Alnylam Pharmaceuticals Stock Price History
NASDAQ: ALNYHealth CareBiotechnology: Pharmaceutical PreparationsUSD
232.68+8.15 (+3.63%)
At close: Oct 9, 4:00 PM ET · Delayed 15 min
ALNY price history at a glance
The price history for Alnylam Pharmaceuticals (ALNY) on this page begins on May 31, 2004, when the stock closed at $7.68; it most recently closed at $232.68 on October 5, 2026. The highest price in this record is $495.55, reached on October 20, 2025; the latest close is 53.0% below that peak. Across the 21 complete calendar years in the table, ALNY finished higher in 13 and lower in 8. Its best year was 2017 (+239.3%) and its worst was 2016 (-60.2%).
Over roughly 22 years the share price changed +2929.7%, a 16.5% compound annual price return (excluding dividends). In the last 12 months alone, ALNY has lost 49.5%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2004
- $495.55
- Date of high
- Oct 20, 2025
- Low since 2004
- $3.65
- Date of low
- Aug 16, 2004
- 52-week high
- $495.55
- 52-week low
- $197.81
- IPO year
- 2004
- Last close
- $232.68
ALNY returns
1 week
+5.90%
1 month
-9.81%
3 months
-22.12%
6 months
-27.76%
Year to date
-41.49%
1 year
-49.47%
3 years
+38.40%
5 years
+11.57%
ALNY price return, excluding dividends.
ALNY annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 232.68 | -41.85% |
| 2025 | 400.17 | +70.81% |
| 2024 | 234.28 | +22.40% |
| 2023 | 191.41 | -19.46% |
| 2022 | 237.65 | +40.14% |
| 2021 | 169.58 | +30.48% |
| 2020 | 129.97 | +12.35% |
| 2019 | 115.68 | +53.83% |
| 2018 | 75.20 | -40.81% |
| 2017 | 127.05 | +239.34% |
| 2016 | 37.44 | -60.23% |
| 2015 | 94.14 | -3.71% |
| 2014 | 97.77 | +54.85% |
| 2013 | 63.14 | +231.62% |
| 2012 | 19.04 | +133.62% |
| 2011 | 8.15 | -17.34% |
| 2010 | 9.86 | -44.04% |
| 2009 | 17.62 | -29.94% |
| 2008 | 25.15 | -13.28% |
| 2007 | 29.00 | +35.51% |
| 2006 | 21.40 | +60.66% |
| 2005 | 13.32 | +78.31% |
| 2004* | 7.47 | -2.73% |
* Partial year: the record begins after the start of 2004; return measured from the first available close.
2026 return is year to date.
ALNY daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 224.74 | 232.86 | 222.71 | 232.68 | +3.63% | |
| 222.05 | 225.90 | 218.39 | 224.53 | +0.05% | |
| 224.39 | 230.42 | 222.46 | 224.41 | +0.21% | |
| 221.02 | 229.18 | 217.18 | 223.94 | +1.84% | |
| 218.36 | 222.08 | 215.46 | 219.89 | +0.08% | |
| 231.31 | 231.36 | 219.40 | 219.72 | -4.96% | |
