MetaCap

Scribe Therapeutics (SCTX) vs Upstream Bio (UPB)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Scribe Therapeutics is the larger company by market cap ($400.8 million vs $257.4 million), about 1.6 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

SCTX+1.37%UPB-28.91%
+103%+34%-35%
Jul 27, 20261 yearOct 8, 2026
SCTX-1.28%UPB-27.89%
+80%+24%-33%
Jul 27, 20265 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

SCTX versus UPB key metrics
MetricSCTXUPB
Share price$21.17$4.70
Market cap$400.78M$257.42M
1-day change+10.09%+3.30%
YTD return—-83.24%
1-year return—-75.95%
EPS (TTM)$-3.84$-2.88
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$39.60$33.68
52-week low$13.50$4.37
Distance from 52-week high-46.54%-86.05%
Analyst consensusnonenone
Avg. price target upside+169.25%+562.55%
Average volume357.40K647.42K
Shares outstanding18.93M54.77M
Employees8275
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Scribe Therapeutics

SCTX stock →

Scribe Therapeutics Inc. operates as a clinical-stage biotechnology company, focuses on research and developing genetic medicines using CRISPR-based tools to address the root cause of diseases, with a primary focus on cardiometabolic conditions in the United States.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 82 employees

About Upstream Bio

UPB stock →

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. It offers verekitug, which is in Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease and in Phase I clinical trial for treating chronic obstructive pulmonary disease.

Health Care · Biotechnology: Pharmaceutical Preparations · 75 employees

SCTX vs UPB FAQ

Which is bigger, Scribe Therapeutics or Upstream Bio?

Scribe Therapeutics (SCTX) is larger, with a market capitalization of $400.78M compared with $257.42M for Upstream Bio (UPB).

Are Scribe Therapeutics and Upstream Bio in the same industry?

Both are in the Health Care sector, but in different industries: Biotechnology: Biological Products (No Diagnostic Substances) for Scribe Therapeutics and Biotechnology: Pharmaceutical Preparations for Upstream Bio.

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