MetaCap

Belite Bio (BLTE) vs Rhythm Pharmaceuticals (RYTM)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 7, 2026.

Summary

Belite Bio (BLTE) has outperformed Rhythm Pharmaceuticals (RYTM) over the past year, gaining 101.7% versus a loss of 11.4%. Belite Bio is the larger company by market cap ($6.29 billion vs $6.09 billion), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

BLTE+101.65%RYTM-11.40%
+159%+63%-33%
Oct 7, 20251 yearOct 7, 2026
BLTE+1373.84%RYTM+1312.94%
+1837%+849%-138%
Apr 25, 20225 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

BLTE versus RYTM key metrics
MetricBLTERYTM
Share price$156.08$88.45
Market cap$6.29B$6.09B
1-day change+0.30%-2.56%
YTD return-2.43%-17.37%
1-year return+101.65%-11.40%
5-year return—+682.05%
Forward P/E69.06—
EPS (TTM)$-2.74$-3.12
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)—$189.76M
Revenue growth (YoY)—+45.83%
Net income (latest FY)$-77.61M$-196.54M
Gross margin—89.73%
Operating margin—-101.19%
Net margin—-103.57%
52-week high$200.00$122.20
52-week low$76.50$74.50
Distance from 52-week high-21.96%-27.62%
Analyst consensusnonenone
Avg. price target upside+46.65%+56.69%
Average volume182.25K646.31K
Shares outstanding40.27M68.85M
Employees41414
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • BLTE has outperformed RYTM by 113.1 percentage points over the past year.

About Belite Bio

BLTE stock →

Belite Bio, Inc, a clinical stage biopharmaceutical drug development company, engages in the research and development of novel therapeutics with unmet medical needs in the United States. Its lead product candidate is Tinlarebant (LBS-008), an orally administered, which is in phase 3 clinical trial as an early intervention for maintaining the health and integrity of retinal tissues in stargardt disease type 1 and geographic atrophy patients.

Health Care · Biotechnology: Pharmaceutical Preparations · 41 employees

About Rhythm Pharmaceuticals

RYTM stock →

Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the rare neuroendocrine diseases in the United States and internationally. The company's lead product candidate is IMCIVREE (setmelanotide), a rare melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, Bardet-Biedl and Alström syndrome, Prader-Willi syndrome, and hypothalamic obesity.

Health Care · Biotechnology: Pharmaceutical Preparations · 414 employees

BLTE vs RYTM FAQ

Which is bigger, Belite Bio or Rhythm Pharmaceuticals?

Belite Bio (BLTE) is larger, with a market capitalization of $6.29B compared with $6.09B for Rhythm Pharmaceuticals (RYTM).

Which stock has performed better over the past year, BLTE or RYTM?

BLTE returned +101.65% over the past 12 months, compared with -11.40% for RYTM (price return, excluding dividends). Past performance does not predict future results.

Are Belite Bio and Rhythm Pharmaceuticals in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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