Ionis Pharmaceuticals (IONS) Options Chain

NASDAQ: IONSHealth CareBiotechnology: Pharmaceutical PreparationsUSD

43.27-0.89 (-2.02%)

Market open · Delayed 15 min · as of Oct 8, 3:50 PM ET

Expiration date

Expiration: Oct 16, 2026
Days to expiration: 8
Share price: $43.30
Put/call ratio (OI): 0.72
Put/call ratio (volume): 22.86
ATM implied volatility: 49.8%
Expected move: ±$3.19
Open interest (C / P): 15.31K / 11.01K

IONS options summary

The IONS options chain for the October 16, 2026 expiration lists 30 call and 19 put contracts, with 8 days until expiration. Open interest stands at 15,308 calls and 11,005 puts, a put/call ratio of 0.72, which is fairly balanced between calls and puts. At-the-money implied volatility near the $42.50 strike is 49.8%, which implies the market expects a move of about ±$3.19 (7.4%) in Ionis Pharmaceuticals stock by expiration.

The most open interest sits at the $60.00 call (2.37K contracts) and the $40.00 put (3.31K contracts).

Summary generated from market data by MetaCap's automated system. Methodology

IONS options chain · October 16, 2026

IONS calls and puts by strike price. Shaded cells are in the money.
Calls							Puts
OI	Vol	IV	Last	Bid	Ask	Strike	Bid	Ask	Last	IV	Vol	OI
0	6	—	24.75	0.00	0.00	35.00	0.00	0.75	0.10	111.9%	—	4
—	—	—	—	—	—	37.50	0.00	0.30	0.25	65.2%	10	73
263	22	63.4%	3.70	3.20	4.40	40.00	0.10	0.35	0.20	55.1%	3	3,314
28	11	56.5%	2.16	1.25	1.95	42.50	0.60	0.80	0.70	43.1%	1	557
IONS $43.30
265	10	50.2%	0.75	0.45	0.70	45.00	1.60	2.50	1.70	54.2%	1	852
66	1	59.0%	0.20	0.05	0.35	47.50	2.70	4.70	3.60	67.2%	1	146
2,032	1	60.5%	0.15	0.05	0.20	50.00	5.00	8.20	6.65	136.9%	21	842
768	10	75.8%	0.10	0.05	0.20	52.50	8.00	9.70	7.00	107.0%	1	3,286
1,899	50	68.8%	0.05	0.00	0.05	55.00	10.00	13.10	10.00	174.3%	2,600	716
1,695	4	93.8%	0.05	0.00	0.15	57.50	12.50	16.00	12.50	87.9%	300	271
2,373	5	89.8%	0.05	0.00	0.05	60.00	14.80	18.50	15.12	229.1%	2,140	527
490	2	99.2%	0.05	0.00	0.05	62.50	17.30	21.00	16.40	245.1%	172	2
517	3	118.4%	0.04	0.00	0.10	65.00	19.80	23.50	6.65	260.2%	12	0
118	1	179.7%	0.05	0.00	0.75	67.50	22.20	26.00	22.20	274.2%	760	200
1,621	20	190.6%	0.05	0.00	0.75	70.00	24.80	28.50	25.46	287.5%	4	0
168	50	132.8%	0.10	0.00	0.05	72.50	—	—	—	—	—	—
453	1	152.3%	0.60	0.00	0.10	75.00	12.60	16.00	10.95	—	10	12
28	2	219.9%	0.75	0.00	0.75	77.50	19.80	23.90	9.47	—	3	3
1,584	2	212.5%	0.05	0.00	0.50	80.00	20.10	24.10	24.92	—	200	200
515	3	234.4%	0.05	0.00	0.70	82.50	0.00	0.00	9.50	—	2	0
96	43	167.2%	0.22	0.00	0.05	85.00	—	—	—	—	—	—
34	2	259.8%	0.10	0.00	0.85	87.50	—	—	—	—	—	—
28	10	270.3%	0.35	0.00	0.90	90.00	—	—	—	—	—	—
18	3	334.4%	0.35	0.00	2.15	92.50	—	—	—	—	—	—
227	1	342.4%	0.20	0.00	2.15	95.00	—	—	—	—	—	—
7	4	200.0%	0.10	0.00	0.05	100.00	—	—	—	—	—	—
2	1	371.8%	0.10	0.00	2.15	105.00	—	—	—	—	—	—
4	2	313.9%	0.85	0.00	0.75	110.00	—	—	—	—	—	—
3	1	399.7%	0.85	0.00	2.20	115.00	—	—	—	—	—	—
3	1	419.5%	0.95	0.00	2.40	120.00	—	—	—	—	—	—
3	1	447.9%	1.15	0.00	2.85	125.00	—	—	—	—	—	—

In-the-money callsIn-the-money puts. IV = implied volatility, OI = open interest (contracts). Each contract covers 100 shares. Quotes delayed at least 15 minutes.

Frequently asked questions

What is the IONS put/call ratio?

For the October 16, 2026 expiration, the IONS put/call ratio based on open interest is 0.72 (11,005 puts vs 15,308 calls), and 22.86 based on today's volume. A ratio above 1 means more puts than calls.

What is IONS's implied volatility?

At-the-money implied volatility for IONS options expiring October 16, 2026 is about 49.8%, an annualized estimate of how much the market expects Ionis Pharmaceuticals stock to move.

How many IONS option expiration dates are there?

IONS has 8 listed expiration dates, from Oct 16, 2026 to Jan 19, 2029.

What does "in the money" mean?

A call is in the money when the strike price is below the current share price; a put is in the money when the strike is above it. In-the-money contracts have intrinsic value and are shaded in the table.