| 248.21 | 251.71 | 230.06 | 231.18 | -6.31% | |
| 253.68 | 254.44 | 246.66 | 246.74 | -2.89% | |
| 254.86 | 257.27 | 251.02 | 254.07 | -0.51% | |
| 256.28 | 256.60 | 248.12 | 255.36 | -0.23% | |
| 248.39 | 256.66 | 247.51 | 255.96 | +2.55% | |
| 246.51 | 251.81 | 245.52 | 249.59 | +1.25% | |
| 249.99 | 253.81 | 245.34 | 246.51 | -2.04% | |
| 246.86 | 255.51 | 244.13 | 251.65 | +3.00% | |
| 240.37 | 247.10 | 237.97 | 244.32 | +1.99% | |
| 246.41 | 246.49 | 238.51 | 239.56 | -2.42% | |
| 242.60 | 245.63 | 239.50 | 245.51 | +2.57% | |
| 239.50 | 242.24 | 236.00 | 239.36 | +0.46% | |
| 246.99 | 247.43 | 237.44 | 238.27 | -4.69% | |
| 250.17 | 252.79 | 244.18 | 249.99 | +0.53% | |
| 248.05 | 254.08 | 246.01 | 248.68 | +0.47% | |
| 256.68 | 256.68 | 246.42 | 247.51 | -4.07% | |
| 257.07 | 261.98 | 253.28 | 258.00 | -0.81% | |
| 259.00 | 272.08 | 254.01 | 260.10 | -2.26% | |
| 258.58 | 266.85 | 258.02 | 266.11 | +0.61% | |
| 265.94 | 271.19 | 261.54 | 264.50 | -1.08% | |
| 246.48 | 269.94 | 246.48 | 267.40 | +8.65% | |
| 242.40 | 248.13 | 238.00 | 246.11 | +2.25% | |
| 235.94 | 243.02 | 233.33 | 240.69 | +1.51% | |
| 224.47 | 239.08 | 223.61 | 237.10 | +0.23% | |
| 236.56 | 238.00 | 230.46 | 236.56 | -1.02% | |
| 238.54 | 242.89 | 236.60 | 239.00 | -0.45% | |
| 236.56 | 240.67 | 235.41 | 240.08 | +1.72% | |
| 235.83 | 237.91 | 228.59 | 236.01 | -0.09% | |
| 228.88 | 238.97 | 228.34 | 236.22 | +3.02% | |
| 239.00 | 240.88 | 228.74 | 229.30 | -5.49% | |
| 234.36 | 244.03 | 233.40 | 242.61 | +6.12% | |
| 226.27 | 230.91 | 222.01 | 228.61 | +1.79% | |
| 225.76 | 227.99 | 222.12 | 224.60 | -1.77% | |
| 223.52 | 228.98 | 220.23 | 228.65 | +0.67% | |
| 225.95 | 227.54 | 222.70 | 227.12 | +1.42% | |
| 219.00 | 224.66 | 219.00 | 223.95 | +1.24% | |
| 217.41 | 223.44 | 216.50 | 221.20 | +1.94% | |
| 218.00 | 223.50 | 215.61 | 216.98 | -1.01% | |
| 217.31 | 219.64 | 210.49 | 219.20 | +1.43% | |
| 228.58 | 234.00 | 212.98 | 216.12 | -5.51% | |
| 221.74 | 229.65 | 221.50 | 228.72 | +4.44% | |
| 220.33 | 222.59 | 215.07 | 219.00 | -0.60% | |
| 208.04 | 220.49 | 208.04 | 220.33 | +7.21% | |
| 205.46 | 207.99 | 200.11 | 205.52 | +0.02% | |
| 225.02 | 230.00 | 197.81 | 205.48 | -28.31% | |
| 288.09 | 290.60 | 284.15 | 286.62 | -0.62% | |
| 282.79 | 290.47 | 281.23 | 288.41 | +3.60% | |
| 272.66 | 284.68 | 272.66 | 278.40 | +2.44% | |
| 268.74 | 275.58 | 265.64 | 271.77 | +1.13% | |
