MetaCap

Annexon (ANNX) vs Obsidian Therapeutics (OBX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Obsidian Therapeutics is the larger company by market cap ($770.3 million vs $757.4 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ANNX-21.83%OBX-24.57%
+106%+35%-35%
Jul 27, 20261 yearOct 7, 2026
ANNX-21.30%OBX-15.49%
+81%+24%-34%
Jul 27, 20265 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ANNX versus OBX key metrics
MetricANNXOBX
Share price$4.00$12.47
Market cap$757.37M$770.31M
1-day change-0.37%-5.53%
YTD return-20.12%—
1-year return+30.62%—
5-year return-81.77%—
EPS (TTM)$-1.13$-1.63
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$7.18$49.97
52-week low$2.54$12.16
Distance from 52-week high-44.36%-75.05%
Analyst consensusbuystrong_buy
Avg. price target upside+286.23%+212.75%
Average volume3.11M364.47K
Shares outstanding189.58M61.77M
Employees9287
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Annexon

ANNX stock →

Annexon, Inc., a clinical-stage biopharmaceutical company, discovers and develops medicines for treating inflammatory-related diseases. The company provides Tanruprubart, an investigational full-length monoclonal antibody, which is in Phase 3 clinical trial for the treatment of patients with guillain-barré syndrome; completed Phase II clinical trial for treating Huntington's disease; and in Phase 2a clinical trial for the treatment of amyotrophic lateral sclerosis.

Health Care · Biotechnology: Pharmaceutical Preparations · 92 employees

About Obsidian Therapeutics

OBX stock →

Obsidian Therapeutics, Inc. operates as a clinical-stage biotechnology company developing engineered cell and gene therapies.

Health Care · Biotechnology: Pharmaceutical Preparations · 87 employees

ANNX vs OBX FAQ

Which is bigger, Annexon or Obsidian Therapeutics?

Obsidian Therapeutics (OBX) is larger, with a market capitalization of $770.31M compared with $757.37M for Annexon (ANNX).

Are Annexon and Obsidian Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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