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Ionis Pharmaceuticals Insider Trades

NASDAQ: IONSHealth CareBiotechnology: Pharmaceutical PreparationsUSD

45.45+2.15 (+4.97%)

Market open · Delayed 15 min · as of Oct 9, 1:41 PM ET

Last 12 months

Purchases
2 · $1.06M
Sales
33 · $30.49M
Shares bought / sold
20.00K / 394.70K
Net activity
Net selling $29.4 million

Ionis Pharmaceuticals insider activity

Over the last 12 months, Ionis Pharmaceuticals insiders reported 70 transactions on SEC Form 4: 2 open-market purchases and 33 sales. Insiders bought $1.1 million and sold $30.5 million worth of stock, for net insider selling of $29.4 million. The largest seller was Monia Brett P, with $7.2 million in reported sales.

The most recent filing shows Monia Brett P (Chief Executive Officer) reporting a transaction in 98 shares at $51.31 on Aug 31, 2026. Insider sales are common for compensation, tax and diversification reasons, while open-market purchases are rarer; tracking both helps put IONS's ownership changes in context.

Summary generated from market data by MetaCap's automated system. Methodology

IONS insider transactions

Ionis Pharmaceuticals insider transactions
DateInsiderTypeSharesValueFiling
Aug 31, 2026Birchler BrianEVP, Corp and Development Opsother58$2.98KForm 4
Aug 31, 2026O'NEIL PATRICK R.EVP CLO & General Counselother63$3.23KForm 4
Aug 31, 2026BENNETT C FRANKEVP, Chief Scientific Officerother110$5.64KForm 4
Aug 31, 2026Monia Brett PChief Executive Officerother98$5.03KForm 4
Jul 31, 2026Hayden Michael RDirectorBuy5,000$258.00KForm 4
Jul 30, 2026Hayden Michael RDirectorBuy15,000$800.70KForm 4
Jul 15, 2026BERTHELSEN SPENCER RDirectorOption exercise5,220—Form 4
Jul 15, 2026HERMAN JOAN EDirectorOption exercise5,220—Form 4
Jul 7, 2026Diaz Allene M.DirectorSale10,111$863.64KForm 4
Jul 7, 2026Diaz Allene M.DirectorOption exercise10,111$476.33KForm 4
Jul 7, 2026BENNETT C FRANKEVP, Chief Scientific OfficerSale15,000$1.28MForm 4
Jul 7, 2026BENNETT C FRANKEVP, Chief Scientific Officerother15,000—Form 4
Jul 7, 2026BENNETT C FRANKEVP, Chief Scientific OfficerSale5,536$462.69KForm 4
Jul 7, 2026Kordasiewicz Holly B.EVP, Chief Development OfficerSale362$30.52KForm 4
Jul 1, 2026KLEIN JOSEPH IIIDirectorSale11,419$902.55KForm 4
Jul 1, 2026KLEIN JOSEPH IIIDirectorSale99$7.87KForm 4
Jul 1, 2026KLEIN JOSEPH IIIDirectorOption exercise11,518$460.03KForm 4
Jun 26, 2026Monia Brett PChief Executive OfficerSale50,000$4.03MForm 4
Jun 26, 2026Monia Brett PChief Executive OfficerOption exercise50,000$2.84MForm 4
Jun 26, 2026O'NEIL PATRICK R.EVP CLO & General CounselSale3,069$245.52KForm 4
Jun 26, 2026Schneider EugeneEVP, Chf Clinical Develop OfcrSale26,000$2.11MForm 4
Jun 26, 2026Schneider EugeneEVP, Chf Clinical Develop OfcrOption exercise26,000$1.58MForm 4
Jun 26, 2026Baroldi JosephEVP, Chief Business OfficerSale5,635$451.70KForm 4
Jun 26, 2026Baroldi JosephEVP, Chief Business OfficerOption exercise1,769$57.67KForm 4
Jun 26, 2026Baroldi JosephEVP, Chief Business OfficerOption exercise3,866$219.51KForm 4
Jun 25, 2026Swayze EricEVP ResearchSale10,602$839.49KForm 4
Jun 25, 2026Monia Brett PChief Executive OfficerSale21,072$1.65MForm 4
Jun 25, 2026Monia Brett PChief Executive OfficerOption exercise21,072$686.95KForm 4
