Definitive Healthcare (DH) vs OptimizeRx (OPRX)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
OptimizeRx (OPRX) has outperformed Definitive Healthcare (DH) over the past year, losing 54.1% versus a loss of 69.6%. Over five years, OPRX leads with a -90.1% price change compared with -97.7% for DH. OptimizeRx is the larger company by market cap ($157.8 million vs $103.1 million), about 1.5 times the size.
On valuation, Definitive Healthcare trades at a lower forward P/E (5.2x vs 8.0x for OptimizeRx).
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | DH | OPRX |
|---|---|---|
| Share price | $0.9663 | $8.38 |
| Market cap | $103.15M | $157.85M |
| 1-day change | -0.41% | -1.99% |
| YTD return | -66.19% | -31.65% |
| 1-year return | -69.58% | -54.06% |
| 5-year return | -97.71% | -90.10% |
| P/E ratio (TTM) | — | 34.92 |
| Forward P/E | 5.18 | 8.03 |
| EPS (TTM) | $-1.61 | $0.24 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $3.15 | $22.25 |
| 52-week low | $0.61 | $4.54 |
| Distance from 52-week high | -69.31% | -62.34% |
| Analyst consensus | none | strong_buy |
| Avg. price target upside | +96.63% | +50.36% |
| Average volume | 586.27K | 203.38K |
| Shares outstanding | 106.74M | 18.84M |
| Employees | 678 | 132 |
| Sector | Healthcare | Healthcare |
| Industry | Health Information Services | Health Information Services |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- OPRX has outperformed DH by 15.5 percentage points over the past year.
About Definitive Healthcare
DH stock →Definitive Healthcare Corp., together with its subsidiaries, provides software as a service (SaaS) healthcare commercial intelligence platform in the United States and internationally. Its SaaS platform provides information on healthcare providers and their activities to help its customers from product development to go-to-market planning, and sales and marketing execution.
Healthcare · Health Information Services · 678 employees
About OptimizeRx
OPRX stock →OptimizeRx Corporation operates as a digital healthcare technology company. It offers Dynamic Audience Activation Platform, which generates dynamic audiences with predictive analytics through machine learning methods; Micro-Neighborhood Targeting, which creates consumer audiences using a privacy-first process; Profiler, which provides insights into its customers' target consumers; banner messages, including brand messaging, therapeutic support messaging, affordability messaging, limited distribution drug information, and patient support program messaging through healthcare professionals; and media execution solutions, which deliver messages through consumer omnichannel network, including through programmatic display, programmatic connected television/over-the-top, programmatic social media, addressable television, digital out-of-home, programmatic audio, and email/direct mail.
Healthcare · Health Information Services · 132 employees
DH vs OPRX FAQ
Which is bigger, Definitive Healthcare or OptimizeRx?
OptimizeRx (OPRX) is larger, with a market capitalization of $157.85M compared with $103.15M for Definitive Healthcare (DH).
Which stock has performed better over the past year, DH or OPRX?
OPRX returned -54.06% over the past 12 months, compared with -69.58% for DH (price return, excluding dividends). Past performance does not predict future results.
Are Definitive Healthcare and OptimizeRx in the same industry?
Yes. Both are classified in the Health Information Services industry within the Healthcare sector.