MetaCap

Who Owns Spyre Therapeutics Stock?

NASDAQ: SYREHealth CareBiotechnology: Pharmaceutical PreparationsUSD

85.69+5.79 (+7.25%)

At close: Oct 9, 4:00 PM ET · Delayed 15 min

Ownership breakdown

Held by institutions
106.80%
Institutional holders
382
  • Institutions 98.4%
  • Insiders 1.6%
  • Public and other 0.0%

Who owns Spyre Therapeutics stock?

Institutional investors own about 106.8% of Spyre Therapeutics's shares, spread across 382 institutions that file 13F reports. That level of institutional ownership is high, typical of large, widely followed companies. Insiders, including executives, directors and large founding shareholders, hold 1.58% of SYRE.

The largest institutional holders are FMR, LLC (12.78%), Blackrock Inc. (6.38%) and Perceptive Advisors Llc (4.24%). Together, the top 10 institutions control 46.3% of shares outstanding. In their latest filings, 9 of the top 10 institutions increased their SYRE positions and 1 reduced them.

Summary generated from market data by MetaCap's automated system. Methodology

Top institutional holders of SYRE

Spyre Therapeutics top institutional holders
InstitutionShares% HeldChange
FMR, LLC13.03M12.78%+10.6%
Blackrock Inc.6.51M6.38%+17.9%
Perceptive Advisors Llc4.32M4.24%+14.2%
RTW Investments LP4.25M4.17%+1.9%
Paradigm Biocapital Advisors LP3.84M3.77%+96.2%
Vanguard Capital Management LLC3.45M3.38%+12.8%
State Street Corporation3.06M3.00%+17.3%
Venrock Adviser, LLC2.99M2.93%-19.0%
Price (T.Rowe) Associates Inc2.96M2.91%+85.2%
Driehaus Capital Management, LLC2.80M2.75%+0.3%

% held is the share of total shares outstanding. Change is the percentage change in the position since the holder's previous 13F filing.

Top mutual fund and ETF holders of SYRE

Spyre Therapeutics top fund holders
FundShares% Held
SmallCap World Fund Inc2.78M2.73%
Fidelity Mt. Vernon Street Trust-Fidelity Growth Company Fund2.76M2.71%
VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund2.48M2.44%
iShares Trust-iShares Russell 2000 ETF1.90M1.86%
SPDR SERIES TRUST-State Street SPDR S&P Biotech ETF1.40M1.37%
VANGUARD INDEX FUNDS-Vanguard Small-Cap Index Fund896.56K0.88%
VANGUARD INDEX FUNDS-Vanguard Extended Market Index Fund886.18K0.87%
Fidelity Advisor Series VII-Fidelity Advisor Biotechnology Fund857.35K0.84%
Fidelity Salem Street Trust-Fidelity Small Cap Index Fund814.29K0.80%
Fidelity Mt. Vernon Street Trust-Fidelity Growth Company K6 Fund804.72K0.79%

Frequently asked questions

Who is the largest shareholder of Spyre Therapeutics?

FMR, LLC is the largest institutional shareholder of SYRE, owning 12.78% of shares outstanding (13.03M shares) as of its latest 13F filing.

What percentage of Spyre Therapeutics is owned by institutions?

Institutions own about 106.8% of SYRE shares and 108.5% of the public float.

How much of Spyre Therapeutics do insiders own?

Insiders, such as officers and directors, own about 1.58% of SYRE shares outstanding.

Where does institutional ownership data come from?

Investment managers with more than $100 million in US equities must file Form 13F with the SEC within 45 days of each quarter-end. Holdings are therefore up to about 4.5 months old when published.

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