Spruce Biosciences Stock Price History
NASDAQ: SPRBHealth CareBiotechnology: Pharmaceutical PreparationsUSD
44.05-1.49 (-3.27%)
At close: Oct 9, 4:00 PM ET · Delayed 15 min
SPRB price history at a glance
The price history for Spruce Biosciences (SPRB) on this page begins on October 5, 2020, when the stock closed at $95,625.00; it most recently closed at $44.05 on October 5, 2026. The highest price in this record is $200,250.00, reached on November 23, 2020; the latest close is 100.0% below that peak. Across the 5 complete calendar years in the table, SPRB finished higher in 1 and lower in 4. Its best year was 2023 (+167.1%) and its worst was 2025 (-96.3%).
Over roughly 6 years the share price changed -100.0%, a -72.2% compound annual price return (excluding dividends). In the last 12 months alone, SPRB has lost 74.9%. Prices are split-adjusted closing prices; daily open, high, low, close and volume for the past year are listed below.
Summary generated from market data by MetaCap's automated system. Methodology
Key price levels
- High since 2020
- $200,250.00
- Date of high
- Nov 23, 2020
- Low since 2020
- $7.00
- Date of low
- Aug 25, 2025
- 52-week high
- $188.25
- 52-week low
- $40.33
- IPO year
- 2020
- Last close
- $44.05
SPRB returns
1 week
-3.63%
1 month
-20.97%
3 months
-12.02%
6 months
-30.77%
Year to date
-49.43%
1 year
-74.87%
3 years
-99.49%
5 years
-99.82%
SPRB price return, excluding dividends.
SPRB annual returns
| Year | Year-end close | Return |
|---|---|---|
| 2026 | 44.05 | -51.43% |
| 2025 | 90.70 | -96.25% |
| 2024 | 2,418.75 | -85.32% |
| 2023 | 16,481.25 | +167.09% |
| 2022 | 6,170.63 | -75.40% |
| 2021 | 25,087.50 | -81.65% |
| 2020* | 136,743.75 | +43.00% |
* Partial year: the record begins after the start of 2020; return measured from the first available close.
2026 return is year to date.
SPRB daily prices (past year)
| Date | Open | High | Low | Close | Change |
|---|---|---|---|---|---|
| 44.50 | 45.04 | 42.80 | 44.05 | -3.27% | |
| 43.50 | 45.62 | 43.34 | 45.54 | +2.57% | |
| 42.56 | 45.40 | 42.37 | 44.40 | +3.77% | |
| 45.60 | 46.72 | 42.50 | 42.79 | -5.80% | |
| 45.51 | 46.80 | 43.83 | 45.42 | -0.63% | |
| 46.58 | 47.73 | 44.13 | 45.71 | +2.10% | |
| 48.15 | 49.20 | 44.47 | 44.77 | -7.84% | |
