Collegium Pharmaceutical (COLL) vs Tilray Brands (TLRY)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Collegium Pharmaceutical (COLL) has outperformed Tilray Brands (TLRY) over the past year, losing 34.3% versus a loss of 78.3%. Over five years, COLL leads with a +4.5% price change compared with -96.4% for TLRY. Collegium Pharmaceutical is the larger company by market cap ($710.2 million vs $519.5 million), about 1.4 times the size.
On valuation, Collegium Pharmaceutical trades at a lower forward P/E (3.3x vs 19.8x for Tilray Brands).
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | COLL | TLRY |
|---|---|---|
| Share price | $21.82 | $3.52 |
| Market cap | $710.20M | $519.45M |
| 1-day change | -0.52% | -5.38% |
| YTD return | -52.63% | -58.86% |
| 1-year return | -34.32% | -78.27% |
| 5-year return | +4.53% | -96.37% |
| P/E ratio (TTM) | 17.18 | — |
| Forward P/E | 3.28 | 19.80 |
| EPS (TTM) | $1.27 | $-1.09 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $50.79 | $23.20 |
| 52-week low | $21.43 | $3.38 |
| Distance from 52-week high | -57.05% | -84.85% |
| Analyst consensus | strong_buy | buy |
| Avg. price target upside | +124.62% | +103.70% |
| Average volume | 748.29K | 4.07M |
| Shares outstanding | 32.56M | 147.78M |
| Employees | 423 | 3,595 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Medicinal Chemicals and Botanical Products |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- COLL has outperformed TLRY by 44.0 percentage points over the past year.
About Collegium Pharmaceutical
COLL stock →Collegium Pharmaceutical, Inc., a specialty pharmaceutical company, engages in the development and commercialization of medicines for pain management. The company's portfolio includes Jornay PM, a central nervous system stimulant prescription medicine that contains methylphenidate HCl for the treatment of attention deficit hyperactivity disorder; Belbuca, a buccal film that contains buprenorphine for severe and persistent pain that requires an extended treatment period; Xtampza ER, an abuse-deterrent, extended-release, oral formulation of oxycodone for the management of pain severe enough to require daily; Nucynta ER and Nucynta IR, which are extended-release and immediate-release oral formulations of tapentadol, indicated for the management of acute, severe, and persistent pain; and Symproic, an oral formulation of naldemedine for the treatment of opioid-induced constipation in adult patients with chronic non-cancer pain.
Health Care · Biotechnology: Pharmaceutical Preparations · 423 employees
About Tilray Brands
TLRY stock →Tilray Brands, Inc., a lifestyle consumer products company, engages in the research, cultivation, processing, and distribution of medical cannabis products in Canada, the United States, Europe, the Middle East, Africa, and internationally. The company operates through four segments: Beverage, Cannabis, Distribution, and Wellness.
Health Care · Medicinal Chemicals and Botanical Products · 3,595 employees
COLL vs TLRY FAQ
Which is bigger, Collegium Pharmaceutical or Tilray Brands?
Collegium Pharmaceutical (COLL) is larger, with a market capitalization of $710.20M compared with $519.45M for Tilray Brands (TLRY).
Which stock has performed better over the past year, COLL or TLRY?
COLL returned -34.32% over the past 12 months, compared with -78.27% for TLRY (price return, excluding dividends). Past performance does not predict future results.
Are Collegium Pharmaceutical and Tilray Brands in the same industry?
Both are in the Health Care sector, but in different industries: Biotechnology: Pharmaceutical Preparations for Collegium Pharmaceutical and Medicinal Chemicals and Botanical Products for Tilray Brands.