MetaCap

Amylyx Pharmaceuticals Inc. (AMLX)

NASDAQ: AMLXHealth CareBiotechnology: Pharmaceutical PreparationsUSD

27.43-0.61 (-2.18%)

At close: Oct 7, 4:00 PM ET · Delayed 15 min

Pre-market: 27.40 -0.11%

AMLX stock chart

Technical analysis

Key statistics

All statistics
EPS (TTM)
-$1.41
52-week range
10.83 – 41.14
Day range
27.21 – 28.46
Volume / Avg
2.06M / 2.33M
Beta
—
Next earnings
Nov 5, 2026

52-week range

$10.83$41.14

AMLX stock today

Amylyx Pharmaceuticals (AMLX) closed at $27.43 on Oct 7, down 2.18% (-$0.61), versus the S&P 500's 0.22% decline. At this level, AMLX sits in the middle of its 52-week range of $10.83 to $41.14: 33.3% below the high, set on Aug 21, 2026 and 153.3% above the low. AMLX is up 127.1% year to date, outperforming the S&P 500 (+14.0%). Over the past 12 months, the stock has gained 103.3%.

Amylyx Pharmaceuticals has posted a net loss over the last twelve months (EPS of -$1.41), so its P/E ratio is not meaningful. Amylyx Pharmaceuticals's next earnings report is expected on Nov 5, 2026.

Summary generated from market data by MetaCap's automated system. Methodology

About Amylyx Pharmaceuticals

Company profile

Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phase 2 clinical trial for the treatment of wolfram syndrome, as well as in phase 2b/3 clinical trial to treat progressive supranuclear palsy; AMX0114, which is in phase 1 clinical trial for the treatment of amyotrophic lateral sclerosis; and long-acting GLP-1 receptor antagonist to treat post-bariatric hypoglycemia and other rare diseases.

Industry
Biotechnology: Pharmaceutical Preparations
CEO
Mr. Joshua B. Cohen
Headquarters
Cambridge, MA
Employees
136
IPO year
2022
Website
amylyx.com

Financial highlights

Full financials

In fiscal 2025, Amylyx Pharmaceuticals generated $0 in revenue, down 100.0% from fiscal 2024, its first annual decline since 2024. Amylyx Pharmaceuticals reported a net loss of $144.7 million, compared with a loss of $301.7 million a year earlier. Diluted earnings per share came in at -$1.53.

Amylyx Pharmaceuticals annual revenue, net income and EPS
Fiscal yearFY 2025FY 2024FY 2023FY 2022FY 2021
Revenue$0$87.37M$380.79M$22.23M$285.00K
Growth-100.00%-77.06%+1612.94%+7700.00%—
Net income$-144.74M$-301.74M$49.27M$-198.38M$-87.93M
EPS (diluted)$-1.53$-4.43$0.70$-3.39$-13.35

Analyst forecast

Forecast

Consensus (12 analysts)

strong_buy

Avg. price target

$42.36+54.43%

  • Strong buy 0
  • Buy 11
  • Hold 1
  • Sell 0
  • Strong sell 0

Target range

Low $20.00High $57.00

Ratings and targets reflect third-party analyst opinions, not MetaCap recommendations.

Earnings

Earnings history
Next report
Nov 5, 2026
EPS estimate
$-0.38
Last reported (Q2 2026)
Aug 6, 2026
EPS actual vs est.
$-0.39 vs —

Amylyx Pharmaceuticals peers

Health Care sector
AMLX peer companies
CompanyPrice% ChgMarket capCompare
IDYAIDEAYA Biosciences Inc.36.26-1.01%$3.50Bvs AMLX
ACADACADIA Pharmaceuticals Inc.19.65-0.46%$3.39Bvs AMLX
XENEXenon Pharmaceuticals Inc.36.41-0.44%$3.53Bvs AMLX
PBLSParabilis Medicines Inc.28.82-0.14%$3.56Bvs AMLX
OGNOrganon & Co.13.79+0.36%$3.62Bvs AMLX
VKTXViking Therapeutics Inc.28.54+0.56%$3.63Bvs AMLX
TNGXTango Therapeutics Inc.21.83-0.32%$3.68Bvs AMLX
LEGNLegend Biotech Corporation ADR19.12+2.14%$3.72Bvs AMLX

Indexes, lists and sector

Amylyx Pharmaceuticals stock FAQ

What is Amylyx Pharmaceuticals's stock price today?

AMLX last traded at $27.43 as of Oct 7, 4:00 PM EDT, down 2.18% on the day. Prices are delayed at least 15 minutes.

When is Amylyx Pharmaceuticals's next earnings date?

Amylyx Pharmaceuticals is expected to report earnings on Thursday, November 5, 2026. Analysts expect EPS of $-0.38.

Who is Amylyx Pharmaceuticals's CEO?

Mr. Joshua B. Cohen is the chief executive officer of Amylyx Pharmaceuticals Inc., which has about 136 employees.

What is the AMLX 52-week high?

The 52-week high for AMLX is $41.14 and the 52-week low is $10.83. The stock is currently 33.3% below its high.

Compare AMLX