| 47.78 | 49.95 | 47.76 | 48.58 | +2.77% | |
| 47.55 | 48.00 | 46.55 | 47.27 | -0.51% | |
| 48.28 | 48.99 | 47.01 | 47.51 | -2.48% | |
| 49.22 | 49.31 | 47.54 | 48.72 | -0.61% | |
| 49.01 | 49.50 | 47.58 | 49.02 | -0.80% | |
| 50.50 | 50.74 | 45.01 | 49.42 | -1.15% | |
| 54.05 | 54.98 | 49.23 | 49.99 | -6.91% | |
| 53.84 | 55.06 | 53.07 | 53.70 | +1.23% | |
| 53.04 | 53.86 | 51.80 | 53.05 | -1.50% | |
| 56.22 | 57.11 | 53.28 | 53.86 | -0.55% | |
| 55.01 | 56.27 | 53.26 | 54.16 | -1.82% | |
| 55.99 | 56.36 | 54.51 | 55.17 | -2.96% | |
| 53.28 | 57.55 | 52.66 | 56.85 | +5.87% | |
| 54.78 | 56.08 | 53.09 | 53.70 | -1.20% | |
| 55.61 | 57.50 | 54.03 | 54.35 | -2.49% | |
| 58.52 | 59.01 | 55.70 | 55.74 | -5.67% | |
| 57.39 | 60.51 | 56.60 | 59.09 | +2.00% | |
| 57.37 | 58.19 | 56.57 | 57.93 | +0.38% | |
| 59.76 | 60.32 | 57.30 | 57.71 | -3.28% | |
| 56.52 | 60.13 | 56.52 | 59.67 | +7.32% | |
| 58.01 | 58.05 | 55.34 | 55.60 | -5.71% | |
| 60.54 | 60.90 | 57.58 | 58.97 | -2.98% | |
| 62.12 | 62.98 | 59.90 | 60.78 | -3.98% | |
| 62.00 | 63.56 | 60.55 | 63.30 | +2.96% | |
| 64.50 | 64.50 | 60.46 | 61.48 | -3.03% | |
| 58.82 | 64.15 | 58.00 | 63.40 | +8.10% | |
| 53.04 | 58.92 | 51.16 | 58.65 | +13.71% | |
| 52.48 | 53.00 | 49.03 | 51.58 | -0.78% | |
| 52.83 | 52.89 | 50.50 | 51.99 | -1.84% | |
| 54.18 | 54.93 | 52.02 | 52.96 | +0.22% | |
| 51.31 | 53.95 | 50.80 | 52.85 | -0.14% | |
| 51.57 | 53.60 | 48.92 | 52.92 | +0.53% | |
| 50.14 | 52.64 | 48.55 | 52.64 | +5.77% | |
| 47.33 | 51.25 | 47.31 | 49.77 | +5.74% | |
| 46.95 | 49.00 | 46.26 | 47.07 | +1.42% | |
| 46.41 | 47.45 | 46.11 | 46.41 | +0.45% | |
| 46.69 | 46.69 | 45.01 | 46.20 | -1.43% | |
| 47.00 | 47.43 | 45.88 | 46.87 | +0.97% | |
| 46.38 | 47.41 | 45.24 | 46.42 | -0.41% | |
| 46.80 | 47.13 | 45.35 | 46.61 | +0.76% | |
| 44.50 | 46.34 | 43.68 | 46.26 | +7.23% | |
| 42.02 | 44.38 | 41.46 | 43.14 | +0.72% | |
| 43.06 | 43.30 | 42.00 | 42.83 | -1.25% | |
| 41.99 | 43.49 | 41.99 | 43.37 | +4.63% | |
| 41.07 | 43.08 | 40.55 | 41.45 | -0.36% | |
| 42.16 | 43.29 | 40.33 | 41.60 | -0.93% | |
| 42.64 | 45.51 | 41.98 | 41.99 | -2.53% | |
| 44.30 | 45.00 | 41.53 | 43.08 | -4.25% | |
| 44.16 | 45.06 | 42.51 | 44.99 | +0.87% | |
| 45.27 | 45.28 | 44.16 | 44.60 | -2.36% | |
