Annovis Bio (ANVS) vs Hyperion DeFi (HYPD)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Annovis Bio (ANVS) has outperformed Hyperion DeFi (HYPD) over the past year, losing 46.5% versus a loss of 61.6%. Over five years, ANVS leads with a -95.7% price change compared with -99.2% for HYPD. Hyperion DeFi is the larger company by market cap ($54.6 million vs $51.6 million), about 1.1 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | ANVS | HYPD |
|---|---|---|
| Share price | $1.21 | $3.59 |
| Market cap | $51.64M | $54.58M |
| 1-day change | +2.54% | -6.02% |
| YTD return | -65.03% | +0.84% |
| 1-year return | -46.46% | -61.60% |
| 5-year return | -95.68% | -99.15% |
| EPS (TTM) | $-1.75 | $-6.46 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $5.50 | $9.50 |
| 52-week low | $1.04 | $2.34 |
| Distance from 52-week high | -78.00% | -62.21% |
| Average volume | 895.73K | 444.51K |
| Shares outstanding | 42.68M | 15.20M |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- ANVS has outperformed HYPD by 15.1 percentage points over the past year.
ANVS vs HYPD FAQ
Which is bigger, Annovis Bio or Hyperion DeFi?
Hyperion DeFi (HYPD) is larger, with a market capitalization of $54.58M compared with $51.64M for Annovis Bio (ANVS).
Which stock has performed better over the past year, ANVS or HYPD?
ANVS returned -46.46% over the past 12 months, compared with -61.60% for HYPD (price return, excluding dividends). Past performance does not predict future results.
Are Annovis Bio and Hyperion DeFi in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.