Caribou Biosciences (CRBU) vs Hyperion DeFi (HYPD)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Hyperion DeFi (HYPD) has outperformed Caribou Biosciences (CRBU) over the past year, losing 62.9% versus a loss of 82.0%. Over five years, CRBU leads with a -97.7% price change compared with -99.2% for HYPD. Caribou Biosciences is the larger company by market cap ($51.6 million vs $51.2 million), about 1.0 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | CRBU | HYPD |
|---|---|---|
| Share price | $0.4812 | $3.37 |
| Market cap | $51.59M | $51.16M |
| 1-day change | -22.06% | -6.27% |
| YTD return | -69.74% | -5.48% |
| 1-year return | -82.04% | -62.86% |
| 5-year return | -97.69% | -99.21% |
| EPS (TTM) | $-1.08 | $-6.46 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $3.54 | $9.50 |
| 52-week low | $0.45 | $2.34 |
| Distance from 52-week high | -86.39% | -64.58% |
| Analyst consensus | buy | none |
| Avg. price target upside | +1094.93% | +192.12% |
| Average volume | 2.14M | 445.34K |
| Shares outstanding | 107.21M | 15.20M |
| Employees | 97 | 9 |
| Sector | Healthcare | Healthcare |
| Industry | Biotechnology | Biotechnology |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- HYPD has outperformed CRBU by 19.2 percentage points over the past year.
About Caribou Biosciences
CRBU stock →Caribou Biosciences, Inc. operates as a clinical-stage clustered regularly interspaced short palindromic repeats (CRISPR) genome-editing biopharmaceutical company.
Healthcare · Biotechnology · 97 employees
About Hyperion DeFi
HYPD stock →Hyperion DeFi, Inc., a DeFi company, engages in building on Hyperliquid. It operates through two segments: Ophthalmic Technology and Digital Assets.
Healthcare · Biotechnology · 9 employees
CRBU vs HYPD FAQ
Which is bigger, Caribou Biosciences or Hyperion DeFi?
Caribou Biosciences (CRBU) is larger, with a market capitalization of $51.59M compared with $51.16M for Hyperion DeFi (HYPD).
Which stock has performed better over the past year, CRBU or HYPD?
HYPD returned -62.86% over the past 12 months, compared with -82.04% for CRBU (price return, excluding dividends). Past performance does not predict future results.
Are Caribou Biosciences and Hyperion DeFi in the same industry?
Yes. Both are classified in the Biotechnology industry within the Healthcare sector.