OPKO Health (OPK) vs Exagen (XGN)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
OPKO Health (OPK) has outperformed Exagen (XGN) over the past year, losing 9.7% versus a loss of 24.3%. Over five years, XGN leads with a -34.3% price change compared with -62.6% for OPK. OPKO Health is the larger company by market cap ($1.02 billion vs $197.9 million), about 5.2 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | OPK | XGN |
|---|---|---|
| Share price | $1.37 | $8.17 |
| Market cap | $1.02B | $197.92M |
| 1-day change | -1.44% | -1.57% |
| YTD return | +10.32% | +36.51% |
| 1-year return | -9.74% | -24.27% |
| 5-year return | -62.63% | -34.28% |
| EPS (TTM) | $-0.09 | $-0.81 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $1.75 | $12.23 |
| 52-week low | $0.98 | $2.59 |
| Distance from 52-week high | -21.71% | -33.20% |
| Analyst consensus | none | none |
| Avg. price target upside | +219.71% | +24.11% |
| Average volume | 3.35M | 328.42K |
| Shares outstanding | 746.33M | 24.23M |
| Employees | 2,275 | 216 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Medical Specialities |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- OPKO Health is about 5.2 times larger than Exagen by market value ($1.02B vs $197.92M).
- OPK has outperformed XGN by 14.5 percentage points over the past year.
About OPKO Health
OPK stock →OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally.
Health Care · Biotechnology: Pharmaceutical Preparations · 2,275 employees
About Exagen
XGN stock →Exagen Inc. designs, develops, and commercializes various testing products under the AVISE brand in the United States.
Health Care · Medical Specialities · 216 employees
OPK vs XGN FAQ
Which is bigger, OPKO Health or Exagen?
OPKO Health (OPK) is larger, with a market capitalization of $1.02B compared with $197.92M for Exagen (XGN).
Which stock has performed better over the past year, OPK or XGN?
OPK returned -9.74% over the past 12 months, compared with -24.27% for XGN (price return, excluding dividends). Past performance does not predict future results.
Are OPKO Health and Exagen in the same industry?
Both are in the Health Care sector, but in different industries: Biotechnology: Pharmaceutical Preparations for OPKO Health and Medical Specialities for Exagen.