| 265.95 | 269.22 | 262.21 | 268.74 | +0.66% | |
| 270.84 | 273.72 | 264.21 | 266.99 | -1.61% | |
| 272.40 | 278.30 | 270.01 | 271.37 | -0.48% | |
| 267.55 | 275.25 | 266.27 | 272.67 | +1.94% | |
| 280.99 | 284.36 | 266.43 | 267.47 | -5.54% | |
| 279.65 | 286.60 | 273.78 | 283.15 | +1.44% | |
| 281.70 | 284.80 | 275.84 | 279.14 | -0.75% | |
| 283.55 | 286.76 | 279.43 | 281.26 | -2.36% | |
| 298.01 | 298.76 | 279.41 | 288.06 | -3.58% | |
| 314.71 | 322.49 | 293.78 | 298.76 | -4.49% | |
| 378.49 | 380.00 | 311.10 | 312.79 | -3.31% | |
| 318.50 | 325.37 | 316.78 | 323.50 | +0.59% | |
| 317.07 | 321.98 | 315.35 | 321.59 | +2.73% | |
| 319.34 | 319.34 | 307.13 | 313.04 | +0.08% | |
| 303.87 | 317.17 | 303.00 | 312.78 | +3.68% | |
| 304.54 | 309.28 | 301.50 | 301.67 | +0.21% | |
| 296.82 | 302.74 | 295.18 | 301.03 | +2.56% | |
| 296.97 | 298.28 | 291.90 | 293.52 | +0.74% | |
| 297.57 | 302.96 | 290.37 | 291.37 | -0.61% | |
| 293.68 | 298.35 | 290.07 | 293.17 | -0.30% | |
| 290.95 | 303.46 | 288.85 | 294.06 | +2.04% | |
| 290.89 | 291.95 | 285.26 | 288.18 | +0.62% | |
| 278.42 | 286.67 | 278.17 | 286.41 | +2.99% | |
| 280.11 | 282.98 | 273.11 | 278.09 | -1.64% | |
| 281.31 | 288.00 | 277.78 | 282.72 | +0.29% | |
| 288.13 | 288.48 | 276.94 | 281.90 | -2.05% | |
| 282.92 | 288.11 | 281.36 | 287.80 | +1.75% | |
| 288.96 | 291.28 | 281.77 | 282.85 | -2.26% | |
| 290.70 | 292.98 | 285.22 | 289.39 | -0.63% | |
| 297.69 | 299.70 | 290.53 | 291.22 | -2.17% | |
| 297.31 | 302.85 | 293.97 | 297.69 | +1.89% | |
| 303.11 | 303.57 | 285.54 | 292.16 | -3.59% | |
| 306.34 | 306.73 | 300.50 | 303.05 | -0.19% | |
| 297.22 | 310.53 | 293.85 | 303.64 | +3.78% | |
| 284.48 | 293.16 | 283.10 | 292.58 | +2.26% | |
| 293.94 | 295.60 | 285.00 | 286.12 | -3.22% | |
| 299.51 | 303.98 | 295.13 | 295.63 | -2.10% | |
| 302.43 | 305.68 | 297.62 | 301.98 | -1.01% | |
| 293.00 | 305.98 | 291.84 | 305.06 | +3.19% | |
| 293.40 | 299.98 | 292.91 | 295.63 | +0.04% | |
| 299.00 | 301.09 | 294.26 | 295.50 | -0.66% | |
| 299.12 | 303.33 | 294.99 | 297.45 | -1.02% | |
| 296.64 | 301.43 | 293.00 | 300.51 | +0.68% | |
| 297.80 | 300.08 | 292.10 | 298.48 | +1.42% | |
| 289.00 | 294.93 | 284.38 | 294.30 | +2.81% | |
| 287.14 | 291.97 | 285.26 | 286.27 | -0.25% | |
| 294.78 | 298.00 | 286.76 | 286.98 | -2.20% | |
| 290.72 | 297.00 | 287.51 | 293.45 | +0.68% | |
| 290.70 | 298.38 | 288.56 | 291.48 | -0.19% | |