Jun 24, 2026Monia Brett PChief Executive OfficerSale14,565$1.14MForm 4
Jun 24, 2026Monia Brett PChief Executive OfficerOption exercise14,565$474.82KForm 4
Jun 15, 2026BERTHELSEN SPENCER RDirectorSale8,000$587.92KForm 4
Jun 15, 2026BERTHELSEN SPENCER RDirectorOption exercise8,000$195.36KForm 4
Jun 12, 2026Kordasiewicz Holly B.EVP, Chief Development OfficerSale19,842$1.47MForm 4
Jun 12, 2026Kordasiewicz Holly B.EVP, Chief Development OfficerSale41,004$3.00MForm 4
Jun 12, 2026Kordasiewicz Holly B.EVP, Chief Development OfficerOption exercise19,895$1.13MForm 4
Jun 12, 2026Kordasiewicz Holly B.EVP, Chief Development OfficerOption exercise12,000$391.20KForm 4
Jun 12, 2026Kordasiewicz Holly B.EVP, Chief Development OfficerOption exercise21,000$1.28MForm 4
Jun 12, 2026Kordasiewicz Holly B.EVP, Chief Development OfficerOption exercise7,951$484.14KForm 4
Jun 1, 2026BERTHELSEN SPENCER RDirectorSale8,000$605.36KForm 4
Jun 1, 2026BERTHELSEN SPENCER RDirectorOption exercise8,000$195.36KForm 4
May 14, 2026Monia Brett PChief Executive OfficerSale3,220$253.35KForm 4
May 14, 2026Monia Brett PChief Executive OfficerOption exercise3,220$104.97KForm 4
May 13, 2026Monia Brett PChief Executive OfficerSale1,316$102.67KForm 4
May 13, 2026Monia Brett PChief Executive OfficerOption exercise1,316$42.90KForm 4
May 4, 2026LOSCALZO JOSEPHDirectorSale17,781$1.34MForm 4
May 4, 2026LOSCALZO JOSEPHDirectorSale59,508$4.46MForm 4
May 4, 2026LOSCALZO JOSEPHDirectorOption exercise16,000$1.04MForm 4
May 4, 2026LOSCALZO JOSEPHDirectorOption exercise12,000$722.40KForm 4
May 4, 2026LOSCALZO JOSEPHDirectorOption exercise16,000$686.08KForm 4
May 4, 2026LOSCALZO JOSEPHDirectorOption exercise10,321$423.99KForm 4
May 4, 2026LOSCALZO JOSEPHDirectorOption exercise12,000$480.60KForm 4
May 4, 2026LOSCALZO JOSEPHDirectorOption exercise10,968$417.44KForm 4
May 1, 2026KLEIN JOSEPH IIIDirectorSale1,431$106.53KForm 4
May 1, 2026KLEIN JOSEPH IIIDirectorSale8,680$636.70KForm 4
May 1, 2026KLEIN JOSEPH IIIDirectorOption exercise10,111$476.33KForm 4
Apr 28, 2026Baroldi JosephEVP, Chief Business OfficerSale1,626$116.73KForm 4
Apr 16, 2026Baroldi JosephEVP, Chief Business OfficerSale5,619$418.95KForm 4
Apr 16, 2026Birchler BrianEVP, Corp and Development OpsSale973$73.02KForm 4
Apr 16, 2026Jenne KyleEVP, Chf GL Pdt Str OfcrSale4,902$368.49KForm 4
Apr 15, 2026Baroldi JosephEVP, Chief Business OfficerOption exercise10,837—Form 4
Apr 15, 2026Birchler BrianEVP, Corp and Development OpsOption exercise1,875—Form 4
Apr 15, 2026Jenne KyleEVP, Chf GL Pdt Str OfcrOption exercise12,226—Form 4
Apr 15, 2026PARSHALL B LYNNEDirectorSale534$41.10KForm 4
Apr 15, 2026PARSHALL B LYNNEDirectorSale4,466$340.26KForm 4
Apr 2, 2026Devers Shannon L.EVP, Chief Human Resources OfcSale6,193$458.61KForm 4
Apr 1, 2026KLEIN JOSEPH IIIDirectorSale2,216$168.31KForm 4
Apr 1, 2026KLEIN JOSEPH IIIDirectorSale20,105$1.52MForm 4
Apr 1, 2026KLEIN JOSEPH IIIDirectorOption exercise10,321$423.99KForm 4
Apr 1, 2026KLEIN JOSEPH IIIDirectorOption exercise12,000$456.72KForm 4
Mar 19, 2026Schneider EugeneEVP, Chf Clinical Develop OfcrSale5,812$412.49KForm 4

Transaction codes follow SEC Form 4: P = open-market purchase, S = open-market sale, A = grant or award, M = option exercise, F = shares withheld for taxes. About Form 4

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