Ionis Pharmaceuticals (IONS) Options Chain

NASDAQ: IONSHealth CareBiotechnology: Pharmaceutical PreparationsUSD

45.28+1.98 (+4.57%)

At close: Oct 9, 4:00 PM ET · Delayed 15 min

Expiration date

Expiration: Nov 20, 2026
Days to expiration: 40
Share price: $45.28
Put/call ratio (OI): 0.87
Put/call ratio (volume): 0.12
ATM implied volatility: 56.2%
Expected move: ±$8.42
Open interest (C / P): 1.93K / 1.67K

IONS options summary

The IONS options chain for the November 20, 2026 expiration lists 13 call and 13 put contracts, with 40 days until expiration. Open interest stands at 1,925 calls and 1,669 puts, a put/call ratio of 0.87, which is fairly balanced between calls and puts. At-the-money implied volatility near the $45.00 strike is 56.2%, which implies the market expects a move of about ±$8.42 (18.6%) in Ionis Pharmaceuticals stock by expiration.

The most open interest sits at the $50.00 call (1.30K contracts) and the $40.00 put (571 contracts).

Summary generated from market data by MetaCap's automated system. Methodology

IONS options chain · November 20, 2026

IONS calls and puts by strike price. Shaded cells are in the money.
Calls							Puts
OI	Vol	IV	Last	Bid	Ask	Strike	Bid	Ask	Last	IV	Vol	OI
—	—	—	—	—	—	32.50	0.00	0.55	0.40	67.6%	3	4
—	—	—	—	—	—	35.00	0.00	1.20	0.60	68.6%	1	44
—	—	—	—	—	—	37.50	0.05	1.00	1.00	52.5%	11	40
109	1	64.6%	5.41	5.30	8.50	40.00	0.60	2.00	1.80	57.8%	2	571
—	—	—	—	—	—	42.50	1.15	2.80	2.75	54.1%	10	30
104	2	59.5%	3.81	2.65	4.80	45.00	2.00	4.10	3.20	52.9%	10	455
IONS $45.28
89	2	51.5%	2.10	1.60	2.80	47.50	3.20	5.00	4.50	61.2%	1	368
1,296	14	59.9%	1.70	0.75	1.90	50.00	4.90	7.30	6.80	50.4%	1	58
52	61	55.6%	1.25	0.45	1.75	52.50	7.10	10.10	2.40	61.3%	—	1
144	6	55.3%	0.85	0.45	0.95	55.00	8.30	12.40	11.70	53.5%	2	14
—	—	—	—	—	—	57.50	10.60	14.70	6.10	55.0%	1	37
43	20	65.0%	0.30	0.10	0.95	60.00	12.90	16.90	14.88	50.8%	5	14
1	—	69.7%	5.00	0.00	0.95	62.50	15.40	19.30	17.76	53.1%	5	33
32	326	74.7%	0.20	0.20	0.70	65.00	—	—	—	—	—	—
10	4	77.0%	0.15	0.00	0.75	67.50	—	—	—	—	—	—
37	10	86.6%	0.10	0.00	0.95	70.00	—	—	—	—	—	—
2	1	84.9%	0.10	0.00	0.50	75.00	—	—	—	—	—	—
6	2	106.5%	0.46	0.00	1.00	80.00	—	—	—	—	—	—

In-the-money callsIn-the-money puts. IV = implied volatility, OI = open interest (contracts). Each contract covers 100 shares. Quotes delayed at least 15 minutes.

Frequently asked questions

What is the IONS put/call ratio?

For the November 20, 2026 expiration, the IONS put/call ratio based on open interest is 0.87 (1,669 puts vs 1,925 calls), and 0.12 based on today's volume. A ratio above 1 means more puts than calls.

What is IONS's implied volatility?

At-the-money implied volatility for IONS options expiring November 20, 2026 is about 56.2%, an annualized estimate of how much the market expects Ionis Pharmaceuticals stock to move.

How many IONS option expiration dates are there?

IONS has 8 listed expiration dates, from Oct 16, 2026 to Jan 19, 2029.

What does "in the money" mean?

A call is in the money when the strike price is below the current share price; a put is in the money when the strike is above it. In-the-money contracts have intrinsic value and are shaded in the table.