MetaCap

Clene (CLNN) vs Talphera (TLPH)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Talphera (TLPH) has outperformed Clene (CLNN) over the past year, losing 16.7% versus a loss of 56.8%. Over five years, TLPH leads with a -94.9% price change compared with -96.8% for CLNN. Clene is the larger company by market cap ($55.7 million vs $54.5 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

CLNN-56.78%TLPH-16.67%
+43%-13%-69%
Oct 7, 20251 yearOct 7, 2026
CLNN-97.14%TLPH-94.70%
+8%-48%-103%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

CLNN versus TLPH key metrics
MetricCLNNTLPH
Share price$3.92$1.05
Market cap$55.72M$54.50M
1-day change+1.29%-5.41%
YTD return-33.22%-7.89%
1-year return-56.78%-16.67%
5-year return-96.82%-94.85%
EPS (TTM)$-3.52$-0.26
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$13.50$1.57
52-week low$3.25$0.69
Distance from 52-week high-70.96%-33.12%
Average volume100.64K251.36K
Shares outstanding14.21M51.91M
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • TLPH has outperformed CLNN by 40.1 percentage points over the past year.

CLNN vs TLPH FAQ

Which is bigger, Clene or Talphera?

Clene (CLNN) is larger, with a market capitalization of $55.72M compared with $54.50M for Talphera (TLPH).

Which stock has performed better over the past year, CLNN or TLPH?

TLPH returned -16.67% over the past 12 months, compared with -56.78% for CLNN (price return, excluding dividends). Past performance does not predict future results.

Are Clene and Talphera in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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