Karyopharm Therapeutics (KPTI) Options Chain

NASDAQ: KPTIHealth CareBiotechnology: Pharmaceutical PreparationsUSD

0.605+0.005 (+0.83%)

At close: Oct 9, 4:00 PM ET · Delayed 15 min

Expiration date

Expiration: Jan 21, 2028
Days to expiration: 468
Share price: $0.605
Put/call ratio (OI): 50.94
Put/call ratio (volume): 9.60
ATM implied volatility: 188.3%
Expected move: ±$1.29
Open interest (C / P): 200 / 10.19K

KPTI options summary

The KPTI options chain for the January 21, 2028 expiration lists 12 call and 8 put contracts, with 468 days until expiration. Open interest stands at 200 calls and 10,188 puts, a put/call ratio of 50.94, which is more bearish, with puts outnumbering calls. At-the-money implied volatility near the $0.50 strike is 188.3%, which implies the market expects a move of about ±$1.29 (213.2%) in Karyopharm Therapeutics stock by expiration.

The most open interest sits at the $2.00 call (60 contracts) and the $0.50 put (8.72K contracts).

Summary generated from market data by MetaCap's automated system. Methodology

KPTI options chain · January 21, 2028

KPTI calls and puts by strike price. Shaded cells are in the money.
Calls							Puts
OI	Vol	IV	Last	Bid	Ask	Strike	Bid	Ask	Last	IV	Vol	OI
1	1	231.3%	0.55	0.00	1.00	0.50	0.15	0.40	0.30	145.3%	100	8,718
KPTI $0.605
4	—	262.5%	1.70	0.00	1.00	1.00	0.45	1.30	0.65	246.9%	200	702
15	15	303.1%	0.38	0.05	1.00	1.50	1.10	1.90	0.98	—	150	456
60	5	290.6%	0.40	0.00	1.00	2.00	1.55	2.55	1.32	—	—	3
33	10	—	0.42	0.15	1.15	2.50	1.70	2.70	1.80	193.0%	—	60
26	7	525.0%	0.95	0.10	1.10	5.00	4.00	5.00	4.00	144.5%	20	151
0	5	50.0%	2.46	0.00	0.00	7.50	6.40	7.40	6.10	93.8%	—	86
38	5	343.8%	0.20	0.00	1.00	10.00	8.90	9.90	8.50	100.0%	10	12
2	—	350.0%	3.00	0.00	1.00	12.50	—	—	—	—	—	—
12	—	—	2.90	1.50	6.50	15.00	—	—	—	—	—	—
9	—	—	3.49	0.50	5.50	17.50	—	—	—	—	—	—
0	2	50.0%	2.11	0.00	0.00	20.00	—	—	—	—	—	—

In-the-money callsIn-the-money puts. IV = implied volatility, OI = open interest (contracts). Each contract covers 100 shares. Quotes delayed at least 15 minutes.

Frequently asked questions

What is the KPTI put/call ratio?

For the January 21, 2028 expiration, the KPTI put/call ratio based on open interest is 50.94 (10,188 puts vs 200 calls), and 9.60 based on today's volume. A ratio above 1 means more puts than calls.

What is KPTI's implied volatility?

At-the-money implied volatility for KPTI options expiring January 21, 2028 is about 188.3%, an annualized estimate of how much the market expects Karyopharm Therapeutics stock to move.

How many KPTI option expiration dates are there?

KPTI has 7 listed expiration dates, from Oct 16, 2026 to Jan 19, 2029.

What does "in the money" mean?

A call is in the money when the strike price is below the current share price; a put is in the money when the strike is above it. In-the-money contracts have intrinsic value and are shaded in the table.