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Karyopharm Therapeutics (KPTI) Options Chain

NASDAQ: KPTIHealth CareBiotechnology: Pharmaceutical PreparationsUSD

0.60-0.045 (-6.98%)

At close: Oct 8, 4:00 PM ET · Delayed 15 min

Pre-market: 0.6162 +2.70%

Expiration date

Expiration
Oct 16, 2026
Days to expiration
7
Share price
$0.60
Put/call ratio (OI)
0.03
Put/call ratio (volume)
1.68
Expected move
±$0.0415
Open interest (C / P)
20.67K / 685

KPTI options summary

The KPTI options chain for the October 16, 2026 expiration lists 6 call and 4 put contracts, with 7 days until expiration. Open interest stands at 20,673 calls and 685 puts, a put/call ratio of 0.03, which is tilted bullish, with calls outnumbering puts. At-the-money implied volatility near the $0.50 strike is 50.0%, which implies the market expects a move of about ±$0.0415 (6.9%) in Karyopharm Therapeutics stock by expiration.

The most open interest sits at the $2.50 call (12.84K contracts) and the $0.50 put (234 contracts).

Summary generated from market data by MetaCap's automated system. Methodology

KPTI options chain · October 16, 2026

KPTI calls and puts by strike price. Shaded cells are in the money.
CallsPuts
LastBidAskStrikeBidAskLast
0.250.000.000.500.000.000.06
0.050.000.001.000.000.000.35
0.050.000.001.500.000.000.87
0.250.000.002.000.000.001.30
0.050.000.002.50———
0.050.000.005.00———

In-the-money callsIn-the-money puts. IV = implied volatility, OI = open interest (contracts). Each contract covers 100 shares. Quotes delayed at least 15 minutes.

Frequently asked questions

What is the KPTI put/call ratio?

For the October 16, 2026 expiration, the KPTI put/call ratio based on open interest is 0.03 (685 puts vs 20,673 calls), and 1.68 based on today's volume. A ratio above 1 means more puts than calls.

What is KPTI's implied volatility?

At-the-money implied volatility for KPTI options expiring October 16, 2026 is about 50.0%, an annualized estimate of how much the market expects Karyopharm Therapeutics stock to move.

How many KPTI option expiration dates are there?

KPTI has 7 listed expiration dates, from Oct 16, 2026 to Jan 19, 2029.

What does "in the money" mean?

A call is in the money when the strike price is below the current share price; a put is in the money when the strike is above it. In-the-money contracts have intrinsic value and are shaded in the table.

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