Biofrontera (BFRI) vs Shuttle Pharmaceuticals (SHPH)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
Biofrontera (BFRI) has outperformed Shuttle Pharmaceuticals (SHPH) over the past year, losing 9.0% versus a loss of 87.4%. Shuttle Pharmaceuticals is the larger company by market cap ($26.4 million vs $13.6 million), about 1.9 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | BFRI | SHPH |
|---|---|---|
| Share price | $0.9188 | $5.55 |
| Market cap | $13.65M | $26.44M |
| 1-day change | -1.77% | +17.83% |
| YTD return | +61.19% | -69.17% |
| 1-year return | -9.03% | -87.36% |
| Forward P/E | 2.14 | — |
| EPS (TTM) | $-0.43 | $-16.87 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $1.66 | $55.90 |
| 52-week low | $0.555 | $2.58 |
| Distance from 52-week high | -44.65% | -90.07% |
| Analyst consensus | none | — |
| Avg. price target upside | +553.03% | — |
| Average volume | 547.45K | 1.36M |
| Shares outstanding | 14.85M | 4.76M |
| Employees | 84 | 2 |
| Sector | Healthcare | Healthcare |
| Industry | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- BFRI has outperformed SHPH by 78.3 percentage points over the past year.
About Biofrontera
BFRI stock →Biofrontera Inc., a biopharmaceutical company, engages in the commercialization of pharmaceutical products for the treatment of dermatological conditions in the United States. It offers Ameluz, BF-RhodoLED, RhodoLED XL lamp series, and RhodoLED Lamps, which are used for the treatment of actinic keratosis, which are pre-cancerous skin lesions.
Healthcare · Drug Manufacturers - Specialty & Generic · 84 employees
About Shuttle Pharmaceuticals
SHPH stock →Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to treat cancers. It owns a pharmaceutical software artificial intelligence (AI) driven platform for molecular discovery and early-stage drug development.
Healthcare · Drug Manufacturers - Specialty & Generic · 2 employees
BFRI vs SHPH FAQ
Which is bigger, Biofrontera or Shuttle Pharmaceuticals?
Shuttle Pharmaceuticals (SHPH) is larger, with a market capitalization of $26.44M compared with $13.65M for Biofrontera (BFRI).
Which stock has performed better over the past year, BFRI or SHPH?
BFRI returned -9.03% over the past 12 months, compared with -87.36% for SHPH (price return, excluding dividends). Past performance does not predict future results.
Are Biofrontera and Shuttle Pharmaceuticals in the same industry?
Yes. Both are classified in the Drug Manufacturers - Specialty & Generic industry within the Healthcare sector.