| 288.66 | 295.86 | 286.73 | 292.03 | +2.52% | |
| 294.15 | 296.37 | 284.28 | 284.84 | -3.46% | |
| 295.91 | 300.17 | 293.06 | 295.05 | -0.29% | |
| 300.55 | 303.46 | 293.78 | 295.91 | -2.34% | |
| 301.57 | 306.03 | 298.96 | 303.00 | +0.63% | |
| 297.81 | 302.67 | 295.02 | 301.11 | +1.07% | |
| 298.00 | 300.49 | 288.06 | 297.93 | +0.61% | |
| 308.76 | 311.88 | 295.79 | 296.11 | -4.32% | |
| 307.48 | 317.56 | 287.00 | 309.49 | +2.76% | |
| 300.48 | 304.22 | 294.06 | 301.19 | -0.30% | |
| 308.97 | 314.17 | 301.80 | 302.11 | -2.07% | |
| 303.87 | 314.74 | 303.70 | 308.51 | +0.97% | |
| 309.63 | 311.10 | 302.90 | 305.54 | -2.63% | |
| 313.59 | 315.83 | 310.79 | 313.79 | +1.03% | |
| 308.43 | 312.69 | 307.85 | 310.58 | +0.70% | |
| 307.32 | 310.50 | 301.63 | 308.43 | -0.81% | |
| 306.56 | 312.25 | 305.00 | 310.94 | +0.41% | |
| 326.09 | 326.53 | 306.00 | 309.66 | -3.27% | |
| 333.39 | 333.39 | 318.93 | 320.13 | -3.98% | |
| 341.63 | 342.23 | 331.02 | 333.39 | -1.77% | |
| 330.81 | 343.36 | 330.54 | 339.41 | +1.92% | |
| 320.66 | 333.56 | 319.00 | 333.00 | +3.38% | |
| 323.49 | 328.93 | 317.53 | 322.11 | +0.26% | |
| 325.67 | 326.90 | 318.77 | 321.28 | -1.82% | |
| 327.49 | 330.30 | 324.44 | 327.25 | +2.42% | |
| 319.48 | 322.35 | 313.54 | 319.52 | -3.28% | |
| 320.10 | 335.58 | 320.10 | 330.34 | +3.60% | |
| 323.03 | 325.49 | 315.90 | 318.85 | -3.01% | |
| 332.69 | 335.48 | 327.59 | 328.73 | -0.65% | |
| 319.06 | 332.48 | 318.37 | 330.87 | +4.68% | |
| 319.32 | 321.76 | 314.21 | 316.09 | -0.40% | |
| 327.10 | 329.69 | 316.85 | 317.36 | -3.29% | |
| 328.90 | 332.81 | 327.69 | 328.16 | -0.16% | |
| 313.34 | 329.48 | 311.71 | 328.70 | +6.70% | |
| 303.42 | 308.91 | 299.62 | 308.05 | +0.45% | |
| 320.77 | 323.23 | 304.38 | 306.66 | -1.77% | |
| 311.05 | 322.43 | 311.05 | 312.17 | +0.34% | |
| 316.42 | 317.61 | 309.73 | 311.10 | -1.18% | |
| 317.50 | 319.27 | 312.58 | 314.80 | -1.75% | |
| 319.63 | 326.96 | 317.53 | 320.42 | +0.47% | |
| 311.22 | 319.55 | 311.22 | 318.91 | +1.75% | |
| 319.00 | 319.50 | 309.92 | 313.41 | -1.20% | |
| 320.53 | 321.00 | 309.61 | 317.23 | -1.00% | |
| 322.00 | 323.71 | 317.75 | 320.43 | -0.60% | |
| 325.60 | 326.18 | 317.03 | 322.38 | -0.37% | |
| 317.25 | 323.68 | 313.12 | 323.59 | +0.91% | |
| 317.73 | 321.17 | 312.09 | 320.66 | +0.05% | |
| 323.69 | 328.28 | 319.51 | 320.51 | -2.07% | |
| 319.20 | 328.00 | 317.25 | 327.30 | +2.71% | |
| 321.37 | 324.06 | 315.20 | 318.65 | -1.97% | |