| 44.26 | 46.27 | 44.26 | 45.68 | +2.65% | |
| 44.21 | 45.41 | 43.25 | 44.50 | +2.20% | |
| 43.24 | 45.75 | 42.70 | 43.54 | -1.67% | |
| 45.20 | 45.54 | 43.27 | 44.28 | -2.55% | |
| 47.50 | 48.50 | 44.69 | 45.44 | -1.98% | |
| 49.34 | 49.98 | 46.19 | 46.36 | -4.18% | |
| 51.57 | 52.85 | 48.10 | 48.38 | -3.38% | |
| 51.38 | 51.98 | 49.26 | 50.07 | -3.23% | |
| 50.82 | 51.99 | 49.83 | 51.74 | +3.90% | |
| 50.69 | 51.37 | 48.61 | 49.80 | -1.91% | |
| 52.00 | 52.57 | 49.70 | 50.77 | -2.08% | |
| 53.40 | 54.22 | 51.60 | 51.85 | -1.26% | |
| 52.81 | 55.21 | 51.03 | 52.51 | -0.07% | |
| 53.04 | 54.94 | 50.86 | 52.55 | -2.69% | |
| 55.32 | 56.80 | 53.49 | 54.00 | -3.36% | |
| 55.17 | 57.00 | 54.05 | 55.88 | +1.40% | |
| 51.84 | 55.35 | 51.78 | 55.11 | +4.43% | |
| 52.00 | 53.67 | 50.11 | 52.77 | +1.74% | |
| 52.50 | 52.51 | 50.39 | 51.87 | -0.52% | |
| 53.49 | 55.10 | 52.14 | 52.14 | -4.68% | |
| 52.05 | 55.95 | 52.00 | 54.70 | +4.47% | |
| 49.48 | 52.90 | 49.48 | 52.36 | +7.38% | |
| 47.72 | 51.60 | 46.49 | 48.76 | +3.52% | |
| 50.92 | 51.52 | 47.10 | 47.10 | -5.62% | |
| 51.79 | 52.13 | 48.61 | 49.91 | -3.83% | |
| 49.18 | 53.25 | 49.02 | 51.89 | +5.67% | |
| 47.01 | 49.88 | 46.50 | 49.11 | +4.19% | |
| 48.53 | 50.38 | 47.13 | 47.13 | -3.88% | |
| 50.72 | 52.18 | 46.70 | 49.03 | -0.59% | |
| 50.69 | 51.10 | 48.67 | 49.32 | -2.20% | |
| 53.22 | 53.22 | 48.64 | 50.43 | -5.15% | |
| 50.02 | 54.32 | 50.02 | 53.17 | +8.40% | |
| 48.09 | 50.75 | 48.00 | 49.05 | -0.51% | |
| 50.70 | 50.70 | 48.58 | 49.30 | -2.76% | |
| 50.92 | 53.08 | 50.01 | 50.70 | -1.11% | |
| 48.92 | 51.91 | 47.49 | 51.27 | +4.23% | |
| 50.33 | 51.51 | 48.00 | 49.19 | -0.67% | |
| 51.10 | 52.62 | 49.52 | 49.52 | -4.42% | |
| 52.42 | 54.06 | 51.10 | 51.81 | +1.44% | |
| 52.04 | 55.32 | 50.40 | 51.08 | -3.08% | |
| 50.51 | 53.00 | 49.55 | 52.70 | +2.30% | |
| 49.89 | 52.71 | 49.00 | 51.52 | +6.77% | |
| 51.53 | 51.61 | 48.25 | 48.25 | -6.15% | |
| 52.60 | 54.20 | 50.40 | 51.41 | -4.41% | |
| 57.92 | 57.92 | 53.30 | 53.78 | -8.85% | |
| 57.91 | 59.00 | 56.70 | 59.00 | +2.52% | |
| 55.67 | 59.20 | 55.67 | 57.55 | +1.56% | |
| 55.75 | 57.71 | 53.82 | 56.67 | +0.47% | |
| 57.53 | 58.38 | 55.65 | 56.40 | -0.18% | |
| 57.50 | 57.50 | 56.20 | 56.50 | -0.12% | |
| 57.08 | 57.39 | 55.55 | 56.57 | -2.25% | |
