM ET
KPTI stock chart
Technical analysisKey statistics
All statistics- Market cap
- $13.98M
- EPS (TTM)
- -$14.33
- Dividend yield
- None
- 52-week range
- 0.60 – 10.99
- Day range
- 0.60 – 0.6438
- Volume / Avg
- 473.36K / 1.70M
- Beta
- —
- Shares outstanding
- 22.68M
- Next earnings
- Nov 2, 2026
52-week range
KPTI stock today
Shares of Karyopharm Therapeutics (KPTI) are trading lower on Oct 8 at $0.6163, a drop of 4.44% or $0.0287 per share, versus the S&P 500's 0.65% decline. At this level, KPTI sits near the bottom of its 52-week range of $0.60 to $10.99: 94.4% below the high, set on Feb 24, 2026 and 2.7% above the low. KPTI is down 91.2% year to date, underperforming the S&P 500 (+14.0%). Over the past 12 months, the stock has lost 88.8%.
Karyopharm Therapeutics has posted a net loss over the last twelve months (EPS of -$14.33), so its P/E ratio is not meaningful. Karyopharm Therapeutics's next earnings report is expected on Nov 2, 2026.
Summary generated from market data by MetaCap's automated system. Methodology
About Karyopharm Therapeutics
Company profile- Sector
- Health Care
- Industry
- Biotechnology: Pharmaceutical Preparations
- IPO year
- 2013
Earnings
Earnings history- Next report
- Nov 2, 2026
- EPS estimate
- $-1.15
Karyopharm Therapeutics peers
Health Care sector| Company | Price | % Chg | Market cap | Compare |
|---|---|---|---|---|
| DAREDare Bioscience Inc. | 0.7556 | -4.36% | $14.86M | vs KPTI |
| KTTAPasithea Therapeutics Corp. | 0.4507 | +1.65% | $15.06M | vs KPTI |
| TVRDTvardi Therapeutics Inc. | 1.07 | -2.73% | $14.27M | vs KPTI |
| ALLRAllarity Therapeutics Inc. | 0.9706 | -1.35% | $15.44M | vs KPTI |
| HINDVyome Holdings Inc. | 1.99 | -2.45% | $13.97M | vs KPTI |
| ACTUActuate Therapeutics Inc. | 0.6601 | -8.85% | $15.85M | vs KPTI |
| AEONAEON Biopharma Inc. Class A | 0.3178 | +2.10% | $15.85M | vs KPTI |
| BFRIBiofrontera Inc. | 0.915 | -2.21% | $13.59M | vs KPTI |
Indexes, lists and sector
Karyopharm Therapeutics stock FAQ
What is Karyopharm Therapeutics's stock price today?
KPTI last traded at $0.6163 as of Oct 8, 2:13 PM EDT, down 4.44% on the day. Prices are delayed at least 15 minutes.
Does Karyopharm Therapeutics pay a dividend?
No. Karyopharm Therapeutics does not currently pay a regular cash dividend.
When is Karyopharm Therapeutics's next earnings date?
Karyopharm Therapeutics is expected to report earnings on Monday, November 2, 2026. Analysts expect EPS of $-1.15.
Has KPTI ever split its stock?
Yes. The most recent KPTI stock split was a 1-for-15 split on Feb 26, 2025.
What is the KPTI 52-week high?
The 52-week high for KPTI is $10.99 and the 52-week low is $0.60. The stock is currently 94.4% below its high.