Biofrontera (BFRI) vs TherapeuticsMD (TXMD)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
TherapeuticsMD (TXMD) has outperformed Biofrontera (BFRI) over the past year, gaining 89.6% versus a loss of 9.0%. TherapeuticsMD is the larger company by market cap ($23.3 million vs $13.6 million), about 1.7 times the size. On valuation, Biofrontera trades at a lower forward P/E (2.1x vs 5.7x for TherapeuticsMD).
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | BFRI | TXMD |
|---|---|---|
| Share price | $0.9188 | $2.01 |
| Market cap | $13.65M | $23.26M |
| 1-day change | -1.77% | +0.50% |
| YTD return | +61.19% | +23.31% |
| 1-year return | -9.03% | +89.62% |
| 5-year return | — | -94.42% |
| Forward P/E | 2.14 | 5.74 |
| EPS (TTM) | $-0.43 | $-0.04 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $1.66 | $2.95 |
| 52-week low | $0.555 | $1.03 |
| Distance from 52-week high | -44.65% | -31.86% |
| Analyst consensus | none | — |
| Avg. price target upside | +553.03% | — |
| Average volume | 547.45K | 23.94K |
| Shares outstanding | 14.85M | 11.57M |
| Employees | 84 | 1 |
| Sector | Healthcare | Healthcare |
| Industry | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- TXMD has outperformed BFRI by 98.7 percentage points over the past year.
About Biofrontera
BFRI stock →Biofrontera Inc., a biopharmaceutical company, engages in the commercialization of pharmaceutical products for the treatment of dermatological conditions in the United States. It offers Ameluz, BF-RhodoLED, RhodoLED XL lamp series, and RhodoLED Lamps, which are used for the treatment of actinic keratosis, which are pre-cancerous skin lesions.
Healthcare · Drug Manufacturers - Specialty & Generic · 84 employees
About TherapeuticsMD
TXMD stock →TherapeuticsMD, Inc. operates as a pharmaceutical royalty company in the United States and internationally.
Healthcare · Drug Manufacturers - Specialty & Generic · 1 employees
BFRI vs TXMD FAQ
Which is bigger, Biofrontera or TherapeuticsMD?
TherapeuticsMD (TXMD) is larger, with a market capitalization of $23.26M compared with $13.65M for Biofrontera (BFRI).
Which stock has performed better over the past year, BFRI or TXMD?
TXMD returned +89.62% over the past 12 months, compared with -9.03% for BFRI (price return, excluding dividends). Past performance does not predict future results.
Are Biofrontera and TherapeuticsMD in the same industry?
Yes. Both are classified in the Drug Manufacturers - Specialty & Generic industry within the Healthcare sector.