| 60.27 | 60.27 | 57.26 | 57.87 | -2.48% | |
| 60.08 | 60.08 | 58.01 | 59.34 | -0.05% | |
| 56.51 | 59.84 | 56.51 | 59.37 | +3.65% | |
| 57.23 | 57.51 | 55.88 | 57.28 | -0.07% | |
| 54.90 | 58.14 | 54.90 | 57.32 | +3.24% | |
| 54.90 | 57.36 | 54.33 | 55.52 | +1.37% | |
| 56.88 | 57.17 | 53.75 | 54.77 | -4.21% | |
| 56.09 | 58.29 | 55.38 | 57.18 | +5.17% | |
| 53.64 | 55.90 | 53.50 | 54.37 | +0.67% | |
| 54.29 | 55.89 | 52.25 | 54.01 | +3.15% | |
| 56.75 | 56.75 | 52.01 | 52.36 | +1.30% | |
| 58.00 | 58.69 | 51.36 | 51.69 | -26.05% | |
| 70.61 | 70.68 | 67.67 | 69.90 | -0.58% | |
| 68.51 | 74.00 | 68.51 | 70.30 | +3.53% | |
| 68.89 | 70.95 | 66.66 | 67.90 | -2.05% | |
| 68.01 | 71.46 | 66.82 | 69.32 | +2.24% | |
| 65.57 | 68.85 | 59.25 | 67.80 | +5.10% | |
| 63.24 | 68.48 | 61.98 | 64.51 | +1.38% | |
| 65.75 | 66.87 | 63.32 | 63.63 | -3.61% | |
| 63.50 | 68.00 | 63.50 | 66.01 | +3.71% | |
| 63.52 | 66.47 | 60.34 | 63.65 | +2.41% | |
| 63.65 | 64.49 | 58.39 | 62.15 | -1.36% | |
| 72.00 | 72.00 | 62.72 | 63.01 | -10.62% | |
| 69.53 | 71.56 | 67.50 | 70.50 | +1.39% | |
| 65.35 | 69.53 | 64.28 | 69.53 | +6.40% | |
| 58.78 | 65.35 | 58.61 | 65.35 | +11.65% | |
| 64.43 | 65.85 | 55.98 | 58.53 | -7.15% | |
| 69.00 | 70.25 | 61.39 | 63.04 | -8.78% | |
| 69.29 | 74.83 | 67.64 | 69.11 | -1.23% | |
| 71.50 | 80.00 | 65.34 | 69.97 | +8.72% | |
| 59.80 | 65.00 | 59.66 | 64.36 | +9.40% | |
| 61.22 | 62.02 | 55.89 | 58.83 | +0.74% | |
| 59.13 | 62.56 | 56.09 | 58.40 | -1.09% | |
| 59.74 | 64.33 | 58.06 | 59.05 | +0.50% | |
| 63.30 | 64.78 | 58.75 | 58.75 | -8.63% | |
| 61.19 | 65.00 | 58.21 | 64.30 | +5.50% | |
| 61.67 | 61.70 | 58.51 | 60.95 | +1.48% | |
| 60.99 | 62.25 | 57.00 | 60.06 | +0.27% | |
| 64.80 | 64.80 | 59.51 | 59.90 | -6.67% | |
| 62.64 | 66.99 | 62.64 | 64.18 | +2.21% | |
| 62.48 | 68.10 | 60.57 | 62.79 | +1.09% | |
| 52.47 | 64.61 | 52.47 | 62.11 | +11.17% | |
| 52.13 | 55.99 | 51.40 | 55.87 | +3.89% | |
| 57.00 | 57.10 | 52.01 | 53.78 | -6.53% | |
| 54.31 | 59.99 | 54.31 | 57.54 | +3.06% | |
| 54.12 | 55.83 | 53.00 | 55.83 | +3.00% | |
| 53.86 | 55.00 | 51.78 | 54.21 | -1.34% | |
| 59.27 | 59.34 | 54.94 | 54.94 | -6.17% | |
| 58.91 | 60.11 | 57.00 | 58.55 | -0.31% | |
| 59.10 | 62.94 | 58.00 | 58.73 | +0.88% | |
