Annovis Bio (ANVS) vs Clene (CLNN)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Annovis Bio (ANVS) has outperformed Clene (CLNN) over the past year, losing 46.5% versus a loss of 56.8%. Over five years, ANVS leads with a -95.7% price change compared with -96.8% for CLNN. Clene is the larger company by market cap ($55.7 million vs $51.6 million), about 1.1 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | ANVS | CLNN |
|---|---|---|
| Share price | $1.21 | $3.92 |
| Market cap | $51.64M | $55.72M |
| 1-day change | +2.54% | +1.29% |
| YTD return | -65.03% | -33.22% |
| 1-year return | -46.46% | -56.78% |
| 5-year return | -95.68% | -96.82% |
| EPS (TTM) | $-1.79 | $-3.52 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $5.50 | $13.50 |
| 52-week low | $1.04 | $3.25 |
| Distance from 52-week high | -78.00% | -70.96% |
| Average volume | 895.73K | 100.64K |
| Shares outstanding | 42.68M | 14.21M |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- ANVS has outperformed CLNN by 10.3 percentage points over the past year.
ANVS vs CLNN FAQ
Which is bigger, Annovis Bio or Clene?
Clene (CLNN) is larger, with a market capitalization of $55.72M compared with $51.64M for Annovis Bio (ANVS).
Which stock has performed better over the past year, ANVS or CLNN?
ANVS returned -46.46% over the past 12 months, compared with -56.78% for CLNN (price return, excluding dividends). Past performance does not predict future results.
Are Annovis Bio and Clene in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.