MetaCap

Amylyx Pharmaceuticals (AMLX) Short Interest

NASDAQ: AMLXHealth CareBiotechnology: Pharmaceutical PreparationsUSD

28.14+0.94 (+3.46%)

At close: Oct 9, 4:00 PM ET · Delayed 15 min

Latest short interest · Sep 15, 2026

Change vs prior
+6.1%
Avg. daily volume
1.56M
Prior report
12.74M

Amylyx Pharmaceuticals short interest analysis

As of the Sep 15, 2026 settlement date, 13,512,753 AMLX shares were sold short, equal to 10.77% of Amylyx Pharmaceuticals's shares outstanding. That is up 6.1% from the previous report of 12.74M shares. With average daily volume of 1.56M shares, it would take about 8.6 trading days for short sellers to buy back their positions, which is elevated by typical standards.

The highest reading in the period shown was 14.96M shares on May 29, 2026.

Summary generated from market data by MetaCap's automated system. Methodology

AMLX short interest history

Amylyx Pharmaceuticals short interest by settlement date
SettlementShort InterestChange% Shares Out.Days to Cover
Sep 15, 202613,512,753+6.1%10.77%8.64
Aug 31, 202612,737,201-5.1%10.15%2.37
Aug 14, 202613,425,106+0.2%10.70%7.14
Jul 31, 202613,401,722+9.3%10.68%6.84
Jul 15, 202612,265,993-14.7%9.77%9.21
Jun 30, 202614,385,180+9.6%11.46%7.06
Jun 15, 202613,121,697-12.3%10.45%8.12
May 29, 202614,957,523+3.0%11.92%16.33
May 15, 202614,514,401-1.9%11.56%12.16
Apr 30, 202614,800,969-0.2%11.79%14.26
Apr 15, 202614,831,510+4.2%11.82%12.23
Mar 31, 202614,231,261+2.6%11.34%14.14

Days to cover = shares short ÷ average daily volume. Short percent uses total shares outstanding as the denominator, which is slightly lower than a float-based figure.

Frequently asked questions

What is Amylyx Pharmaceuticals's short interest?

AMLX short interest was 13,512,753 shares as of Sep 15, 2026, or 10.77% of shares outstanding, up 6.1% from the prior report.

What is AMLX's days to cover?

AMLX's days-to-cover (short interest ratio) is 8.64, meaning short sellers would need about 8.6 days of average trading volume to close their positions.

How often is short interest reported?

FINRA requires brokers to report short positions twice a month, as of mid-month and month-end settlement dates. The data is published about a week and a half after each settlement date, so it is always somewhat delayed.

Is high short interest bullish or bearish?

High short interest shows that many investors expect the price to fall, which is a bearish signal. It can also set up a short squeeze if the stock rises and short sellers rush to buy back shares. Neither outcome is guaranteed.

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