| 54.02 | 60.00 | 53.95 | 58.22 | +8.66% | |
| 51.00 | 55.27 | 48.50 | 53.58 | +7.76% | |
| 52.80 | 54.27 | 48.08 | 49.72 | -5.51% | |
| 53.01 | 53.47 | 49.12 | 52.62 | -1.61% | |
| 60.76 | 65.00 | 51.14 | 53.48 | -8.18% | |
| 65.42 | 65.42 | 51.59 | 58.25 | -12.14% | |
| 80.05 | 83.54 | 66.09 | 66.29 | -20.09% | |
| 80.00 | 84.38 | 78.30 | 82.96 | +0.33% | |
| 86.01 | 86.95 | 81.00 | 82.69 | -1.12% | |
| 77.24 | 86.62 | 75.59 | 83.63 | +5.76% | |
| 71.96 | 81.30 | 71.96 | 79.07 | +9.21% | |
| 71.17 | 74.40 | 71.00 | 72.40 | +2.19% | |
| 77.57 | 78.02 | 69.02 | 70.85 | -10.58% | |
| 80.89 | 81.40 | 75.10 | 79.23 | -5.10% | |
| 78.96 | 83.49 | 78.00 | 83.49 | +7.05% | |
| 76.76 | 78.23 | 76.00 | 77.99 | +0.57% | |
| 79.74 | 81.50 | 76.35 | 77.55 | -2.89% | |
| 80.94 | 83.50 | 78.00 | 79.86 | -2.49% | |
| 85.06 | 86.00 | 81.07 | 81.90 | -2.78% | |
| 80.91 | 84.50 | 80.85 | 84.24 | +1.87% | |
| 80.07 | 85.28 | 80.07 | 82.69 | +1.44% | |
| 86.48 | 86.48 | 79.55 | 81.52 | -4.36% | |
| 78.84 | 87.40 | 78.00 | 85.24 | +8.01% | |
| 72.96 | 78.92 | 72.59 | 78.92 | +10.44% | |
| 73.47 | 75.69 | 71.46 | 71.46 | -2.82% | |
| 74.76 | 78.21 | 73.37 | 73.53 | -1.82% | |
| 75.85 | 78.20 | 74.81 | 74.89 | -4.44% | |
| 79.69 | 84.50 | 74.00 | 78.37 | -3.84% | |
| 78.88 | 81.50 | 77.00 | 81.50 | +4.76% | |
| 81.43 | 83.92 | 77.00 | 77.80 | -2.74% | |
| 75.00 | 80.88 | 74.20 | 79.99 | +8.53% | |
| 81.22 | 81.22 | 72.87 | 73.70 | -5.62% | |
| 81.22 | 82.01 | 78.00 | 78.09 | -3.08% | |
| 82.14 | 86.81 | 80.11 | 80.57 | -1.89% | |
| 89.01 | 91.05 | 81.06 | 82.12 | -9.46% | |
| 87.95 | 90.99 | 86.85 | 90.70 | +4.12% | |
| 82.00 | 87.70 | 81.30 | 87.11 | +5.37% | |
| 82.40 | 84.36 | 82.30 | 82.67 | +0.45% | |
| 81.80 | 85.50 | 81.80 | 82.30 | -4.01% | |
| 83.40 | 86.28 | 82.88 | 85.74 | +2.07% | |
| 84.02 | 84.95 | 81.80 | 84.00 | +0.31% | |
| 84.35 | 87.11 | 82.95 | 83.74 | +1.11% | |
| 77.48 | 82.98 | 77.48 | 82.82 | +5.18% | |
| 75.20 | 80.00 | 75.20 | 78.74 | +2.57% | |
| 75.95 | 77.70 | 73.56 | 76.77 | +1.23% | |
| 79.38 | 81.78 | 71.26 | 75.84 | -2.77% | |
| 80.00 | 82.40 | 75.21 | 78.00 | -3.31% | |
| 83.60 | 83.60 | 79.27 | 80.67 | -3.27% | |
| 86.49 | 91.25 | 80.20 | 83.40 | -5.67% | |
| 85.21 | 91.18 | 80.47 | 88.41 | +3.20% | |
