Helus Pharma (HELP) vs Rigel Pharmaceuticals (RIGL)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 10, 2026.
Summary
Helus Pharma (HELP) has outperformed Rigel Pharmaceuticals (RIGL) over the past year, gaining 88.2% versus a gain of 72.8%. Over five years, RIGL leads with a +45.2% price change compared with -84.2% for HELP. Rigel Pharmaceuticals is the larger company by market cap ($916.8 million vs $862.1 million), about 1.1 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | HELP | RIGL |
|---|---|---|
| Share price | $11.80 | $49.08 |
| Market cap | $862.11M | $916.81M |
| 1-day change | +10.07% | +0.74% |
| YTD return | +44.25% | +14.59% |
| 1-year return | +88.20% | +72.82% |
| 5-year return | -84.24% | +45.21% |
| P/E ratio (TTM) | — | 2.91 |
| Forward P/E | — | 9.94 |
| EPS (TTM) | $-4.15 | $16.88 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | — | $294.28M |
| Revenue growth (YoY) | — | +64.15% |
| Net income (latest FY) | — | $367.02M |
| Gross margin | — | 93.33% |
| Operating margin | — | 42.63% |
| Net margin | — | 124.72% |
| 52-week high | $15.15 | $52.24 |
| 52-week low | $3.76 | $24.95 |
| Distance from 52-week high | -22.11% | -6.05% |
| Analyst consensus | strong_buy | none |
| Avg. price target upside | +237.54% | +28.36% |
| Average volume | 1.77M | 286.19K |
| Shares outstanding | 73.06M | 18.68M |
| Employees | 100 | 172 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- HELP has outperformed RIGL by 15.4 percentage points over the past year.
About Helus Pharma
HELP stock →Helus Pharma Inc., doing business as Helus Pharma, operates as a clinical stage pharmaceutical company that focuses on developing therapies to treat psychiatric and neurological conditions. It develops HLP003, a deuterated psilocybin analog, which is in phase 3 clinical trial to treat major depressive disorder; and HLP004, a deuterated N, N-dimethyltryptamine, which is in phase 2 clinical trial for treating generalized anxiety disorders.
Health Care · Biotechnology: Pharmaceutical Preparations · 100 employees
About Rigel Pharmaceuticals
RIGL stock →Rigel Pharmaceuticals, Inc., a biotechnology company, develops and provides therapies that enhance the lives of patients with hematologic disorders and cancer in the United States. The company offers TAVALISSE, an oral spleen tyrosine kinase inhibitor for the treatment of adult patients with chronic immune thrombocytopenia; REZLIDHIA, a non-intensive monotherapy to treat adult patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) with a susceptible isocitrate dehydrogenase-1 (IDH1) mutation as detected by an FDA-approved test; and GAVRETO, a once daily, small molecule, oral, kinase inhibitor for the treatment of adult patients with metastatic rearranged during transfection (RET) fusion-positive non-small cell lung cancer (NSCLC), as well as to treat adult and pediatric patients twelve years of age and older with advanced or metastatic RET fusion-positive thyroid cancer.
Health Care · Biotechnology: Pharmaceutical Preparations · 172 employees
HELP vs RIGL FAQ
Which is bigger, Helus Pharma or Rigel Pharmaceuticals?
Rigel Pharmaceuticals (RIGL) is larger, with a market capitalization of $916.81M compared with $862.11M for Helus Pharma (HELP).
Which stock has performed better over the past year, HELP or RIGL?
HELP returned +88.20% over the past 12 months, compared with +72.82% for RIGL (price return, excluding dividends). Past performance does not predict future results.
Are Helus Pharma and Rigel Pharmaceuticals in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.