MetaCap

SCYNEXIS (SCYX) vs TherapeuticsMD (TXMD)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

TherapeuticsMD (TXMD) has outperformed SCYNEXIS (SCYX) over the past year, gaining 89.6% versus a loss of 32.1%. Over five years, SCYX leads with a -90.5% price change compared with -94.4% for TXMD. SCYNEXIS is the larger company by market cap ($42.0 million vs $23.3 million), about 1.8 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

SCYX-32.11%TXMD+89.62%
+172%+59%-53%
Oct 8, 20251 yearOct 8, 2026
SCYX-89.74%TXMD-94.17%
+52%-27%-105%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

SCYX versus TXMD key metrics
MetricSCYXTXMD
Share price$4.22$2.01
Market cap$41.99M$23.26M
1-day change-11.72%+0.50%
YTD return-16.53%+23.31%
1-year return-32.11%+89.62%
5-year return-90.53%-94.42%
Forward P/E—5.74
EPS (TTM)$-0.89$-0.04
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$9.12$2.95
52-week low$3.53$1.03
Distance from 52-week high-53.73%-31.86%
Analyst consensusstrong_buy—
Avg. price target upside+760.90%—
Average volume274.80K23.94K
Shares outstanding9.95M11.57M
Employees181
SectorHealthcareHealthcare
IndustryDrug Manufacturers - Specialty & GenericDrug Manufacturers - Specialty & Generic

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • TXMD has outperformed SCYX by 121.7 percentage points over the past year.

About SCYNEXIS

SCYX stock →

SCYNEXIS, Inc., a biotechnology company, engages in drug development for the treatment and prevention of difficult-to-treat and drug-resistant fungal infections in the United States. The company offers BREXAFEMME for the treatment of patients with vulvovaginal candidiasis and for the reduction in the incidence of recurrence.

Healthcare · Drug Manufacturers - Specialty & Generic · 18 employees

About TherapeuticsMD

TXMD stock →

TherapeuticsMD, Inc. operates as a pharmaceutical royalty company in the United States and internationally.

Healthcare · Drug Manufacturers - Specialty & Generic · 1 employees

SCYX vs TXMD FAQ

Which is bigger, SCYNEXIS or TherapeuticsMD?

SCYNEXIS (SCYX) is larger, with a market capitalization of $41.99M compared with $23.26M for TherapeuticsMD (TXMD).

Which stock has performed better over the past year, SCYX or TXMD?

TXMD returned +89.62% over the past 12 months, compared with -32.11% for SCYX (price return, excluding dividends). Past performance does not predict future results.

Are SCYNEXIS and TherapeuticsMD in the same industry?

Yes. Both are classified in the Drug Manufacturers - Specialty & Generic industry within the Healthcare sector.

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