| 91.54 | 95.05 | 85.34 | 85.67 | -9.96% | |
| 81.67 | 97.24 | 81.39 | 95.15 | +16.49% | |
| 82.66 | 83.00 | 78.60 | 81.68 | +2.11% | |
| 86.00 | 86.00 | 78.00 | 79.99 | -11.55% | |
| 89.70 | 92.40 | 83.00 | 90.44 | +0.31% | |
| 88.26 | 99.99 | 85.00 | 90.16 | +1.08% | |
| 87.57 | 92.42 | 83.12 | 89.20 | +7.33% | |
| 100.40 | 104.46 | 74.01 | 83.11 | -16.89% | |
| 111.00 | 111.00 | 97.00 | 100.00 | -9.09% | |
| 107.13 | 110.00 | 105.00 | 110.00 | +5.19% | |
| 103.00 | 110.00 | 101.31 | 104.57 | -2.27% | |
| 108.00 | 108.02 | 99.65 | 107.00 | +1.90% | |
| 101.10 | 112.26 | 95.97 | 105.00 | +2.33% | |
| 111.00 | 115.00 | 100.00 | 102.61 | -7.56% | |
| 115.40 | 127.90 | 108.14 | 111.00 | -3.48% | |
| 104.28 | 120.55 | 102.00 | 115.00 | +5.66% | |
| 108.67 | 110.68 | 103.59 | 108.84 | +2.34% | |
| 105.60 | 110.84 | 105.00 | 106.35 | -5.53% | |
| 99.37 | 117.00 | 96.05 | 112.57 | +10.15% | |
| 117.79 | 117.79 | 95.01 | 102.20 | -9.29% | |
| 118.81 | 126.38 | 109.71 | 112.66 | -2.55% | |
| 125.69 | 129.00 | 115.61 | 115.61 | -8.97% | |
| 119.00 | 128.38 | 114.28 | 127.00 | +6.46% | |
| 120.00 | 120.00 | 114.00 | 119.29 | -0.59% | |
| 103.20 | 121.00 | 101.92 | 120.00 | +14.35% | |
| 101.96 | 109.01 | 100.00 | 104.94 | +0.18% | |
| 109.00 | 111.00 | 100.00 | 104.75 | -4.86% | |
| 107.26 | 111.61 | 101.04 | 110.10 | +2.66% | |
| 116.00 | 119.54 | 103.21 | 107.25 | -9.11% | |
| 121.41 | 121.41 | 108.70 | 118.00 | -5.23% | |
| 131.54 | 131.54 | 118.10 | 124.51 | +1.21% | |
| 135.00 | 138.45 | 112.95 | 123.02 | -7.67% | |
| 131.03 | 137.38 | 130.01 | 133.24 | +2.56% | |
| 136.91 | 140.45 | 128.44 | 129.92 | -7.55% | |
| 128.54 | 144.00 | 128.54 | 140.53 | +8.48% | |
| 148.00 | 148.88 | 129.54 | 129.54 | -12.57% | |
| 153.44 | 154.95 | 143.00 | 148.16 | -6.12% | |
| 155.77 | 159.41 | 151.83 | 157.82 | +0.77% | |
| 161.10 | 163.00 | 150.00 | 156.61 | -1.54% | |
| 171.59 | 179.95 | 158.00 | 159.06 | -10.09% | |
| 156.69 | 188.25 | 156.69 | 176.91 | +11.26% | |
| 179.99 | 182.97 | 152.00 | 159.01 | -8.40% | |
| 177.95 | 199.20 | 161.86 | 173.60 | -0.98% | |
| 158.50 | 180.00 | 140.50 | 175.31 | — |
Prices are adjusted for stock splits. See adjusted closing price for how dividends and splits affect history, and the SPRB chart for longer ranges.