Collegium Pharmaceutical (COLL) vs Cronos Group (CRON)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Cronos Group (CRON) has outperformed Collegium Pharmaceutical (COLL) over the past year, gaining 23.7% versus a loss of 34.3%. Over five years, COLL leads with a +4.5% price change compared with -40.9% for CRON. Cronos Group is the larger company by market cap ($1.19 billion vs $713.9 million), about 1.7 times the size.
On valuation, Cronos Group trades at a lower trailing P/E (17.1x vs 17.3x for Collegium Pharmaceutical).
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | COLL | CRON |
|---|---|---|
| Share price | $21.93 | $3.24 |
| Market cap | $713.94M | $1.19B |
| 1-day change | +0.23% | -1.37% |
| YTD return | -52.63% | +23.19% |
| 1-year return | -34.32% | +23.66% |
| 5-year return | +4.53% | -40.88% |
| P/E ratio (TTM) | 17.27 | 17.05 |
| Forward P/E | 3.30 | — |
| EPS (TTM) | $1.27 | $0.19 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $50.79 | $3.61 |
| 52-week low | $21.43 | $2.28 |
| Distance from 52-week high | -56.82% | -10.20% |
| Analyst consensus | strong_buy | strong_buy |
| Avg. price target upside | +123.44% | -24.07% |
| Average volume | 748.29K | 1.13M |
| Shares outstanding | 32.56M | 368.41M |
| Employees | 423 | 610 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Medicinal Chemicals and Botanical Products |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- CRON has outperformed COLL by 58.0 percentage points over the past year.
About Collegium Pharmaceutical
COLL stock →Collegium Pharmaceutical, Inc., a specialty pharmaceutical company, engages in the development and commercialization of medicines for pain management. The company's portfolio includes Jornay PM, a central nervous system stimulant prescription medicine that contains methylphenidate HCl for the treatment of attention deficit hyperactivity disorder; Belbuca, a buccal film that contains buprenorphine for severe and persistent pain that requires an extended treatment period; Xtampza ER, an abuse-deterrent, extended-release, oral formulation of oxycodone for the management of pain severe enough to require daily; Nucynta ER and Nucynta IR, which are extended-release and immediate-release oral formulations of tapentadol, indicated for the management of acute, severe, and persistent pain; and Symproic, an oral formulation of naldemedine for the treatment of opioid-induced constipation in adult patients with chronic non-cancer pain.
Health Care · Biotechnology: Pharmaceutical Preparations · 423 employees
About Cronos Group
CRON stock →Cronos Group Inc., a cannabinoid company, engages in the cultivation, production, distribution, and marketing of cannabis products in Canada, Israel, and internationally. It offers dried flowers, pre-rolls, oils, vaporizers, edibles, and tinctures under the Spinach, Lord Jones, Lit, and Peace Naturals brand names.
Health Care · Medicinal Chemicals and Botanical Products · 610 employees
COLL vs CRON FAQ
Which is bigger, Collegium Pharmaceutical or Cronos Group?
Cronos Group (CRON) is larger, with a market capitalization of $1.19B compared with $713.94M for Collegium Pharmaceutical (COLL).
Which stock has performed better over the past year, COLL or CRON?
CRON returned +23.66% over the past 12 months, compared with -34.32% for COLL (price return, excluding dividends). Past performance does not predict future results.
Which has the lower P/E ratio, COLL or CRON?
CRON has the lower trailing P/E at 17.1, versus 17.3 for COLL. A lower P/E is not by itself a sign of a better investment; it can reflect slower expected growth or higher risk.
Are Collegium Pharmaceutical and Cronos Group in the same industry?
Both are in the Health Care sector, but in different industries: Biotechnology: Pharmaceutical Preparations for Collegium Pharmaceutical and Medicinal Chemicals and Botanical Products for Cronos Group.