| 329.41 | 334.42 | 323.16 | 325.07 | -2.36% | |
| 331.24 | 334.80 | 328.39 | 332.92 | +0.51% | |
| 328.67 | 333.47 | 322.00 | 331.24 | +1.19% | |
| 332.76 | 334.42 | 325.24 | 327.36 | -1.65% | |
| 328.22 | 333.07 | 324.48 | 332.85 | +1.06% | |
| 335.73 | 341.39 | 326.76 | 329.35 | -2.03% | |
| 336.58 | 345.90 | 335.83 | 336.19 | -0.94% | |
| 332.24 | 339.61 | 326.33 | 339.37 | +2.01% | |
| 328.86 | 335.80 | 324.53 | 332.68 | +0.02% | |
| 316.80 | 336.21 | 315.63 | 332.61 | +5.79% | |
| 302.55 | 318.44 | 302.55 | 314.40 | +1.92% | |
| 314.42 | 315.51 | 298.00 | 308.48 | -4.28% | |
| 322.14 | 325.04 | 317.80 | 322.28 | -0.22% | |
| 322.68 | 325.98 | 317.89 | 322.98 | +0.93% | |
| 325.49 | 329.92 | 319.26 | 320.00 | -2.49% | |
| 331.61 | 340.07 | 326.51 | 328.16 | -0.93% | |
| 350.50 | 350.50 | 327.27 | 331.24 | -5.89% | |
| 354.00 | 355.49 | 347.08 | 351.96 | +0.05% | |
| 338.49 | 352.82 | 337.59 | 351.80 | +3.74% | |
| 337.42 | 342.33 | 333.00 | 339.11 | +0.31% | |
| 343.10 | 346.50 | 336.39 | 338.06 | -2.52% | |
| 349.37 | 350.34 | 345.01 | 346.79 | -0.80% | |
| 353.66 | 356.84 | 348.00 | 349.58 | -1.46% | |
| 361.55 | 368.07 | 354.69 | 354.75 | -1.83% | |
| 357.98 | 364.07 | 352.50 | 361.35 | +0.94% | |
| 368.20 | 371.33 | 356.72 | 357.98 | -3.25% | |
| 365.50 | 376.87 | 363.36 | 370.00 | +1.24% | |
| 353.01 | 366.00 | 351.55 | 365.46 | +2.79% | |
| 350.70 | 355.74 | 347.77 | 355.53 | -1.04% | |
| 362.29 | 367.20 | 355.46 | 359.27 | +0.00% | |
| 368.54 | 372.82 | 356.83 | 359.26 | -2.07% | |
| 369.95 | 371.71 | 359.95 | 366.86 | -0.84% | |
| 369.10 | 376.88 | 366.92 | 369.96 | -0.26% | |
| 377.82 | 378.61 | 353.52 | 370.91 | -6.87% | |
| 399.40 | 409.58 | 392.56 | 398.29 | -0.28% | |
| 420.18 | 425.19 | 393.48 | 399.40 | -5.47% | |
| 405.51 | 427.05 | 405.51 | 422.50 | +3.96% | |
| 396.23 | 409.18 | 384.42 | 406.40 | +2.15% | |
| 397.57 | 400.00 | 383.84 | 397.83 | -0.58% | |
| 399.34 | 407.22 | 396.08 | 400.17 | +0.63% | |
| 397.25 | 402.44 | 397.25 | 397.65 | +0.10% | |
| 394.81 | 398.40 | 393.64 | 397.25 | -0.39% | |
| 400.10 | 402.72 | 397.05 | 398.82 | -0.44% | |
| 404.58 | 404.58 | 397.31 | 400.59 | -0.02% | |
| 395.99 | 401.47 | 395.05 | 400.69 | +0.50% | |
| 404.72 | 407.43 | 395.99 | 398.70 | -2.21% | |
| 409.60 | 413.59 | 403.20 | 407.73 | +1.87% | |
| 399.11 | 408.15 | 395.97 | 400.23 | +1.06% | |
| 394.49 | 404.19 | 391.51 | 396.04 | +1.00% | |
| 394.18 | 400.24 | 389.00 | 392.10 | +0.24% | |
| 390.65 | 399.64 | 388.54 | 391.17 | -0.08% | |
| 394.22 | 402.33 | 390.00 | 391.50 | -1.52% | |
| 408.86 | 410.04 | 387.03 | 397.55 | -3.65% | |
| 403.36 | 414.22 | 402.22 | 412.63 | +2.02% | |
| 416.54 | 417.00 | 403.80 | 404.46 | -2.59% | |
| 430.45 | 433.31 | 412.31 | 415.21 | -3.44% | |
| 447.00 | 449.78 | 423.45 | 430.02 | -6.13% | |
| 468.29 | 473.50 | 455.32 | 458.12 | -1.55% | |
| 472.67 | 477.06 | 463.03 | 465.34 | -1.68% | |
| 466.49 | 479.79 | 460.41 | 473.29 | +1.80% | |
| 453.90 | 472.48 | 453.01 | 464.93 | +2.28% | |
| 450.00 | 462.93 | 448.27 | 454.56 | +0.74% | |
| 448.18 | 455.76 | 444.43 | 451.23 | +1.37% | |
| 432.87 | 447.69 | 430.27 | 445.12 | +3.56% | |
| 436.84 | 441.82 | 428.57 | 429.80 | -1.02% | |
| 439.46 | 444.67 | 420.30 | 434.23 | -0.49% | |
| 448.23 | 449.53 | 433.50 | 436.38 | -2.11% | |
| 463.32 | 467.73 | 445.34 | 445.79 | -3.25% | |
| 462.27 | 465.32 | 456.90 | 460.76 | -0.33% | |
| 458.15 | 469.11 | 456.27 | 462.30 | +0.38% | |
| 449.00 | 463.92 | 449.00 | 460.54 | +2.53% | |
| 453.87 | 461.96 | 448.28 | 449.16 | -1.06% | |
| 450.67 | 456.14 | 447.12 | 453.97 | +0.27% | |
| 450.63 | 459.27 | 446.71 | 452.74 | +0.17% | |
| 443.53 | 455.20 | 441.21 | 451.95 | +2.32% | |
| 445.00 | 449.68 | 440.93 | 441.70 | -0.23% | |
| 437.81 | 443.69 | 430.84 | 442.70 | +0.50% | |
| 431.78 | 445.50 | 429.00 | 440.49 | +1.36% | |
| 422.11 | 438.53 | 417.00 | 434.56 | +2.62% | |
| 429.90 | 431.50 | 421.83 | 423.47 | -2.44% | |
| 454.58 | 457.26 | 429.60 | 434.07 | -4.82% | |
| 449.00 | 459.77 | 441.22 | 456.04 | +1.44% | |
| 450.00 | 472.36 | 436.51 | 449.56 | -6.65% | |
| 475.19 | 482.73 | 467.09 | 481.59 | +1.19% | |
| 476.50 | 484.61 | 473.29 | 475.91 | -0.56% | |
| 465.56 | 485.36 | 465.55 | 478.58 | +3.27% | |
| 468.68 | 469.29 | 459.38 | 463.43 | -0.12% | |
| 464.71 | 468.86 | 456.90 | 464.00 | -0.19% | |
| 477.66 | 480.53 | 461.21 | 464.90 | -1.92% | |
| 488.42 | 490.05 | 471.40 | 474.00 | -3.51% | |
| 476.82 | 495.55 | 476.82 | 491.22 | +1.98% | |
| 481.65 | 492.62 | 476.44 | 481.67 | +0.12% | |
| 474.39 | 488.39 | 470.46 | 481.07 | +2.30% | |
| 469.19 | 485.28 | 467.50 | 470.27 | +0.19% | |
| 462.13 | 479.69 | 457.73 | 469.36 | +0.95% | |
| 456.13 | 473.65 | 453.83 | 464.95 | +0.98% | |
| 460.28 | 460.60 | 451.00 | 460.46 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the ALNY chart for longer ranges.